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PNAS Table of Contents for February 23, 2021; Vol. 118, No. 8 is now complete

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  This Week in PNAS This week's research highlights -----------------------------------------------

[PNAS] [PNAS-Highlights-eTOC](/cgi/adclick/?ad=55615&adclick=true&url=https%3A%2F%2Fpnas.us15.list-manage.com%2Fsubscribe%2Fpost%3Fu%3D371d96023d24fb109b778621f%26id%3Db053c2ccce%26SIGNUP%3Dfmportal)   [February 23, 2021; Vol. 118, No. 8]( ) This Week in PNAS [In This Issue]( This week's research highlights --------------------------------------------------------------- Inner Workings [Inner Workings: Advances in infectious disease treatment promise to expand the pool of donor organs]( Jyoti Madhusoodanan An over-the-shoulder look at scientists at work --------------------------------------------------------------- Retrospective [Harold A. Scheraga (10/18/1921–8/1/2020): A pioneering scientist who laid the foundations of protein science in the 20th century]( Hagai Meirovitch and Ivet Bahar --------------------------------------------------------------- Profile [Profile of Mark Stoneking]( Jennifer Viegas The life and work of NAS members --------------------------------------------------------------- Commentaries [Speaking my truth: Why personal experiences can bridge divides but mislead]( Jay J. Van Bavel, Diego A. Reinero, Victoria Spring, Elizabeth A. Harris, and Annie Duke [Invasive mussels regulate nutrient cycling in the largest freshwater ecosystem on Earth]( Michael J. Vanni --------------------------------------------------------------- Perspective [Darwin, sexual selection, and the brain]( Michael J. Ryan --------------------------------------------------------------- Letters [Depressed mood, a better predictor of social-distancing compliance and candidate for intervention compared to working memory capacity]( Medhi Marot, Johann Chevalère, and Nicolas Spatola [Reply to Marot et al.: The struggle to comply with social-distancing is multifaceted, as are the ways of mitigating it]( Weizhen Xie and Weiwei Zhang [Dipyridamole, chloroquine, montelukast sodium, candesartan, oxytetracycline, and atazanavir are not SARS-CoV-2 main protease inhibitors]( Chunlong Ma and Jun Wang [Reply to Ma and Wang: Reliability of various in vitro activity assays on SARS-CoV-2 main protease inhibitors]( Zhe Li, Yuxi Lin, Yi-You Huang, Runduo Liu, Chang-Guo Zhan, Xin Wang, and Hai-Bin Luo --------------------------------------------------------------- Brief Report [Mambalgin-3 potentiates human acid-sensing ion channel 1b under mild to moderate acidosis: Implications as an analgesic lead]( Ben Cristofori-Armstrong, Elena Budusan, and Lachlan D. Rash --------------------------------------------------------------- Physical Sciences Applied Physical Sciences [Nonlinear convergence boosts information coding in circuits with parallel outputs]( Gabrielle J. Gutierrez, Fred Rieke, and Eric T. Shea-Brown [Dissipation bounds the amplification of transition rates far from equilibrium]( Benjamin Kuznets-Speck and David T. Limmer Astronomy [A backward-spinning star with two coplanar planets]( Maria Hjorth, Simon Albrecht, Teruyuki Hirano, Joshua N. Winn, Rebekah I. Dawson, J. J. Zanazzi, Emil