ð¨Trade Alert ð¨ BCTXÍ â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â Í â This little-known biotech company has a âSTRONG BUYâ rating from NASDAQ and a $25 price target! Greetings All, Any investor interested in the science scene should take a close look at the oncology arena on Wall Street. Coming in only after cardiovascular disease, cancer is the second leading cause of death in this world. Precedence Research projects that the global oncology market will increase at a compound annual growth rate of 8.2 percent to reach [US$581.25 billion in 2030!]( Itâs no surprise that oncology has become one of the biggest sectors as biotech and pharma companies scurry to develop best-in-class therapeutics to help treat the disease. There is a revolution happening in cancer therapy as cancer is killing millions of people annually. One quietly trading NASDAQ company could be trading at a supreme value right now and should be high on your radar! The company is developing targeted and effective approaches for the management of cancer. BriaCell Therapeutics Corp. (NASDAQ: BCTX) is an immune-oncology-focused biotech that could quickly capture Wall Streetâs attention as it [carries a massive $25 price target on it!]( Currently, shares are trading at around $7. At a $25 price target, BCTX could stand to see 247% upside!It also screams in volumes that insiders were net buyers in the company during the past 12 months. The biggest single purchase by an insider was when Independent Chairman of the Board Jamieson Bondarenko bought CA$174k worth of shares at a price of CA$6.23 per share. And want another good reason why BCTX should have your immediate attention? [BriaCell recently announced Positive End of Phase II Meeting with the FDA for BriaCellâs lead candidate, Bria-IMT⢠Combination in Advanced Metastatic Breast Cancer!]( [Fast Track status by the U.S. Food and Drug Administration (FDA)]( Bria-IMTâ¢, is being evaluated in a [Phase II]( randomized clinical trial in advanced metastatic breast cancer (i.e. breast cancer that has spread beyond the breast to other tissues). Our immunotherapy boosts the ability of the body's own cancer fighting cells to find and destroy cancerous tumors!Both Bria-IMT⢠and Bria-OTS⢠are two promising drugs under development in the fight against breast cancer and Bria-IMT⢠has shown remarkable results thus far in clinical trials. With a green light from the FDA for Fast Track Status, BCTX is surely a biotech company to put on your watch list as the company progresses towards a pivotal study initiation for Bria-IMT in combination with an immune checkpoint inhibitor in advanced metastatic breast cancer. BCTX may be one of the hottest biotech stories unfolding as it currently carries âSTRONG BUYâ ratings from BarChart.com, Investing.com, and NASDAQ.com! [( NASDAQ: BCTX Developing Novel Therapies to Destroy Cancer Focusing initially on breast cancer, BriaCell Therapeutics Corp. (Nasdaq: BCTX) is dedicated to enhancing the lives of people with cancer with limited therapy options by developing novel immunotherapies to fight cancer. Immunotherapies have become the forefront of cancer treatments because they use the bodyâs immune system to destroy cancer cells, offer the potential for higher levels of safety and efficacy than chemotherapy, and may also prevent cancer recurrence. A Collaboration with Incyte Corporation: BCTX currently has a non-exclusive clinical trial collaboration with Incyte Corporation (Nasdaq: INCY) to evaluate the effects of combinations of novel clinical candidates. Under the agreement, Incyte and BriaCell will evaluate novel combinations of compounds from Incyteâs development portfolio with BriaCellâs drug candidates in advanced breast cancer patients. Small Molecule Program BriaCellâs small molecule program consists of novel selective protein kinase C delta inhibitors that have shown activity in pre-clinical models of several cancers and fibrotic diseases. To reiterate⦠recently announced a positive end of Phase II meeting with the FDA for Bria-IM⢠combination in Advanced Metastatic Breast Cancer]( Following a successful completion of a Phase I study showing a favorable safety profile for the combination regimen, BriaCell is conducting a Phase II clinical trial of BriaCellâs lead candidate, Bria-IMTâ¢, awarded Fast Track status by the U.S. Food and Drug Administration (FDA), in combination with retifanlimab (INCMGA00012), an anti-PD-1 antibody (provided by Incyte). The combination study is listed on ClinicalTrials.gov as [NCT03328026](. Bria-OTSâ¢*: Recently awarded a patent by the USPTO, BriaCell is developing Bria-OTSâ¢, the first âoff-the-shelfâ personalized immunotherapy for the treatment for advanced stage breast cancer. In November 2020, BCTX announced a Cooperative Research and Development Agreement with the National Cancer Institute (NCI, Center for Cancer Research), part of the National Institutes of Health, to investigate the mechanism of action of novel off-the-shelf personalized therapeutics for cancer. BREAST CANCER: FACTS & STATISTICS - According to a report published by the American Cancer Society in 2023, approximately 609,820 Americans are expected to die from cancer in 2023 (approximately 1,670 deaths per day), making cancer the second leading cause of death in the U.S., exceeded only by heart disease.
