PNAS Table of Contents for 23 May 2017; Vol. 114, No. 21

[PNAS][Proceedings of the National Academy of Sciences] /content/current/content/multimedia/site/authors/index.xhtml/site/aboutpnas/index.xhtml/site/misc/collectedpapers.xhtml/search/content/early/recent [Submit using a single PDF, saving you time and effort.](/cgi/adclick/?ad=51171&adclick=true&url=http%3A%2F%2Fwww.pnas.org%2Fsite%2Fauthors%2Findex.xhtml) [Proceedings of the National Academy of Sciences](?etoc) [23 May 2017; Vol. 114, No. 21]( ) This Week in PNAS [In This Issue]( --------------------------------------------------------------- Letters (Online Only) [Further evidence for localized, short-term anthropogenic forest alterations across pre-Columbian Amazonia]( Dolores R. Piperno, Crystal McMichael, and Mark B. Bush [Reply to Piperno et al.: It is too soon to argue for localized, short-term human impacts in interfluvial Amazonia]( Jennifer Watling, José Iriarte, Francis E. Mayle, Denise Schaan, Luiz C. R. Pessenda, Neil J. Loader, F. Alayne Street-Perrott, Ruth E. Dickau, Antonia Damasceno, and Alceu Ranzi [Fast folding and slow unfolding of a resurrected Precambrian protein]( Adela M. Candel, M. Luisa Romero-Romero, Gloria Gamiz-Arco, Beatriz Ibarra-Molero, and Jose M. Sanchez-Ruiz [Reply to Candel et al.: Evidence for evolutionary conservation of folding kinetics in the thioredoxin protein family]( Franco O. Tzul, Daniel Vasilchuk, and George I. Makhatadze --------------------------------------------------------------- Opinion [Opinion: On being an advisor to today’s junior scientists]( [Front Matter Article] C. David Allis Leading scientists discuss current issues. --------------------------------------------------------------- Commentaries [Overexplaining or underexplaining methane’s role in climate change]( Michael J. Prather and Christopher D. Holmes [Trust and the poverty trap]( Martha J. Farah and Cayce J. Hook [Assembly and function of bHLH–PAS complexes]( Jennifer L. Fribourgh and Carrie L. Partch --------------------------------------------------------------- PNAS Plus Significance Statements [PNAS Plus Significance Statements]( Brief statements written by the authors about the significance of their papers. --------------------------------------------------------------- Physical Sciences Biophysics and Computational Biology [Fold-change detection and scale invariance of cell–cell signaling in social amoeba]( [Open Access Article] Keita Kamino, Yohei Kondo, Akihiko Nakajima, Mai Honda-Kitahara, Kunihiko Kaneko, and Satoshi Sawai [Dynamic microtubules regulate cellular contractility during T-cell activation]( King Lam Hui and Arpita Upadhyaya [Modeling the response of a tumor-suppressive network to mitogenic and oncogenic signals]( [Open Access Article] Xinyu Tian, Bo Huang, Xiao-Peng Zhang, Mingyang Lu, Feng Liu, José N. Onuchic, and Wei Wang Chemistry [Ab initio dynamics and photoionization mass spectrometry reveal ion–molecule pathways from ionized acetylene clusters to benzene cation]( Tamar Stein, Biswajit Bandyopadhyay, Tyler P. Troy, Yigang Fang, Oleg Kostko, Musahid Ahmed, and Martin Head-Gordon [H2O2-responsive liposomal nanoprobe for photoacoustic inflammation imaging and tumor theranostics via in vivo chromogenic assay]( Qian Chen, Chao Liang, Xiaoqi Sun, Jiawen Chen, Zhijuan Yang, He Zhao, Liangzhu Feng, and Zhuang Liu [Single-crystal Ih ice surfaces unveil connection between macroscopic and molecular structure]( Alexandra Brumberg, Kevin Hammonds, Ian Baker, Ellen H. G. Backus, Patrick J. Bisson, Mischa Bonn, Charles P. Daghlian, Markus D. Mezger, and Mary Jane Shultz Earth, Atmospheric, and Planetary Sciences [Enhanced CO2 uptake at a shallow Arctic Ocean seep field overwhelms the positive warming potential of emitted methane]( John W. Pohlman, Jens Greinert, Carolyn Ruppel, Anna Silyakova, Lisa Vielstädte, Michael Casso, Jürgen Mienert, and Stefan Bünz [Carbon dioxide sources from Alaska driven by increasing early winter respiration from Arctic tundra]( Róisín Commane, Jakob Lindaas, Joshua Benmergui, Kristina A. Luus, Rachel Y.