PNAS Table of Contents for September 21, 2021; Vol. 118, No. 38 is now complete

[PNAS] [PNAS Classic Portal. Access now.](/cgi/adclick/?ad=56098&adclick=true&url=https%3A%2F%2Fwww.pnas.org%2Fpage%2Fabout%2Fclassics)   [September 21, 2021; Vol. 118, No. 38]( ) This Week in PNAS [In This Issue]( This week's research highlights --------------------------------------------------------------- Opinion [Opinion: We need biosphere stewardship that protects carbon sinks and builds resilience]( Johan Rockström, Tim Beringer, David Hole, Bronson Griscom, Michael B. Mascia, Carl Folke, and Felix Creutzig Leading scientists discuss current issues --------------------------------------------------------------- Profile [Profile of Ruth Lehmann]( Jennifer Viegas The life and work of NAS members --------------------------------------------------------------- Commentaries [Mayfly metamorphosis: Adult winged insects that molt]( Stuart E. Reynolds [Asymptomatic infection is the pandemic’s dark matter]( David N. Fisman and Ashleigh R. Tuite [Using PET imaging to track STING-induced interferon signaling]( Enitome E. Bafor and Howard A. Young [Looks can be deceiving: Bacterial enzymes work through unanticipated mechanism]( Joshua D. Shirley and Erin E. Carlson --------------------------------------------------------------- Letters [Differential involvement of CA2 in internally vs. externally driven hippocampal sequences]( Andrew B. Lehr and Tristan M. Stöber [Reply to Lehr and Stöber: What’s in a name? On the distinction between temporal coding and internally driven activity]( Christopher J. MacDonald and Susumu Tonegawa --------------------------------------------------------------- Physical Sciences Applied Mathematics [Geometry of gene regulatory dynamics]( David A. Rand, Archishman Raju, Meritxell Sáez, Francis Corson, and Eric D. Siggia Applied Physical Sciences [An expression for the angle of repose of dry cohesive granular materials on Earth and in planetary environments]( Filip Elekes and Eric J. R. Parteli [Dynamics of thin precursor film in wetting of nanopatterned surfaces]( Utkarsh Anand, Tanmay Ghosh, Zainul Aabdin, Siddardha Koneti, XiuMei Xu, Frank Holsteyns, and Utkur Mirsaidov [A strong nonequilibrium bound for sorting of cross-linkers on growing biopolymers]( Yuqing Qiu, Michael Nguyen, Glen M. Hocky, Aaron R. Dinner, and Suriyanarayanan Vaikuntanathan Biophysics and Computational Biology [Critical role of minor eggcase silk component in promoting spidroin chain alignment and strong fiber formation]( Tiantian Fan, Ruiqi Qin, Yan Zhang, Jingxia Wang, Jing-Song Fan, Xiangli Bai, Wensu Yuan, Weidong Huang, Shuo Shi, Xun-Cheng Su, Daiwen Yang, and Zhi Lin Chemistry [Frustrated peptide chains at the fibril tip control the kinetics of growth of amyloid-β fibrils]( Yuechuan Xu, Kaitlin Knapp, Kyle N. Le, Nicholas P. Schafer, Mohammad S. Safari, Aram Davtyan, Peter G. Wolynes, and Peter G. Vekilov [Genuine divalent magnesium-ion storage and fast diffusion kinetics in metal oxides at room temperature]( Jinlin Yang, Jibiao Li, Wenbin Gong, and Fengxia Geng [Machine learning potentials for complex aqueous systems made simple]( Christoph Schran, Fabian L. Thiemann, Patrick Rowe, Erich A. Müller, Ondrej