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[Therapeutic Targets for Alzheimerâs Disease: APP, Tau, BACE1, and More]( [Sino Biological]( [Featured Products]( [Featured Cytokines]( [CRO Services]( Alzheimer's disease (AD) is a complex neurological disorder that significantly impacts the aging population. Molecular biomarkers, including [APP]( [Tau]( [BACE1]( [ApoE]( [GLP1R]( [NGF]( [BDNF]( [GSK3B]( [CASP9]( [CLU]( [AGER]( [DPYSL2]( and [PNMT]( play pivotal roles in AD's pathological processes, offering potential targets for therapeutic interventions. The process from research to clinical success is challenging, marked by ongoing trials exploring novel Alzheimer's therapeutics targeting Aβ, tau, neuroinflammation, and synaptic preservation. Notably, FDA-approved anti-Aβ antibodies like aducanumab (Aduhelm®) and lecanemab (Leqembi®) have emerged. The research landscape relies on recombinant proteins such as Aβ, tau, GLP1R, and ApoE to drive drug discovery and mechanistic studies.
[Download Poster]( Alzheimer's Disease (AD) Pathogenesis
[Learn More]( [Sino Biological is at the forefront of Alzheimer's research, offering recombinant biomarkers and providing valuable insights to supporting drug discovery and novel therapeutics development.]( Featured Recombinant Proteins for AD Drug Targets HPLC-verified
Validated activity
Broad coverage of species and tags
Highly cited in reputable journals Human BACE1 Protein,
HPLC-verified Human GLP1R Protein,
HPLC-verified
Cat#: [10064-H08H]( Cat#: [13944-H49H-B]( High-purity:
⥠95 % as determined by SDS-PAGE &; SEC-HPLC. High-purity:
⥠95 % as determined by SDS-PAGE &; SEC-HPLC. Human GSK3B Protein,
Activity-validated Human NGF Protein,
Activity-validated
Cat#: [10044-H07B]( 4 Citations Cat#: [11050-HNAC]( 3 Citations Activity-validated:
Immobilized His-GSK3B can bind to biotinylated human HG3C-CTNNB1 (Cat#: [11279-H20B](. Activity-validated:
Cell proliferation assay using TF-1 human erythroleukemic cells. [More Recombinant AD Drug Targets](
Featured Antibodies Against AD Targets Anti-BACE1 Antibody,
Rabbit mAb Anti-ApoE Antibody,
Rabbit pAb
Cat#: [10064-R027](
Applications: FCM, ICC/IF Cat#: [10817-RP02](
Applications: ELISA, IHC-P Immunofluorescence staining of Human BACE1 in Hela cells. Immunochemical staining of human APOE in human liver. [More Antibodies Against AD Targets](
More Recommended AD Target Products Product Type Cat# Product Name
Recombinant Protein [11629-HCCH]( Human RAGE Protein (No Tag)
Recombinant Protein [10703-H02H]( Human APP Protein (hFc Tag)
Recombinant Protein [11297-H08H]( Human Clusterin Protein (His Tag)
Recombinant Protein [10058-H07E]( Human Tau Protein (His Tag)
Recombinant Protein [50240-M08H]( Mouse BDNF Protein (His Tag)
Antibody [10044-T32]( Anti-GSK3B Antibody, Rabbit pAb
Antibody [203068-T38]( Anti-DPYSL2 Antibody, Rabbit pAb
Antibody [11297-MM01]( Anti-Clusterin Antibody, Mouse mAb [Gain Valuable Insights for Developing Novel Alzheimerâs Therapeutics | Download](
[A Comprehensive Guide to Choosing High-quality Cytokines Based on Applications | Click]( [Sino Biological](
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