-W. Chang, Bruce C. Daube, Eugénie S. Euskirchen, John M. Henderson, Anna Karion, John B. Miller, Scot M. Miller, Nicholas C. Parazoo, James T. Randerson, Colm Sweeney, Pieter Tans, Kirk Thoning, Sander Veraverbeke, Charles E. Miller, and Steven C. Wofsy Engineering [Listener evaluations of new and Old Italian violins]( Claudia Fritz, Joseph Curtin, Jacques Poitevineau, and Fan-Chia Tao Environmental Sciences [Ambiguity in the causes for decadal trends in atmospheric methane and hydroxyl]( [Open Access Article] [From the Cover] Alexander J. Turner, Christian Frankenberg, Paul O. Wennberg, and Daniel J. Jacob [Role of atmospheric oxidation in recent methane growth]( Matthew Rigby, Stephen A. Montzka, Ronald G. Prinn, James W. C. White, Dickon Young, Simon O’Doherty, Mark F. Lunt, Anita L. Ganesan, Alistair J. Manning, Peter G. Simmonds, Peter K. Salameh, Christina M. Harth, Jens Mühle, Ray F. Weiss, Paul J. Fraser, L. Paul Steele, Paul B. Krummel, Archie McCulloch, and Sunyoung Park Physics [Anomalous thermal diffusivity in underdoped YBa2Cu3O6+x]( Jiecheng Zhang, Eli M. Levenson-Falk, B. J. Ramshaw, D. A. Bonn, Ruixing Liang, W. N. Hardy, Sean A. Hartnoll, and Aharon Kapitulnik [Competing magnetic orders in the superconducting state of heavy-fermion CeRhIn5]( P. F. S. Rosa, J. Kang, Yongkang Luo, N. Wakeham, E. D. Bauer, F. Ronning, Z. Fisk, R. M. Fernandes, and J. D. Thompson [Evidence from Fermi surface analysis for the low-temperature structure of lithium]( Sabri F. Elatresh, Weizhao Cai, N. W. Ashcroft, Roald Hoffmann, Shanti Deemyad, and Stanimir A. Bonev --------------------------------------------------------------- Social Sciences Psychological and Cognitive Sciences [Body sway reflects leadership in joint music performance]( Andrew Chang, Steven R. Livingstone, Dan J. Bosnyak, and Laurel J. Trainor [The wisdom of crowds for visual search]( Mordechai Z. Juni and Miguel P. Eckstein [Listener evaluations of new and Old Italian violins]( Claudia Fritz, Joseph Curtin, Jacques Poitevineau, and Fan-Chia Tao [Community trust reduces myopic decisions of low-income individuals]( [From the Cover] Jon M. Jachimowicz, Salah Chafik, Sabeth Munrat, Jaideep C. Prabhu, and Elke U. Weber [Preferences for group dominance track and mediate the effects of macro-level social inequality and violence across societies]( [Open Access Article] Jonas R. Kunst, Ronald Fischer, Jim Sidanius, and Lotte Thomsen Sustainability Science [Identifying the landscape drivers of agricultural insecticide use leveraging evidence from 100,000 fields]( Ashley E. Larsen and Frederik Noack --------------------------------------------------------------- Biological Sciences Agricultural Sciences [Hybridizing transgenic Bt cotton with non-Bt cotton counters resistance in pink bollworm]( [Open Access Article] Peng Wan, Dong Xu, Shengbo Cong, Yuying Jiang, Yunxin Huang, Jintao Wang, Huaiheng Wu, Ling Wang, Kongming Wu, Yves Carrière, Andrea Mathias, Xianchun Li, and Bruce E. Tabashnik Applied Biological Sciences [In vivo engineering of bone tissues with hematopoietic functions and mixed chimerism]( Yu-Ru Shih, Heemin Kang, Vikram Rao, Yu-Jui Chiu, Seong Keun Kwon, and Shyni Varghese Biochemistry [Polyketide mimetics yield structural and mechanistic insights into product template domain function in nonreducing polyketide synthases]( [Open Access Article] Jesus F. Barajas, Gaurav Shakya, Gabriel