Hyderabad-based Biological E. Limitedâs Corbevax has been approved by the Drug Controller General of India (DCGI) as a heterologous COVID-19 booster dose for individuals aged 18 years and above, after 6 months of administration of primary vaccination (two doses) of Covaxin or Covishield vaccines. The company said that Corbevax is the first such vaccine in India to be approved as a heterologous COVID-19 booster. A heterologous booster is when the third dose is different from the earlier doses. ââRecently, BE furnished its clinical trials data to the DCGI, who after a detailed evaluation and deliberations with Subject Experts Committee, granted their approval for administering Corbevax vaccine as a heterologous booster dose to people who have already taken two doses of either Covishield or Covaxin,ââ a statement from BE said. The company also said that the clinical trial data showed that Corbevax booster dose provided significant enhancement in immune response and good safety profile required for an effective booster. As many as 100 million doses of Corbevax have been supplied by BE to the Government of India. Corbevax is entirely developed and manufactured by Biological E. Limited in association with Texas Childrenâs Hospital and Baylor College of Medicine as a recombinant protein sub-unit vaccine against COVID-19. Eight killed, 15 injured in boiler explosion at factory in Uttar Pradeshâs Hapur At least eight workers died and 15 were injured after a boiler exploded at a chemical factory in western Uttar Pradeshâs Hapur district, police said. The police also said there were 25 people in the affected area in the factory in the UPSIDC industrial area in Dholana, around 80 km from the national capital, when the incident occurred. While the impact of the explosion damaged the roofs of some of the factories located in the vicinity, it took three hours for the fire tenders to douse the blaze in the factory, located adjacent to a CNG pump. The relief and rescue measures continued at the site, officials said. Inspector-General of Police (Meerut range) Praveen Kumar said that eight persons lost their lives. Out of the 17 remaining people, 15 were hospitalised while the rest suffered minor injuries. Meanwhile, U.P. Chief Minister Yogi Adityanath expressed his condolences. âThe Chief Minister has directed district administration officers to go to the spot and oversee rescue and relief measures and extend all possible help to the victims and their families,â the CMâs office tweeted. I&B Ministry asks YouTube, Twitter to take down controversial deodorant advertisement The Information and Broadcasting Ministry asked YouTube and Twitter to remove videos of a derogatory deodorant advertisement, stating that it was detrimental to the portrayal of women. The Ministry sent emails to both the social media platforms, drawing their attention to the video uploaded earlier on Friday. It had garnered close to a million views on YouTube and was also circulated on Twitter. âThe above mentioned video is detrimental to the portrayal of women in the interest of decency or morality, and in violation of the rule 3(1)(b)(ii) of the Information Technology (Intermediary Guidelines and Digital Media Ethics Code) Rules, 2021, which inter-alia provides that the users shall not host, display, upload, modify, publish, transmit, store, update or share any information which is insulting or harassing on the basis of gender,â said the Ministry. The advertisement had also been broadcast on TV, prompting the Advertising Standards Council of India to direct the advertiser to suspend the advertisement immediately. Previously, the Delhi Commission for Women (DCW) wrote to the I&B Minister Anurag Thakur seeking action against the deodorant brand for the âmisogynistic advertisementâ that promoted âgang-rape culture.â The Commission also issued a notice to the Delhi Police to register a First Information Report and get the content removed from the mass media. Odisha Ministers resign en masse ahead of Cabinet reshuffle In Odisha, Ministers of the Naveen Patnaik government tendered their resignation en masse and the papers were forwarded to Governor Ganeshi Lal for his acceptance. The new set of Ministers is scheduled to take oath at the Raj Bhawan on Sunday. This is the first time all Ministers were asked to put in their papers at one go in the State. Speaker Surjya Narayan Patro also resigned from his post, which fuelled speculations that he might be taken in as a Minister in Sundayâs reshuffle. However, some Ministers are expected to be retained in the new cabinet. Senior leaders of the ruling Biju Janata Dal said that some MLAs had already received calls about their new assignment and were asked to remain present in Bhubaneswar. Notably, Chief Minister Naveen Patnaik is carrying out the Cabinet reshuffle for the first time in his fifth term. In Brief More than 800 people were booked, 24 arrested and 12 detained for questioning by the Uttar Pradesh police in connection with the riots and violence in Kanpur earlier on Friday. The accused would be booked under the National Security Act and the Gangster Act while the properties of those involved in the violence will be seized or demolished, according to the police. Further, the possible involvement of groups like Popular Front of India (PFI) and others is also being looked into. Evening Wrap will return tomorrow [logo] The Evening Wrap 04 JUNE 2022 [The Hindu logo] Welcome to the Evening Wrap newsletter, your guide to the day’s biggest stories with concise analysis from The Hindu. [[Arrow]Open in browser]( [[Mail icon]More newsletters]( Corbevax gets DCGI nod as COVID-19 booster after two doses of Covishield or Covaxin  Hyderabad-based Biological E. Limitedâs [Corbevax has been approved by the Drug Controller General