Knudstrup, and Bun’ei Sato Biophysics and Computational Biology [Structured sequences emerge from random pool when replicated by templated ligation]( Patrick W. Kudella, Alexei V. Tkachenko, Annalena Salditt, Sergei Maslov, and Dieter Braun [Emergence of diauxie as an optimal growth strategy under resource allocation constraints in cellular metabolism]( Pierre Salvy and Vassily Hatzimanikatis [Differential biosynthesis and cellular permeability explain longitudinal gibberellin gradients in growing roots]( Annalisa Rizza, Bijun Tang, Claire E. Stanley, Guido Grossmann, Markus R. Owen, Leah R. Band, and Alexander M. Jones [Competitive binding of independent extension and retraction motors explains the quantitative dynamics of type IV pili]( Matthias D. Koch, Chenyi Fei, Ned S. Wingreen, Joshua W. Shaevitz, and Zemer Gitai [Tissue folding at the organ–meristem boundary results in nuclear compression and chromatin compaction]( Kateryna Fal, Niklas Korsbo, Juan Alonso-Serra, Jose Teles, Mengying Liu, Yassin Refahi, Marie-Edith Chabouté, Henrik Jönsson, and Olivier Hamant [Mechanism and function of root circumnutation]( Isaiah Taylor, Kevin Lehner, Erin McCaskey, Niba Nirmal, Yasemin Ozkan-Aydin, Mason Murray-Cooper, Rashmi Jain, Elliot W. Hawkes, Pamela C. Ronald, Daniel I. Goldman, and Philip N. Benfey Chemistry [Selenomethionine as an expressible handle for bioconjugations]( Dillon T. Flood, Jordi C. J. Hintzen, Kyle W. Knouse, David E. Hill, Chenxi Lu, Philip A. Cistrone, Jason S. Chen, Takanori Otomo, and Philip. E. Dawson [A de novo strategy to develop NIR precipitating fluorochrome for long-term in situ cell membrane bioimaging]( Ke Li, Yifan Lyu, Yan Huang, Shuai Xu, Hong-Wen Liu, Lanlan Chen, Tian-Bing Ren, Mengyi Xiong, Shuangyan Huan, Lin Yuan, Xiao-Bing Zhang, and Weihong Tan [Ferromagnetic liquid droplets with adjustable magnetic properties]( Xuefei Wu, Robert Streubel, Xubo Liu, Paul Y. Kim, Yu Chai, Qin Hu, Dong Wang, Peter Fischer, and Thomas P. Russell [Kinetic description of site ensembles on catalytic surfaces]( Neil K. Razdan and Aditya Bhan Earth, Atmospheric, and Planetary Sciences [Heterogeneous Hadean crust with ambient mantle affinity recorded in detrital zircons of the Green Sandstone Bed, South Africa]( Nadja Drabon, Benjamin L. Byerly, Gary R. Byerly, Joseph L. Wooden, C. Brenhin Keller, and Donald R. Lowe [Climate control on terrestrial biospheric carbon turnover]( Timothy I. Eglinton, Valier V. Galy, Jordon D. Hemingway, Xiaojuan Feng, Hongyan Bao, Thomas M. Blattmann, Angela F. Dickens, Hannah Gies, Liviu Giosan, Negar Haghipour, Pengfei Hou, Maarten Lupker, Cameron P. McIntyre, Daniel B. Montluçon, Bernhard Peucker-Ehrenbrink, Camilo Ponton, Enno Schefuß, Melissa S. Schwab, Britta M. Voss, Lukas Wacker, Ying Wu, and Meixun Zhao [Precise initial abundance of Niobium-92 in the Solar System and implications for p-process nucleosynthesis]( Makiko K. Haba, Yi-Jen Lai, Jörn-Frederik Wotzlaw, Akira Yamaguchi, Maria Lugaro, and Maria Schönbächler [Northward dispersal of dinosaurs from Gondwana to Greenland at the mid-Norian (215–212 Ma, Late Triassic) dip in atmospheric pCO2]( Dennis V. Kent and Lars B. Clemmensen [Aqueous production of secondary organic aerosol from fossil-fuel emissions in winter