[PNAS] [PNAS Nexus: A new open access journal. Find out more.](/cgi/adclick/?ad=56236&adclick=true&url=https%3A%2F%2Fwww.pnas.org%2Fpage%2Fupdates%23nexus-launch) Â [November 30, 2021; Vol. 118, No. 48](
) This Week in PNAS
[In This Issue]( This week's research highlights
--------------------------------------------------------------- Inner Workings
[Inner Working: The hidden lives of volcanic plumes provide clues about eruption activity](
Sid Perkins
An over-the-shoulder look at scientists at work
--------------------------------------------------------------- Profile
[Profile of Ginés Morata](
Beth Azar
The life and work of NAS members
--------------------------------------------------------------- Commentaries
[George Floyd’s death affected Black and White families differently](
Stacey Sinclair and Jordan G. Starck
[Mitochondria–cytoskeleton interactions in mammalian sperm revealed by cryoelectron tomography](
Huafeng Wang and Jean-Ju Chung
[Integrated pest management can still deliver on its promise, with help from the bees](
Rufus Isaacs --------------------------------------------------------------- Perspective
[The crucial role of genome-wide genetic variation in conservation](
Marty Kardos, Ellie E. Armstrong, Sarah W. Fitzpatrick, Samantha Hauser, Philip W. Hedrick, Joshua M. Miller, David A. Tallmon, and W. Chris Funk --------------------------------------------------------------- Physical Sciences
Applied Mathematics
[The physical basis of mollusk shell chiral coiling](
Régis Chirat, Alain Goriely, and Derek E. Moulton Applied Physical Sciences
[Scaling concepts in ‘omics: Nuclear lamin-B scales with tumor growth and often predicts poor prognosis, unlike fibrosis](
Manasvita Vashisth, Sangkyun Cho, Jerome Irianto, Yuntao Xia, Mai Wang, Brandon Hayes, Daniel Wieland, Rebecca Wells, Farshid Jafarpour, Andrea Liu, and Dennis E. Discher Biophysics and Computational Biology
[Amyloid β 42 fibril structure based on small-angle scattering](
Veronica Lattanzi, Ingemar André, Urs Gasser, Marija Dubackic, Ulf Olsson, and Sara Linse
[Correlated diffusion in lipid bilayers](
Rafael L. Schoch, Frank L. H. Brown, and Gilad Haran
[Plant–environment microscopy tracks interactions of Bacillus subtilis with plant roots across the entire rhizosphere](
Yangminghao Liu, Daniel Patko, Ilonka Engelhardt, Timothy S. George, Nicola R. Stanley-Wall, Vincent Ladmiral, Bruno Ameduri, Tim J. Daniell, Nicola Holden, Michael P. MacDonald, and Lionel X. Dupuy
[A traveling-wave solution for bacterial chemotaxis with growth](
Avaneesh V. Narla, Jonas Cremer, and Terence Hwa
[Three-dimensional virtual histology of the human hippocampus based on phase-contrast computed tomography](
Marina Eckermann, Bernhard Schmitzer, Franziska van der Meer, Jonas Franz, Ove Hansen, Christine Stadelmann, and Tim Salditt Chemistry
[Seeds of imperfection rule the mesocrystalline disorder in natural anhydrite single crystals](
Tomasz M. Stawski, Glen J. Smales, Ernesto Scoppola, Diwaker Jha, Luiz F. G. Morales, Alicia Moya, Richard Wirth, Brian R. Pauw, Franziska Emmerling, and Alexander E. S. Van Driessche
[Click chemistry–enabled CRISPR screening reveals GSK3 as a regulator of PLD signaling](
Timothy W. Bumpus, Shiying Huang, Reika Tei, and Jeremy M. Baskin
[Nanosized and metastable molybdenum oxides as negative electrode materials for durable high-energy aqueous Li-ion batteries](
