Could this make your dog live longer?
November 29, 2023 [View Online]( | [Sign Up]( | [Shop]( [Morning Brew]( PRESENTED BY [LMNT]( Good morning. Mark Cuban just showed everyone why heâs the shark with the sharpest teeth. The Cubes is selling his majority stake in the NBAâs Dallas Mavericks to the casino tycoon Adelson family at a valuation of around $3.5 billionâwhile maintaining full control of basketball operations, per Shams Charania of The Athletic. In 2000, Cuban purchased the team for $285 million. Pair his Mavericks sale with recent news that Cuban is leaving Shark Tank after next season, and you might be thinking: âHeâs running.â Well, prediction markets currently put a presidential campaign at 25%. âMatty Merritt, Cassandra Cassidy, Sam Klebanov, Molly Liebergall, Adam Epstein, Neal Freyman MARKETS Nasdaq 14,281.76 +0.29% S&P 4,554.89 +0.10% Dow 35,416.98 +0.24% 10-Year 4.330% -6.1 bps Bitcoin $38,014.49 +2.06% PDD $139.00 +18.08% *Stock data as of market close, cryptocurrency data as of 1:00am ET. [Here's what these numbers mean.]( - Markets: Stocks regained their November momentum, [ticking up]( due toâstop us if youâve heard this beforeârenewed optimism that the Fed is done raising interest rates. The dayâs big winner was Temu parent company PDD Holdings, which surged 18% after the Chinese e-commerce platform [demolished]( revenue forecasts. Â Markets Sponsored by Autonomix Little chip, Big Apple: They created a microchip that maps the nervous system. [Invest in Autonomix before their Nasdaq listing goes live in Times Square](. HEALTHCARE [Yes, weâre talking about Obamacare again](
[Donald Trump]( Saul Loeb/AFP via Getty Images The only thing more recycled than your containers from the Thai restaurant closest to your apartment is former President Trumpâs most recent campaign promise. The 2024 Republican front-runner [posted]( on Truth Social this weekend that he is âseriously looking at alternativesâ for the Affordable Care Act (ACA), aka Obamacare, should he become president again. Trump added that failing to repeal Obamacare in his first term was âa low point for the Republican party, but we should never give up!â Obamacare? Havenât heard that name in years⦠Probably because most members of the Republican party, which vehemently opposed it since it was first enacted in 2010, pretty much gave up on fighting it years ago. In 2016 and 2017, numerous attempts to ârepeal and replaceâ the landmark healthcare bill were vetoed by former President Barack Obama or blocked by Democrats (and their few Republican allies) in Congress. In 2021, the Supreme Court threw out a lawsuit brought by 18 Republican state attorneys general and the Trump administration that would have gutted the ACA. This isnât the first time Trump [promised]( to ditch the ACA and bring a better health plan to the table: It was a big part of his 2016 platform. But said better health plan never materialized. Why have so many Republicansâother than Trumpâgiven up on axing it? Turns out, most Americans like it. - Six out of 10 Americans have a favorable opinion of Obamacare, according to a May 2023 KFF poll.
- Obamacareâs protections for people with preexisting conditions are especially popular: In 2020, 79% of Americans and even 66% of Republicans said they didnât want the Supreme Court to get rid of them. Elsewhere in the healthcare debate: Senators Elizabeth Warren (Democrat) and Mike Braun (Republican) [sent]( a letter to the US Department of Health and Human Services last week, asking it to investigate whether large insurance companies are hiking prescription drug prices at pharmacies they own.âMM Â Â PRESENTED BY LMNT [Heat up your hydration game](
[LMNT]( Whether youâre snuggling up after shoveling the driveway or refueling between runs down the ski slopes, winter activities require their very own hydration. Enter LMNTâs tasty electrolyte drink mixâ¦now hot. Itâs designed to be enjoyed piping hot in delish flavors like [Chocolate Mint, Chocolate Chai, and Chocolate Raspberry](. When the weather outside is frightful, hydrating needs to be especially delightful. From adding it to your morning coffee to enjoying a post-snowboarding pick-me-up, [savor LMNT]( on its own or add it to your fave drink recipes for an extra kick of electrolytes. Morning Brew readers even get [an exclusive LMNT gift with their purchaseâcheck it out]( and happy hydrating. WORLD [Tour de headlines](#)