Moreno, Heriberto Rivera Jr., David R. Jackson, Caitlyn L. Topper, Anna L. Vagstad, James J. La Clair, Craig A. Townsend, Michael D. Burkart, and Shiou-Chuan Tsai [H2O2-responsive liposomal nanoprobe for photoacoustic inflammation imaging and tumor theranostics via in vivo chromogenic assay]( Qian Chen, Chao Liang, Xiaoqi Sun, Jiawen Chen, Zhijuan Yang, He Zhao, Liangzhu Feng, and Zhuang Liu [Cap-binding protein 4EHP effects translation silencing by microRNAs]( Clément Chapat, Seyed Mehdi Jafarnejad, Edna Matta-Camacho, Geoffrey G. Hesketh, Idit A. Gelbart, Jan Attig, Christos G. Gkogkas, Tommy Alain, Noam Stern-Ginossar, Marc R. Fabian, Anne-Claude Gingras, Thomas F. Duchaine, and Nahum Sonenberg [Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex]( [Open Access Article] [From the Cover] Seung-Hyeon Seok, Woojong Lee, Li Jiang, Kaivalya Molugu, Aiping Zheng, Yitong Li, Sanghyun Park, Christopher A. Bradfield, and Yongna Xing [Adaptation of cone pigments found in green rods for scotopic vision through a single amino acid mutation]( Keiichi Kojima, Yuki Matsutani, Takahiro Yamashita, Masataka Yanagawa, Yasushi Imamoto, Yumiko Yamano, Akimori Wada, Osamu Hisatomi, Kanto Nishikawa, Keisuke Sakurai, and Yoshinori Shichida [Mechanism of duplex DNA destabilization by RNA-guided Cas9 nuclease during target interrogation]( [Open Access Article] Vladimir Mekler, Leonid Minakhin, and Konstantin Severinov Biophysics and Computational Biology [Fold-change detection and scale invariance of cell–cell signaling in social amoeba]( [Open Access Article] Keita Kamino, Yohei Kondo, Akihiko Nakajima, Mai Honda-Kitahara, Kunihiko Kaneko, and Satoshi Sawai [String method solution of the gating pathways for a pentameric ligand-gated ion channel]( Bogdan Lev, Samuel Murail, Frédéric Poitevin, Brett A. Cromer, Marc Baaden, Marc Delarue, and Toby W. Allen [Atypical interactions of integrin αVβ8 with pro-TGF-β1]( Jianchuan Wang, Xianchi Dong, Bo Zhao, Jing Li, Chafen Lu, and Timothy A. Springer [Dynamic remodeling of the dynamin helix during membrane constriction]( [Open Access Article] Adai Colom, Lorena Redondo-Morata, Nicolas Chiaruttini, Aurélien Roux, and Simon Scheuring [Entropic forces drive self-organization and membrane fusion by SNARE proteins]( Hakhamanesh Mostafavi, Sathish Thiyagarajan, Benjamin S. Stratton, Erdem Karatekin, Jason M. Warner, James E. Rothman, and Ben O’Shaughnessy [High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding]( Evan A. Boyle, Johan O. L. Andreasson, Lauren M. Chircus, Samuel H. Sternberg, Michelle J. Wu, Chantal K. Guegler, Jennifer A. Doudna, and William J. Greenleaf Cell Biology [Dynamic microtubules regulate cellular contractility during T-cell activation]( King Lam Hui and Arpita Upadhyaya Developmental Biology [Development of an optimized synthetic Notch receptor as an in vivo cell–cell contact sensor]( Li He, Jiuhong Huang, and Norbert Perrimon Environmental Sciences [Enhanced CO2 uptake at a shallow Arctic Ocean seep field overwhelms the positive warming potential of emitted methane]( John W. Pohlman, Jens Greinert, Carolyn Ruppel, Anna Silyakova, Lisa Vielstädte, Michael Casso, Jürgen Mienert, and Stefan Bünz [Identifying the landscape drivers of agricultural insecticide use leveraging evidence from 100,000 fields]( Ashley E. Larsen and Frederik Noack Genetics [Ectopic protein interactions within BRD4–chromatin complexes drive oncogenic megadomain formation in NUT midline carcinoma]( Artyom A. Alekseyenko, Erica M. Walsh, Barry M. Zee, Tibor Pakozdi, Peter Hsi, Madeleine E. Lemieux, Paola Dal Cin, Tan A. Ince, Peter V. Kharchenko, Mitzi I. Kuroda, and Christopher A. French [Hsp104 disaggregase at normal levels cures many [PSI+] prion variants