PNAS Table of Contents for April 13, 2021; Vol. 118, No. 15 is now complete

[PNAS] [Our Planet, Our Future, Nobel Prize Summit April 26-28, 2021](/cgi/adclick/?ad=55754&adclick=true&url=https%3A%2F%2Fwww.nobelprize.org%2Fevents%2Fnobel-prize-summit%2F2021)   [April 13, 2021; Vol. 118, No. 15]( ) This Week in PNAS [In This Issue]( This week's research highlights --------------------------------------------------------------- News Feature [News Feature: How “forever chemicals” might impair the immune system]( Carolyn Beans An in-depth look at trending science issues --------------------------------------------------------------- QnAs [QnAs with David Bercovici]( Farooq Ahmed Interviews with leading scientific researchers and newsmakers --------------------------------------------------------------- Profile [Profile of Howard Y. Chang]( Farooq Ahmed The life and work of NAS members --------------------------------------------------------------- Commentaries [Prioritizing COVID-19 vaccination by age]( Marcia C. Castro and Burton Singer [The epigenetic regulation of adipose tissue plasticity]( Shingo Kajimura --------------------------------------------------------------- Perspective [Potential ecological impacts of climate intervention by reflecting sunlight to cool Earth]( Phoebe L. Zarnetske, Jessica Gurevitch, Janet Franklin, Peter M. Groffman, Cheryl S. Harrison, Jessica J. Hellmann, Forrest M. Hoffman, Shan Kothari, Alan Robock, Simone Tilmes, Daniele Visioni, Jin Wu, Lili Xia, and Cheng-En Yang --------------------------------------------------------------- Letters [His345 mutant of angiotensin-converting enzyme 2 (ACE2) remains enzymatically active against angiotensin II]( Pan Liu, Xinfang Xie, Li Gao, and Jing Jin [Reply to Liu et al.: Specific mutations matter in specificity and catalysis in ACE2]( Jeff Glasgow, Anum Glasgow, Tanja Kortemme, and James A. Wells [An incorrect wetness-based correction method for deuterium offset]( Ying Zhao [Reply to Zhao: The demonstrated magnitude of artifact during stem water extraction signals a clear need for deuterium correction]( Xin Song, Yongle Chen, Brent R. Helliker, Xianhui Tang, Fang Li, and Youping Zhou --------------------------------------------------------------- Arthur M. Sackler Colloquium on Advancing the Science and Practice of Science Communication: Misinformation about Science in the Public Sphere Introduction [Misinformation about science in the public sphere]( Dietram A. Scheufele, Andrew J. Hoffman, Liz Neeley, and Czerne M. Reid Colloquium Papers [Misinformation and public opinion of science and health: Approaches, findings, and future directions]( Michael A. Cacciatore [Measuring the news and its impact on democracy]( Duncan J. Watts, David M. Rothschild, and Markus Mobius [Misinformation in and about science]( Jevin D. West and Carl T. Bergstrom [Why the backfire effect does not explain the durability of political misperceptions]( Brendan Nyhan [The narrative truth about scientific misinformation]( Michael F. Dahlstrom [A scientific theory of gist communication and misinformation resistance, with implications for health, education, and policy]( Valerie F. Reyna [Emotion and humor as misinformation antidotes]( Sara K. Yeo and Meaghan McKasy [(Mis)informed about what? What it means to be a science-literate citizen in a digital world]( Emily L. Howell and Dominique Brossard --------------------------------------------------------------- Brief Reports [Melanocortin 3 receptor-expressing neurons in the ventromedial hypothalamus promote glucose disposal]( Amy K. Sutton, Paulette