PNAS Table of Contents for May 25, 2021; Vol. 118, No. 21 is now complete

[PNAS] [NAS launches new open access journal PNAS Nexus. Learn more.](/cgi/adclick/?ad=55858&adclick=true&url=https%3A%2F%2Fwww.pnas.org%2Fpage%2Fupdates%2F%23announcing-pnas-nexus)   [May 25, 2021; Vol. 118, No. 21]( ) This Week in PNAS [In This Issue]( This week's research highlights --------------------------------------------------------------- Core Concepts [Core Concept: Herd immunity is an important—and often misunderstood—public health phenomenon]( Amy McDermott A brief introduction to emerging topics in science --------------------------------------------------------------- Retrospective [David W. Schindler (1940–2021): Trailblazing scientist and advocate for the environment]( Karen A. Kidd, William F. Donahue, Erin N. Kelly, Peter R. Leavitt, and Heidi Swanson --------------------------------------------------------------- Profile [Profile of Scott Edwards]( Tinsley H. Davis The life and work of NAS members --------------------------------------------------------------- Commentaries [From equality to hierarchy]( Simon DeDeo and Elizabeth A. Hobson [The intricate relationship between transcription and translation]( Michael W. Webster and Albert Weixlbaumer [PIP2 as the “coin of the realm” for neurovascular coupling]( Scott Earley and David Kleinfeld [Disengagement of light responses in Arabidopsis by localized developmental factors]( Meng Chen --------------------------------------------------------------- Perspectives [A strategy to improve expert technology forecasts]( Tamara Savage, Alex Davis, Baruch Fischhoff, and M. Granger Morgan [Old vaccines for new infections: Exploiting innate immunity to control COVID-19 and prevent future pandemics]( Konstantin Chumakov, Michael S. Avidan, Christine S. Benn, Stefano M. Bertozzi, Lawrence Blatt, Angela Y. Chang, Dean T. Jamison, Shabaana A. Khader, Shyam Kottilil, Mihai G. Netea, Annie Sparrow, and Robert C. Gallo --------------------------------------------------------------- Letters [Null models for gene enrichment in plasmids]( Liam P. Shaw [Reply to Shaw: Challenges for enrichment analysis of AMR gene-bearing plasmids]( You Che, Yu Yang, Xiaoqing Xu, Karel Břinda, Martin F. Polz, William P. Hanage, and Tong Zhang [COVID-19 induces lower levels of IL-8, IL-10, and MCP-1 than other acute CRS-inducing diseases]( Liang Cheng, Zijun Zhu, Chao Wang, Ping Wang, Yongqun Oliver He, and Xue Zhang [Reply to Cheng et al.: COVID-19 induces lower extent of cytokines, but damages vascular endothelium by IL-6 signaling]( Sujin Kang, Toshio Tanaka, Hitomi Inoue, Chikako Ono, Shoji Hashimoto, Yoshiyuki Kioi, Hisatake Matsumoto, Hiroshi Matsuura, Tsunehiro Matsubara, Kentaro Shimizu, Hiroshi Ogura, Yoshiharu Matsuura, and Tadamitsu Kishimoto --------------------------------------------------------------- Brief Reports [Permafrost carbon feedbacks threaten global climate goals]( Susan M. Natali, John P. Holdren, Brendan M. Rogers, Rachael Treharne, Philip B. Duffy, Rafe Pomerance, and Erin MacDonald [Reducing mask resistance among White evangelical Christians with