Beijing haze]( Junfeng Wang, Jianhuai Ye, Qi Zhang, Jian Zhao, Yangzhou Wu, Jingyi Li, Dantong Liu, Weijun Li, Yange Zhang, Cheng Wu, Conghui Xie, Yiming Qin, Yali Lei, Xiangpeng Huang, Jianping Guo, Pengfei Liu, Pingqing Fu, Yongjie Li, Hyun Chul Lee, Hyoungwoo Choi, Jie Zhang, Hong Liao, Mindong Chen, Yele Sun, Xinlei Ge, Scot T. Martin, and Daniel J. Jacob [Trivalent chromium isotopes in the eastern tropical North Pacific oxygen-deficient zone]( Tianyi Huang, Simone B. Moos, and Edward A. Boyle Engineering [Elastic-instability–enabled locomotion]( Amit Nagarkar, Won-Kyu Lee, Daniel J. Preston, Markus P. Nemitz, Nan-Nan Deng, George M. Whitesides, and L. Mahadevan [Fundamental insight into electrochemical oxidation of methane towards methanol on transition metal oxides]( Aditya Prajapati, Brianna A. Collins, Jason D. Goodpaster, and Meenesh R. Singh [Exhaled aerosol increases with COVID-19 infection, age, and obesity]( David A. Edwards, Dennis Ausiello, Jonathan Salzman, Tom Devlin, Robert Langer, Brandon J. Beddingfield, Alyssa C. Fears, Lara A. Doyle-Meyers, Rachel K. Redmann, Stephanie Z. Killeen, Nicholas J. Maness, and Chad J. Roy Environmental Sciences [The extent of soil loss across the US Corn Belt]( Evan A. Thaler, Isaac J. Larsen, and Qian Yu [Mechanistic transmission modeling of COVID-19 on the Diamond Princess cruise ship demonstrates the importance of aerosol transmission]( Parham Azimi, Zahra Keshavarz, Jose Guillermo Cedeno Laurent, Brent Stephens, and Joseph G. Allen Mathematics [A surprising formula for Sobolev norms]( Haïm Brezis, Jean Van Schaftingen, and Po-Lam Yung Physics [Giant spontaneous Hall effect in a nonmagnetic Weyl–Kondo semimetal]( Sami Dzsaber, Xinlin Yan, Mathieu Taupin, Gaku Eguchi, Andrey Prokofiev, Toni Shiroka, Peter Blaha, Oleg Rubel, Sarah E. Grefe, Hsin-Hua Lai, Qimiao Si, and Silke Paschen [Nonreciprocity of spin waves in the conical helix state]( N. Ogawa, L. Köhler, M. Garst, S. Toyoda, S. Seki, and Y. Tokura Statistics [Stable reliability diagrams for probabilistic classifiers]( Timo Dimitriadis, Tilmann Gneiting, and Alexander I. Jordan --------------------------------------------------------------- Social Sciences Anthropology [Ancient DNA and multimethod dating confirm the late arrival of anatomically modern humans in southern China]( Xue-feng Sun, Shao-qing Wen, Cheng-qiu Lu, Bo-yan Zhou, Darren Curnoe, Hua-yu Lu, Hong-chun Li, Wei Wang, Hai Cheng, Shuang-wen Yi, Xin Jia, Pan-xin Du, Xing-hua Xu, Yi-ming Lu, Ying Lu, Hong-xiang Zheng, Hong Zhang, Chang Sun, Lan-hai Wei, Fei Han, Juan Huang, R. Lawrence Edwards, Li Jin, and Hui Li Economic Sciences [Effects of short birth spacing on birth-order differences in child stunting: Evidence from India]( Sunaina Dhingra and Prabhu L. Pingali Environmental Sciences [Human casualties are the dominant cost of human–wildlife conflict in India]( Sumeet Gulati, Krithi K. Karanth, Nguyet Anh Le, and Frederik Noack Psychological and Cognitive Sciences [Optimizing the selection of fillers in police lineups]( Melissa F. Colloff, Brent M. Wilson, Travis M. Seale-Carlisle, and John T. Wixted [Changing personality traits with the help of a digital personality change intervention]( Mirjam Stieger, Christoph Flückiger, Dominik Rüegger, Tobias Kowatsch, Brent