B. Goforth, Ian E. Gonzalez, James Dell’Orco, Hongjuan Pei, Martin G. Myers Jr, and David P. Olson [Functional connectome fingerprinting using shallow feedforward neural networks]( Gokce Sarar, Bhaskar Rao, and Thomas Liu --------------------------------------------------------------- Physical Sciences Applied Mathematics [Inference of dynamic systems from noisy and sparse data via manifold-constrained Gaussian processes]( Shihao Yang, Samuel W. K. Wong, and S. C. Kou [Growth, death, and resource competition in sessile organisms]( Edward D. Lee, Christopher P. Kempes, and Geoffrey B. West Applied Physical Sciences [Hyperspectral interference tomography of nacre]( Jad Salman, Cayla A. Stifler, Alireza Shahsafi, Chang-Yu Sun, Stephen C. Weibel, Michel Frising, Bryan E. Rubio-Perez, Yuzhe Xiao, Christopher Draves, Raymond A. Wambold, Zhaoning Yu, Daniel C. Bradley, Gabor Kemeny, Pupa U. P. A. Gilbert, and Mikhail A. Kats [Establishment of heterochromatin in domain-size-dependent bursts]( Jan Fabio Nickels, Ashleigh Katrine Edwards, Sebastian Jespersen Charlton, Amanda Møller Mortensen, Sif Christine Lykke Hougaard, Ala Trusina, Kim Sneppen, and Geneviève Thon Biophysics and Computational Biology [Accurate modeling of DNA conformational flexibility by a multivariate Ising model]( Korbinian Liebl and Martin Zacharias [Mechanosensitive remodeling of the bacterial flagellar motor is independent of direction of rotation]( Navish Wadhwa, Yuhai Tu, and Howard C. Berg [Structural basis for Clostridium perfringens enterotoxin targeting of claudins at tight junctions in mammalian gut]( Alex J. Vecchio, Sewwandi S. Rathnayake, and Robert M. Stroud Chemistry [Direct coordination of pterin to FeII enables neurotransmitter biosynthesis in the pterin-dependent hydroxylases]( Shyam R. Iyer, Kasper D. Tidemand, Jeffrey T. Babicz Jr, Ariel B. Jacobs, Leland B. Gee, Lærke T. Haahr, Yoshitaka Yoda, Masayuki Kurokuzu, Shinji Kitao, Makina Saito, Makoto Seto, Hans E. M. Christensen, Günther H. J. Peters, and Edward I. Solomon [Size dependence of hydrophobic hydration at electrified gold/water interfaces]( Alessandra Serva, Mathieu Salanne, Martina Havenith, and Simone Pezzotti Computer Sciences [Biological structure and function emerge from scaling unsupervised learning to 250 million protein sequences]( Alexander Rives, Joshua Meier, Tom Sercu, Siddharth Goyal, Zeming Lin, Jason Liu, Demi Guo, Myle Ott, C. Lawrence Zitnick, Jerry Ma, and Rob Fergus Earth, Atmospheric, and Planetary Sciences [The contributions of individual countries and regions to the global radiative forcing]( Bo Fu, Bengang Li, Thomas Gasser, Shu Tao, Philippe Ciais, Shilong Piao, Yves Balkanski, Wei Li, Tianya Yin, Luchao Han, Yunman Han, Siyuan Peng, and Jing Xu [Dead clades walking are a pervasive macroevolutionary pattern]( B. Davis Barnes, Judith A. Sclafani, and Andrew Zaffos Engineering [Mechanics of two filaments in tight orthogonal contact]( Paul Grandgeorge, Changyeob Baek, Harmeet Singh, Paul Johanns, Tomohiko G. Sano, Alastair Flynn, John H. Maddocks, and Pedro M. Reis [Human hand as a powerless and multiplexed infrared light source for information decryption and complex signal generation]( Shun An, Wen Shang, Modi Jiang, Yini Luo, Benwei Fu, Chengyi Song, Peng Tao, and Tao Deng [Time–connectivity superposition and the gel/glass duality of weak colloidal gels]( Bavand Keshavarz, Donatien Gomes Rodrigues, Jean-Baptiste Champenois, Matthew G. Frith, Jan Ilavsky, Michela Geri, Thibaut Divoux, Gareth H. McKinley, and Arnaud Poulesquen Mathematics [Fourier uniqueness in