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A new form of gene editing progresses to human testing

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wired.com

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Fri, Dec 23, 2022 11:00 PM

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PLUS: The Metaverse Doesn’t Have a Leg to Stand On, and more. | ? BY KATE KNIBBS ? [The 4-D

PLUS: The Metaverse Doesn’t Have a Leg to Stand On, and more. [View this email in your browser]( | [Manage newsletter subscriptions](newsletter=wir) [12.23.22](   [A collage of a person wearing a VR headset looking off into a metaverse space ]( [YEAR IN REVIEW | 5-MINUTE READ]( [The Metaverse Doesn’t Have a Leg to Stand On]( BY KATE KNIBBS [It was a rocky year for the tech industry. To understand why, look no further than the "embodied internet."](   [comic strip illustrating the positive effects of a three-day weekend with a person dancing, walking a dog, reading, and doing an excellent job at work with praise from a coworker.]( [WIRED WORLD | 2-MINUTE READ]( [The 4-Day Work-Week Is (Almost) Here]( BY OMAR AL-UBAYDLI AND JOHN A. LIST [The three-day weekend may soon be a reality—but only if policymakers can think of proper countermeasures against voltage drops.](   [3D illustration of router with WiFi symbol floating above]( [SPEED BUMP | 7-MINUTE READ]( [11 Ways to Upgrade Your Wi-Fi and Make Your Internet Faster]( BY WIRED STAFF [From Wi-Fi extenders to simple wall brackets, there's always something you can do to improve your internet connection at home.](   [single helix strips of different colors]( [SPELL CHECK | 5-MINUTE READ]( [A More Elegant Form of Gene Editing Progresses to Human Testing]( BY EMILY MULLIN [Instead of cutting out chunks of the genome to disable malfunctioning genes, base editing makes a smaller, more precise swap.]( [GET WIRED]( [Get WIRED for just $29.99 $5. Includes the print edition plus editor in chief Gideon Lichfield's column, System Update.]([Subscribe now.](   [Stephen Curry throws his hands in the air and chews on his mouthguard]( [DOT PHYSICS | 7-MINUTE READ]( [How to Use Physics to Tell If That Steph Curry Video Is Real]( BY RHETT ALLAIN [Could the Golden State Warriors legend really sink five full-court shots in a row? Some clever modeling can give fans a clue.](   [illustration of a giant geometric figure resting in a reflective pose surrounded by colorful circles and squares and another small figure at standing by its feet. ]( [WIRED WORLD | 2-MINUTE READ]( [Conscious Machines May Never Be Possible]( BY ANIL SETH [People won’t be saying “It’s conscious!” about an AI in 2023—no matter how smart it may seem.](   [Coway Airmega 250 air purifier]( [BUYING GUIDE | 10-MINUTE READ]( [Breathe Easy—We Found the Best Air Purifiers]( BY BRENDA STOLYAR AND GEAR TEAM [Keep the wildfire smoke, smog, and allergens out. We tested standard and HEPA models to find the right one for your home.](   [bottles of wine]( [GRAPES OF WRATH | 6-MINUTE READ]( [Wine Is Getting Pricier Thanks to a Logistical Nightmare]( BY MATT SIMON [Supply chain issues, drought, and war are conspiring to make it way more expensive to produce the drink around the world.](   [A group of people at a long dining table]( [WIRED Q&A | 13-MINUTE READ]( [Rian Johnson Knows the Tech Bro in Glass Onion Looks Very Familiar]( BY ANGELA WATERCUTTER [When asked if he’d ever write a whodunit about the downfall of Twitter, the director joked, “Didn’t I just do that?”](   Looking for a new job? Check out these featured listings and search for openings all over the world on [jobs.wired.com](. [SQL Developer]( [Plaxonic Technologies]( Location: New York, USA [APPLY NOW]( [Sr. Financial Mgmt]( [Lockheed Martin Corporation]( [Location: Manassas, VA, USA]( [APPLY NOW]( [(image) WIRED Logo]( [(image) WIRED on Facebook]( [(image) WIRED on Twitter]( [(image) WIRED on Instagram]( [(image) WIRED on LinkedIn]( [(image) WIRED on YouTube]( [Podcasts]( Have questions or comments? [Reply to this email](mailto:hello@wired.com?subject=WIRED%20Newsletter%20Questions,%20Comments%20or%20Feedback). This email was sent to you by WIRED. To ensure delivery to your inbox (not bulk or junk folders), please add our email address, wired@newsletters.wired.com, to your address book. View our [Privacy Policy]( [Unsubscribe]( or [Manage your newsletter subscriptions](newsletter=wir) Copyright © Condé Nast 2022. One World Trade Center, New York, NY 10007. All rights reserved.

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