value-consistent messages]( Stephanie L. DeMora, Jennifer L. Merolla, Brian Newman, and Elizabeth J. Zechmeister --------------------------------------------------------------- Physical Sciences Applied Mathematics [Scaling up real networks by geometric branching growth]( Muhua Zheng, Guillermo García-Pérez, Marián Boguñá, and M. Ángeles Serrano [Machine learning–accelerated computational fluid dynamics]( Dmitrii Kochkov, Jamie A. Smith, Ayya Alieva, Qing Wang, Michael P. Brenner, and Stephan Hoyer Applied Physical Sciences [Optical computation of a spin glass dynamics with tunable complexity]( M. Leonetti, E. Hörmann, L. Leuzzi, G. Parisi, and G. Ruocco [Topological clustering of multilayer networks]( Monisha Yuvaraj, Asim K. Dey, Vyacheslav Lyubchich, Yulia R. Gel, and H. Vincent Poor [Moving beyond the constraints of chemistry via crystal structure discovery with isotropic multiwell pair potentials]( Julia Dshemuchadse, Pablo F. Damasceno, Carolyn L. Phillips, Michael Engel, and Sharon C. Glotzer [Oligomodal metamaterials with multifunctional mechanics]( Aleksi Bossart, David M. J. Dykstra, Jop van der Laan, and Corentin Coulais [Random heterogeneity outperforms design in network synchronization]( Yuanzhao Zhang, Jorge L. Ocampo-Espindola, István Z. Kiss, and Adilson E. Motter [Microchemomechanical devices using DNA hybridization]( Guolong Zhu, Mark Hannel, Ruojie Sha, Feng Zhou, Matan Yah Ben Zion, Yin Zhang, Kyle Bishop, David Grier, Nadrian Seeman, and Paul Chaikin [Flexoelectricity in soft elastomers and the molecular mechanisms underpinning the design and emergence of giant flexoelectricity]( Matthew Grasinger, Kosar Mozaffari, and Pradeep Sharma [Terahertz detection based on nonlinear Hall effect without magnetic field]( Yang Zhang and Liang Fu [An additive algorithm for origami design]( Levi H. Dudte, Gary P. T. Choi, and L. Mahadevan Biophysics and Computational Biology [Inoculum effect of antimicrobial peptides]( Maria Rosa Loffredo, Filippo Savini, Sara Bobone, Bruno Casciaro, Henrik Franzyk, Maria Luisa Mangoni, and Lorenzo Stella [Hydrodynamic shear dissipation and transmission in lipid bilayers]( Guillermo J. Amador, Dennis van Dijk, Roland Kieffer, Marie-Eve Aubin-Tam, and Daniel Tam [Short hydrogen bonds enhance nonaromatic protein-related fluorescence]( Amberley D. Stephens, Muhammad Nawaz Qaisrani, Michael T. Ruggiero, Gonzalo Díaz Mirón, Uriel N. Morzan, Mariano C. González Lebrero, Saul T. E. Jones, Emiliano Poli, Andrew D. Bond, Philippa J. Woodhams, Elyse M. Kleist, Luca Grisanti, Ralph Gebauer, J. Axel Zeitler, Dan Credgington, Ali Hassanali, and Gabriele S. Kaminski Schierle [Impact of an alpha helix and a cysteine–cysteine disulfide bond on the resistance of bacterial adhesion pili to stress]( Joseph L. Baker, Tobias Dahlberg, Esther Bullitt, and Magnus Andersson [A biophysical limit for quorum sensing in biofilms]( Avaneesh V. Narla, David Bruce Borenstein, and Ned S. Wingreen Chemistry [Background-free dual-mode optical and 13C magnetic resonance imaging in diamond particles]( Xudong Lv, Jeffrey H. Walton, Emanuel Druga, Fei Wang, Alessandra Aguilar, Tommy