W. Roberts, and Mathias Allemand [Social distancing decreases an individual’s likelihood of contracting COVID-19]( Russell H. Fazio, Benjamin C. Ruisch, Courtney A. Moore, Javier A. Granados Samayoa, Shelby T. Boggs, and Jesse T. Ladanyi [Pathogen disgust sensitivity protects against infection in a high pathogen environment]( Tara J. Cepon-Robins, Aaron D. Blackwell, Theresa E. Gildner, Melissa A. Liebert, Samuel S. Urlacher, Felicia C. Madimenos, Geeta N. Eick, J. Josh Snodgrass, and Lawrence S. Sugiyama Social Sciences [Pandemic precarity: COVID-19 is exposing and exacerbating inequalities in the American heartland]( Brea L. Perry, Brian Aronson, and Bernice A. Pescosolido --------------------------------------------------------------- Biological Sciences Agricultural Sciences [A critical role of the soybean evening complex in the control of photoperiod sensitivity and adaptation]( Tiantian Bu, Sijia Lu, Kai Wang, Lidong Dong, Shilin Li, Qiguang Xie, Xiaodong Xu, Qun Cheng, Liyu Chen, Chao Fang, Haiyang Li, Baohui Liu, James L. Weller, and Fanjiang Kong Anthropology [Pathogen disgust sensitivity protects against infection in a high pathogen environment]( Tara J. Cepon-Robins, Aaron D. Blackwell, Theresa E. Gildner, Melissa A. Liebert, Samuel S. Urlacher, Felicia C. Madimenos, Geeta N. Eick, J. Josh Snodgrass, and Lawrence S. Sugiyama Applied Biological Sciences [Inhibitors of cullin-RING E3 ubiquitin ligase 4 with antitumor potential]( Kenneth Wu, Khoi Q. Huynh, Iris Lu, Moses Moustakim, Haibin Miao, Clinton Yu, Matthew J. Haeusgen, Benjamin D. Hopkins, Lan Huang, Ning Zheng, Roberto Sanchez, Robert J. DeVita, and Zhen-Qiang Pan [Early systemic immune biomarkers predict bone regeneration after trauma]( Albert Cheng, Casey E. Vantucci, Laxminarayanan Krishnan, Marissa A. Ruehle, Theresa Kotanchek, Levi B. Wood, Krishnendu Roy, and Robert E. Guldberg Biochemistry [Selenomethionine as an expressible handle for bioconjugations]( Dillon T. Flood, Jordi C. J. Hintzen, Kyle W. Knouse, David E. Hill, Chenxi Lu, Philip A. Cistrone, Jason S. Chen, Takanori Otomo, and Philip. E. Dawson [A de novo strategy to develop NIR precipitating fluorochrome for long-term in situ cell membrane bioimaging]( Ke Li, Yifan Lyu, Yan Huang, Shuai Xu, Hong-Wen Liu, Lanlan Chen, Tian-Bing Ren, Mengyi Xiong, Shuangyan Huan, Lin Yuan, Xiao-Bing Zhang, and Weihong Tan [Mapping proteolytic neo-N termini at the surface of living cells]( Amy M. Weeks, James R. Byrnes, Irene Lui, and James A. Wells [Interface mobility between monomers in dimeric bovine ATP synthase participates in the ultrastructure of inner mitochondrial membranes]( Tobias E. Spikes, Martin G. Montgomery, and John E. Walker [Transiently structured head domains control intermediate filament assembly]( Xiaoming Zhou, Yi Lin, Masato Kato, Eiichiro Mori, Glen Liszczak, Lillian Sutherland, Vasiliy O. Sysoev, Dylan T. Murray, Robert Tycko, and Steven L. McKnight [Double inhibition and activation mechanisms of Ephexin family RhoGEFs]( Meng Zhang, Lin Lin, Chao Wang, and Jinwei Zhu Biophysics and Computational Biology [Dissipation bounds the amplification of transition rates far from equilibrium]( Benjamin Kuznets-Speck and David T. Limmer [Nonselective cation permeation in an AMPA-type glutamate