Brain Organoids: Emerging Tools for Neurological Disease Research

Created for {EMAIL} | [Web Version]( This is a paid advertisement. Live Science [Follow [LinkedIn]]( [Subscribe [YouTube]]( [Brain Organoids: Emerging Tools for Neurological Disease Research]( [Sino Biological]( [Featured Products]( [Featured Cytokines]( [CRO Services]( Neurodegenerative diseases are debilitating disorders characterized by deterioration of brain function, and affect millions of people worldwide. Currently, the most commonly used models of brain diseases involve postmortem human brain tissue, non-human primate tissue, or 2D in vitro experiments, but they are limited by resources and species differences in animal brains. 3D brain organoids developed from embryonic stem cells (ESCs) or induced pluripotent stem cells (iPSCs) have emerged as a promising model for studying neurodegenerative diseases. Organoids of various parts of the brain, such as forebrain, midbrain, and hippocampus, are cultured and utilized to study neurobiological and neurodevelopmental disorders in vitro. Cytokines play a critical role in brain organoid cultures. For example, [FGF2]( [EGF]( [Noggin/NOG]( and [BMP4]( have been used to direct cell differentiation along specific organ lineages. In addition, [FGF2]( [FGF19]( and [SDF1]( are employed for the cultivation of cerebellar organoids which are used to study spinocerebellar ataxia. [Sino Biological provides a wide range of cytokines for use in brain organoid culture to support research on neurodegenerative diseases.]( [Learn More]( Featured Cytokines for Brain Organoid Culture High Purity HPLC-verified High Activity Cited by Researchers Human EGF Protein, HPLC-verified Human FGF2 Protein Cat#: [10605-HNAE]( 16 Citations Cat#: [GMP-10014-HNAE]( Activity-validated: Cell proliferation assay using Balb/C 3T3 mouse embryonic fibroblasts. Activity-validated: Cell proliferation assay using Balb/c 3T3 mouse embryonic fibroblasts. Human BMP4 Protein Human Noggin/NOG Protein Cat#: [10609-HNAE2]( Cat#: [10267-HNAH]( HPLC-verified Activity-validated: Cell proliferation assay using NIH-3T3 mouse embryonic fibroblast cells. Activity-validated: Inhibit BMP4-induced alkaline phosphatase production by MC3T3E1 mouse preosteoblast cells. [More Cytokines for Brain Organoid Culture]( Featured Antibodies for Brain Organoid Research Anti-SOX2 Antibody Rabbit mAb Anti-beta-III Tubulin/TUBB3 Antibody Rabbit pAb Cat#: [100106-R017]( Applications: IHC-P Cat#: [101288-T34]( 1 Citation Applications: WB, ICC/IF Immunochemical staining of human SOX2 in human testis. Immunofluorescence staining of TUBB3 in hESC-H9 cells. [More Products Related to Brain Organoid Culture]( [A Comprehensive Collection of Recombinant Growth Factors for Organoid Culture | Click]( [Organoid Research Resources: Video, Infographic, Podcast, and More | Click]( [Sino Biological]( Sino Biological, Inc. (China) order@sinobiological.com Sino Biological US Inc. (U.S.A.) order_us@sinobiologicalus.com Sino Biological Europe GmbH (Europe) order_eu@sinobiologicaleu.com Sino Biological Japan Inc. (Japan) order@sinobiological.co.jp About this email: Future will occasionally send emails from our business partners promoting products and services likely to be of interest to our readers. [Unsubscribe]( | [Privacy Policy]( [Future]( Future US LLC © Full 7th Floor, 130 West 42nd Street, New York, NY, 10036