[Charlie Munger]Johannes Eisele/Getty Images Charlie Munger died at 99. The investing guru and right hand to Warren Buffett at Berkshire Hathaway died in a California hospital on Tuesday, according to a company statement. Independent of being Berkshire Hathawayâs vice chairman, Munger was a [rockstar investor]( who served as CEO of Wesco Capital until 2011, when Berkshire took over control of the company. Together, Buffett and Munger catapulted Berkshire to 20.1% annual gainsâtwice the rate of the S&P 500âwith their innovative investing philosophies. As of this year, Mungerâs net worth was $2.5 billion. âBerkshire Hathaway could not have been built to its present status without Charlieâs inspiration, wisdom, and participation,â Buffett said in a statement. Koch network backs Nikki Haley in GOP primary. Billionaire Charles Kochâs political network, Americans for Prosperity Action, [endorsed]( former South Carolina Governor Nikki Haley for the 2024 presidential election in an attempt to consolidate resources around a candidate other than Trump. The groupâs support includes access to its $70 million fund for political races. The endorsement for Haley is a blow to Florida Governor Ron DeSantis, whoâs been jockeying to be seen as the partyâs Trump alternative. Several well-endowed donors, however, have pinned Haley as the strongest contender to go up against President Joe Biden. Consumer confidence rose for the first time in four months. The Conference Boardâs index rose from 99.1 in October to 102 in November thanks to [US consumersâ optimism]( around short-term income, hiring prospects, and the slowdown in inflation. The perceived likelihood of a recession also fell to the lowest level of 2023âthough two-thirds of Americans still think one is either âsomewhatâ or âvery likelyâ to happen in the next year. The improved economic outlook comes after [home prices]( rose to a new record in September, even as mortgage rates remained elevated. AI [Sports Illustratedâs AI snafu](
[Screenshot of a supposed fake writerâs profile on Sports Illustrated]( Francis Scialabba After Sports Illustrated reportedly published articles by seemingly nonexistent writers, the once-admired media darling is struggling to recover whatâs left of its image. On Monday, a [report]( by Futurism revealed that some SI contributorsâ profiles used AI-generated headshots, while a number of articles featured writing that sounded more robot than human. Sports Illustrated issued a [statement]( saying the pieces in question came from a third-party partner that assured SI the content was written by humansâ¦but thatâs up for debate. - One of the [articles]( âwrittenâ by âDrew Ortiz,â said, âVolleyball can be a little tricky to get into, especially without a ball to practice with.â
- Anonymous sources told Futurism that the content is âabsolutely AI-generated, no matter how much they say that itâs not.â SI has since added disclaimers to the articles from third parties that itâs published, but the damage to what had arguably been sports mediaâs most reputable legacy property is done. Current and former (human) journalists at SI have expressed [disappointment]( with the Arena Group, the company that now owns the SI brand and [has a history]( of using AI to generate stories. The debacle is yet another example of the perils of AI use in media. In August, Gannett [reneged]( on its AI local sports writing effort after a comically bad story went [viral]( it came under fire again in October following claims that one of its websites, Reviewed, published reviews written by AI.âCC Â Â TOGETHER WITH THE RAD
[The RAD]( The money masters have spoken. Find out how economic downturns are opportunities in disguise by reading the Wall Street Journal bestseller [Money Shackles](. Learn how to break free from the established system, create a positive relationship with money, and build wealth your way. [Download the first chapter for free](. SCIENCE [A startup is trying to make dogs live longer](
[Dog life-extension medicine]( Francis Scialabba Canine longevity startup Loyal got closer to its goal of helping our four-legged friends have more time to cuddle with us and terrorize squirrels. The Food and Drug Administration, which approves and regulates drugs for animals in addition to humans, said that Loyalâs life-extending drug for big dogs could reasonably [be expected to work]( based on early tests, the company announced (and the New York Times confirmed) yesterday. The regulatorâs nod paves the way for a large clinical trial to start and for the drug to appear at a vetâs office near you by 2026 following an expedited approval process for experimental animal meds. How it works The injectable prescription, LOY-001, is meant for large-breed canines with shorter lifespans than their lap-dog counterparts. While itâs no elixir of eternal puppyhood⦠- According to Loyal, LOY-001 curbs the production of a hormone called IGF-1 (big dogs have more of it). Blocking it in rodents and worms is already known to boost their life expectancy.