McKnelly, Raffi Nazaryan, Fanglin Linda Liu, Lan Wu, Olga Shenderova, Daniel B. Vigneron, Carlos A. Meriles, Jeffrey A. Reimer, Alexander Pines, and Ashok Ajoy [High energy density and extremely stable supercapacitors based on carbon aerogels with 100% capacitance retention up to 65,000 cycles]( Yu Ma, Ding Chen, Zhi Fang, Yapeng Zheng, Weijun Li, Shang Xu, Xianlu Lu, Gang Shao, Qiao Liu, and Weiyou Yang [Thermal resistance effect on anomalous diffusion of molecules under confinement]( Jiamin Yuan, Zhiqiang Liu, Yimo Wu, Jingfeng Han, Xiaomin Tang, Chengbin Li, Wei Chen, Xianfeng Yi, Jian Zhou, Rajamani Krishna, German Sastre, and Anmin Zheng [Short-lived intermediate in N2O generation by P450 NO reductase captured by time-resolved IR spectroscopy and XFEL crystallography]( Takashi Nomura, Tetsunari Kimura, Yusuke Kanematsu, Daichi Yamada, Keitaro Yamashita, Kunio Hirata, Go Ueno, Hironori Murakami, Tamao Hisano, Raika Yamagiwa, Hanae Takeda, Chai Gopalasingam, Ryota Kousaka, Sachiko Yanagisawa, Osami Shoji, Takashi Kumasaka, Masaki Yamamoto, Yu Takano, Hiroshi Sugimoto, Takehiko Tosha, Minoru Kubo, and Yoshitsugu Shiro Earth, Atmospheric, and Planetary Sciences [Coastal eutrophication drives acidification, oxygen loss, and ecosystem change in a major oceanic upwelling system]( Faycal Kessouri, James C. McWilliams, Daniele Bianchi, Martha Sutula, Lionel Renault, Curtis Deutsch, Richard A. Feely, Karen McLaughlin, Minna Ho, Evan M. Howard, Nina Bednaršek, Pierre Damien, Jeroen Molemaker, and Stephen B. Weisberg [Arctic soil patterns analogous to fluid instabilities]( Rachel C. Glade, Michael M. Fratkin, Mehdi Pouragha, Ali Seiphoori, and Joel C. Rowland [Critical slowing down suggests that the western Greenland Ice Sheet is close to a tipping point]( Niklas Boers and Martin Rypdal [Coal fly ash is a major carbon flux in the Chang Jiang (Yangtze River) basin]( Gen K. Li, Woodward W. Fischer, Michael P. Lamb, A. Joshua West, Ting Zhang, Valier Galy, Xingchen Tony Wang, Shilei Li, Hongrui Qiu, Gaojun Li, Liang Zhao, Jun Chen, and Junfeng Ji [Global declines in coral reef calcium carbonate production under ocean acidification and warming]( Christopher E. Cornwall, Steeve Comeau, Niklas A. Kornder, Chris T. Perry, Ruben van Hooidonk, Thomas M. DeCarlo, Morgan S. Pratchett, Kristen D. Anderson, Nicola Browne, Robert Carpenter, Guillermo Diaz-Pulido, Juan P. D’Olivo, Steve S. Doo, Joana Figueiredo, Sofia A. V. Fortunato, Emma Kennedy, Coulson A. Lantz, Malcolm T. McCulloch, Manuel González-Rivero, Verena Schoepf, Scott G. Smithers, and Ryan J. Lowe Engineering [Continuous learning of emergent behavior in robotic matter]( Giorgio Oliveri, Lucas C. van Laake, Cesare Carissimo, Clara Miette, and Johannes T. B. Overvelde [Evolutionary design of magnetic soft continuum robots]( Liu Wang, Dongchang Zheng, Pablo Harker, Aman B. Patel, Chuan Fei Guo, and Xuanhe Zhao Physics [Phase space transport in the interaction between shocks and plasma turbulence]( Domenico Trotta, Francesco Valentini, David Burgess, and Sergio Servidio Statistics [A kernel-modulated SIR model for Covid-19 contagious