receptor]( Johann Biedermann, Sebastian Braunbeck, Andrew J. R. Plested, and Han Sun [Displacement of the Na+/K+ pump’s transmembrane domains demonstrates conserved conformational changes in P-type 2 ATPases]( Victoria C. Young and Pablo Artigas [Molecular mechanisms of assembly and TRIP13-mediated remodeling of the human Shieldin complex]( Wei Xie, Shengliu Wang, Juncheng Wang, M. Jason de la Cruz, Guotai Xu, Maurizio Scaltriti, and Dinshaw J. Patel Cell Biology [A specific basal body linker protein provides the connection function for basal body inheritance in trypanosomes]( De-Hua Lai, Flavia Moreira-Leite, Zhi-Shen Xu, Jiong Yang, and Keith Gull [Receptor-like role for PQLC2 amino acid transporter in the lysosomal sensing of cationic amino acids]( Gabriel Talaia, Joseph Amick, and Shawn M. Ferguson [Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate]( Tyler M. Lu, Sean Houghton, Tarig Magdeldin, José Gabriel Barcia Durán, Andrew P. Minotti, Amanda Snead, Andrew Sproul, Duc-Huy T. Nguyen, Jenny Xiang, Howard A. Fine, Zev Rosenwaks, Lorenz Studer, Shahin Rafii, Dritan Agalliu, David Redmond, and Raphaël Lis [SOX9 keeps growth plates and articular cartilage healthy by inhibiting chondrocyte dedifferentiation/osteoblastic redifferentiation]( Abdul Haseeb, Ranjan Kc, Marco Angelozzi, Charles de Charleroy, Danielle Rux, Robert J. Tower, Lutian Yao, Renata Pellegrino da Silva, Maurizio Pacifici, Ling Qin, and Véronique Lefebvre Developmental Biology [Differential biosynthesis and cellular permeability explain longitudinal gibberellin gradients in growing roots]( Annalisa Rizza, Bijun Tang, Claire E. Stanley, Guido Grossmann, Markus R. Owen, Leah R. Band, and Alexander M. Jones [Identification of a nuclear receptor/coactivator developmental signaling pathway in the nematode parasite Strongyloides stercoralis]( Mi Cheong Cheong, Zhu Wang, Tegegn G. Jaleta, Xinshe Li, James B. Lok, Steven A. Kliewer, and David J. Mangelsdorf [The ecdysone-induced protein 93 is a key factor regulating gonadotrophic cycles in the adult female mosquito Aedes aegypti]( Xueli Wang, Yike Ding, Xiangyang Lu, Danqian Geng, Shan Li, Alexander S. Raikhel, and Zhen Zou [The male germline-specific protein MAPS is indispensable for pachynema progression and fertility]( Miao Li, Jiahuan Zheng, Gaopeng Li, Zexiong Lin, Dongliang Li, Dongteng Liu, Haiwei Feng, Dandan Cao, Ernest H. Y. Ng, Raymond H. W. Li, Chunsheng Han, William S. B. Yeung, Louise T. Chow, Hengbin Wang, and Kui Liu Environmental Sciences [Human casualties are the dominant cost of human–wildlife conflict in India]( Sumeet Gulati, Krithi K. Karanth, Nguyet Anh Le, and Frederik Noack Evolution [Structured sequences emerge from random pool when replicated by templated ligation]( Patrick W. Kudella, Alexei V. Tkachenko, Annalena Salditt, Sergei Maslov, and Dieter Braun [Sexually antagonistic coevolution between the sex chromosomes of Drosophila melanogaster]( Katrine K. Lund-Hansen, Colin Olito, Edward H. Morrow, and Jessica K. Abbott [The evolution of siphonophore tentilla for specialized prey capture in the open ocean]( Alejandro Damian-Serrano, Steven H. D. Haddock, and Casey W. Dunn Genetics [Ancient DNA and multimethod dating confirm the late arrival of anatomically modern humans in southern