Marsalek, and Angelos Michaelides Computer Sciences [Postmortem memory of public figures in news and social media]( Robert West, Jure Leskovec, and Christopher Potts Earth, Atmospheric, and Planetary Sciences [North Atlantic jet stream projections in the context of the past 1,250 years]( Matthew B. Osman, Sloan Coats, Sarah B. Das, Joseph R. McConnell, and Nathan Chellman Engineering [Identifying extracellular vesicle populations from single cells]( Jonas M. Nikoloff, Mario A. Saucedo-Espinosa, André Kling, and Petra S. Dittrich [Stagnation points control chaotic fluctuations in viscoelastic porous media flow]( Simon J. Haward, Cameron C. Hopkins, and Amy Q. Shen [Robust, self-adhesive, reinforced polymeric nanofilms enabling gas-permeable dry electrodes for long-term application]( Yan Wang, Sunghoon Lee, Haoyang Wang, Zhi Jiang, Yasutoshi Jimbo, Chunya Wang, Binghao Wang, Jae Joon Kim, Mari Koizumi, Tomoyuki Yokota, and Takao Someya [Micromotor-based localized electroporation and gene transfection of mammalian cells]( Yue Wu, Afu Fu, and Gilad Yossifon [Engineered SARS-CoV-2 receptor binding domain improves manufacturability in yeast and immunogenicity in mice]( Neil C. Dalvie, Sergio A. Rodriguez-Aponte, Brittany L. Hartwell, Lisa H. Tostanoski, Andrew M. Biedermann, Laura E. Crowell, Kawaljit Kaur, Ozan S. Kumru, Lauren Carter, Jingyou Yu, Aiquan Chang, Katherine McMahan, Thomas Courant, Celia Lebas, Ashley A. Lemnios, Kristen A. Rodrigues, Murillo Silva, Ryan S. Johnston, Christopher A. Naranjo, Mary Kate Tracey, Joseph R. Brady, Charles A. Whittaker, Dongsoo Yun, Natalie Brunette, Jing Yang Wang, Carl Walkey, Brooke Fiala, Swagata Kar, Maciel Porto, Megan Lok, Hanne Andersen, Mark G. Lewis, Kerry R. Love, Danielle L. Camp, Judith Maxwell Silverman, Harry Kleanthous, Sangeeta B. Joshi, David B. Volkin, Patrice M. Dubois, Nicolas Collin, Neil P. King, Dan H. Barouch, Darrell J. Irvine, and J. Christopher Love Environmental Sciences [Emerging forest–peatland bistability and resilience of European peatland carbon stores]( Ype van der Velde, Arnaud J. A. M. Temme, Jelmer J. Nijp, Maarten C. Braakhekke, George A. K. van Voorn, Stefan C. Dekker, A. Johannes Dolman, Jakob Wallinga, Kevin J. Devito, Nicholas Kettridge, Carl A. Mendoza, Lammert Kooistra, Merel B. Soons, and Adriaan J. Teuling [Bluefin tuna reveal global patterns of mercury pollution and bioavailability in the world's oceans]( Chun-Mao Tseng, Shin-Jing Ang, Yi-Sheng Chen, Jen-Chieh Shiao, Carl H. Lamborg, Xiaoshuai He, and John R. Reinfelder [Evidence for biosurfactant-induced flow in corners and bacterial spreading in unsaturated porous media]( Judy Q. Yang, Joseph E. Sanfilippo, Niki Abbasi, Zemer Gitai, Bonnie L. Bassler, and Howard A. Stone Physics [Submersed micropatterned structures control active nematic flow, topology, and concentration]( Kristian Thijssen, Dimitrius A. Khaladj, S. Ali Aghvami, Mohamed Amine Gharbi, Seth Fraden, Julia M. Yeomans, Linda S. Hirst, and Tyler N. Shendruk --------------------------------------------------------------- Social Sciences Psychological and Cognitive Sciences [Conversations about race in Black and White US families: Before and after George Floyd’s death]( J. Nicky Sullivan, Jennifer