spread from county to continent]( Xiaolong Geng, Gabriel G. Katul, Firas Gerges, Elie Bou-Zeid, Hani Nassif, and Michel C. Boufadel [Quantifying collective intelligence in human groups]( Christoph Riedl, Young Ji Kim, Pranav Gupta, Thomas W. Malone, and Anita Williams Woolley [Nonparametric coalescent inference of mutation spectrum history and demography]( William S. DeWitt, Kameron Decker Harris, Aaron P. Ragsdale, and Kelley Harris --------------------------------------------------------------- Social Sciences Anthropology [Plant species richness at archaeological sites suggests ecological legacy of Indigenous subsistence on the Colorado Plateau]( Bruce M. Pavlik, Lisbeth A. Louderback, Kenneth B. Vernon, Peter M. Yaworsky, Cynthia Wilson, Arnold Clifford, and Brian F. Codding Economic Sciences [Scaling up real networks by geometric branching growth]( Muhua Zheng, Guillermo García-Pérez, Marián Boguñá, and M. Ángeles Serrano [Gender roles produce divergent economic expectations]( Francesco D’Acunto, Ulrike Malmendier, and Michael Weber Social Sciences [Quantifying collective intelligence in human groups]( Christoph Riedl, Young Ji Kim, Pranav Gupta, Thomas W. Malone, and Anita Williams Woolley [The unintended consequences of US immigration enforcement policies]( Emily Ryo [Carceral-community epidemiology, structural racism, and COVID-19 disparities]( Eric Reinhart and Daniel L. Chen --------------------------------------------------------------- Biological Sciences Anthropology [Plant species richness at archaeological sites suggests ecological legacy of Indigenous subsistence on the Colorado Plateau]( Bruce M. Pavlik, Lisbeth A. Louderback, Kenneth B. Vernon, Peter M. Yaworsky, Cynthia Wilson, Arnold Clifford, and Brian F. Codding Biochemistry [2′-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography]( Mateusz Wilamowski, Darren A. Sherrell, George Minasov, Youngchang Kim, Ludmilla Shuvalova, Alex Lavens, Ryan Chard, Natalia Maltseva, Robert Jedrzejczak, Monica Rosas-Lemus, Nickolaus Saint, Ian T. Foster, Karolina Michalska, Karla J. F. Satchell, and Andrzej Joachimiak [Trapping a cross-linked lysine–tryptophan radical in the catalytic cycle of the radical SAM enzyme SuiB]( Aidin R. Balo, Alessio Caruso, Lizhi Tao, Dean J. Tantillo, Mohammad R. Seyedsayamdost, and R. David Britt [G-quadruplex structural variations in human genome associated with single-nucleotide variations and their impact on gene activity]( Jia-yuan Gong, Cui-jiao Wen, Ming-liang Tang, Rui-fang Duan, Juan-nan Chen, Jia-yu Zhang, Ke-wei Zheng, Yi-de He, Yu-hua Hao, Qun Yu, Su-ping Ren, and Zheng Tan [Pharmacological inhibition of PI5P4Kα/β disrupts cell energy metabolism and selectively kills p53-null tumor cells]( Song Chen, Caroline Chandra Tjin, Xiang Gao, Yi Xue, Haoyan Jiao, Ruilin Zhang, Mengnan Wu, Zunyu He, Jonathan Ellman, and Ya Ha [Structure of Ycf1p reveals the transmembrane domain TMD0 and the regulatory region of ABCC transporters]( Sarah C. Bickers, Samir Benlekbir, John L. Rubinstein, and Voula Kanelis [The SHREAD gene therapy platform for paracrine delivery improves tumor localization