[PNAS] [PNAS announces](/cgi/adclick/?ad=55955&adclick=true&url=https%3A%2F%2Fwww.pnas.org%2Fpage%2Fupdates%2F%23jisc-agreement) Â [July 13, 2021; Vol. 118, No. 28](
) This Week in PNAS
[In This Issue]( This week's research highlights
--------------------------------------------------------------- Profile
[Profile of Claude Desplan](
Jennifer Viegas
The life and work of NAS members
--------------------------------------------------------------- Commentaries
[How to train your bacteriophage](
Adair L. Borges
[Antipsychotics, versatility in action](
Sidharth Mahapatra and Tiago Reis Marques
[Shining light on photosynthetic microbes and manganese-enriched rock varnish](
Valeria C. Culotta and Asia S. Wildeman
[A postreplicative C5-cytosine hypermodification triggered by bacteriophage methyltransferase and hydroxylase](
Tzu-Yu Chen and Wei-chen Chang --------------------------------------------------------------- Perspective
[Novel technologies for emission reduction complement conservation agriculture to achieve negative emissions from row-crop production](
Daniel L. Northrup, Bruno Basso, Michael Q. Wang, Cristine L. S. Morgan, and Philip N. Benfey --------------------------------------------------------------- Letters
[Do positive allosteric modulators (PAMs) of the MOR exert antinociception with reduced side effects under pathological conditions?](
Tao Zhuang, Yurong Ma, and Guisen Zhang
[Reply to Zhuang et al.: Potential side effects of positive allosteric modulators of the mu-opioid receptor](
John R. Traynor
[Still no evidence for transgenerational inheritance or absence of epigenetic reprogramming in the honey bee](
Fernando G. Soley
[Reply to Soley: DNA methylation marks are stably transferred across generations in honey bees](
Boris Yagound, Emily J. Remnant, Gabriele Buchmann, and Benjamin P. Oldroyd
[Reply to Linton: Perspectival interference up close](
Jorge Morales, Axel Bax, and Chaz Firestone --------------------------------------------------------------- Brief Report
[The intersection of DNA replication with antisense 3′ RNA processing in Arabidopsis FLC chromatin silencing](
Colette L. Baxter, Saša Šviković, Julian E. Sale, Caroline Dean, and Silvia Costa --------------------------------------------------------------- Physical Sciences
Applied Mathematics
[Tensor-tensor algebra for optimal representation and compression of multiway data](
Misha E. Kilmer, Lior Horesh, Haim Avron, and Elizabeth Newman Applied Physical Sciences
[An effective and efficient model of the near-field hydrodynamic interactions for active suspensions of bacteria](
Bokai Zhang, Premkumar Leishangthem, Yang Ding, and Xinliang Xu
[Biotransformation modulates the penetration of metallic nanomaterials across an artificial blood–brain barrier model](
Zhiling Guo, Peng Zhang, Swaroop Chakraborty, Andrew J Chetwynd, Fazel Abdolahpur Monikh, Christopher Stark, Hanene Ali-Boucetta, Sandra Wilson, Iseult Lynch, and Eugenia Valsami-Jones
[Entropic barrier of topologically immobilized DNA in hydrogels](
Kuo Chen and Murugappan Muthukumar Biophysics and Computational Biology
[Quantification and demonstration of the collective constriction-by-ratchet mechanism in the dynamin molecular motor](
