+ what happens when downtowns give parking back to the people US Edition - Today's top story: The FDA's big gamble on the new Alzheimer's drug [View in browser]( US Edition | 10 June 2021 [The Conversation](
Academic rigor, journalistic flair Patients and researchers often complain that the U.S. Food and Drug Administration takes too long to approve new drugs. So it might come as a surprise that a fast-tracked approval â in this case for a drug to treat Alzheimerâs disease â met pushback for being too speedy. But thatâs exactly what happened as the FDA gave a temporary green light to aducanumab following an accelerated approval process. The decision was made even though the FDAâs external advisory board urged the drugâs rejection last year because of a lack of data supporting its effectiveness. And at $56,000 a year, treatment with aducanumab will be very expensive, especially for Medicare. To better understand the controversy surrounding the FDAâs verdict, I asked pharmacist and drug development expert C. Michael White of the University of Connecticut to break down what accelerated approval entails. He also explained the benefits for patients â and [whether the drugs are worth their high cost](. Also today: - [What Aristotle and Kant thought about billionaires shrinking their tax bills](
- [How to teach children about slavery](
- [535 fast radio bursts may reveal deepest mysteries of the cosmos]( Vivian Lam Assistant Health and Medicine Editor
Do the benefits of approving a drug before confirming it works outweigh the potential costs? monkeybusinessimages/iStock via Getty Images Plus
[The FDAâs big gamble on the new Alzheimerâs drug]( C. Michael White, University of Connecticut The FDA approved Alzheimer's disease drug aducanumab despite minimal evidence of its efficacy. Whether this decision ultimately hurts or helps patients depends on data researchers don't yet have. Education -
[Hereâs what I tell teachers about how to teach young students about slavery]( Raphael E. Rogers, Clark University Few issues are as difficult to deal with in the classroom as slavery in the US. Here, a professor who trains teachers on how to present the topic offers some insights. Science + Technology -
[535 new fast radio bursts help answer deep questions about the universe and shed light on these mysterious cosmic events]( Emmanuel Fonseca, West Virginia University Fast radio bursts are the focus of a young and fascinating field of astronomy. Researchers just released data on more than 500 new bursts, quadrupling the total number of detected events. -
[Working with dangerous viruses sounds like trouble â but hereâs what scientists learn from studying pathogens in secure labs]( Jerry Malayer, Oklahoma State University Scientists get up close and personal with deadly pathogens to give doctors the tools they need to treat people sickened by germs. The key is keeping the researchers â and everyone around them â safe. Ethics + Religion -
[Is tax avoidance ethical? Asking on behalf of a few billionaire friends]( Erin Bass, University of Nebraska Omaha Wriggling out of paying taxes may be legal, but is it right? Aristotle, Immanuel Kant â and others â have their say. Environment + Energy -
[Parking reform could reenergize downtowns â hereâs what happened when Buffalo changed its zoning rules]( Daniel {NAME} Hess, University at Buffalo; Jeffrey Rehler, University at Buffalo When Buffalo, New York, changed its zoning code so that developers no longer had to provide specified amounts of parking, space was freed up for public transit and people. Health -
[Alcohol companies make $17.5 billion a year off of underage drinking, while prevention efforts are starved for cash]( David H. Jernigan, Boston University In the US, underage drinking accounts for a whopping $17.5 billion worth of alcohol yearly. New research shows which companies take in most of this money and how little is spent on prevention. Economy + Business -
[Women are as likely as men to accept a gender pay gap if they benefit from it]( Marlon Williams, University of Dayton An experimental study found that the vast majority of women didn't support a pay policy that corrected for an advantage they received, slightly more than men in the same position. -
[A new reason Americans are getting leery of billionaire donors]( David Campbell, Binghamton University, State University of New York News about how little income tax some of the richest Americans reportedly pay is adding to questions about the value to society of their massive charitable donations. -
[Senator Warrenâs wealth tax might prevent billionaires from paying nearly nothing in taxes â but itâs probably not constitutional]( Beverly Moran, Vanderbilt University A new report found that America's top billionaires paid very little income tax despite tremendous gains in their wealth. Trending on Site -
[A volcanic eruption 39 million years ago buried a forest in Peru â now the petrified trees are revealing South Americaâs primeval history]( Deborah Woodcock, Clark University; Herb Meyer, National Park Service Using remnants of fossilized trees, scientists and an artist figured out what the forest looked like long before humans existed. -
[When will the first baby be born in space?]( Chris Impey, University of Arizona In the coming decades, governments and private companies will set up permanent bases on the Moon and Mars. And at some point, the first galactic baby will be born. -
[How effective is the first shot of the Pfizer or Moderna vaccine?]( William Petri, University of Virginia The vaccine rollout is underway, but what happens if there is a supply disruption? Would it be feasible to change strategy and give more people a first dose? An expert analyzes the data. Youâre receiving this newsletter from [The Conversation](.
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