even dimensions]( Andrew Bakan, Haakan Hedenmalm, Alfonso Montes-Rodríguez, Danylo Radchenko, and Maryna Viazovska Physics [Topological defects produce kinks in biopolymer filament bundles]( Valentin M. Slepukhin, Maximilian J. Grill, Qingda Hu, Elliot L. Botvinick, Wolfgang A. Wall, and Alex J. Levine Statistics [Confidence intervals for policy evaluation in adaptive experiments]( Vitor Hadad, David A. Hirshberg, Ruohan Zhan, Stefan Wager, and Susan Athey [Density estimation using deep generative neural networks]( Qiao Liu, Jiaze Xu, Rui Jiang, and Wing Hung Wong Sustainability Science [Addressing partial identification in climate modeling and policy analysis]( Charles F. Manski, Alan H. Sanstad, and Stephen J. DeCanio --------------------------------------------------------------- Social Sciences Anthropology [Pre-Columbian transregional captive rearing of Amazonian parrots in the Atacama Desert]( José M. Capriles, Calogero M. Santoro, Richard J. George, Eliana Flores Bedregal, Douglas J. Kennett, Logan Kistler, and Francisco Rothhammer [Combat stress in a small-scale society suggests divergent evolutionary roots for posttraumatic stress disorder symptoms]( Matthew R. Zefferman and Sarah Mathew Economic Sciences [Confidence intervals for policy evaluation in adaptive experiments]( Vitor Hadad, David A. Hirshberg, Ruohan Zhan, Stefan Wager, and Susan Athey [Addressing partial identification in climate modeling and policy analysis]( Charles F. Manski, Alan H. Sanstad, and Stephen J. DeCanio [Earnings growth and the wealth distribution]( Thomas J. Sargent, Neng Wang, and Jinqiang Yang Political Sciences [Why the backfire effect does not explain the durability of political misperceptions]( Brendan Nyhan [Evaluating the effects of shelter-in-place policies during the COVID-19 pandemic]( Christopher R. Berry, Anthony Fowler, Tamara Glazer, Samantha Handel-Meyer, and Alec MacMillen Psychological and Cognitive Sciences [Disentangling perceptual awareness from nonconscious processing in rhesus monkeys (Macaca mulatta)]( Moshe Shay Ben-Haim, Olga Dal Monte, Nicholas A. Fagan, Yarrow Dunham, Ran R. Hassin, Steve W. C. Chang, and Laurie R. Santos [A scientific theory of gist communication and misinformation resistance, with implications for health, education, and policy]( Valerie F. Reyna Social Sciences [Misinformation and public opinion of science and health: Approaches, findings, and future directions]( Michael A. Cacciatore [Measuring the news and its impact on democracy]( Duncan J. Watts, David M. Rothschild, and Markus Mobius [Misinformation in and about science]( Jevin D. West and Carl T. Bergstrom [The narrative truth about scientific misinformation]( Michael F. Dahlstrom [Emotion and humor as misinformation antidotes]( Sara K. Yeo and Meaghan McKasy [(Mis)informed about what? What it means to be a science-literate citizen in a digital world]( Emily L. Howell and Dominique Brossard [Short-term forecasts of expected deaths]( Silvia Rizzi and James W. Vaupel Sustainability Science [Provisional COVID-19 infrastructure induces large, rapid increases in cycling]( Sebastian Kraus and Nicolas Koch --------------------------------------------------------------- Biological Sciences Anthropology [Pre-Columbian transregional captive rearing of Amazonian parrots in the Atacama Desert]( José M. Capriles, Calogero M. Santoro, Richard J. George, Eliana Flores Bedregal, Douglas J. Kennett, Logan Kistler, and Francisco Rothhammer Applied Biological Sciences [Modular complement assemblies for mitigating inflammatory conditions]( Kelly M. Hainline, Lucas