Oleg M. Ganichkin, Renee Vancraenenbroeck, Gabriel Rosenblum, Hagen Hofmann, Alexander S. Mikhailov, Oliver Daumke, and Jeffrey K. Noel
[Modeling links softening of myelin and spectrin scaffolds of axons after a concussion to increased vulnerability to repeated injuries](
Aayush Kant, Victoria E. Johnson, John D. Arena, Jean-Pierre Dollé, Douglas H. Smith, and Vivek B. Shenoy Chemistry
[Identification of simple arylfluorosulfates as potent agents against resistant bacteria](
Jiong Zhang, Xiangxiang Zhao, John R. Cappiello, Yi Yang, Yunfei Cheng, Guang Liu, Wenjing Fang, Yinzhu Luo, Yu Zhang, Jiajia Dong, Lixin Zhang, and K. Barry Sharpless
[1,2-Difunctionalized bicyclo[1.1.1]pentanes: Long–sought-after mimetics for ortho/meta-substituted arenes](
Jin-Xin Zhao, Yu-Xuan Chang, Chi He, Benjamin J. Burke, Michael R. Collins, Matthew Del Bel, Jeff Elleraas, Gary M. Gallego, T. Patrick Montgomery, James J. Mousseau, Sajiv K. Nair, Matthew A. Perry, Jillian E. Spangler, Julien C. Vantourout, and Phil S. Baran
[Rapid diagnosis and tumor margin assessment during pancreatic cancer surgery with the MasSpec Pen technology](
Mary E. King, Jialing Zhang, John Q. Lin, Kyana Y. Garza, Rachel J. DeHoog, Clara L. Feider, Alena Bensussan, Marta Sans, Anna Krieger, Sunil Badal, Michael F. Keating, Spencer Woody, Sadhna Dhingra, Wendong Yu, Christopher Pirko, Kirtan A. Brahmbhatt, George Van Buren, William E. Fisher, James Suliburk, and Livia S. Eberlin Earth, Atmospheric, and Planetary Sciences
[Observing the subglacial hydrology network and its dynamics with a dense seismic array](
Ugo Nanni, Florent Gimbert, Philippe Roux, and Albanne Lecointre Engineering
[Modeling links softening of myelin and spectrin scaffolds of axons after a concussion to increased vulnerability to repeated injuries](
Aayush Kant, Victoria E. Johnson, John D. Arena, Jean-Pierre Dollé, Douglas H. Smith, and Vivek B. Shenoy
[A self-powered implantable and bioresorbable electrostimulation device for biofeedback bone fracture healing](
Guang Yao, Lei Kang, Cuicui Li, Sihong Chen, Qian Wang, Junzhe Yang, Yin Long, Jun Li, Kangning Zhao, Weina Xu, Weibo Cai, Yuan Lin, and Xudong Wang
[Hydrogel–mesh composite for wound closure](
Yang Gao, Xiuyuan Han, Jiaojiao Chen, Yudong Pan, Meng Yang, Linhe Lu, Jian Yang, Zhigang Suo, and Tongqing Lu Environmental Sciences
[Birds use individually consistent temperature cues to time their migration departure](
Robert J. Burnside, Daniel Salliss, Nigel J. Collar, and Paul M. Dolman Mathematics
[From linear to metric functional analysis](
Anders Karlsson Physics
[Pressure-induced high-temperature superconductivity retained without pressure in FeSe single crystals](
Liangzi Deng, Trevor Bontke, Rabin Dahal, Yu Xie, Bin Gao, Xue Li, Ketao Yin, Melissa Gooch, Donald Rolston, Tong Chen, Zheng Wu, Yanming Ma, Pengcheng Dai, and Ching-Wu Chu Sustainability Science
[Integrated assessment modeling reveals near-channel management as cost-effective to improve water quality in agricultural watersheds](
Amy T. Hansen, Todd Campbell, Se Jong Cho, Jonathan A. Czuba, Brent J. Dalzell, Christine L. Dolph, Peter L. Hawthorne, Sergey Rabotyagov, Zhengxin Lang, Karthik Kumarasamy, Patrick Belmont, Jacques C. Finlay, Efi Foufoula-Georgiou, Karen B. Gran, Catherine L. Kling, and Peter Wilcock --------------------------------------------------------------- Social Sciences