Jeongsik Yun, Ryota Sagehashi, Yoshihiko Sato, Takuya Masuda, Satoshi Hoshino, Hongahally Basappa Rajendra, Kazuki Okuno, Akihisa Hosoe, Aliaksandr S. Bandarenka, and Naoaki Yabuuchi Computer Sciences
[Neural networks to learn protein sequence–function relationships from deep mutational scanning data](
Sam Gelman, Sarah A. Fahlberg, Pete Heinzelman, Philip A. Romero, and Anthony Gitter Earth, Atmospheric, and Planetary Sciences
[Stochastic rectification of fast oscillations on slow manifold closures](
Mickaël D. Chekroun, Honghu Liu, and James C. McWilliams Environmental Sciences
[Harmful algal blooms and cyanotoxins in Lake Amatitlán, Guatemala, coincided with ancient Maya occupation in the watershed](
Matthew Neal Waters, Mark Brenner, Jason Hilleary Curtis, Claudia Suseth Romero-Oliva, Margaret Dix, and Manuel Cano
[Tailoring of electronic and surface structures boosts exciton-triggering photocatalysis for singlet oxygen generation](
Dongpeng Zhang, Pengfei Wang, Junhui Wang, Yanxiao Li, Yuguo Xia, and Sihui Zhan Engineering
[Light-driven dynamic surface wrinkles for adaptive visible camouflage](
Tianjiao Ma, Jing Bai, Tiantian Li, Shuai Chen, Xiaodong Ma, Jie Yin, and Xuesong Jiang Physics
[Liquid walls and interfaces in arbitrary directions stabilized by vibrations](
Benjamin Apffel, Samuel Hidalgo-Caballero, Antonin Eddi, and Emmanuel Fort
[Facile self-assembly of colloidal diamond from tetrahedral patchy particles via ring selection](
Andreas Neophytou, Dwaipayan Chakrabarti, and Francesco Sciortino
[Nonlinear nanoelectrodynamics of a Weyl metal](
Yinming Shao, Ran Jing, Sang Hoon Chae, Chong Wang, Zhiyuan Sun, Eve Emmanouilidou, Suheng Xu, Dorri Halbertal, Baichang Li, Anjaly Rajendran, Francesco L. Ruta, Lin Xiong, Yinan Dong, Alexander S. McLeod, Sai S. Sunku, James C. Hone, Joel Moore, Joe Orenstein, James G. Analytis, Andrew J. Millis, Ni Ni, Di Xiao, and D. N. Basov Statistics
[Distributional conformal prediction](
Victor Chernozhukov, Kaspar Wüthrich, and Yinchu Zhu --------------------------------------------------------------- Social Sciences
Anthropology
[The earliest adobe monumental architecture in the Americas](
Ana Cecilia Mauricio, Rolf Grieseler, Andrew R. Heller, Alice R. Kelley, Francisco Rumiche, Daniel H. Sandweiss, and Willem Viveen Economic Sciences
[Rational regulation of water-seeking effort in rodents](
Pamela Reinagel Psychological and Cognitive Sciences
[Gender stereotypes about interests start early and cause gender disparities in computer science and engineering](
Allison Master, Andrew N. Meltzoff, and Sapna Cheryan
[An implicit representation of stimulus ambiguity in pupil size](
Jackson E. Graves, Paul Egré, Daniel Pressnitzer, and Vincent de Gardelle
[Episodic memory enhancement versus impairment is determined by contextual similarity across events](
Wouter R. Cox, Simone Dobbelaar, Martijn Meeter, Merel Kindt, and Vanessa A. van Ast --------------------------------------------------------------- Biological Sciences
Agricultural Sciences
[Defective cytokinin signaling reprograms lipid and flavonoid gene-to-metabolite networks to mitigate high salinity in Arabidopsis](
Mostafa Abdelrahman, Rie Nishiyama, Cuong Duy Tran, Miyako Kusano, Ryo Nakabayashi, Yozo Okazaki, Fumio Matsuda, Ricardo A. Chávez Montes, Mohammad Golam Mostofa, Weiqiang Li, Yasuko Watanabe, Atsushi Fukushima, Maho Tanaka, Motoaki Seki, Kazuki Saito, Luis Herrera-Estrella, and Lam-Son Phan Tran Applied Biological Sciences