S. Shores, Nicole L. Votaw, Zachary J. Bernstein, Sean H. Kelly, Chelsea N. Fries, Marisha S. Madhira, Caslin A. Gilroy, Ashutosh Chilkoti, and Joel H. Collier [Ranking the risk of animal-to-human spillover for newly discovered viruses]( Zoë L. Grange, Tracey Goldstein, Christine K. Johnson, Simon Anthony, Kirsten Gilardi, Peter Daszak, Kevin J. Olival, Tammie O’Rourke, Suzan Murray, Sarah H. Olson, Eri Togami, Gema Vidal, Expert Panel, PREDICT Consortium, and Jonna A. K. Mazet Biochemistry [Direct coordination of pterin to FeII enables neurotransmitter biosynthesis in the pterin-dependent hydroxylases]( Shyam R. Iyer, Kasper D. Tidemand, Jeffrey T. Babicz Jr, Ariel B. Jacobs, Leland B. Gee, Lærke T. Haahr, Yoshitaka Yoda, Masayuki Kurokuzu, Shinji Kitao, Makina Saito, Makoto Seto, Hans E. M. Christensen, Günther H. J. Peters, and Edward I. Solomon [Architecture of the mycobacterial succinate dehydrogenase with a membrane-embedded Rieske FeS cluster]( Xiaoting Zhou, Yan Gao, Weiwei Wang, Xiaolin Yang, Xiuna Yang, Fengjiang Liu, Yanting Tang, Sin Man Lam, Guanghou Shui, Lu Yu, Changlin Tian, Luke W. Guddat, Quan Wang, Zihe Rao, and Hongri Gong Biophysics and Computational Biology [Accurate modeling of DNA conformational flexibility by a multivariate Ising model]( Korbinian Liebl and Martin Zacharias [Topological defects produce kinks in biopolymer filament bundles]( Valentin M. Slepukhin, Maximilian J. Grill, Qingda Hu, Elliot L. Botvinick, Wolfgang A. Wall, and Alex J. Levine [Mechanosensitive remodeling of the bacterial flagellar motor is independent of direction of rotation]( Navish Wadhwa, Yuhai Tu, and Howard C. Berg [Biological structure and function emerge from scaling unsupervised learning to 250 million protein sequences]( Alexander Rives, Joshua Meier, Tom Sercu, Siddharth Goyal, Zeming Lin, Jason Liu, Demi Guo, Myle Ott, C. Lawrence Zitnick, Jerry Ma, and Rob Fergus [Learning the molecular grammar of protein condensates from sequence determinants and embeddings]( Kadi L. Saar, Alexey S. Morgunov, Runzhang Qi, William E. Arter, Georg Krainer, Alpha A. Lee, and Tuomas P. J. Knowles [Cotranscriptional R-loop formation by Mfd involves topological partitioning of DNA]( James R. Portman, Gwendolyn M. Brouwer, Jack Bollins, Nigel J. Savery, and Terence R. Strick Cell Biology [Structural basis for Clostridium perfringens enterotoxin targeting of claudins at tight junctions in mammalian gut]( Alex J. Vecchio, Sewwandi S. Rathnayake, and Robert M. Stroud [Capture and metabolomic analysis of the human endometrial epithelial organoid secretome]( Constantine A. Simintiras, Pramod Dhakal, Chaman Ranjit, Harriet C. Fitzgerald, Ahmed Z. Balboula, and Thomas E. Spencer [Cytokinetic abscission is part of the midblastula transition in early zebrafish embryogenesis]( Shai Adar-Levor, Dikla Nachmias, Shani T. Gal-Oz, Yarden M. Jahn, Nadine Peyrieras, Assaf Zaritsky, Ramon Y. Birnbaum, and Natalie Elia [Myristoylation alone is sufficient for PKA catalytic subunits to associate with the plasma membrane to regulate neuronal functions]( Wei-Hong Xiong, Maozhen Qin, and Haining Zhong [Establishment of bovine expanded potential stem cells]( Lixia Zhao, Xuefei Gao, Yuxuan Zheng, Zixin Wang, Gaoping Zhao, Jie Ren, Jia Zhang, Jian Wu, Baojiang Wu, Yanglin Chen, Wei Sun, Yunxia Li, Jie Su, Yulin Ding, Yuan Gao, Moning Liu, Xiaochun Bai, Liangzhong Sun, Guifang Cao, Fuchou Tang, Siqin Bao, Pentao Liu, and Xihe Li [The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3′-UTRs of yeast mitochondrial mRNAs]( Hauke S. Hillen, Dmitriy A. Markov, Ireneusz