Epigenetic Alterations: Change Is Inevitable – Part 2

And what you can do starting today. And what you can do starting today. Dr. Anil Bajnath explains how the best line of defense still points back to one thing. You are receiving this email because you subscribed to Longevity Insider HQ. [Click here]( to manage your e-mail preferences. [Longevity Insider HQ logo] Epigenetic Alterations: Change Is Inevitable – Part 2 Anil Bajnath, MD | March 11, 2021 | Baltimore, MD Dear Longevity Insider, Let's talk about our genetic volume control... Another change that has been observed as an epigenetic alteration is modification of histones. Remember the histone proteins and chromatin formation we mentioned on Tuesday? Histones are not only one of the primary components of the chromatin but are also integral in the regulation of gene expression. They can alter how tightly or loosely the DNA is wound around them – the looser they are, the more the genes expressed; the tighter they are, the less genes expressed – similar to how a knob would control volume. Abnormal modifications of histones have been correlated with various diseases, including cancer, autoimmune disorders, inflammation and neurological conditions. Our structural integrity A third change that is characteristic of epigenetic alteration is chromatin remodeling. The chromatin’s tight coiling structure condenses and protects our DNA. It also prevents DNA from being transcribed continuously. However, in order for genes to be accessed and expressed, they must ‘open’ in a process known as chromatin remodeling. This is crucial for proper cell functioning. In aging cells, enzymes that are involved in the DNA methylation and histone modification processes start to fade. This results in loss of integrity within the chromatin. Since the strength of the chromatin is necessary for DNA replication and repair, it becomes apparent that deterioration of this important structure can adversely affect the aging process. When the chromatin remodeling process starts to decline, epigenetic abnormalities accumulate, which can result in diseases such as cancer. Food is medicine In my best-selling book, The Longevity Equation, I indicate, “Research shows that epigenetic alterations can be slowed down by including plenty of bioactive compounds in your diet. You can do this by consuming healthy fruits, vegetables, seeds, nuts, and oils.” There is also research that these bioactive compounds alter DNA methylation and histone modifications and have the ability to favorably alter gene expression and prevent tumorigenesis. Foods particularly effective include turmeric, soybean, green tea, grapes, and cruciferous vegetables, such as broccoli and cauliflower. The authors state, “The emerging field of nutritional genomics targets nutrient-related genetic and epigenetic changes for prevention and therapy of various diseases including cancer.” Also, there's another food that I swear by... This plant has more than 48 of nature’s most powerful antioxidants, 36 health-promoting compounds, and a full spectrum of 18 amino acids and 11 vitamins and minerals. I've known about this green plant since I was just a kid. Fast-forward to today. The science world is just learning this plant’s potent benefits. And more than 1,300 studies have confirmed that this amazing plant could be the real-life “Fountain of Youth.” That's because it’s been shown to: - Skyrocket the production of immune cells by 60%! - Reduce the amount and depth of wrinkles by 233%. - Help increase your body’s natural insulin production by 74%. And that’s just the beginning of it… [There’s more you should know.]( To your longevity, Anil Bajnath MD CEO/Founder, Institute for Human Optimization Chief Medical Officer, Longevity Insider HQ --------------------------------------------------------------- This email was sent to {EMAIL}. It is not our intention to send email to anyone who doesn't want it. If you're not sure why you've received this e-letter, or no longer wish to receive it, you may [unsubscribe here](, and view our privacy policy and information on how to manage your subscription. To ensure that you receive future issues of Longevity Insider HQ, please add newsletter@longevityinsiderhq.com to your address book or whitelist within your spam settings. For customer service questions or issues, please contact us for assistance. Longevity Insider HQ, Copyright © 2021. All rights reserved. 3 E. Read Street, Baltimore, MD 21202. For customer service, call (844) 491-5756. The content of this site may not be redistributed without the express written consent of Longevity Insider HQ. Individual editorials, articles and essays appearing on this site may be republished, but only with full attribution of both the author and Longevity Insider HQ as well as a link the website. None of these statements have been approved by the FDA to diagnose or treat any disease. Always consult with a trusted medical professional before starting or changing a health regimen. [Full Disclaimer](