of India (DCGI) as a heterologous COVID-19 booster dose]( for individuals aged 18 years and above, after 6 months of administration of primary vaccination (two doses) of Covaxin or Covishield vaccines. The company said that Corbevax is the first such vaccine in India to be approved as a heterologous COVID-19 booster. A heterologous booster is when the third dose is different from the earlier doses. [Corbevax is the first such vaccine in India to be approved as a heterologous COVID-19 booster, the vaccineâs maker Biological E. has said. File] ââRecently, BE furnished its clinical trials data to the DCGI, who after a detailed evaluation and deliberations with Subject Experts Committee, granted their approval for administering Corbevax vaccine as a heterologous booster dose to people who have already taken two doses of either Covishield or Covaxin,ââ a statement from BE said. The company also said that the clinical trial data showed that Corbevax booster dose provided significant enhancement in immune response and good safety profile required for an effective booster. As many as 100 million doses of Corbevax have been supplied by BE to the Government of India. Corbevax is entirely developed and manufactured by Biological E. Limited in association with Texas Childrenâs Hospital and Baylor College of Medicine as a recombinant protein sub-unit vaccine against COVID-19. Eight killed, 15 injured in boiler explosion at factory in Uttar Pradeshâs Hapur At least [eight workers died and 15 were injured after a boiler exploded at a chemical factory in western Uttar Pradeshâs Hapur district]( police said. The police also said there were 25 people in the affected area in the factory in the UPSIDC industrial area in Dholana, around 80 km from the national capital, when the incident occurred. While the impact of the explosion damaged the roofs of some of the factories located in the vicinity, it took three hours for the fire tenders to douse the blaze in the factory, located adjacent to a CNG pump. [Police at the site of a boiler explosion in the Western Uttar Pradesh district of Hapur on June 4, 2022. Photo: Twitter/@hapurpolice] The relief and rescue measures continued at the site, officials said. Inspector-General of Police (Meerut range) Praveen Kumar said that eight persons lost their lives. Out of the 17 remaining people, 15 were hospitalised while the rest suffered minor injuries. Meanwhile, U.P. Chief Minister Yogi Adityanath expressed his condolences. âThe Chief Minister has directed district administration officers to go to the spot and oversee rescue and relief measures and extend all possible help to the victims and their families,â the CMâs office tweeted. I&B Ministry asks YouTube, Twitter to take down controversial deodorant advertisement The Information and Broadcasting Ministry [asked YouTube and Twitter to remove videos of a derogatory deodorant advertisement]( stating that it was detrimental to the portrayal of women. The Ministry sent emails to both the social media platforms, drawing their attention to the video uploaded earlier on Friday. It had garnered close to a million views on YouTube and was also circulated on Twitter. âThe above mentioned video is detrimental to the portrayal of women in the interest of decency or morality, and in violation of the rule 3(1)(b)(ii) of the Information Technology (Intermediary Guidelines and Digital Media Ethics Code) Rules, 2021, which inter-alia provides that the users shall not host, display, upload, modify, publish, transmit, store, update or share any information which is insulting or harassing on the basis of gender,â said the Ministry. The advertisement had also been broadcast on TV, prompting the Advertising Standards Council of India to direct the advertiser to suspend the advertisement immediately. Previously, the Delhi Commission for Women (DCW) wrote to the I&B Minister Anurag Thakur seeking action against the deodorant brand for the âmisogynistic advertisementâ that promoted âgang-rape culture.â The Commission also issued a notice to the Delhi Police to register a First Information Report and get the content removed from the mass media. Odisha Ministers resign en masse ahead of Cabinet reshuffle In Odisha, [Ministers of the Naveen Patnaik government tendered their resignation en masse]( and the papers were forwarded to Governor Ganeshi Lal for his acceptance. The new set of Ministers is scheduled to take oath at the Raj Bhawan on Sunday. This is the first time all Ministers were asked to put in their papers at one go in the State. Speaker Surjya Narayan Patro also resigned from his post, which fuelled speculations that he might be taken in as a Minister in Sundayâs reshuffle. However, some Ministers are expected to be retained in the new cabinet. Senior leaders of the ruling Biju Janata Dal said that some MLAs had already received calls about their new assignment and were asked to remain present in Bhubaneswar. Notably, Chief Minister Naveen Patnaik is carrying out the Cabinet reshuffle for the first time in his fifth term. In Brief More than [800 people were booked, 24 arrested and 12 detained for questioning]( by the Uttar Pradesh police in connection with the riots and violence in Kanpur earlier on Friday. The accused would be booked under the National Security Act and the Gangster Act while the properties of those involved in the violence will be seized or demolished, according to the police. Further, the possible involvement of groups like Popular Front of India (PFI) and others is also being looked into. Evening Wrap will return tomorrow  Todayâs Top Picks [[French Open 2022 | Swiatek brushes aside Gauff to win second title] French Open 2022 | Swiatek brushes aside Gauff to win second title](
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