D. Wojtas, Katharina B. Hofmann, Michael Lidschreiber, Andrew T. Cowan, Julia L. Jones, Dmitry Temiakov, Patrick Cramer, and Michael Anikin Developmental Biology [Hyperspectral interference tomography of nacre]( Jad Salman, Cayla A. Stifler, Alireza Shahsafi, Chang-Yu Sun, Stephen C. Weibel, Michel Frising, Bryan E. Rubio-Perez, Yuzhe Xiao, Christopher Draves, Raymond A. Wambold, Zhaoning Yu, Daniel C. Bradley, Gabor Kemeny, Pupa U. P. A. Gilbert, and Mikhail A. Kats [Riboflavin instability is a key factor underlying the requirement of a gut microbiota for mosquito development]( Yin Wang, Jai Hoon Eum, Ruby E. Harrison, Luca Valzania, Xiushuai Yang, Jena A. Johnson, Derek T. Huck, Mark R. Brown, and Michael R. Strand [The giant axolotl genome uncovers the evolution, scaling, and transcriptional control of complex gene loci]( Siegfried Schloissnig, Akane Kawaguchi, Sergej Nowoshilow, Francisco Falcon, Leo Otsuki, Pietro Tardivo, Nataliya Timoshevskaya, Melissa C. Keinath, Jeramiah James Smith, S. Randal Voss, and Elly M. Tanaka [BMP heterodimers signal via distinct type I receptor class functions]( Benjamin Tajer, James A. Dutko, Shawn C. Little, and Mary C. Mullins Ecology [Growth, death, and resource competition in sessile organisms]( Edward D. Lee, Christopher P. Kempes, and Geoffrey B. West [Aquatic biodiversity enhances multiple nutritional benefits to humans]( Joey R. Bernhardt and Mary I. O’Connor [Global warming is causing a more pronounced dip in marine species richness around the equator]( Chhaya Chaudhary, Anthony J. Richardson, David S. Schoeman, and Mark J. Costello [Experimental evidence of memory-based foraging decisions in a large wild mammal]( Nathan Ranc, Paul R. Moorcroft, Federico Ossi, and Francesca Cagnacci Environmental Sciences [Declining greenness in Arctic-boreal lakes]( Catherine Kuhn and David Butman Evolution [Dead clades walking are a pervasive macroevolutionary pattern]( B. Davis Barnes, Judith A. Sclafani, and Andrew Zaffos [Primate phageomes are structured by superhost phylogeny and environment]( Jan F. Gogarten, Malte Rühlemann, Elizabeth Archie, Jenny Tung, Chantal Akoua-Koffi, Corinna Bang, Tobias Deschner, Jean-Jacques Muyembe-Tamfun, Martha M. Robbins, Grit Schubert, Martin Surbeck, Roman M. Wittig, Klaus Zuberbühler, John F. Baines, Andre Franke, Fabian H. Leendertz, and Sébastien Calvignac-Spencer [Heritable variation in telomere length predicts mortality in Soay sheep]( Hannah Froy, Sarah L. Underwood, Jennifer Dorrens, Luise A. Seeker, Kathryn Watt, Rachael V. Wilbourn, Jill G. Pilkington, Lea Harrington, Josephine M. Pemberton, and Daniel H. Nussey Genetics [BABEL enables cross-modality translation between multiomic profiles at single-cell resolution]( Kevin E. Wu, Kathryn E. Yost, Howard Y. Chang, and James Zou [Establishment of heterochromatin in domain-size-dependent bursts]( Jan Fabio Nickels, Ashleigh Katrine Edwards, Sebastian Jespersen Charlton, Amanda Møller Mortensen, Sif Christine Lykke Hougaard, Ala Trusina, Kim Sneppen, and Geneviève Thon [Integrated mutational landscape analysis of uterine leiomyosarcomas]( Jungmin Choi, Aranzazu Manzano, Weilai Dong, Stefania Bellone, Elena Bonazzoli, Luca Zammataro, Xiaotong Yao, Aditya Deshpande, Samir Zaidi, Adele Guglielmi, Barbara Gnutti, Nupur Nagarkatti, Joan R. Tymon-Rosario, Justin Harold, Dennis Mauricio, Burak Zeybek, Gulden Menderes, Gary Altwerger, Kyungjo Jeong, Siming Zhao, Natalia Buza, Pei Hui, Antonella Ravaggi, Eliana Bignotti, Chiara Romani, Paola Todeschini, Laura Zanotti, Franco Odicino, Sergio Pecorelli, Laura