This may be the #1 oncology biotech company to watch closely in 2024 and beyond.âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ âÍ Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Greetings All, The oncology sector is home to some pretty big pharma beasts that include Amgen and Novartis. This arena got a big boost at the end of last month when Wall Street learned that AbbVie would be buying cancer drug developer Immunogen for a whopping $10 billion. While shares of ImmunoGen rallied 83% on the day of the announcement, other biotech companies also jumped on the news. The scramble to treat and potentially cure cancer has been on for decades and there is BIG money in this space. Cancer is devastating and solving it is lucrative. All this brings attention to a little-known company in the small-cap OTC market that has the potential to transform cancer treatment! Trading at SUB-PENNY prices, Propanc Biopharma, Inc. (OTC: PPCB) has a unique approach to treating metastatic cancer that could turn it into the next Biotech Darling! With executive leadership that has significant scientific, clinical, and operational experience, as well as a novel technology that has large-scale global potential, PPCB is an underfollowed oncology company that should be high on your radar! Who is PPCB? Propanc Biopharma is a clinical-stage biopharmaceutical company developing new cancer treatments for solid tumors. The company has developed a formulation of anti-cancer compounds designed to control or prevent tumors from recurring and spreading throughout the body by using proenzymes, which are inactive enzyme precursors. Enzyme therapy allows us to fight cancer, using natural elements already found within our organism. Enzymes are natural proteins that stimulate and accelerate biological reactions in the body. The enzymes that are secreted by the exocrine pancreas are essential for the digestion of proteins and fats. More than one hundred years ago, Professor John Beard first proposed that pancreatic enzymes represent the bodyâs primary defense against cancer and would be useful as a cancer treatment. Since then, several scientists have endorsed Beard´s hypothesis with encouraging data from patient treatment. PPCB intends to target patients with limited therapeutic options for the treatment of solid tumors, initially pancreatic, ovarian, or colorectal tumors. A Novel Therapy: PPCBâs novel proenzyme therapy is based on the science that enzymes stimulate biological reactions in the body, especially enzymes secreted by the pancreas. These pancreatic enzymes could represent the bodyâs primary defense against cancer! To view the Companyâs "Mechanism of Action" video on its anti-cancer lead product candidate, PRP, click here: [( Lead Candidate PRP: PRP controls cancer cell migration, inhibits tumor blood vessel formation, and triggers the cellâs death. Metastasis occurs because a program inside the cell called the Epithelial-Mesenchymal Transition (EMT) is activated, which causes epithelial cancer cells to become invasive and stem cell-like, allowing these cancer cells to spread and metastasize. The companyâs lead product, PRP, is a mixture of two proenzymes, trypsinogen and chymotrypsinogen from the bovine pancreas, administered by intravenous injection. - Mixture of 2 proenzymes from bovine pancreas.
- Synergistic ratio of 1:6 inhibits growth of most tumor cells, in vitro.
- Examples include ovarian and colorectal cancers.
- Efficacy also shown in pancreatic, kidney, breast, brain, prostate, lung, liver, uterine and skin cancers. - Achieved Orphan Drug Designation from the FDA for treating pancreatic cancer. Significant Market Opportunity for Cancer Therapy: 80% of all cancers are solid tumors and PPCB is initially targeting: - Pancreatic cancer â one of the hardest cancers to detect early - Ovarian cancer - the sixth most common cancer in the world - Colorectal tumors â a cancer that is quickly affecting younger people Big News: Last month PPCB announced that PRP enhances the sensitivity of resistant pancreatic tumor cells to standard chemotherapy treatment and alters the tumor microenvironment by decreasing the fibrotic tissue and its malignancy (ability to spread into surrounding tissues). The results were reported by the Companyâs joint researcher, Mrs. Belén Toledo Cutillas, MSc, at the laboratory of Professor Macarena Perán, PhD, University of Jaén, Granada, Spain. Dr Julian Kenyon, MD, MB, ChB, Propancâs Chief Scientific Officer said, "Results from the experiments conducted by Belen demonstrate the effects of PRP on reducing chemoresistance in pancreatic tumor cells, which is a significant issue among pancreatic adenocarcinoma (PDAC) patients, who have a poor 5-year survival rate of less than eight percent.â This could be a game-changer for pancreas cancer patients! First-In-Human Study: PPCB will target the Peter Mac Cancer Center in Melbourne, Australia, as the site for the First-In-Human (FIH) study for PRP in patients with advaAnced solid tumors. Initial discussion held previously with the Clinical Investigator confirmed the remaining development activities to be conducted by the Company prior to filing the clinical trial application for the FIH study. This includes the finished drug product manufacture and validation of the bioanalytical method to analyze the pharmacokinetics (movement of drug within the body) of PRP during the study. More Company Highlights: - 15 years of scientific research and clinical experience suggest PRP has the potential to convert cancerous cells back into normal cells.
- Strong pipeline with more than 60 products in clinical development.
- Maintains research partnerships with the University of Bath, University of Jaén, University of Granada, and the Foundation for Biosanitary Research of Andalusia Orients. The Bottom Line: Propanc Biopharma, Inc. (OTC: PPCB) could emerge as the next winner in the oncology space and is trading at under a penny currently! The company is developing its lead product, PRP, to treat early-stage cancer and pre-cancerous diseases and as a preventative measure for patients at risk of developing cancer, based on genetic screening. Why does the company stand out? Because there is NO effective standard treatments existing for solid tumors. Tumor cells return to the normal pathways of a differentiated cell. This gives the company a remarkable opportunity to capture a significant market. And remember, PPCB has already achieved Orphan Drug Designation from the FDA for treating pancreatic cancer. "Despite facing significant global challenges in recent years as a micro-cap company, we face the future heading into the new financial year with growing optimism. We expect to enter clinical development stage with PRP, which management believes will identify a new therapeutic approach to the treatment and prevention of metastatic cancer, which remains the main cause of patient death for sufferers. PRP does not exhibit the same severe or even serious side effects compared to standard.â â CEO James Nathanielsz PPCBâs groundbreaking science could mean an exciting 2024 so keep your eyes on the company! Copyright 2023 © SCDalerts.com is owned and operated by the owner of SCD Media LLC. Disclaimer and Privacy For more Information please contact info@smallcapsdaily.com This website provides information about the stock market and other investments. This website does not provide investment advice and should not be used as a replacement for investment advice from a qualified professional. 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