L. Eberhardt, and Steven O. Roberts [Testing the efficacy of three informational interventions for reducing misperceptions of the Black–White wealth gap]( Bennett Callaghan, Leilah Harouni, Cydney H. Dupree, Michael W. Kraus, and Jennifer A. Richeson Social Sciences [Postmortem memory of public figures in news and social media]( Robert West, Jure Leskovec, and Christopher Potts [Citizens from 13 countries share similar preferences for COVID-19 vaccine allocation priorities]( Raymond Duch, Laurence S. J. Roope, Mara Violato, Matias Fuentes Becerra, Thomas S. Robinson, Jean-Francois Bonnefon, Jorge Friedman, Peter John Loewen, Pavan Mamidi, Alessia Melegaro, Mariana Blanco, Juan Vargas, Julia Seither, Paolo Candio, Ana Gibertoni Cruz, Xinyang Hua, Adrian Barnett, and Philip M. Clarke --------------------------------------------------------------- Biological Sciences Agricultural Sciences [Integrated farming with intercropping increases food production while reducing environmental footprint]( Qiang Chai, Thomas Nemecek, Chang Liang, Cai Zhao, Aizhong Yu, Jeffrey A. Coulter, Yifan Wang, Falong Hu, Li Wang, Kadambot H. M. Siddique, and Yantai Gan [Legacy genetics of Arachis cardenasii in the peanut crop shows the profound benefits of international seed exchange]( David J. Bertioli, Josh Clevenger, Ignacio J. Godoy, H. T. Stalker, Shona Wood, Joáo F. Santos, Carolina Ballén-Taborda, Brian Abernathy, Vania Azevedo, Jacqueline Campbell, Carolina Chavarro, Ye Chu, Andrew D. Farmer, Daniel Fonceka, Dongying Gao, Jane Grimwood, Neil Halpin, Walid Korani, Marcos D. Michelotto, Peggy Ozias-Akins, Justin Vaughn, Ramey Youngblood, Marcio C. Moretzsohn, Graeme C. Wright, Scott A. Jackson, Steven B. Cannon, Brian E. Scheffler, and Soraya C. M. Leal-Bertioli Applied Biological Sciences [Engineered SARS-CoV-2 receptor binding domain improves manufacturability in yeast and immunogenicity in mice]( Neil C. Dalvie, Sergio A. Rodriguez-Aponte, Brittany L. Hartwell, Lisa H. Tostanoski, Andrew M. Biedermann, Laura E. Crowell, Kawaljit Kaur, Ozan S. Kumru, Lauren Carter, Jingyou Yu, Aiquan Chang, Katherine McMahan, Thomas Courant, Celia Lebas, Ashley A. Lemnios, Kristen A. Rodrigues, Murillo Silva, Ryan S. Johnston, Christopher A. Naranjo, Mary Kate Tracey, Joseph R. Brady, Charles A. Whittaker, Dongsoo Yun, Natalie Brunette, Jing Yang Wang, Carl Walkey, Brooke Fiala, Swagata Kar, Maciel Porto, Megan Lok, Hanne Andersen, Mark G. Lewis, Kerry R. Love, Danielle L. Camp, Judith Maxwell Silverman, Harry Kleanthous, Sangeeta B. Joshi, David B. Volkin, Patrice M. Dubois, Nicolas Collin, Neil P. King, Dan H. Barouch, Darrell J. Irvine, and J. Christopher Love [Assisted gene flow using cryopreserved sperm in critically endangered coral]( Mary Hagedorn, Christopher A. Page, Keri L. O’Neil, Daisy M. Flores, Lucas Tichy, Trinity Conn, Valérie F. Chamberland, Claire Lager, Nikolas Zuchowicz, Kathryn Lohr, Harvey Blackburn, Tali Vardi, Jennifer Moore, Tom Moore, Iliana B. Baums, Mark J. A. Vermeij, and Kristen L. Marhaver Biochemistry [Activation loop phosphorylaton of a non-RD receptor kinase initiates plant innate immune signaling]( Kyle W. Bender, Daniel Couto, Yasuhiro Kadota, Alberto P. Macho, Jan Sklenar, Paul