Anthropology
[Historic and bioarchaeological evidence supports late onset of post-Columbian epidemics in Native California](
Terry L. Jones, Al W. Schwitalla, Marin A. Pilloud, John R. Johnson, Richard R. Paine, and Brian F. Codding Economic Sciences
[Thirty-five years later: Long-term effects of the Matlab maternal and child health/family planning program on older women’s well-being](
Tania Barham, Brachel Champion, Andrew D. Foster, Jena D. Hamadani, Warren C. Jochem, Gisella Kagy, Randall Kuhn, Jane Menken, Abdur Razzaque, Elisabeth Dowling Root, and Patrick S. Turner Psychological and Cognitive Sciences
[Shifting gradients of macroscale cortical organization mark the transition from childhood to adolescence](
Hao-Ming Dong, Daniel S. Margulies, Xi-Nian Zuo, and Avram J. Holmes Social Sciences
[Thirty-five years later: Long-term effects of the Matlab maternal and child health/family planning program on older women’s well-being](
Tania Barham, Brachel Champion, Andrew D. Foster, Jena D. Hamadani, Warren C. Jochem, Gisella Kagy, Randall Kuhn, Jane Menken, Abdur Razzaque, Elisabeth Dowling Root, and Patrick S. Turner Sustainability Science
[Integrated assessment modeling reveals near-channel management as cost-effective to improve water quality in agricultural watersheds](
Amy T. Hansen, Todd Campbell, Se Jong Cho, Jonathan A. Czuba, Brent J. Dalzell, Christine L. Dolph, Peter L. Hawthorne, Sergey Rabotyagov, Zhengxin Lang, Karthik Kumarasamy, Patrick Belmont, Jacques C. Finlay, Efi Foufoula-Georgiou, Karen B. Gran, Catherine L. Kling, and Peter Wilcock --------------------------------------------------------------- Biological Sciences
Applied Biological Sciences
[A self-powered implantable and bioresorbable electrostimulation device for biofeedback bone fracture healing](
Guang Yao, Lei Kang, Cuicui Li, Sihong Chen, Qian Wang, Junzhe Yang, Yin Long, Jun Li, Kangning Zhao, Weina Xu, Weibo Cai, Yuan Lin, and Xudong Wang
[DNAse-dependent, NET-independent pathway of thrombus formation in vivo](
Estelle Carminita, Lydie Crescence, Nicolas Brouilly, Alexandre Altié, Laurence Panicot-Dubois, and Christophe Dubois Biophysics and Computational Biology
[Quantification and demonstration of the collective constriction-by-ratchet mechanism in the dynamin molecular motor](
Oleg M. Ganichkin, Renee Vancraenenbroeck, Gabriel Rosenblum, Hagen Hofmann, Alexander S. Mikhailov, Oliver Daumke, and Jeffrey K. Noel
[Regulation and drug modulation of a voltage-gated sodium channel: Pivotal role of the S4–S5 linker in activation and slow inactivation](
Jinglei Xiao, Vasyl Bondarenko, Yali Wang, Antonio Suma, Marta Wells, Qiang Chen, Tommy Tillman, Yan Luo, Buwei Yu, William P. Dailey, Roderic Eckenhoff, Pei Tang, Vincenzo Carnevale, Michael L. Klein, and Yan Xu Cell Biology
[p53 deficiency induces MTHFD2 transcription to promote cell proliferation and restrain DNA damage](
Gen Li, Jun Wu, Le Li, and Peng Jiang
[The GAS6-AXL signaling pathway triggers actin remodeling that drives membrane ruffling, macropinocytosis, and cancer-cell invasion](