- Tests suggest that the drug might slow dog aging, but Loyal has yet to prove that LOY-001 does, in fact, extend their longevity. Though side effects appear minimal, some large-dog breeders worry about the ethics of giving healthy dogs a new drug that isnât proven to be effective. Could it work on humans? IGF-1 levels can affect human lifespan as well, but testing drugs on us two-legged folks is infinitely more complex.âSK Â Â GRAB BAG [Key performance indicators](#)
[Dolly Parton performing]NFL/CBS Stat: Maybe Jolene is the one who needs to worry. Just days after dressing as a Dallas Cowboys cheerleader during her halftime performance for the NFL teamâs Thanksgiving Day game, 77-year-old Dolly Parton hit a major milestone. Her album Rockstar, which debuted earlier this month, opened in the No. 3 spot on the Billboard 200 chartâmaking it her [highest-charting album ever](. Rockstar sold 118,500 copies in the week ending Nov. 23, marking the country legendâs [biggest sales week]( since electronic tracking began in 1991. In typical Dolly fashion, she took no credit, attributing the renaissance to her fans. Quote: âThere is one thing glaringly missing from this... soul.â That was one X userâs reaction to âBetrayed By This Town,â a song by AI singer-songwriter Anna Indiana that [went viral]( this week. Every aspect of the songâfrom the melody to the chord structure to the lyricsâwas generated with artificial intelligence. The reaction was overwhelmingly negative: The very human singer-songwriter James Blake sarcastically commented that the song brought him to tears. Undeterred, Indiana proceeded to release another song, saying her goal is to create a [24/7 livestream]( of AI music. Read: Everybody knows Flo from Progressive. Who is Stephanie Courtney? ([New York Times]( NEWS [What else is brewing](#) - [Googleâs]( first-of-its-kind geothermal power plant is now up and running in Nevada.
- [The presidents]( of Harvard, MIT, and Penn will appear before Congress next week to address antisemitism on their campuses.
- [Virgin Atlantic]( flew the first transatlantic commercial flight using 100% sustainable fuel, from London to New York.
- [Rupert Murdoch]( was deposed yesterday as part of Smartmaticâs $2.7 billion defamation lawsuit against Fox News.
- [The 41 trapped construction workers]( in India are finally free after surviving in a collapsed Himalayan road tunnel for more than two weeks. RECS
[Wednesday to-do list] Watch: Youâve never seen âAfricaâ by Toto played on a piano [like this](. Thaw: The [best socks]( for people with cold feet. Gaze: View a live sunset somewhere in the world, at any time of the day, with [Eternal Sunset](. Embrace nostalgia: Celebrate the 40th birthday of Now Thatâs What I Call Music with these [40 wild facts]( about the fabled compilation album. Learn: Level up your skills and advance your career with more than 100 hours of business education in our brand-new learning option. [Buy now in our exclusive presale]( to get $200 off. âSupersizeâ your bedroom adventures. Become the Superman of satisfaction with the [Tenuto 2](. Four motors deliver electrifying sensations from you to your partnerâwhile giving you a heroic erection. [Get 35% off]( *A message from our sponsor. GAMES [The puzzle section](#) Word Search: Famous monuments get the ice sculpture treatment in todayâs Word Search. Grab a pair of mittens and [play it here](. LeBrongevity trivia On Monday night, 38-year-old LeBron James passed Kareem Abdul-Jabbar as the NBAâs all-time leader in minutes played (regular season + playoffs). LeBron is in his 21st season. Take an educated guess at how many minutes LeBron has spent on an NBA court throughout his career. For reference: An NBA game is 48 minutes long. Give yourself full credit if you get within 5,000 minutes. SHARE THE BREW [Share Morning Brew]( with your friends, acquire free Brew swag, and then acquire more friends as a result of your fresh Brew swag. Weâre saying weâll give you free stuff and more friends if you share a link. One link. Your referral count: 0 [Click to Share]( Or copy & paste your referral link to others:
[morningbrew.com/daily/r/?kid=4904f90a]( ANSWER 66,319 Word of the Day Todayâs Word of the Day is: snafu, meaning âa situation marked by errors or confusion.â Interestingly enough, it was originally a military acronym for âsituation normal: all f****** up.â Thanks to Sue from Ohio and many others for the orderly suggestion. Submit another [Word of the Day here](. â· A Note From Autonomix This is a paid advertisement for Autonomixâs Regulation A+ Offering. Please read the offering circular at [invest.autonomix.com/](. Written by [Adam Epstein]( [Neal Freyman]( [Matty Merritt]( [Cassandra Cassidy]( Sam Klebanov, and [Molly Liebergall]( Was this email forwarded to you? Sign up [here](. Interested in podcasts? - Check out ours [here]( [ADVERTISE]( // [CAREERS]( // [SHOP]( // [FAQ]( Update your email preferences or unsubscribe [here](.
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