and intratumoral effects of a clinical antibody]( Sheena N. Smith, Rajib Schubert, Branko Simic, Dominik Brücher, Markus Schmid, Niels Kirk, Patrick C. Freitag, Viviana Gradinaru, and Andreas Plückthun Biophysics and Computational Biology [Impact of an alpha helix and a cysteine–cysteine disulfide bond on the resistance of bacterial adhesion pili to stress]( Joseph L. Baker, Tobias Dahlberg, Esther Bullitt, and Magnus Andersson [A biophysical limit for quorum sensing in biofilms]( Avaneesh V. Narla, David Bruce Borenstein, and Ned S. Wingreen [Short-lived intermediate in N2O generation by P450 NO reductase captured by time-resolved IR spectroscopy and XFEL crystallography]( Takashi Nomura, Tetsunari Kimura, Yusuke Kanematsu, Daichi Yamada, Keitaro Yamashita, Kunio Hirata, Go Ueno, Hironori Murakami, Tamao Hisano, Raika Yamagiwa, Hanae Takeda, Chai Gopalasingam, Ryota Kousaka, Sachiko Yanagisawa, Osami Shoji, Takashi Kumasaka, Masaki Yamamoto, Yu Takano, Hiroshi Sugimoto, Takehiko Tosha, Minoru Kubo, and Yoshitsugu Shiro [Noncanonical protein kinase A activation by oligomerization of regulatory subunits as revealed by inherited Carney complex mutations]( Naeimeh Jafari, Jason Del Rio, Madoka Akimoto, Jung Ah Byun, Stephen Boulton, Kody Moleschi, Yousif Alsayyed, Pascale Swanson, Jinfeng Huang, Karla Martinez Pomier, Chi Lee, Jian Wu, Susan S. Taylor, and Giuseppe Melacini [On the evolution of chaperones and cochaperones and the expansion of proteomes across the Tree of Life]( Mathieu E. Rebeaud, Saurav Mallik, Pierre Goloubinoff, and Dan S. Tawfik [Encapsulation of ribozymes inside model protocells leads to faster evolutionary adaptation]( Yei-Chen Lai, Ziwei Liu, and Irene A. Chen Cell Biology [Cell lineage tracing links ERα loss in Erbb2-positive breast cancers to the arising of a highly aggressive breast cancer subtype]( Yunfeng Ding, Yonghong Liu, Dong-Kee Lee, Zhangwei Tong, Xiaobin Yu, Yi Li, Yong Xu, Rainer B. Lanz, Bert W. O’Malley, and Jianming Xu [A stress-responsive miRNA regulates BMP signaling to maintain tissue homeostasis]( Sromana Mukherjee, Nuria Paricio, and Nicholas S. Sokol [Structural basis for p50RhoGAP BCH domain–mediated regulation of Rho inactivation]( Vishnu Priyanka Reddy Chichili, Ti Weng Chew, Srihari Shankar, Shi Yin Er, Cheen Fei Chin, Chacko Jobichen, Catherine Qiurong Pan, Yiting Zhou, Foong May Yeong, Boon Chuan Low, and J. Sivaraman Ecology [Global declines in coral reef calcium carbonate production under ocean acidification and warming]( Christopher E. Cornwall, Steeve Comeau, Niklas A. Kornder, Chris T. Perry, Ruben van Hooidonk, Thomas M. DeCarlo, Morgan S. Pratchett, Kristen D. Anderson, Nicola Browne, Robert Carpenter, Guillermo Diaz-Pulido, Juan P. D’Olivo, Steve S. Doo, Joana Figueiredo, Sofia A. V. Fortunato, Emma Kennedy, Coulson A. Lantz, Malcolm T. McCulloch, Manuel González-Rivero, Verena Schoepf, Scott G. Smithers, and Ryan J. Lowe [Dynamic population stage structure due to juvenile–adult asymmetry stabilizes complex ecological communities]( André M. de Roos [Global abundance estimates for 9,700 bird species]( Corey T. Callaghan, Shinichi