Derbyshire, Marta Bjornson, Thomas A. DeFalco, Annalise Petriello, Maria Font Farre, Benjamin Schwessinger, Vardis Ntoukakis, Lena Stransfeld, Alexandra M. E. Jones, Frank L. H. Menke, and Cyril Zipfel Biophysics and Computational Biology [Geometry of gene regulatory dynamics]( David A. Rand, Archishman Raju, Meritxell Sáez, Francis Corson, and Eric D. Siggia [Identifying extracellular vesicle populations from single cells]( Jonas M. Nikoloff, Mario A. Saucedo-Espinosa, André Kling, and Petra S. Dittrich [The binding of the small heat-shock protein αB-crystallin to fibrils of α-synuclein is driven by entropic forces]( Tom Scheidt, Jacqueline A. Carozza, Carl C. Kolbe, Francesco A. Aprile, Olga Tkachenko, Mathias M. J. Bellaiche, Georg Meisl, Quentin A. E. Peter, Therese W. Herling, Samuel Ness, Marta Castellana-Cruz, Justin L. P. Benesch, Michele Vendruscolo, Christopher M. Dobson, Paolo Arosio, and Tuomas P. J. Knowles [Scaling of joint mass and metabolism fluctuations in in silico cell-laden spheroids]( Ermes Botte, Francesco Biagini, Chiara Magliaro, Andrea Rinaldo, Amos Maritan, and Arti Ahluwalia Cell Biology [TRIM28 is a transcriptional activator of the mutant TERT promoter in human bladder cancer]( Neeraj Agarwal, Sebastien Rinaldetti, Bassem B. Cheikh, Qiong Zhou, Evan P. Hass, Robert T. Jones, Molishree Joshi, Daniel V. LaBarbera, Simon R. V. Knott, Thomas R. Cech, and Dan Theodorescu Developmental Biology [Cannabinoid and planar cell polarity signaling converges to direct placentation]( Yeon Sun Kim, Yingju Li, Jia Yuan, Jean-Paul Borg, Xiaofei Sun, and Sudhansu K. Dey [Disabling de novo DNA methylation in embryonic stem cells allows an illegitimate fate trajectory]( Masaki Kinoshita, Meng Amy Li, Michael Barber, William Mansfield, Sabine Dietmann, and Austin Smith Environmental Sciences [Bluefin tuna reveal global patterns of mercury pollution and bioavailability in the world's oceans]( Chun-Mao Tseng, Shin-Jing Ang, Yi-Sheng Chen, Jen-Chieh Shiao, Carl H. Lamborg, Xiaoshuai He, and John R. Reinfelder [Marine Synechococcus picocyanobacteria: Light utilization across latitudes]( Christophe Six, Morgane Ratin, Dominique Marie, and Erwan Corre Evolution [The evolution of social parasitism in Formica ants revealed by a global phylogeny]( Marek L. Borowiec, Stefan P. Cover, and Christian Rabeling [Haplotype divergence supports long-term asexuality in the oribatid mite Oppiella nova]( Alexander Brandt, Patrick Tran Van, Christian Bluhm, Yoann Anselmetti, Zoé Dumas, Emeric Figuet, Clémentine M. François, Nicolas Galtier, Bastian Heimburger, Kamil S. Jaron, Marjorie Labédan, Mark Maraun, Darren J. Parker, Marc Robinson-Rechavi, Ina Schaefer, Paul Simion, Stefan Scheu, Tanja Schwander, and Jens Bast [Emergent RNA–RNA interactions can promote stability in a facultative phototrophic endosymbiosis]( Benjamin H. Jenkins, Finlay Maguire, Guy Leonard, Joshua D. Eaton, Steven West, Benjamin E. Housden, David S. Milner, and Thomas A. Richards Genetics [Restoring fertility in yeast hybrids: Breeding and quantitative genetics of beneficial traits]( Samina Naseeb, Federico Visinoni, Yue Hu, Alex J. Hinks Roberts, Agnieszka Maslowska, Thomas Walsh, Katherine A. Smart, Edward J. Louis, and Daniela Delneri [DNA damage–induced phosphorylation of CtIP at a conserved ATM/ATR site T855 promotes lymphomagenesis in mice]( Xiaobin S. Wang, Demis Menolfi, Foon Wu-Baer, Marco Fangazio, Stefanie N. Meyer, Zhengping Shao, Yunyue Wang, Yimeng Zhu, Brian J. Lee, Verna M. Estes, Olivia M. Cupo, Jean Gautier, Laura Pasqualucci, Riccardo Dalla-Favera, Richard Baer, and Shan Zha [A mechanism for Rad53 to couple leading- and lagging-strand DNA synthesis under replication stress in budding yeast]( Albert Serra-Cardona, Chuanhe Yu, Xinmin Zhang, Xu Hua, Yuan Yao, Jiaqi Zhou, Haiyun Gan, and Zhiguo Zhang Immunology and Inflammation [Interleukins 4 and 13 drive lipid abnormalities in skin cells through regulation of sex steroid hormone synthesis]( Chenlu Zhang, Mahendran Chinnappan, Courtney A. Prestwood, Marshall Edwards, Methinee Artami, Bonne M. Thompson, Kaitlyn M. Eckert, Goncalo Vale, Christos C. Zouboulis, Jeffrey G. McDonald, and Tamia A. Harris-Tryon [Coronavirus induces diabetic macrophage-mediated inflammation via SETDB2]( William J. Melvin, Christopher O. Audu, Frank M. Davis, Sriganesh B. Sharma, Amrita Joshi, Aaron DenDekker, Sonya Wolf, Emily Barrett, Kevin Mangum, Xiaofeng Zhou, Monica Bame, Alex Ruan, Andrea Obi, Steven L. Kunkel, Bethany B. Moore, and Katherine A. Gallagher [Efficacy and breadth of adjuvanted SARS-CoV-2 receptor-binding domain nanoparticle vaccine in macaques]( Hannah A. D. King, M. Gordon Joyce, Ines Lakhal-Naouar, Aslaa Ahmed, Camila Macedo Cincotta, Caroline Subra, Kristina K. Peachman, Holly R. Hack, Rita E. Chen, Paul V. Thomas, Wei-Hung Chen, Rajeshwer S. Sankhala, Agnes Hajduczki, Elizabeth J. Martinez, Caroline E. Peterson, William C. Chang, Misook Choe, Clayton Smith, Jarrett A. Headley, Hanne A. Elyard, Anthony Cook, Alexander Anderson, Kathryn McGuckin Wuertz, Ming Dong, Isabella Swafford, James B. Case, Jeffrey R. Currier, Kerri G. Lal, Mihret F. Amare, Vincent Dussupt, Sebastian Molnar, Sharon P. Daye, Xiankun Zeng, Erica K. Barkei, Kendra Alfson, Hilary M. Staples, Ricardo Carrion, Shelly J. Krebs, Dominic Paquin-Proulx, Nicos Karasavvas, Victoria R. Polonis, Linda L. Jagodzinski, Sandhya Vasan, Paul T. Scott, Yaoxing Huang, Manoj S. Nair, David D. Ho, Natalia de Val, Michael S. Diamond, Mark G. Lewis, Mangala Rao, Gary R. Matyas, Gregory D. Gromowski, Sheil a A. Peel, Nelson L. Michael, Kayvon Modjarrad, and Diane L. Bolton [Annexin A1 attenuates cardiac diastolic dysfunction in mice with inflammatory arthritis]( Jianmin Chen, Lucy V. Norling, Jose Garrido Mesa, Marina De Paula Silva, Sophie E. Burton, Chris Reutelingsperger, Mauro Perretti, and Dianne Cooper [TBK1 and IKKε act like an OFF switch to limit NLRP3 inflammasome pathway activation]( Fabian A. Fischer, Linda F. M. Mies, Sohaib Nizami, Eirini Pantazi, Sara Danielli, Benjamin Demarco, Michael Ohlmeyer, Michelle Sue Jann Lee, Cevayir Coban, Jonathan C. Kagan, Elena Di Daniel, and Jelena S. Bezbradica [Posttranslational modifications by ADAM10 shape myeloid antigen-presenting cell homeostasis in the splenic marginal zone]( Nathalie Diener, Jean-Fred Fontaine, Matthias Klein, Thomas Hieronymus, Florian Wanke, Florian C. Kurschus, Andreas Ludwig, Carl Ware, Paul Saftig, Tobias Bopp, Björn E. Clausen, and