Daria Zdżalik-Bielecka, Agata Poświata, Kamila Kozik, Kamil Jastrzębski, Kay Oliver Schink, Marta Brewińska-Olchowik, Katarzyna Piwocka, Harald Stenmark, and Marta Miączyńska
[Sufu negatively regulates both initiations of centrosome duplication and DNA replication](
Tenghan Zhuang, Boyan Zhang, Yihong Song, Fan Huang, Wangfei Chi, Guangwei Xin, Ziyu Zhang, Steven Y. Cheng, Qing Jiang, and Chuanmao Zhang Developmental Biology
[Neural specification, targeting, and circuit formation during visual system assembly](
Jennifer Malin and Claude Desplan
[Ciliopathy genes are required for apical secretion of Cochlin, an otolith crystallization factor](
Eleni Leventea, Zhou Zhu, Xiaoming Fang, Yulia Nikolaeva, Eleanor Markham, Robert A. Hirst, Fredericus J. M. van Eeden, and Jarema J. Malicki
[Live imaging of remyelination in the adult mouse corpus callosum](
Sara Bottes and Sebastian Jessberger Ecology
[Birds use individually consistent temperature cues to time their migration departure](
Robert J. Burnside, Daniel Salliss, Nigel J. Collar, and Paul M. Dolman
[Ecology of the Anthropocene signals hope for consciously managing the planetary ecosystem](
Clarence Lehman, Shelby Loberg, Michael Wilson, and Eville Gorham
[Negative effects of nitrogen override positive effects of phosphorus on grassland legumes worldwide](
Pedro M. Tognetti, Suzanne M. Prober, Selene Báez, Enrique J. Chaneton, Jennifer Firn, Anita C. Risch, Martin Schuetz, Anna K. Simonsen, Laura Yahdjian, Elizabeth T. Borer, Eric W. Seabloom, Carlos Alberto Arnillas, Jonathan D. Bakker, Cynthia S. Brown, Marc W. Cadotte, Maria C. Caldeira, Pedro Daleo, John M. Dwyer, Philip A. Fay, Laureano A. Gherardi, Nicole Hagenah, Yann Hautier, Kimberly J. Komatsu, Rebecca L. McCulley, Jodi N. Price, Rachel J. Standish, Carly J. Stevens, Peter D. Wragg, and Mahesh Sankaran
[Heterogeneous selection on exploration behavior within and among West European populations of a passerine bird](
Alexia Mouchet, Ella F. Cole, Erik Matthysen, Marion Nicolaus, John L. Quinn, Allison M. Roth, Joost M. Tinbergen, Kees van Oers, Thijs van Overveld, and Niels J. Dingemanse
[Direct evidence of a prey depletion “halo” surrounding a pelagic predator colony](
Sam B. Weber, Andrew J. Richardson, Judith Brown, Mark Bolton, Bethany L. Clark, Brendan J. Godley, Eliza Leat, Steffen Oppel, Laura Shearer, Karline E. R. Soetaert, Nicola Weber, and Annette C. Broderick Evolution
[Sex-specific ornament evolution is a consistent feature of climatic adaptation across space and time in dragonflies](
Michael P. Moore, Kaitlyn Hersch, Chanont Sricharoen, Sarah Lee, Caitlin Reice, Paul Rice, Sophie Kronick, Kim A. Medley, and Kasey D. Fowler-Finn Genetics
[A platform utilizing Drosophila ovulation for nonhormonal contraceptive screening](
Kewa Jiang, Jiyang Zhang, Yuping Huang, Yingzheng Wang, Shuo Xiao, M. Kyle Hadden, Teresa K. Woodruff, and Jianjun Sun
[Thousands of induced germline mutations affecting immune cells identified by automated meiotic mapping coupled with machine learning](