[Hexavalent sperm-binding IgG antibody released from vaginal film for development of potent on-demand nonhormonal female contraception](
Bhawana Shrestha, Kathleen Vincent, Alison Schaefer, Yong Zhu, Gracie Vargas, Massoud Motamedi, Kelsi Swope, Josh Morton, Carrie Simpson, Henry Pham, Miles B. Brennan, Michael H. Pauly, Larry Zeitlin, Barry Bratcher, Kevin J. Whaley, Thomas R. Moench, and Samuel K. Lai Biochemistry
[Structure of the translating Neurospora ribosome arrested by cycloheximide](
Lunda Shen, Zhaoming Su, Kailu Yang, Cheng Wu, Thomas Becker, Deborah Bell-Pedersen, Junjie Zhang, and Matthew S. Sachs
[Molecular structure of an open human KATP channel](
Chen Zhao and Roderick MacKinnon Biophysics and Computational Biology
[Scaling concepts in ‘omics: Nuclear lamin-B scales with tumor growth and often predicts poor prognosis, unlike fibrosis](
Manasvita Vashisth, Sangkyun Cho, Jerome Irianto, Yuntao Xia, Mai Wang, Brandon Hayes, Daniel Wieland, Rebecca Wells, Farshid Jafarpour, Andrea Liu, and Dennis E. Discher
[Amyloid β 42 fibril structure based on small-angle scattering](
Veronica Lattanzi, Ingemar André, Urs Gasser, Marija Dubackic, Ulf Olsson, and Sara Linse
[Correlated diffusion in lipid bilayers](
Rafael L. Schoch, Frank L. H. Brown, and Gilad Haran
[Neural networks to learn protein sequence–function relationships from deep mutational scanning data](
Sam Gelman, Sarah A. Fahlberg, Pete Heinzelman, Philip A. Romero, and Anthony Gitter Cell Biology
[Click chemistry–enabled CRISPR screening reveals GSK3 as a regulator of PLD signaling](
Timothy W. Bumpus, Shiying Huang, Reika Tei, and Jeremy M. Baskin
[Translesion polymerase eta both facilitates DNA replication and promotes increased human genetic variation at common fragile sites](
Shyam Twayana, Albino Bacolla, Angelica Barreto-Galvez, Ruth B. De-Paula, William C. Drosopoulos, Settapong T. Kosiyatrakul, Eric E. Bouhassira, John A. Tainer, Advaitha Madireddy, and Carl L. Schildkraut
[Chromatin bridges, not micronuclei, activate cGAS after drug-induced mitotic errors in human cells](
Patrick J. Flynn, Peter D. Koch, and Timothy J. Mitchison Developmental Biology
[The physical basis of mollusk shell chiral coiling](
Régis Chirat, Alain Goriely, and Derek E. Moulton Ecology
[Past insecticide exposure reduces bee reproduction and population growth rate](
Clara Stuligross and Neal M. Williams
[Warming winters in lakes: Later ice onset promotes consumer overwintering and shapes springtime planktonic food webs](
Marie-Pier Hébert, Beatrix E. Beisner, Milla Rautio, and Gregor F. Fussmann
[Host genotype structures the microbiome of a globally dispersed marine phytoplankton](
Olivia M. Ahern, Kerry A. Whittaker, Tiffany C. Williams, Dana E. Hunt, and Tatiana A. Rynearson Environmental Sciences
[Harmful algal blooms and cyanotoxins in Lake Amatitlán, Guatemala, coincided with ancient Maya occupation in the watershed](
Matthew Neal Waters, Mark Brenner, Jason Hilleary Curtis, Claudia Suseth Romero-Oliva, Margaret Dix, and Manuel Cano
[Molecular mechanisms of sperm motility are conserved in an early-branching metazoan](
Kelsey F. Speer, Luella Allen-Waller, Dana R. Novikov, and Katie L. Barott Evolution
[Evolutionary change in the construction of the nursery environment when parents are prevented from caring for their young directly](
Ana Duarte, Darren Rebar, Allysa C. Hallett, Benjamin J. M. Jarrett, and Rebecca M. Kilner Genetics
[Ccp1-Ndc80 switch at the N terminus of CENP-T regulates kinetochore assembly](
