It'll never lead you astray. It'll never lead you astray. Dr. Anil Bajnath reveals the connection between your brain and your gut. You are receiving this email because you subscribed to Longevity Insider HQ.
[Click here]( to manage your e-mail preferences.
[Longevity Insider HQ logo] Want Stronger Brain Health? Go With Your Gut! – Part 1 Anil Bajnath, MD | August 31, 2021 | Baltimore, MD Dear Longevity Insider, The gut-brain axis is a term that refers to the two-way communication system between the gastrointestinal tract and the central nervous system. The gut-brain axis can be disrupted by many different factors, including stress. With an unhealthy gut microbiome (bacteria) in your digestive tract, you are more susceptible to many health conditions. These include inflammation, metabolic syndrome, obesity, type 2 diabetes, depression or anxiety disorders, and neurodegenerative diseases such as Alzheimer’s disease or Parkinson’s disease. This week, we'll explore how a healthy diet can help heal your gut microbiome by providing proper nourishment for good bacteria, while helping to remove bad bacteria from your body through natural detoxification pathways. WHAT IS THE GUT-BRAIN AXIS? The gut-brain axis has recently been coined as the new "Central Nervous System," which is a complex system of communication between the enteric nervous system in the gut and the central nervous system (CNS) in your brain. The gut-brain axis is responsible for maintaining homeostasis between the autonomic nervous system and the immune system, regulating substances that may act as neurotransmitters. When the gut-brain axis is not functioning optimally, this can lead to a range of problems including depression, anxiety, and stress-related disorders. Gut bacteria are responsible for maintaining the gut-brain axis by producing neurotransmitters that can stimulate specific cells in the gut which can then send signals back to the brain through various neurological pathways. [Strong evidence suggests that gut microbiota has an important role in bidirectional interactions between the gut and the nervous system. It interacts with the CNS by regulating brain chemistry and influencing neuro-endocrine systems associated with stress response, anxiety, and memory function.]( Gut microbiota can also influence brain function through the hypothalamic-pituitary-adrenal axis and autonomic nervous system. The hypothalamic-pituitary-adrenal axis is the major neuroendocrine system that mediates the stress response. Our autonomic nervous system is made up of the sympathetic nervous system (SNS), which is activated by stress and can stimulate colonic relaxation, vasoconstriction, and ileocaecal transit. Gut microbiota also interacts with immune cells in the gut, and these interactions have been shown to affect brain function. This has implications for mood disorders such as anxiety and depression that we will discuss later in this blog. Gut microbiota can also influence brain function through the autonomic nervous system, which regulates all of our unconscious actions (our heart rate, breathing pattern, etc). Another factor worth mentioning is neurotransmitters. Neurotransmitters are essentially electrical signals in the brain that help us communicate and regulate many bodily functions including mood, emotions, the ability to handle stress, and more. When our gut-health axis is off, our neurotransmitter signals can be disrupted, which causes a cascade of brain issues. To make this simple, we are going to focus on serotonin as an example of what our gut-health axis can do for us. Serotonin is a neurotransmitter that regulates mood and behavior. When serotonin levels get messed up, it not only causes anxiety but also disrupts sleep patterns and more. We'll take a closer look at the strong relationship bewteen the gut and mental health on Thursday. Meanwhile, take the time to assess your mood and how you feel. Have you been feeling, tired, fat, and sick? [It's probably because of this.]( To your longevity, Anil Bajnath MD
CEO/Founder, Institute for Human Optimization
Chief Medical Officer, Longevity Insider HQ --------------------------------------------------------------- This email was sent to {EMAIL}. It is not our intention to send email to anyone who doesn't want it. If you're not sure why you've received this e-letter, or no longer wish to receive it, you may [unsubscribe here](, and view our privacy policy and information on how to manage your subscription. To ensure that you receive future issues of Longevity Insider HQ, please add customerservice@abmdhealth.com to your address book or whitelist within your spam settings. For customer service questions or issues, please contact us for assistance. Longevity Insider HQ, Copyright © 2021. All rights reserved. 3 E. Read Street, Baltimore, MD 21202. For customer service, call (844) 491-5756. The content of this site may not be redistributed without the express written consent of Longevity Insider HQ. Individual editorials, articles and essays appearing on this site may be republished, but only with full attribution of both the author and Longevity Insider HQ as well as a link the website. None of these statements have been approved by the FDA to diagnose or treat any disease. Always consult with a trusted medical professional before starting or changing a health regimen. [Full Disclaimer](