Plus: CRISPR could lead to an HIV cure Apr 04, 2022 [View in browser]( Itâs only Monday, but the James Webb Space Telescope is already light-years ahead of schedule. The space-based telescope finished stage six of its seven-step set-up process, unfolding at unprecedented extremes of efficiency. But Webbâs frenetic, stop-and-go development record doesnât make it easy to slip into an optimistic paradigm. To reach stage six, NASA scientists underwent a painstaking process of slowly adjusting the parts of the telescope's primary mirror to align its gold-hue mirrors with several instruments. But, before we explore Webbâs next steps, we have the perfect video that shows how an elevator is built from start to finish. It's actually fascinating to watch. Good morning. Iâm Derya, an editor at IE. This is The Blueprint. Letâs lift you up. [Video]VIDEO OF THE DAY [Find out how an elevator is made from start to finish]( The process behind how elevators are made is actually fascinating to watch. [Find out how an elevator is made from start to finish]( SCIENCE [The James Webb Telescope finished aligning 3 of its 4 primary instruments]( [The James Webb Telescope.]( The James Webb Space Telescope is one of the greatest scientific endeavors of the 21st century that almost didn't happen, burdened as it was by years of delays and billions of dollars in overspending. - But the mission succeeded, and the telescope [has now completed]( the process of aligning three out of its four instruments. This step is the sixth in the process of aligning the tool's mirrors with its scientific instruments so that they can create the most accurate and focused images ever captured of the cosmos. Looking ahead. Thatâll happen once the Mid-Infrared Instrument fully cools to its cryogenic operating temperature. That step is set to take place in the weeks ahead and will ensure that final adjustments are made. Once itâs ready to deliver focused light to each of its instruments, a key decision meeting will occur to confirm the end of aligning the telescope. And then [the real fun begins](. [Read More]( INNOVATION [Raytheon wins the US Navy's SPY-6 radar contract that's worth $3.2 billion]( [Raytheon.]( Raytheon Missiles & Defense [was awarded a $3.2 billion contract]( to supply radar technology over five years, equipping up to 31 U.S. Navy ships with SPY-6 radars. Electronic warfare. Itâs estimated that since its inception, more than $600 million has been invested in the development of the SPY-6 family of radars to allow them to bring new capabilities to the surface fleet like advanced electronic warfare protection and enhanced detection abilities. - The latest move will deliver unprecedented integrated air and missile defense capabilities for seven types of U.S. Navy ships over the next 40 years. The new contract may see up to 46 radars provided to Navy ships by his firm, 15 more than initially presumed. The SPY-6 radar installation has already been completed on [the Navy's first Flight III destroyer]( the USS Jack H. Lucas (DDG 125). [Read More]( HEALTH [New advances in CRISPR gene-editing could lead to an HIV cure]( [HIV.]( Scientists at Northwestern Medicine are using new advances in CRISPR gene-editing technology [to uncover how HIV hijacks the bodyâs cells]( and hopefully lead to a new permanent treatment for the virus. - Through this process, they stumbled upon 86 genes that may play a role in the way HIV replicates, including more than 40 that had never been examined before in the context of HIV infection. How? The study looked at T cells, which HIV targets. They were isolated from human blood and hundreds of their genes were further knocked out using CRISPR. They were then infected with HIV. It was seen that when these cells lost a gene important for viral replication, HIV infection decreased, and when cells lost an antiviral factor, HIV infection increased. The researchers hope that the work will lead to engineering new treatments [that can become permanent cures](. [Read More]( MAIL & MUSINGS In just a few short years, CRISPR has had a tremendous impact on scientific research. Which CRISPR application gets you most excited? Be sure you check back tomorrow for the results! [Curing genetic diseases will be amazing.]( [De-extinction. Bring back the wooly mammoth!]( [Bioenergy. Weâll need it.]( [Allergy-free foods! They are often overlooked.]( Yesterdayâs Results New federal rules will force new vehicles sold in the U.S. to achieve an average of at least 40 miles per gallon of gasoline by 2026. We asked whether such a measure in transportation could decelerate climate change. The answers seem quite divided. Yes, every precaution matters. 29%
No, itâs just a trivial step taken to keep up with global moves. 29%
Maybe slightly, we need much faster and more extensive changes. 28%
Before that, large companies need to take measures to reduce their carbon footprints. 13% QUOTE OF THE DAY â People are beginning to see that the first requisite to success in life is to be a good animal. â Herbert Spencer in âEducationâ (1861) AND ANOTHER THING... - Mark Zuckerberg revealed that his employees [refer to him as the âEye of Sauronâ]( and that he likes the comparison.
- Treasure hunters believed theyâd [found $500 million in Civil War gold.]( Then the FBI swooped in. (Popular Mechanics)
- Lockheed Martin Sikorsky's Defiant helicopter [has completed its farthest flight so far]( in a 700-mile trip.
- Gas prices are rising â [you can try these eight strategies]( to save money at the pump. (CNBC)
- Ancient guiding lights: [what are constellations]( and how did they form?
- Particle accelerators started small, but to make groundbreaking discoveries, physicists had to think big â as in, vast machines with the [power to reveal the tiniest building blocks]( of our universe. (Knowable Magazine Podcast)
- Since the 1960s, U.S. astronomers gather every 10 years to create a priority list. What does [astronomy's wish list for the next decade]( include? [Share to Win]SHARE TO WIN [All products]( Share The Blueprint! Give your friends deeper insights into engineering and tech, and win exclusive IE swag for free. [Read Details]( Share your link Copy & share your referral link with others. [ [Referral Program Terms and Conditions]( Prepared by Derya Ozdemir and Brad Bergan Enjoy reading? Don't forget to forward to a friend! Was this email forwarded to you? [Subscribe]( [About Us]( | [Advertise]( | [Contact Us](
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