Qianhua Dong, Xue-lei Liu, Xiao-hui Wang, Yu Zhao, Yu-hang Chen, and Fei Li
[BAP1 forms a trimer with HMGB1 and HDAC1 that modulates gene × environment interaction with asbestos](
Flavia Novelli, Angela Bononi, Qian Wang, Fang Bai, Simone Patergnani, Franz Kricek, Ellinor Haglund, Joelle S. Suarez, Mika Tanji, Ronghui Xu, Yasutaka Takanishi, Michael Minaai, Sandra Pastorino, Paul Morris, Greg Sakamoto, Harvey I. Pass, Haithem Barbour, Giovanni Gaudino, Carlotta Giorgi, Paolo Pinton, Jose N. Onuchic, Haining Yang, and Michele Carbone Immunology and Inflammation
[Lymph node formation and B cell homeostasis require IKK-α in distinct endothelial cell–derived compartments](
Kelly A. McCorkell, Nipun Jayachandran, Michelle D. Cully, Jacquelyn Freund-Brown, Tiffany Weinkopff, James Monslow, Yinling Hu, Ellen Puré, Bruce D. Freedman, Jorge I. Alvarez, Michael P. Cancro, and Michael J. May
[Colon cancer cells acquire immune regulatory molecules from tumor-infiltrating lymphocytes by trogocytosis](
Jae Hun Shin, Jaekwang Jeong, Stephen E. Maher, Heon-Woo Lee, Jaechul Lim, and Alfred L. M. Bothwell Medical Sciences
[Exploring the signaling space of a GPCR using bivalent ligands with a rigid oligoproline backbone](
Nina Romantini, Shahidul Alam, Stefanie Dobitz, Martin Spillmann, Martina De Foresta, Roger Schibli, Gebhard F. X. Schertler, Helma Wennemers, Xavier Deupi, Martin Behe, and Philipp Berger
[Three-dimensional virtual histology of the human hippocampus based on phase-contrast computed tomography](
Marina Eckermann, Bernhard Schmitzer, Franziska van der Meer, Jonas Franz, Ove Hansen, Christine Stadelmann, and Tim Salditt Microbiology
[Nanometer-resolution in situ structure of the SARS-CoV-2 postfusion spike protein](
Linhua Tai, Guoliang Zhu, Minnan Yang, Lei Cao, Xiaorui Xing, Guoliang Yin, Chun Chan, Chengfeng Qin, Zihe Rao, Xiangxi Wang, Fei Sun, and Yun Zhu
[Actinobacteria challenge the paradigm: A unique protein architecture for a well-known, central metabolic complex](
Eduardo M. Bruch, Pierre Vilela, Lu Yang, Alexandra Boyko, Norik Lexa-Sapart, Bertrand Raynal, Pedro M. Alzari, and Marco Bellinzoni
[Th17 cell master transcription factor RORC2 regulates HIV-1 gene expression and viral outgrowth](
Tomas Raul Wiche Salinas, Yuwei Zhang, Daniele Sarnello, Alexander Zhyvoloup, Laurence Raymond Marchand, Augustine Fert, Delphine Planas, Manivel Lodha, Debashree Chatterjee, Katarzyna Karwacz, Sally Oxenford, Jean-Pierre Routy, David Irlbeck, Heather Amrine-Madsen, Petronela Ancuta, and Ariberto Fassati
[Anatomy of an extensively drug-resistant Klebsiella pneumoniae outbreak in Tuscany, Italy](
Melissa J. Martin, Brendan W. Corey, Filomena Sannio, Lindsey R. Hall, Ulrike MacDonald, Brendan T. Jones, Emma G. Mills, Casey Harless, Jason Stam, Rosslyn Maybank, Yoon Kwak, Katharina Schaufler, Karsten Becker, Nils-Olaf Hübner, Stefania Cresti, Giacinta Tordini, Marcello Valassina, Maria Grazia Cusi, Jason W. Bennett, Thomas A. Russo, Patrick T. McGann, Francois Lebreton, and Jean-Denis Docquier
[Gliding motility of Plasmodium merozoites](
Kazuhide Yahata, Melissa N. Hart, Heledd Davies, Masahito Asada, Samuel C. Wassmer, Thomas J. Templeton, Moritz Treeck, Robert W. Moon, and Osamu Kaneko Neuroscience
[Rational regulation of water-seeking effort in rodents](
Pamela Reinagel
[Synaptotagmin 1 oligomerization via the juxtamembrane linker regulates spontaneous and evoked neurotransmitter release](