Ardighieri, Kaya Bilguvar, Charles M. Quick, Dan-Arin Silasi, Gloria S. Huang, Vaagn Andikyan, Mitchell Clark, Elena Ratner, Masoud Azodi, Marcin Imielinski, Peter E. Schwartz, Ludmil B. Alexandrov, Richard P. Lifton, Joseph Schlessinger, and Alessandro D. Santin [Alternative splicing redefines landscape of commonly mutated genes in acute myeloid leukemia]( Osvaldo D. Rivera, Michael J. Mallory, Mathieu Quesnel-Vallières, Rakesh Chatrikhi, David C. Schultz, Martin Carroll, Yoseph Barash, Sara Cherry, and Kristen W. Lynch [A model and test for coordinated polygenic epistasis in complex traits]( Brooke Sheppard, Nadav Rappoport, Po-Ru Loh, Stephan J. Sanders, Noah Zaitlen, and Andy Dahl [Identification of a micropeptide and multiple secondary cell genes that modulate Drosophila male reproductive success]( Clément Immarigeon, Yohan Frei, Sofie Y. N. Delbare, Dragan Gligorov, Pedro Machado Almeida, Jasmine Grey, Léa Fabbro, Emi Nagoshi, Jean-Christophe Billeter, Mariana F. Wolfner, François Karch, and Robert K. Maeda [Inherited deficiency of stress granule ZNFX1 in patients with monocytosis and mycobacterial disease]( Tom Le Voyer, Anna-Lena Neehus, Rui Yang, Masato Ogishi, Jérémie Rosain, Fayhan Alroqi, Maha Alshalan, Sophie Blumental, Fatima Al Ali, Taushif Khan, Manar Ata, Laurence Rozen, Anne Demulder, Paul Bastard, Conor Gruber, Manon Roynard, Yoann Seeleuthener, Franck Rapaport, Benedetta Bigio, Maya Chrabieh, Danielle Sng, Laureline Berteloot, Nathalie Boddaert, Flore Rozenberg, Saleh Al-Muhsen, Aida Bertoli-Avella, Laurent Abel, Dusan Bogunovic, Nico Marr, Davood Mansouri, Fuad Al Mutairi, Vivien Béziat, Dominique Weil, Seyed Alireza Mahdaviani, Alina Ferster, Shen-Ying Zhang, Bruno Reversade, Stéphanie Boisson-Dupuis, Jean-Laurent Casanova, and Jacinta Bustamante Immunology and Inflammation [Epigenetic reprogramming of tumor cell–intrinsic STING function sculpts antigenicity and T cell recognition of melanoma]( Rana Falahat, Anders Berglund, Ryan M. Putney, Patricio Perez-Villarroel, Shota Aoyama, Shari Pilon-Thomas, Glen N. Barber, and James J. Mulé [Immune cells fold and damage fungal hyphae]( Judith M. Bain, M. Fernanda Alonso, Delma S. Childers, Catriona A. Walls, Kevin Mackenzie, Arnab Pradhan, Leanne E. Lewis, Johanna Louw, Gabriela M. Avelar, Daniel E. Larcombe, Mihai G. Netea, Neil A. R. Gow, Gordon D. Brown, Lars P. Erwig, and Alistair J. P. Brown Microbiology [Generation of SARS-CoV-2 reporter replicon for high-throughput antiviral screening and testing]( Xi He, Shuo Quan, Min Xu, Silveria Rodriguez, Shih Lin Goh, Jiajie Wei, Arthur Fridman, Kenneth A. Koeplinger, Steve S. Carroll, Jay A. Grobler, Amy S. Espeseth, David B. Olsen, Daria J. Hazuda, and Dai Wang [Virus-induced cell gigantism and asymmetric cell division in archaea]( Junfeng Liu, Virginija Cvirkaite-Krupovic, Diana P. Baquero, Yunfeng Yang, Qi Zhang, Yulong Shen, and Mart Krupovic [Cardiolipin aids in lipopolysaccharide transport to the gram-negative outer membrane]( Martin V. Douglass, François Cléon, and M. Stephen Trent [Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins]( Wen Cui, Elisabeth Braun, Wei Wang, Jinhong Tang, Yanyan Zheng, Benjamin Slater, Na Li, Cheng Chen, Qingxiang Liu, Bin Wang, Xiu Li, Yinkai Duan, Yunjie Xiao, Ruijiao Ti, Dominik Hotter, Xiaoyun Ji, Lei Zhang, Jun Cui, Yong Xiong, Daniel Sauter, Zefang Wang, Frank Kirchhoff, and Haitao Yang Neuroscience [Overexpression of CD47 is associated with brain overgrowth and 16p11.2 deletion syndrome]( Jingling Li, Thomas Brickler, Allison Banuelos, Kristopher Marjon, Anna Shcherbina, Sravani