China]( Xue-feng Sun, Shao-qing Wen, Cheng-qiu Lu, Bo-yan Zhou, Darren Curnoe, Hua-yu Lu, Hong-chun Li, Wei Wang, Hai Cheng, Shuang-wen Yi, Xin Jia, Pan-xin Du, Xing-hua Xu, Yi-ming Lu, Ying Lu, Hong-xiang Zheng, Hong Zhang, Chang Sun, Lan-hai Wei, Fei Han, Juan Huang, R. Lawrence Edwards, Li Jin, and Hui Li [Trichoderma reesei Rad51 tolerates mismatches in hybrid meiosis with diverse genome sequences]( Wan-Chen Li, Chia-Yi Lee, Wei-Hsuan Lan, Tai-Ting Woo, Hou-Cheng Liu, Hsin-Yi Yeh, Hao-Yen Chang, Yu-Chien Chuang, Chiung-Ya Chen, Chi-Ning Chuang, Chia-Ling Chen, Yi-Ping Hsueh, Hung-Wen Li, Peter Chi, and Ting-Fang Wang [Cell type-specific modulation of healthspan by Forkhead family transcription factors in the nervous system]( Ekin Bolukbasi, Nathaniel S. Woodling, Dobril K. Ivanov, Jennifer Adcott, Andrea Foley, Arjunan Rajasingam, Lauren M. Gittings, Benjamin Aleyakpo, Teresa Niccoli, Janet M. Thornton, and Linda Partridge [Accurate SNV detection in single cells by transposon-based whole-genome amplification of complementary strands]( Dong Xing, Longzhi Tan, Chi-Han Chang, Heng Li, and X. Sunney Xie [RPA-mediated recruitment of Bre1 couples histone H2B ubiquitination to DNA replication and repair]( Guangxue Liu, Jiaqi Yan, Xuejie Wang, Junliang Chen, Xin Wang, Yang Dong, Simin Zhang, Xiaoli Gan, Jun Huang, and Xuefeng Chen [The Srs2 helicase dampens DNA damage checkpoint by recycling RPA from chromatin]( Nalini Dhingra, Sahiti Kuppa, Lei Wei, Nilisha Pokhrel, Silva Baburyan, Xiangzhou Meng, Edwin Antony, and Xiaolan Zhao Immunology and Inflammation [Astrocytes lure CXCR2-expressing CD4+ T cells to gray matter via TAK1-mediated chemokine production in a mouse model of multiple sclerosis]( Yee Ming Khaw, Abbey Tierney, Claire Cunningham, Katiria Soto-Díaz, Eunjoo Kang, Andrew J. Steelman, and Makoto Inoue [Activation of NF-κB and p300/CBP potentiates cancer chemoimmunotherapy through induction of MHC-I antigen presentation]( Yixuan Zhou, Ingmar Niels Bastian, Mark D. Long, Michelle Dow, Weihua Li, Tao Liu, Rachael Katie Ngu, Laura Antonucci, Jian Yu Huang, Qui T. Phung, Xi-he Zhao, Sourav Banerjee, Xue-Jia Lin, Hongxia Wang, Brian Dang, Sylvia Choi, Daniel Karin, Hua Su, Mark H. Ellisman, Christina Jamieson, Marcus Bosenberg, Zhang Cheng, Johannes Haybaeck, Lukas Kenner, Kathleen M. Fisch, Richard Bourgon, Genevive Hernandez, Jennie R. Lill, Song Liu, Hannah Carter, Ira Mellman, Michael Karin, and Shabnam Shalapour Medical Sciences [Exhaled aerosol increases with COVID-19 infection, age, and obesity]( David A. Edwards, Dennis Ausiello, Jonathan Salzman, Tom Devlin, Robert Langer, Brandon J. Beddingfield, Alyssa C. Fears, Lara A. Doyle-Meyers, Rachel K. Redmann, Stephanie Z. Killeen, Nicholas J. Maness, and Chad J. Roy [NAD+ depletion by type I interferon signaling sensitizes pancreatic cancer cells to NAMPT inhibition]( Alexandra M. Moore, Lei Zhou, Jing Cui, Luyi Li, Nanping Wu, Alice Yu, Soumya Poddar, Keke Liang, Evan R. Abt, Stephanie Kim, Razmik Ghukasyan, Nooneh Khachatourian, Kristina Pagano, Irmina Elliott, Amanda M. Dann, Rana Riahi, Thuc Le, David W. Dawson, Caius G. Radu, and Timothy R. Donahue [Modeling SARS-CoV-2 viral kinetics and association with mortality in hospitalized patients from the French COVID cohort]( Nadège