Kevin C. Courtney, Jason D. Vevea, Yueqi Li, Zhenyong Wu, Zhao Zhang, and Edwin R. Chapman
[A role of anterior cingulate cortex in the emergence of worker–parasite relationship](
Soyoun Ahn, Yujeong Kang, Jong Won Lee, Se Jin Jeong, Yoo Jin Lee, Soomin Lee, Jeongyeon Kim, Ja Wook Koo, Jeansok J. Kim, and Min Whan Jung
[Temporal order of signal propagation within and across intrinsic brain networks](
Mike J. Veit, Aaron Kucyi, Wenhan Hu, Chao Zhang, Baotian Zhao, Zhihao Guo, Bowen Yang, Clara Sava-Segal, Claire Perry, Jianguo Zhang, Kai Zhang, and Josef Parvizi
[An implicit representation of stimulus ambiguity in pupil size](
Jackson E. Graves, Paul Egré, Daniel Pressnitzer, and Vincent de Gardelle
[Hippocampal neurons’ cytosolic and membrane-bound ribosomal transcript profiles are differentially regulated by learning and subsequent sleep](
James Delorme, Lijing Wang, Varna Kodoth, Yifan Wang, Jingqun Ma, Sha Jiang, and Sara J. Aton Pharmacology
[G protein signaling–biased mu opioid receptor agonists that produce sustained G protein activation are noncompetitive agonists](
Edward L. Stahl, Cullen L. Schmid, Agnes Acevedo-Canabal, Cai Read, Travis W. Grim, Nicole M. Kennedy, Thomas D. Bannister, and Laura M. Bohn Physiology
[Claudin-2 and claudin-12 form independent, complementary pores required to maintain calcium homeostasis](
Megan R. Beggs, Kennedi Young, Wanling Pan, Debbie D. O’Neill, Matthew Saurette, Allein Plain, Juraj Rievaj, Michael R. Doschak, Emmanuelle Cordat, Henrik Dimke, and R. Todd Alexander
[Pregnancy and weaning regulate human maternal liver size and function](
Alexandra Q. Bartlett, Kimberly K. Vesco, Jonathan Q. Purnell, Melanie Francisco, Erica Goddard, Xiangnan Guan, Andrea DeBarber, Michael C. Leo, Eric Baetscher, William Rooney, Willscott Naugler, Alexander R. Guimaraes, Patrick Catalano, Zheng Xia, and Pepper Schedin
[Vitexin inhibits APEX1 to counteract the flow-induced endothelial inflammation](
Chuan-Rong Zhao, Fang-Fang Yang, Qinghua Cui, Dong Wang, Yiran Zhou, Yi-Shuan Li, Yun-Peng Zhang, Run-Ze Tang, Wei-Juan Yao, Xiaohong Wang, Wei Pang, Jia-Nan Zhao, Zhi-Tong Jiang, Juan-Juan Zhu, Shu Chien, and Jing Zhou Plant Biology
[Plant–environment microscopy tracks interactions of Bacillus subtilis with plant roots across the entire rhizosphere](
Yangminghao Liu, Daniel Patko, Ilonka Engelhardt, Timothy S. George, Nicola R. Stanley-Wall, Vincent Ladmiral, Bruno Ameduri, Tim J. Daniell, Nicola Holden, Michael P. MacDonald, and Lionel X. Dupuy Population Biology
[A traveling-wave solution for bacterial chemotaxis with growth](
Avaneesh V. Narla, Jonas Cremer, and Terence Hwa --------------------------------------------------------------- Corrections
[Correction for Lau et al., Rapid responses of soil microorganisms improve plant fitness in novel environments]( [Correction for Kraus et al., Americans misperceive racial economic equality]( [Correction for Wainright et al., Species invasion progressively disrupts the trophic structure of native food webs]( --------------------------------------------------------------- SI Correction
[Correction to Supporting Information for Volkov et al., Thyroid hormone receptors mediate two distinct mechanisms of long-wavelength vision]( [Cover] --------------------------------------------------------------- This message was sent to {EMAIL}. [Unsubscribe]( from or [edit]( your subscription for this service.
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