Nakagawa, and William K. Cornwell [Resistance of African tropical forests to an extreme climate anomaly]( Amy C. Bennett, Greta C. Dargie, Aida Cuni-Sanchez, John Tshibamba Mukendi, Wannes Hubau, Jacques M. Mukinzi, Oliver L. Phillips, Yadvinder Malhi, Martin J. P. Sullivan, Declan L. M. Cooper, Stephen Adu-Bredu, Kofi Affum-Baffoe, Christian A. Amani, Lindsay F. Banin, Hans Beeckman, Serge K. Begne, Yannick E. Bocko, Pascal Boeckx, Jan Bogaert, Terry Brncic, Eric Chezeaux, Connie J. Clark, Armandu K. Daniels, Thales de Haulleville, Marie-Noël Djuikouo Kamdem, Jean-Louis Doucet, Fidèle Evouna Ondo, Corneille E. N. Ewango, Ted R. Feldpausch, Ernest G. Foli, Christelle Gonmadje, Jefferson S. Hall, Olivier J. Hardy, David J. Harris, Suspense A. Ifo, Kathryn J. Jeffery, Elizabeth Kearsley, Miguel Leal, Aurora Levesley, Jean-Remy Makana, Faustin Mbayu Lukasu, Vincent P. Medjibe, Vianet Mihindu, Sam Moore, Natacha Nssi Begone, Georgia C. Pickavance, John R. Poulsen, Jan Reitsma, Bonaventure Sonké, Terry C. H. Sunderland, Hermann Taedoumg, Joey Talbot, Darlington S. Tuagben, Peter M. Umunay, Hans Verbeeck, Jason Vleminckx, Lee J. T. White, Hannsjoerg Woell, John T. Woods, Lise Zemagho, and Simon L. Lewis Environmental Sciences [Coastal eutrophication drives acidification, oxygen loss, and ecosystem change in a major oceanic upwelling system]( Faycal Kessouri, James C. McWilliams, Daniele Bianchi, Martha Sutula, Lionel Renault, Curtis Deutsch, Richard A. Feely, Karen McLaughlin, Minna Ho, Evan M. Howard, Nina Bednaršek, Pierre Damien, Jeroen Molemaker, and Stephen B. Weisberg Evolution [Three genomes in the algal genus Volvox reveal the fate of a haploid sex-determining region after a transition to homothallism]( Kayoko Yamamoto, Takashi Hamaji, Hiroko Kawai-Toyooka, Ryo Matsuzaki, Fumio Takahashi, Yoshiki Nishimura, Masanobu Kawachi, Hideki Noguchi, Yohei Minakuchi, James G. Umen, Atsushi Toyoda, and Hisayoshi Nozaki [Genomic basis of parallel adaptation varies with divergence in Arabidopsis and its relatives]( Magdalena Bohutínská, Jakub Vlček, Sivan Yair, Benjamin Laenen, Veronika Konečná, Marco Fracassetti, Tanja Slotte, and Filip Kolář [Nonparametric coalescent inference of mutation spectrum history and demography]( William S. DeWitt, Kameron Decker Harris, Aaron P. Ragsdale, and Kelley Harris Genetics [Ku70 suppresses alternative end joining in G1-arrested progenitor B cells]( Zhuoyi Liang, Vipul Kumar, Marie Le Bouteiller, Jeffrey Zurita, Josefin Kenrick, Sherry G. Lin, Jiangman Lou, Jianqiao Hu, Adam Yongxin Ye, Cristian Boboila, Frederick W. Alt, and Richard L. Frock Immunology and Inflammation [Galectin-1 fosters an immunosuppressive microenvironment in colorectal cancer by reprogramming CD8+ regulatory T cells]( Alejandro J. Cagnoni, María Laura Giribaldi, Ada G. Blidner, Anabela M. Cutine, Sabrina G. Gatto, Rosa M. Morales, Mariana Salatino, Martín C. Abba, Diego O. Croci, Karina V. Mariño, and Gabriel A. Rabinovich [Nanoparticle-enabled innate immune stimulation activates endogenous tumor-infiltrating T cells with broad antigen specificities]( Qian Yin, Wong Yu, Caitlin