in a process promoted by Sti1p, Hsp90, and Sis1p]( Anton Gorkovskiy, Michael Reidy, Daniel C. Masison, and Reed B. Wickner [Selective targeting of point-mutated KRAS through artificial microRNAs]( Mario Acunzo, Giulia Romano, Giovanni Nigita, Dario Veneziano, Luigi Fattore, Alessandro Laganà, Nicola Zanesi, Paolo Fadda, Matteo Fassan, Lara Rizzotto, Raleigh Kladney, Vincenzo Coppola, and Carlo M. Croce [Shelterin components mediate genome reorganization in response to replication stress]( Takeshi Mizuguchi, Nitika Taneja, Emiko Matsuda, Jon-Matthew Belton, Peter FitzGerald, Job Dekker, and Shiv I. S. Grewal Immunology and Inflammation [Aggregation of thrombin-derived C-terminal fragments as a previously undisclosed host defense mechanism]( [Open Access Article] Jitka Petrlova, Finja C. Hansen, Mariena J. A. van der Plas, Roland G. Huber, Matthias Mörgelin, Martin Malmsten, Peter J. Bond, and Artur Schmidtchen [Structural basis for cancer immunotherapy by the first-in-class checkpoint inhibitor ipilimumab]( [Open Access Article] Udupi A. Ramagopal, Weifeng Liu, Sarah C. Garrett-Thomson, Jeffrey B. Bonanno, Qingrong Yan, Mohan Srinivasan, Susan C. Wong, Alasdair Bell, Shilpa Mankikar, Vangipuram S. Rangan, Shrikant Deshpande, Alan J. Korman, and Steven C. Almo [Uric acid priming in human monocytes is driven by the AKT–PRAS40 autophagy pathway]( Tania O. Crişan, Maartje C. P. Cleophas, Boris Novakovic, Kathrin Erler, Frank L. van de Veerdonk, Hendrik G. Stunnenberg, Mihai G. Netea, Charles A. Dinarello, and Leo A. B. Joosten [Autoantibody-induced internalization of CNS AQP4 water channel and EAAT2 glutamate transporter requires astrocytic Fc receptor]( [Open Access Article] Shannon R. Hinson, Ian C. Clift, Ningling Luo, Thomas J. Kryzer, and Vanda A. Lennon [Microbiota promotes systemic T-cell survival through suppression of an apoptotic factor]( Raymond Soto, Charisse Petersen, Camille L. Novis, Jason L. Kubinak, Rickesha Bell, W. Zac Stephens, Thomas E. Lane, Robert S. Fujinami, Alberto Bosque, Ryan M. O’Connell, and June L. Round Medical Sciences [Erythritol is a pentose-phosphate pathway metabolite and associated with adiposity gain in young adults]( Katie C. Hootman, Jean-Pierre Trezzi, Lisa Kraemer, Lindsay S. Burwell, Xiangyi Dong, Kristin A. Guertin, Christian Jaeger, Patrick J. Stover, Karsten Hiller, and Patricia A. Cassano [Hypoxia treatment reverses neurodegenerative disease in a mouse model of Leigh syndrome]( [Open Access Article] Michele Ferrari, Isha H. Jain, Olga Goldberger, Emanuele Rezoagli, Robrecht Thoonen, Kai-Hung Chen, David E. Sosnovik, Marielle Scherrer-Crosbie, Vamsi K. Mootha, and Warren M. Zapol [Combined HMG-COA reductase and prenylation inhibition in treatment of CCM]( [Open Access Article] Sayoko Nishimura, Ketu Mishra-Gorur, JinSeok Park, Yulia V. Surovtseva, Said M. Sebti, Andre Levchenko, Angeliki Louvi, and Murat Gunel Microbiology [Coronavirus nonstructural protein 15 mediates evasion of dsRNA sensors and limits apoptosis in macrophages]( Xufang Deng, Matthew Hackbart, Robert C. Mettelman, Amornrat O’Brien, Anna M. Mielech, Guanghui Yi, C. Cheng Kao, and Susan C. Baker [Structural basis for spumavirus GAG tethering to chromatin]( [Open Access Article] Paul Lesbats, Erik Serrao, Daniel P. Maskell, Valerie E. Pye, Nicola O’Reilly, Dirk Lindemann, Alan N. Engelman, and Peter Cherepanov Neuroscience [mTORC1 promotes proliferation of immature Schwann cells and myelin growth of differentiated Schwann cells]( Bogdan Beirowski, Keit Men Wong, Elisabetta Babetto, and Jeffrey Milbrandt [Maturation arrest in early postnatal sensory receptors by deletion of the miR-183/96/182 cluster in mouse]( [Open Access Article] Jianguo Fan, Li Jia, Yan Li, Seham Ebrahim, Helen