Darui Xu, Stephen Lyon, Chun Hui Bu, Sara Hildebrand, Jin Huk Choi, Xue Zhong, Aijie Liu, Emre E. Turer, Zhao Zhang, Jamie Russell, Sara Ludwig, Elena Mahrt, Evan Nair-Gill, Hexin Shi, Ying Wang, Duanwu Zhang, Tao Yue, Kuan-wen Wang, Jeffrey A. SoRelle, Lijing Su, Takuma Misawa, William McAlpine, Lei Sun, Jianhui Wang, Xiaoming Zhan, Mihwa Choi, Roxana Farokhnia, Andrew Sakla, Sara Schneider, Hannah Coco, Gabrielle Coolbaugh, Braden Hayse, Sara Mazal, Dawson Medler, Brandon Nguyen, Edward Rodriguez, Andrew Wadley, Miao Tang, Xiaohong Li, Priscilla Anderton, Katie Keller, Amanda Press, Lindsay Scott, Jiexia Quan, Sydney Cooper, Tiffany Collie, Baifang Qin, Jennifer Cardin, Rochelle Simpson, Meron Tadesse, Qihua Sun, Carol A. Wise, Jonathan J. Rios, Eva Marie Y. Moresco, and Bruce Beutler Immunology and Inflammation
[Landscape of innate lymphoid cells in human head and neck cancer reveals divergent NK cell states in the tumor microenvironment](
Uriel Y. Moreno-Nieves, Joshua K. Tay, Saumyaa Saumyaa, Nina B. Horowitz, June Ho Shin, Imran A. Mohammad, Bogdan Luca, David C. Mundy, Gunsagar S. Gulati, Nikita Bedi, Serena Chang, Chen Chen, Michael J. Kaplan, Eben L. Rosenthal, F. Christopher Holsinger, Vasu Divi, Fred M. Baik, Davud B. Sirjani, Andrew J. Gentles, Aaron M. Newman, Aharon G. Freud, and John B. Sunwoo
[HIPK2 phosphorylates HDAC3 for NF-ÎşB acetylation to ameliorate colitis-associated colorectal carcinoma and sepsis](
Fang Zhang, Linlin Qi, Qiuyun Feng, Baokai Zhang, Xiangyue Li, Chang Liu, Weiyun Li, Qiaojie Liu, Dan Yang, Yue Yin, Chao Peng, Han Wu, Zhao-Hui Tang, Xi Zhou, Zou Xiang, Zhijiang Zhang, Hongyan Wang, and Bin Wei
[Hypoimmune induced pluripotent stem cell–derived cell therapeutics treat cardiovascular and pulmonary diseases in immunocompetent allogeneic mice](
Tobias Deuse, Grigol Tediashvili, Xiaomeng Hu, Alessia Gravina, Annika Tamenang, Dong Wang, Andrew Connolly, Christian Mueller, Beñat Mallavia, Mark R. Looney, Malik Alawi, Lewis L. Lanier, and Sonja Schrepfer
[RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signaling](
Kaiwen W. Chen, Benjamin Demarco, Saray Ramos, Rosalie Heilig, Michiel Goris, James P. Grayczyk, Charles-Antoine Assenmacher, Enrico Radaelli, Leonel D. Joannas, Jorge Henao-Mejia, Fabienne Tacchini-Cottier, Igor E. Brodsky, and Petr Broz Medical Sciences
[Hydrogel–mesh composite for wound closure](
Yang Gao, Xiuyuan Han, Jiaojiao Chen, Yudong Pan, Meng Yang, Linhe Lu, Jian Yang, Zhigang Suo, and Tongqing Lu
[Rapid diagnosis and tumor margin assessment during pancreatic cancer surgery with the MasSpec Pen technology](
Mary E. King, Jialing Zhang, John Q. Lin, Kyana Y. Garza, Rachel J. DeHoog, Clara L. Feider, Alena Bensussan, Marta Sans, Anna Krieger, Sunil Badal, Michael F. Keating, Spencer Woody, Sadhna Dhingra, Wendong Yu, Christopher Pirko, Kirtan A. Brahmbhatt, George Van Buren, William E. Fisher, James Suliburk, and Livia S. Eberlin
[Large age shifts in HIV-1 incidence patterns in KwaZulu-Natal, South Africa](
Adam Akullian, Alain Vandormael, Joel C. Miller, Anna Bershteyn, Edward Wenger, Diego Cuadros, Dickman Gareta, Till Bärnighausen, Kobus Herbst, and Frank Tanser
[A conserved epitope III on hepatitis C virus E2 protein has alternate conformations facilitating cell binding or virus neutralization](
Lu Deng, Nancy Hernandez, Lilin Zhong, David D. Holcomb, Hailing Yan, Maria Luisa Virata, Sreya Tarafdar, Yanqun Xu, Yong He, Evi Struble, Harvey J. Alter, and Pei Zhang