Banerjee, Jing Bian, Cyndhavi Narayanan, Irving L. Weissman, and Sundari Chetty [4E-BP2–dependent translation in parvalbumin neurons controls epileptic seizure threshold]( Vijendra Sharma, Rapita Sood, Danning Lou, Tzu-Yu Hung, Maxime Lévesque, Yelin Han, Jeremy Y. Levett, Peng Wang, Shravan Murthy, Shannon Tansley, Siyan Wang, Nadeem Siddiqui, Soroush Tahmasebi, Kobi Rosenblum, Massimo Avoli, Jean-Claude Lacaille, Nahum Sonenberg, and Arkady Khoutorsky [Soluble α-synuclein–antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia]( Dorit Trudler, Kristopher L. Nazor, Yvonne S. Eisele, Titas Grabauskas, Nima Dolatabadi, James Parker, Abdullah Sultan, Zhenyu Zhong, Marshall S. Goodwin, Yona Levites, Todd E. Golde, Jeffery W. Kelly, Michael R. Sierks, Nicholas J. Schork, Michael Karin, Rajesh Ambasudhan, and Stuart A. Lipton [Cholinergic suppression of hippocampal sharp-wave ripples impairs working memory]( Yiyao Zhang, Liang Cao, Viktor Varga, Miao Jing, Mursel Karadas, Yulong Li, and György Buzsáki [MrgprC11+ sensory neurons mediate glabrous skin itch]( Haley R. Steele, Yanyan Xing, Yuyan Zhu, Henry B. Hilley, Katy Lawson, Yeseul Nho, Taylor Niehoff, and Liang Han [Integrins protect sensory neurons in models of paclitaxel-induced peripheral sensory neuropathy]( Grace Ji-eun Shin, Maria Elena Pero, Luke A. Hammond, Anita Burgos, Atul Kumar, Samantha E. Galindo, Tanguy Lucas, Francesca Bartolini, and Wesley B. Grueber [Impact of prenatal maternal cytokine exposure on sex differences in brain circuitry regulating stress in offspring 45 years later]( Jill M. Goldstein, Justine E. Cohen, Klara Mareckova, Laura Holsen, Susan Whitfield-Gabrieli, Stephen E. Gilman, Stephen L. Buka, and Mady Hornig [A neural circuit for competing approach and defense underlying prey capture]( Daniel Rossier, Violetta La Franca, Taddeo Salemi, Silvia Natale, and Cornelius T. Gross Plant Biology [Conditional destabilization of the TPLATE complex impairs endocytic internalization]( Jie Wang, Klaas Yperman, Peter Grones, Qihang Jiang, Jonathan Dragwidge, Evelien Mylle, Eliana Mor, Jonah Nolf, Dominique Eeckhout, Geert De Jaeger, Bert De Rybel, Roman Pleskot, and Daniel Van Damme [Multiple independent recombinations led to hermaphroditism in grapevine]( Cheng Zou, Mélanie Massonnet, Andrea Minio, Sagar Patel, Victor Llaca, Avinash Karn, Fred Gouker, Lance Cadle-Davidson, Bruce Reisch, Anne Fennell, Dario Cantu, Qi Sun, and Jason P. Londo Population Biology [Genomic stability through time despite decades of exploitation in cod on both sides of the Atlantic]( Malin L. Pinsky, Anne Maria Eikeset, Cecilia Helmerson, Ian R. Bradbury, Paul Bentzen, Corey Morris, Agata T. Gondek-Wyrozemska, Helle Tessand Baalsrud, Marine Servane Ono Brieuc, Olav Sigurd Kjesbu, Jane A. Godiksen, Julia M. I. Barth, Michael Matschiner, Nils Chr. Stenseth, Kjetill S. Jakobsen, Sissel Jentoft, and Bastiaan Star Sustainability Science [Aquatic biodiversity enhances multiple nutritional benefits to humans]( Joey R. Bernhardt and Mary I. O’Connor --------------------------------------------------------------- Editorial Expressions of Concern [Editorial Expression of Concern: The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis]( [Editorial Expression of Concern: Visualizing active viral infection reveals diverse cell fates in synchronized algal bloom demise]( [Cover] --------------------------------------------------------------- This message was sent to {EMAIL}. [Unsubscribe]( from or [edit]( your subscription for this service. 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