May-Simera, Alynda Wood, Robert J. Morell, Pinghu Liu, Jingqi Lei, Bechara Kachar, Leonardo Belluscio, Haohua Qian, Tiansen Li, Wei Li, Graeme Wistow, and Lijin Dong [Social propinquity in rodents as measured by tube cooccupancy differs between inbred and outbred genotypes]( Alexander H. Tuttle, Shannon Tansley, Kimberly Dossett, Sarasa Tohyama, Arkady Khoutorsky, Sioui Maldonado-Bouchard, Liane Stein, Lindsey Gerstein, Hayley Crawhall-Duk, Rebecca Pearl, Melissa Sukosd, Philip Leger, Oliver M. Hardt, David Yachnin, Jean-Sebastien Austin, Claire M. Chan, Tine Pooters, Isabelle Groves, Loren J. Martin, Nahum Sonenberg, Christos G. Gkogkas, and Jeffrey S. Mogil [Heritability analysis with repeat measurements and its application to resting-state functional connectivity]( Tian Ge, Avram J. Holmes, Randy L. Buckner, Jordan W. Smoller, and Mert R. Sabuncu [Metaplasticity mechanisms restore plasticity and associativity in an animal model of Alzheimer’s disease]( Qin Li, Sheeja Navakkode, Martin Rothkegel, Tuck Wah Soong, Sreedharan Sajikumar, and Martin Korte [Intersectin 1 is a component of the Reelin pathway to regulate neuronal migration and synaptic plasticity in the hippocampus]( [Open Access Article] Burkhard Jakob, Gaga Kochlamazashvili, Maria Jäpel, Aziz Gauhar, Hans H. Bock, Tanja Maritzen, and Volker Haucke Pharmacology [Common general anesthetic propofol impairs kinesin processivity]( Brandon M. Bensel, Stephanie Guzik-Lendrum, Erin M. Masucci, Kellie A. Woll, Roderic G. Eckenhoff, and Susan P. Gilbert [Functional genomics in Brugia malayi reveal diverse muscle nAChRs and differences between cholinergic anthelmintics]( [Open Access Article] Saurabh Verma, Sudhanva Srinivas Kashyap, Alan Patrick Robertson, and Richard John Martin Physiology [Exclusion of alternative exon 33 of CaV1.2 calcium channels in heart is proarrhythmogenic]( Guang Li, Juejin Wang, Ping Liao, Peter Bartels, Hengyu Zhang, Dejie Yu, Mui Cheng Liang, Kian Keong Poh, Chye Yun Yu, Fengli Jiang, Tan Fong Yong, Yuk Peng Wong, Zhenyu Hu, Hua Huang, Guangqin Zhang, Mary Joyce Galupo, Jin-Song Bian, Sathivel Ponniah, Scott Lee Trasti, Kelvin See, Roger Foo, Uta C. Hoppe, Stefan Herzig, and Tuck Wah Soong Plant Biology [Chromosome-level genome assembly and transcriptome of the green alga Chromochloris zofingiensis illuminates astaxanthin production]( [Open Access Article] Melissa S. Roth, Shawn J. Cokus, Sean D. Gallaher, Andreas Walter, David Lopez, Erika Erickson, Benjamin Endelman, Daniel Westcott, Carolyn A. Larabell, Sabeeha S. Merchant, Matteo Pellegrini, and Krishna K. Niyogi Psychological and Cognitive Sciences [The wisdom of crowds for visual search]( Mordechai Z. Juni and Miguel P. Eckstein [Biological origins of color categorization]( [From the Cover] Alice E. Skelton, Gemma Catchpole, Joshua T. Abbott, Jenny M. Bosten, and Anna Franklin Systems Biology [Modeling the response of a tumor-suppressive network to mitogenic and oncogenic signals]( [Open Access Article] Xinyu Tian, Bo Huang, Xiao-Peng Zhang, Mingyang Lu, Feng Liu, José N. Onuchic, and Wei Wang --------------------------------------------------------------- Corrections (Online Only) [Correction for Zastrow, News Feature: Is video game addiction really an addiction?]( [Correction for Xu et al., BCL6 promotes glioma and serves as a therapeutic target]( [Cover] Open Access From the Cover Inaugural Article Classic Cozzarelli Prize Winner Front Matter --------------------------------------------------------------- This message was sent to {EMAIL}. [Unsubscribe]( from or [edit]( your subscription for this service. Or by mail: Customer Service * 973 University Avenue * Los Gatos, CA 95032 * U.S.A. Copyright © 2017 by the National Academy of Sciences