Néant, Guillaume Lingas, Quentin Le Hingrat, Jade Ghosn, Ilka Engelmann, Quentin Lepiller, Alexandre Gaymard, Virginie Ferré, Cédric Hartard, Jean-Christophe Plantier, Vincent Thibault, Julien Marlet, Brigitte Montes, Kevin Bouiller, François-Xavier Lescure, Jean-François Timsit, Emmanuel Faure, Julien Poissy, Christian Chidiac, François Raffi, Antoine Kimmoun, Manuel Etienne, Jean-Christophe Richard, Pierre Tattevin, Denis Garot, Vincent Le Moing, Delphine Bachelet, Coralie Tardivon, Xavier Duval, Yazdan Yazdanpanah, France Mentré, Cédric Laouénan, Benoit Visseaux, Jérémie Guedj, and for the French COVID Cohort Investigators and French Cohort Study groups [ZMYND8 preferentially binds phosphorylated EZH2 to promote a PRC2-dependent to -independent function switch in hypoxia-inducible factor–activated cancer]( Bo Tang, Rui Sun, Dejie Wang, Haoyue Sheng, Ting Wei, Liguo Wang, Jun Zhang, Thai H. Ho, Lu Yang, Qiang Wei, and Haojie Huang Microbiology [Competitive binding of independent extension and retraction motors explains the quantitative dynamics of type IV pili]( Matthias D. Koch, Chenyi Fei, Ned S. Wingreen, Joshua W. Shaevitz, and Zemer Gitai [The DUF1013 protein TrcR tracks with RNA polymerase to control the bacterial cell cycle and protect against antibiotics]( Marie Delaby, Lydia M. Varesio, Laurence Degeorges, Sean Crosson, and Patrick H. Viollier [Dual-purpose isocyanides produced by Aspergillus fumigatus contribute to cellular copper sufficiency and exhibit antimicrobial activity]( Nicholas Raffa, Tae Hyung Won, Andrew Sukowaty, Kathleen Candor, Chengsen Cui, Saayak Halder, Mingji Dai, Julio A. Landero-Figueroa, Frank C. Schroeder, and Nancy P. Keller [Influenza hemagglutinin-specific IgA Fc-effector functionality is restricted to stalk epitopes]( Alec W. Freyn, Julianna Han, Jenna J. Guthmiller, Mark J. Bailey, Karlynn Neu, Hannah L. Turner, Victoria C. Rosado, Veronika Chromikova, Min Huang, Shirin Strohmeier, Sean T. H. Liu, Viviana Simon, Florian Krammer, Andrew B. Ward, Peter Palese, Patrick C. Wilson, and Raffael Nachbagauer Neuroscience [Nonlinear convergence boosts information coding in circuits with parallel outputs]( Gabrielle J. Gutierrez, Fred Rieke, and Eric T. Shea-Brown [Cognitive aging is associated with redistribution of synaptic weights in the hippocampus]( Eric W. Buss, Nicola J. Corbett, Joshua G. Roberts, Natividad Ybarra, Timothy F. Musial, Dina Simkin, Elizabeth Molina-Campos, Kwang-Jin Oh, Lauren L. Nielsen, Gelique D. Ayala, Sheila A. Mullen, Anise K. Farooqi, Gary X. D’Souza, Corinne L. Hill, Linda A. Bean, Annalise E. Rogalsky, Matthew L. Russo, Dani M. Curlik, Marci D. Antion, Craig Weiss, Dane M. Chetkovich, M. Matthew Oh, John F. Disterhoft, and Daniel A. Nicholson [An ecologically motivated image dataset for deep learning yields better models of human vision]( Johannes Mehrer, Courtney J. Spoerer, Emer C. Jones, Nikolaus Kriegeskorte, and Tim C. Kietzmann [Nile Red fluorescence spectroscopy reports early physicochemical changes in myelin with high sensitivity]( Wulin Teo, Andrew V. Caprariello, Megan L. Morgan, Antonio Luchicchi, Geert J. Schenk, Jeffrey T. Joseph, Jeroen J. G. Geurts, and Peter K. Stys [Early life adversity promotes resilience to opioid addiction-related phenotypes in male