- As of January 2023, the number of women in the U.S. with a history of invasive breast cancer is estimated to be 3.1 million (excluding the estimated 284,200 new cases in 2023). This number is expected to increase by 12% to 4 million in 2024. Approximately 30% of breast cancers occur in women younger than age 50 and 44% occur in women older than age 65. - According to an American Cancer Society in 2023 fact sheet, 297,790 women and 2,800 men are expected to be diagnosed with invasive breast cancer in 2023 in the U.S. alone. Breast cancer is the most frequently-diagnosed cancer in women in the U.S. - Breast cancer deaths in 2023 are estimated to be 43,700 (43,170 women, 530 men), making breast cancer the second leading cause of cancer death in women (after lung cancer). - As reported by the American Cancer Society in 2023, approximately 62% of breast cancer cases are detected at the early stages (i.e., the cancer is found in the breast tissue, and has not spread to lymph nodes or other regions of the body), for which the 5-year survival rate is estimated to be 99%. As soon as the cancer spreads to lymph nodes under the arm or nearby tissues (regional stage), the 5-year survival rate drops to 85%. However, once the cancer spreads to other lymph nodes or body parts (distant stage or metastatic cancer), the 5-year survival rate falls to as low as 27% (i.e. 73% of the patients die within 5 years). This shows the significant need for effective treatments for this deadly cancer. [SOURCE]( A SPIN OFFBCTXâs Board of Directors has unanimously approved a potential reorganization that would result in the spin-out of certain pre-clinical pipeline assets of the Company, specifically Bria-TILsRxâ¢, and PKCδ inhibitors for multiple indications including cancer (collectively, the âSpinCo Assetsâ) to an unlisted corporation to own the SpinCo Assets (âSpinCoâ). On closing of the Transaction, it is anticipated that the SpinCo Assets will be majority-owned, controlled, and governed by BriaCell and owned by BriaCell shareholders of record who will receive SpinCo Shares as defined herein.Dr. William V. Williams, BCTX President and CEO stated, âDeveloping them under a separate entity allows us to unlock the development potential of the SpinCo Assets as novel treatments for multiple diseases under a separate balance sheet, allowing for maximizing both entities to maintain their focus, while providing our shareholders the opportunity to own shares in both companies.â About the SpinCo Assets PKCδ Inhibitor: Therapeutics for multiple disease indications including cancer PKCδ, also called novel PKC, [has been associated]( with a number of diseases including cancer. Selective inhibitors of PKCδ, have been shown to be effective treatments for several animal models of [cancer]( and other diseases. SpinCoâs novel and highly selective PKCδ inhibitors may be developed as candidates for multiple disease indications including several tumor types. Bria-TILsRxâ¢: Multi-Specific Binding Reagents - Immunotherapies for Cancer Developed as potential immunotherapies for cancer, SpinCoâs two novel Bria-TILsRxâ¢s are multi-specific binding reagents designed to act as potent immune cell activators and/or immune checkpoint inhibitors. They are expected to selectively target and destroy cancer cells without harming normal (non-cancerous) cells. This may mean less severe side effects for the treated cancer patients compared with those of alternative therapies. In Summary⦠Itâs obvious that BCTX has a lot of exciting things going on. One of the biggest developments that could serve as a catalyst for gains dependent upon any positive news is the companyâs upcoming pivotal clinical study! BriaCell and the FDA have agreed on the primary end point, the essential elements of the study design, and the type of patients to be enrolled in BriaCellâs upcoming pivotal clinical study. This pivotal registration study will be enrolling advanced metastatic breast cancer patients for whom no approved treatment options exist. Registration study success could lead to a Biologics License Application (BLA) submission for the approval of the combination regimen for commercialization in advanced metastatic breast cancer. âThe importance of this milestone speaks for itself and is yet another major step towards our goal to become one of the leading immuno-oncology companies. Jumping directly into a pivotal study shortly after receiving Fast Track status has greatly advanced our lead clinical program timetable with the ultimate goal of commercializing our novel immunotherapy approach for women with no approved treatment options.â - Dr. William V. Williams, BriaCellâs President and CEO. Insiders are buying⦠âSTRONG BUYâ ratings are piling up⦠and a $25 price target indicates potential upside of over 200%! Now is the time to have BCTX on your radar! 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