L. Grzeskowiak, Jing Li, Huang Huang, Jing Guo, Liang Chen, Feng Wang, Fan Zhao, Lotta von Boehmer, Thomas J. Metzner, John T. Leppert, Yueh-hsiu Chien, Calvin J. Kuo, and Mark M. Davis [DNAM-1 regulates Foxp3 expression in regulatory T cells by interfering with TIGIT under inflammatory conditions]( Kazuki Sato, Yumi Yamashita-Kanemaru, Fumie Abe, Rikito Murata, Yuho Nakamura-Shinya, Kazumasa Kanemaru, Masafumi Muratani, André Veillette, Motohito Goto, Mamoru Ito, Akira Shibuya, and Kazuko Shibuya [Circulating immunity protects the female reproductive tract from Chlamydia infection]( Jasmine C. Labuda, Oanh H. Pham, Claire E. Depew, Kevin D. Fong, Bokyung Lee, Jordan A. Rixon, and Stephen J. McSorley [The immune response is a critical regulator of zebrafish retinal pigment epithelium regeneration]( Lyndsay L. Leach, Nicholas J. Hanovice, Stephanie M. George, Ana E. Gabriel, and Jeffrey M. Gross [LXR directly regulates glycosphingolipid synthesis and affects human CD4+ T cell function]( Kirsty E. Waddington, George A. Robinson, Beatriz Rubio-Cuesta, Eden Chrifi-Alaoui, Sara Andreone, Kok-Siong Poon, Iveta Ivanova, Lucia Martin-Gutierrez, Dylan M. Owen, Elizabeth C. Jury, and Inés Pineda-Torra Medical Sciences [Carceral-community epidemiology, structural racism, and COVID-19 disparities]( Eric Reinhart and Daniel L. Chen [Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of cultured human cells and can be expressed in patient-derived tissues]( Liguo Zhang, Alexsia Richards, M. Inmaculada Barrasa, Stephen H. Hughes, Richard A. Young, and Rudolf Jaenisch [Heparin-binding VEGFR1 variants as long-acting VEGF inhibitors for treatment of intraocular neovascular disorders]( Hong Xin, Nilima Biswas, Pin Li, Cuiling Zhong, Tamara C. Chan, Eric Nudleman, and Napoleone Ferrara [Pharmacological inhibition of MDA-9/Syntenin blocks breast cancer metastasis through suppression of IL-1β]( Anjan K. Pradhan, Santanu Maji, Praveen Bhoopathi, Sarmistha Talukdar, Padmanabhan Mannangatti, Chunqing Guo, Xiang-Yang Wang, Lorraine Colon Cartagena, Michael Idowu, Joseph W. Landry, Devanand Sarkar, Luni Emdad, Webster K. Cavenee, Swadesh K. Das, and Paul B. Fisher [Oncogenic KRAS engages an RSK1/NF1 pathway to inhibit wild-type RAS signaling in pancreatic cancer]( Derek K. Cheng, Tobiloba E. Oni, Jennifer S. Thalappillil, Youngkyu Park, Hsiu-Chi Ting, Brinda Alagesan, Nadia V. Prasad, Kenneth Addison, Keith D. Rivera, Darryl J. Pappin, Linda Van Aelst, and David A. Tuveson Microbiology [Inoculum effect of antimicrobial peptides]( Maria Rosa Loffredo, Filippo Savini, Sara Bobone, Bruno Casciaro, Henrik Franzyk, Maria Luisa Mangoni, and Lorenzo Stella [Gut microbiome contributions to altered metabolism in a pig model of undernutrition]( Hao-Wei Chang, Nathan P. McNulty, Matthew C. Hibberd, David O’Donnell, Jiye Cheng, Vincent Lombard, Bernard Henrissat, Olga Ilkayeva, Michael J. Muehlbauer, Christopher B. Newgard, Michael J. Barratt, Xi Lin, Jack Odle, and Jeffrey I. Gordon [Just 2% of SARS-CoV-2−positive individuals carry 90% of the virus circulating in communities]( Qing Yang, Tassa K. Saldi, Patrick