rats and sex-specific transcriptional changes]( Evelyn Ordoñes Sanchez, Charlotte C. Bavley, Andre U. Deutschmann, Rachel Carpenter, Drew R. Peterson, Reza Karbalaei, James Flowers II, Charleanne M. Rogers, Miranda G. Langrehr, Cory S. Ardekani, Sydney T. Famularo, Angela R. Bongiovanni, Melissa C. Knouse, Stan B. Floresco, Lisa A. Briand, Mathieu E. Wimmer, and Debra A. Bangasser [Peripheral sensory stimulation elicits global slow waves by recruiting somatosensory cortex bilaterally]( Zachary P. Rosenthal, Ryan V. Raut, Ryan M. Bowen, Abraham Z. Snyder, Joseph P. Culver, Marcus E. Raichle, and Jin-Moo Lee [GFRAL-expressing neurons suppress food intake via aversive pathways]( Paul V. Sabatini, Henriette Frikke-Schmidt, Joe Arthurs, Desiree Gordian, Anita Patel, Alan C. Rupp, Jessica M. Adams, Jine Wang, Sebastian Beck Jørgensen, David P. Olson, Richard D. Palmiter, Martin G. Myers Jr, and Randy J. Seeley [Genetic priming of sensory neurons in mice that overexpress PAR2 enhances allergen responsiveness]( Joao M. Braz, Todd Dembo, Alexandra Charruyer, Ruby Ghadially, Marlys S. Fassett, and Allan I. Basbaum Pharmacology [Modulation of α1β3γ2 GABAA receptors expressed in X. laevis oocytes using a propofol photoswitch tethered to the transmembrane helix]( Cecilia M. Borghese, Hua-Yu L. Wang, Stanton F. McHardy, Robert O. Messing, James R. Trudell, R. Adron Harris, and Edward J. Bertaccini Plant Biology [Tissue folding at the organ–meristem boundary results in nuclear compression and chromatin compaction]( Kateryna Fal, Niklas Korsbo, Juan Alonso-Serra, Jose Teles, Mengying Liu, Yassin Refahi, Marie-Edith Chabouté, Henrik Jönsson, and Olivier Hamant [Mechanism and function of root circumnutation]( Isaiah Taylor, Kevin Lehner, Erin McCaskey, Niba Nirmal, Yasemin Ozkan-Aydin, Mason Murray-Cooper, Rashmi Jain, Elliot W. Hawkes, Pamela C. Ronald, Daniel I. Goldman, and Philip N. Benfey [INTERMEDIUM-M encodes an HvAP2L-H5 ortholog and is required for inflorescence indeterminacy and spikelet determinacy in barley]( Jinshun Zhong, G. Wilma van Esse, Xiaojing Bi, Tianyu Lan, Agatha Walla, Qing Sang, Rainer Franzen, and Maria von Korff [Plant egg cell fate determination depends on its exact position in female gametophyte]( Yang Sun, Xiu Wang, Lin Pan, Fei Xie, Bo Dai, Mengxiang Sun, and Xiongbo Peng [Transcriptional control of local auxin distribution by the CsDFB1-CsPHB module regulates floral organogenesis in cucumber]( Jing Nie, Nan Shan, Huan Liu, Xuehui Yao, Ziwei Wang, Ruoxue Bai, Yicong Guo, Ying Duan, Changlin Wang, and Xiaolei Sui Systems Biology [Emergence of diauxie as an optimal growth strategy under resource allocation constraints in cellular metabolism]( Pierre Salvy and Vassily Hatzimanikatis --------------------------------------------------------------- Corrections Biophysics and Computational Biology [Correction for Rübbelke et al., Locking mixed-lineage kinase domain-like protein in its auto-inhibited state prevents necroptosis]( Medical Sciences, Statistics [Correction for Cippà et al., A data-driven approach to identify risk profiles and protective drugs in COVID-19]( [Cover] --------------------------------------------------------------- This message was sent to {EMAIL}. 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