[Pan-African evolution of within- and between-country COVID-19 dynamics](
Paddy Ssentongo, Claudio Fronterre, Andrew Geronimo, Steven J. Greybush, Pamela K. Mbabazi, Joseph Muvawala, Sarah B. Nahalamba, Philip O. Omadi, Bernard T. Opar, Shamim A. Sinnar, Yan Wang, Andrew J. Whalen, Leonhard Held, Christopher Jewell, Abraham J. B. Muwanguzi, Helen Greatrex, Michael M. Norton, Peter J. Diggle, and Steven J. Schiff Microbiology
[Identification of simple arylfluorosulfates as potent agents against resistant bacteria](
Jiong Zhang, Xiangxiang Zhao, John R. Cappiello, Yi Yang, Yunfei Cheng, Guang Liu, Wenjing Fang, Yinzhu Luo, Yu Zhang, Jiajia Dong, Lixin Zhang, and K. Barry Sharpless
[Immunogenicity and efficacy of the COVID-19 candidate vector vaccine MVA-SARS-2-S in preclinical vaccination](
Alina Tscherne, Jan Hendrik Schwarz, Cornelius Rohde, Alexandra Kupke, Georgia Kalodimou, Leonard Limpinsel, Nisreen M. A. Okba, Berislav Bošnjak, Inga Sandrock, Ivan Odak, Sandro Halwe, Lucie Sauerhering, Katrin Brosinski, Nan Liangliang, Elke Duell, Sylvia Jany, Astrid Freudenstein, Jörg Schmidt, Anke Werner, Michelle Gellhorn Serra, Michael Klüver, Wolfgang Guggemos, Michael Seilmaier, Clemens-Martin Wendtner, Reinhold Förster, Bart L. Haagmans, Stephan Becker, Gerd Sutter, and Asisa Volz
[Let-7b-5p in vesicles secreted by human airway cells reduces biofilm formation and increases antibiotic sensitivity of P. aeruginosa](
Katja Koeppen, Amanda Nymon, Roxanna Barnaby, Laura Bashor, Zhongyou Li, Thomas H. Hampton, Amanda E. Liefeld, Fred W. Kolling, Ian S. LaCroix, Scott A. Gerber, Deborah A. Hogan, Swetha Kasetty, Carey D. Nadell, and Bruce A. Stanton
[Defensive hypervariable regions confer superinfection exclusion in microviruses](
Paul C. Kirchberger, Zachary A. Martinez, Landry J. Luker, and Howard Ochman
[Temporal compartmentalization of viral infection in bacterial cells](
Audrey Labarde, Lina Jakutyte, Cyrille Billaudeau, Beatrix Fauler, Maria LĂłpez-Sanz, Prishila Ponien, Eric Jacquet, Thorsten Mielke, Silvia Ayora, Rut Carballido-LĂłpez, and Paulo Tavares Neuroscience
[Shifting gradients of macroscale cortical organization mark the transition from childhood to adolescence](
Hao-Ming Dong, Daniel S. Margulies, Xi-Nian Zuo, and Avram J. Holmes
[Skin sodium is increased in male patients with multiple sclerosis and related animal models](
Konstantin Huhn, Peter Linz, Franziska Pemsel, Bernhard Michalke, Stefan Seyferth, Christoph Kopp, Mohammad Anwar Chaudri, Veit Rothhammer, Arnd Dörfler, Michael Uder, Armin M. Nagel, Dominik N. Müller, Anne Waschbisch, De-Hyung Lee, Tobias Bäuerle, Ralf A. Linker, and Stefanie Haase
[PIEZO2 mediates ultrasonic hearing via cochlear outer hair cells in mice](
Jie Li, Shuang Liu, Chenmeng Song, Qun Hu, Zhikai Zhao, Tuantuan Deng, Yi Wang, Tong Zhu, Linzhi Zou, Shufeng Wang, Jiaofeng Chen, Lian Liu, Hanqing Hou, Kexin Yuan, Hairong Zheng, Zhiyong Liu, Xiaowei Chen, Wenzhi Sun, Bailong Xiao, and Wei Xiong
[MAGUKs are essential, but redundant, in long-term potentiation](
Xiumin Chen, Yuko Fukata, Masaki Fukata, and Roger A. Nicoll
[Pain and itch processing by subpopulations of molecularly diverse spinal and trigeminal projection neurons](