K. Gonzales, Erika Lasda, Carolyn J. Decker, Kimngan L. Tat, Morgan R. Fink, Cole R. Hager, Jack C. Davis, Christopher D. Ozeroff, Denise Muhlrad, Stephen K. Clark, Will T. Fattor, Nicholas R. Meyerson, Camille L. Paige, Alison R. Gilchrist, Arturo Barbachano-Guerrero, Emma R. Worden-Sapper, Sharon S. Wu, Gloria R. Brisson, Matthew B. McQueen, Robin D. Dowell, Leslie Leinwand, Roy Parker, and Sara L. Sawyer [Microevolution in the pansecondary metabolome of Aspergillus flavus and its potential macroevolutionary implications for filamentous fungi]( Milton T. Drott, Tomás A. Rush, Tatum R. Satterlee, Richard J. Giannone, Paul E. Abraham, Claudio Greco, Nandhitha Venkatesh, Jeffrey M. Skerker, N. Louise Glass, Jesse L. Labbé, Michael G. Milgroom, and Nancy P. Keller [HIV envelope tail truncation confers resistance to SERINC5 restriction]( Tafhima Haider, Xenia Snetkov, and Clare Jolly Neuroscience [Chromatin remodeler Arid1a regulates subplate neuron identity and wiring of cortical connectivity]( Daniel Z. Doyle, Mandy M. Lam, Adel Qalieh, Yaman Qalieh, Alice Sorel, Owen H. Funk, and Kenneth Y. Kwan [CXCR4/CXCL12-mediated entrapment of axons at the injury site compromises optic nerve regeneration]( Alexander M. Hilla, Annemarie Baehr, Marco Leibinger, Anastasia Andreadaki, and Dietmar Fischer [Coupling between slow waves and sharp-wave ripples engages distributed neural activity during sleep in humans]( Ivan Skelin, Haoxin Zhang, Jie Zheng, Shiting Ma, Bryce A. Mander, Olivia Kim McManus, Sumeet Vadera, Robert T. Knight, Bruce L. McNaughton, and Jack J. Lin Physiology [Roles of KLF4 and AMPK in the inhibition of glycolysis by pulsatile shear stress in endothelial cells]( Yue Han, Ming He, Traci Marin, Hui Shen, Wei-Ting Wang, Tzong-Yi Lee, Hsiao-Chin Hong, Zong-Lai Jiang, Theodore Garland Jr, John Y.-J. Shyy, Brendan Gongol, and Shu Chien [Reconstitution of β-adrenergic regulation of CaV1.2: Rad-dependent and Rad-independent protein kinase A mechanisms]( Moshe Katz, Suraj Subramaniam, Orna Chomsky-Hecht, Vladimir Tsemakhovich, Veit Flockerzi, Enno Klussmann, Joel A. Hirsch, Sharon Weiss, and Nathan Dascal [Elementary mechanisms of calmodulin regulation of NaV1.5 producing divergent arrhythmogenic phenotypes]( Po Wei Kang, Nourdine Chakouri, Johanna Diaz, Gordon F. Tomaselli, David T. Yue, and Manu Ben-Johny Plant Biology [A synthetic C4 shuttle via the β-hydroxyaspartate cycle in C3 plants]( Marc-Sven Roell, Lennart Schada von Borzyskowski, Philipp Westhoff, Anastasija Plett, Nicole Paczia, Peter Claus, Urte Schlueter, Tobias J. Erb, and Andreas P.M. Weber Psychological and Cognitive Sciences [Odor-driven face-like categorization in the human infant brain]( Diane Rekow, Jean-Yves Baudouin, Fanny Poncet, Fabrice Damon, Karine Durand, Benoist Schaal, Bruno Rossion, and Arnaud Leleu [Cover] --------------------------------------------------------------- This message was sent to {EMAIL}. [Unsubscribe]( from or [edit]( your subscription for this service. Or by mail: Customer Service * 15575-A Los Gatos Blvd * Los Gatos, CA 95032 * U.S.A. 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