Ronald A. Backer [Aire regulates chromatin looping by evicting CTCF from domain boundaries and favoring accumulation of cohesin on superenhancers]( Kushagra Bansal, Daniel A. Michelson, Ricardo N. Ramirez, Aaron D. Viny, Ross L. Levine, Christophe Benoist, and Diane Mathis Medical Sciences [Therapeutic inhibition of USP9x-mediated Notch signaling in triple-negative breast cancer]( Arushi Jaiswal, Kiichi Murakami, Andrew Elia, Yukiko Shibahara, Susan J. Done, Stephen A. Wood, Nicholas J. Donato, Pamela S. Ohashi, and Michael Reedijk Microbiology [Evidence for biosurfactant-induced flow in corners and bacterial spreading in unsaturated porous media]( Judy Q. Yang, Joseph E. Sanfilippo, Niki Abbasi, Zemer Gitai, Bonnie L. Bassler, and Howard A. Stone [Koala retrovirus genetic diversity and transmission dynamics within captive koala populations]( Briony A. Joyce, Michaela D. J. Blyton, Stephen D. Johnston, Paul R. Young, and Keith J. Chappell Neuroscience [Facilitation of neural responses to targets moving against optic flow]( Sarah Nicholas and Karin Nordström [Early-life midazolam exposure persistently changes chromatin accessibility to impair adult hippocampal neurogenesis and cognition]( Hiroyoshi Doi, Taito Matsuda, Atsuhiko Sakai, Shuzo Matsubara, Sumio Hoka, Ken Yamaura, and Kinichi Nakashima Plant Biology [Click-to-lead design of a picomolar ABA receptor antagonist with potent activity in vivo]( Aditya S. Vaidya, Francis C. Peterson, James Eckhardt, Zenan Xing, Sang-Youl Park, Wim Dejonghe, Jun Takeuchi, Oded Pri-Tal, Julianna Faria, Dezi Elzinga, Brian F. Volkman, Yasushi Todoroki, Assaf Mosquna, Masanori Okamoto, and Sean R. Cutler Sustainability Science [Emerging forest–peatland bistability and resilience of European peatland carbon stores]( Ype van der Velde, Arnaud J. A. M. Temme, Jelmer J. Nijp, Maarten C. Braakhekke, George A. K. van Voorn, Stefan C. Dekker, A. Johannes Dolman, Jakob Wallinga, Kevin J. Devito, Nicholas Kettridge, Carl A. Mendoza, Lammert Kooistra, Merel B. Soons, and Adriaan J. Teuling [Integrated farming with intercropping increases food production while reducing environmental footprint]( Qiang Chai, Thomas Nemecek, Chang Liang, Cai Zhao, Aizhong Yu, Jeffrey A. Coulter, Yifan Wang, Falong Hu, Li Wang, Kadambot H. M. Siddique, and Yantai Gan --------------------------------------------------------------- Correction [Correction for Li et al., Structure of the Dietzia Mrp complex reveals molecular mechanism of this giant bacterial sodium proton pump]( --------------------------------------------------------------- SI Correction [Correction to Supporting Information for Weiler et al., mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy]( --------------------------------------------------------------- Retraction [Retraction for Shu et al., Signing at the beginning makes ethics salient and decreases dishonest self-reports in comparison to signing at the end]( [Cover] --------------------------------------------------------------- This message was sent to {EMAIL}. [Unsubscribe]( from or [edit]( your subscription for this service. Or by mail: Customer Service * 15575-A Los Gatos Blvd * Los Gatos, CA 95032 * U.S.A. Copyright © 2021 by the National Academy of Sciences