Major breakthrough in cancer research

Astronomers just detected a potentially hazardous 0.9-mile-wide asteroid hiding in the Sun's glare. Nov 01, 2022 [Blueprint]( Shedding light on dark matter... But we’re not talking space and the universe here, we’re talking something much closer to home – namely, cancer treatment. Because two major new studies have uncovered a [new level of control of cancer gene activity]( within tumors, termed cancer's “dark matter.” The revelation shows that epigenetics (which are the cells that control gene activity) play a crucial role in the development of cancer. And the thing is, cancers are usually tested for DNA mutations alone, which can miss this level of control. So this could really help predict how cancers may behave and respond to treatment. But before you get swept away by that, why not imagine getting swept away by [this video]( It shows a new DeLorean that’s been built by the late John DeLorean’s daughter, and it’s just as great as you’d imagine. Good morning. I’m Alice, an Editor at IE. This is The Blueprint. Let’s dive in. Last Sunday, Blueprint subscribers had scientists insights on whether killer robots are going to take over the world (and what we can do about it). Don't miss out — [subscribe to IE+]( today to receive exclusive interviews, features, and much more. [Play]VIDEO OF THE DAY [Engineering tribute: Late John DeLorean’s daughter builds new car in his honor.]( [Late John DeLorean’s daughter builds new car in his honor.]( “Roads? Where we're going, we don't need roads.” [Must Read]MUST READ [Major breakthrough in cancer research: Papers reveal 'dark matter' that contributes to disease's growth.]( [Major breakthrough in cancer research]( [Two new cancer research studies]( have made a major breakthrough, in as much as they have uncovered a new level of control of cancer gene activity within tumors, (which are known as cancer's “dark matter”.) This essentially means that researchers have found a new way to predict and affect how cancers behave. Previously, the focus has largely been placed on genetic mutations, which permanently change the DNA code. But this new research shows that the way the DNA folds up can change which genes are read, without altering the DNA code. 1,373 samples from 30 bowel cancers were taken, and researchers then looked at epigenetic changes as the cancers grew. Their observations showed that epigenetic changes are common in cancerous cells, are heritable, and were present in cancer cells that had what it called “survival advantages.” → Researchers also looked at the DNA sequence in diverse samples taken from different parts of the same tumor. These revealed that less than two percent of “changes in the DNA code in independent areas of a tumor were associated with changes in gene activity and variation in cancer cell characteristics throughout tumors is often governed by factors other than DNA mutations”. [READ MORE [Arrow]]( [Facebook]( [Twitter]( [SCIENCE]SCIENCE [Astronomers just detected a potentially hazardous 0.9-mile-wide asteroid hiding in the Sun's glare.]( Astronomers have discovered [three near-Earth asteroids]( (NEAs) hiding in the inner Solar System, safely tucked in the glare of the Sun. One of them is an enormous asteroid, dubbed a “planet killer”, which could collide with Earth. [READ MORE [Arrow]]( And Other Stories in Science - Telescope captures the spooky [remains of a massive dead star](. - Harvard professor says there could be as many as [4 quintillion alien spacecraft]( flying near Earth. - How a thin coated film [could upgrade photosynthesis]( and feed 9 billion people. [premium] [INNOVATION]INNOVATION [Artificial intelligence might be able to treat various brain disorders.]( Certain brain disorders such as epilepsy and Parkinson’s disease could potentially be [treated using neural implants](. Researchers are combining artificial intelligence and microelectronics to create safe, effective technology. [READ MORE [Arrow]]( And Other Stories in Innovation - World's largest plane [flies with a hypersonic vehicle]( for the first time. - Russia completes debut flight of [upgraded Su-57]( its fifth generation fighter. - The first firm to get an Apollo 11 contract is helping [build NASA's Artemis software](. [premium] [MAIL & MUSINGS]MAIL & MUSINGS Major breakthrough in cancer research: Papers reveal 'dark matter' that contributes to disease's growth. How soon do you think these findings will change the way we approach cancer treatments? [Hopefully as soon as possible]( [I think it'll take years]( [It might not actually change anything]( [It’s hard to say]( YESTERDAY'S RESULTS Yesterday, we asked you if you think we'll ever fully understand what causes Alzheimer's, and 49 percent of you said yes, totally. Which is cheering. 49% Yes, for sure 31% Yes, but not in our lifetimes 16% It's impossible to say 3% No, not going to happen [QUOTE OF THE DAY]QUOTE OF THE DAY “I do not know what I may appear to the world, but to myself I seem to have been only like a boy playing on the seashore, and diverting myself in now and then finding a smoother pebble or a prettier shell than ordinary, whilst the great ocean of truth lay all undiscovered before me.” Isaac Newton. 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