Racheli Wercberger, Joao M. Braz, Jarret A. Weinrich, and Allan I. Basbaum
[VLM catecholaminergic neurons control tumor growth by regulating CD8+ T cells](
Ze Zhang, Yehua Li, Xueyuan Lv, Linlin Zhao, and Xiaodong Wang
[Separation of presynaptic Cav2 and Cav1 channel function in synaptic vesicle exo- and endocytosis by the membrane anchored Ca2+ pump PMCA](
Niklas Krick, Stefanie Ryglewski, Aylin Pichler, Arthur Bikbaev, Torsten Götz, Oliver Kobler, Martin Heine, Ulrich Thomas, and Carsten Duch
[Clock proteins regulate spatiotemporal organization of clock genes to control circadian rhythms](
Yangbo Xiao, Ye Yuan, Mariana Jimenez, Neeraj Soni, and Swathi Yadlapalli
[Agonist of growth hormone–releasing hormone enhances retinal ganglion cell protection induced by macrophages after optic nerve injury](
Ling-Ping Cen, Tsz Kin Ng, Jia-Jian Liang, Ciyan Xu, Xi Zhuang, Yu-Fen Liu, Shao-Lang Chen, Yanxuan Xu, Qichen Yang, Xiang-Ling Yuan, Yong Jie Qin, Sun On Chan, Haoyu Chen, Mingzhi Zhang, Andrew V. Schally, and Chi Pui Pang Pharmacology
[Proton-gated coincidence detection is a common feature of GPCR signaling](
Nicholas J. Kapolka, Jacob B. Rowe, Geoffrey J. Taghon, William M. Morgan, Corin R. O’Shea, and Daniel G. Isom Physiology
[Prednisolone rescues Duchenne muscular dystrophy phenotypes in human pluripotent stem cell–derived skeletal muscle in vitro](
Ziad Al Tanoury, John F. Zimmerman, Jyoti Rao, Daniel Sieiro, Harold M. McNamara, Thomas Cherrier, Alejandra RodrĂguez-delaRosa, Aurore Hick-Colin, Fanny Bousson, Charlotte Fugier-Schmucker, Fabio Marchiano, Bianca Habermann, JĂ©rome Chal, Alexander P. Nesmith, Svetlana Gapon, Erica Wagner, Vandana A. Gupta, Rhonda Bassel-Duby, Eric N. Olson, Adam E. Cohen, Kevin Kit Parker, and Olivier PourquiĂ©
[Bidirectional flow of the funny current (If) during the pacemaking cycle in murine sinoatrial node myocytes](
Colin H. Peters, Pin W. Liu, Stefano Morotti, Stephanie C. Gantz, Eleonora Grandi, Bruce P. Bean, and Catherine Proenza Sustainability Science
[Ecology of the Anthropocene signals hope for consciously managing the planetary ecosystem](
Clarence Lehman, Shelby Loberg, Michael Wilson, and Eville Gorham
[Negative effects of nitrogen override positive effects of phosphorus on grassland legumes worldwide](
Pedro M. Tognetti, Suzanne M. Prober, Selene Báez, Enrique J. Chaneton, Jennifer Firn, Anita C. Risch, Martin Schuetz, Anna K. Simonsen, Laura Yahdjian, Elizabeth T. Borer, Eric W. Seabloom, Carlos Alberto Arnillas, Jonathan D. Bakker, Cynthia S. Brown, Marc W. Cadotte, Maria C. Caldeira, Pedro Daleo, John M. Dwyer, Philip A. Fay, Laureano A. Gherardi, Nicole Hagenah, Yann Hautier, Kimberly J. Komatsu, Rebecca L. McCulley, Jodi N. Price, Rachel J. Standish, Carly J. Stevens, Peter D. Wragg, and Mahesh Sankaran --------------------------------------------------------------- Correction
[Correction for Gonzales et al., Subregion-specific rules govern the distribution of neuronal immediate-early gene induction]( [Cover] --------------------------------------------------------------- This message was sent to {EMAIL}. [Unsubscribe]( from or [edit]( your subscription for this service.
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