PNAS Table of Contents for January 5, 2021; Vol. 118, No. 1 is now complete

[PNAS] [Top Ten 2020](/cgi/adclick/?ad=55508&adclick=true&url=https%3A%2F%2Fwww.pnas.org%2Fpage%2Ftoptenstories%2F2020)   [December 14, 2020; Vol. 118, No. 1]( ) Opinion [Opinion: We need to improve the welfare of life science trainees]( Daniele Simoneschi --------------------------------------------------------------- Science and Culture [Science and Culture: Astronomer-turned-filmmaker strives to ignite an interest in space]( Stephen Ornes --------------------------------------------------------------- Retrospective [José Mario Molina: Life and legacy of a man who helped to save Earth’s ozone layer]( Rodolfo Dirzo and Adrián Fernández --------------------------------------------------------------- Commentary [Mobility restrictions are more than transient reduction of travel activities]( Ruiyun Li [Glycomic profiling and the mammalian brain]( Jennyfer Tena and Carlito B. Lebrilla [A field theory for plant tropisms]( Oliver E. Jensen [Navigating the waters of membrane design]( Henry S. Ashbaugh --------------------------------------------------------------- Perspective [On the use of simulation in robotics: Opportunities, challenges, and suggestions for moving forward]( HeeSun Choi, Cindy Crump, Christian Duriez, Asher Elmquist, Gregory Hager, David Han, Frank Hearl, Jessica Hodgins, Abhinandan Jain, Frederick Leve, Chen Li, Franziska Meier, Dan Negrut, Ludovic Righetti, Alberto Rodriguez, Jie Tan, and Jeff Trinkle [Historical natural kinds and mineralogy: Systematizing contingency in the context of necessity]( Carol E. Cleland, Robert M. Hazen, and Shaunna M. Morrison --------------------------------------------------------------- Letters [Metabolites as frailty biomarkers in older adults]( Yiming Pan, Yun Li, and Lina Ma [Reply to Pan et al.: Whole blood metabolome analysis combined with comprehensive frailty assessment]( Masahiro Kameda, Takayuki Teruya, Mitsuhiro Yanagida, and Hiroshi Kondoh [Island species experience higher niche expansion and lower niche conservatism during invasion]( James T. Stroud [Reply to Stroud: Invasive amphibians and reptiles from islands indeed show higher niche expansion than mainland species]( Chunlong Liu, Christian Wolter, Weiwei Xian, and Jonathan M. Jeschke --------------------------------------------------------------- Physical Sciences Applied Physical Sciences [Proton strings and rings in atypical nucleation of ferroelectricity in ice]( J. Lasave, S. Koval, A. Laio, and E. Tosatti [Discovering multiscale and self-similar structure with data-driven wavelets]( Daniel Floryan and Michael D. Graham [PACAP is a pathogen-inducible resident antimicrobial neuropeptide affording rapid and contextual molecular host defense of the brain]( Ernest Y. Lee, Liana C. Chan, Huiyuan Wang, Juelline Lieng, Mandy Hung, Yashes Srinivasan, Jennifer Wang, James A. Waschek, Andrew L. Ferguson, Kuo-Fen Lee, Nannette Y. Yount, Michael R. Yeaman, and Gerard C. L. Wong Chemistry [Strong metal–metal Pauli repulsion leads to repulsive metallophilicity in closed-shell d8 and d10 organometallic complexes]( Qingyun Wan, Jun Yang, Wai-Pong To, and Chi-Ming Che [Affinity of small-molecule solutes to hydrophobic, hydrophilic, and chemically patterned interfaces in aqueous solution]( Jacob I. Monroe, Sally Jiao, R. Justin Davis, Dennis Robinson Brown, Lynn E. Katz, and M. Scott Shell Earth, Atmospheric, and Planetary Sciences [Stochastic dynamics of barrier island elevation]( Orencio Durán Vinent, Benjamin E. Schaffer, and Ignacio Rodriguez-Iturbe [Probabilistic structure of events controlling the after-storm recovery of coastal dunes]( Tobia Rinaldo, Kiran Adhithya Ramakrishnan, Ignacio Rodriguez-Iturbe, and Orencio Durán Vinent [Remnants of early Earth differentiation in the deepest mantle-derived lavas]( Andrea Giuliani, Matthew G. Jackson, Angus Fitzpayne, and Hayden Dalton [Global silicate weathering flux overestimated because of sediment–water cation exchange]( Edward T. Tipper, Emily I. Stevenson, Victoria Alcock, Alasdair C. G. Knight, J. Jotautas Baronas, Robert G. Hilton, Mike J. Bickle, Christina S. Larkin, Linshu Feng, Katy E. Relph, and Genevieve Hughes Engineering [Adipose tissue is a critical regulator of osteoarthritis]( Kelsey H. Collins, Kristin L. Lenz, Eleanor N. Pollitt, Daniel Ferguson, Irina Hutson, Luke E. Springer, Arin K. Oestreich, Ruhang Tang, Yun-Rak Choi, Gretchen A. Meyer, Steven L. Teitelbaum, Christine T. N. Pham, Charles A. Harris, and Farshid Guilak Physics [Tregs self-organize into a computing ecosystem and implement a sophisticated optimization algorithm for mediating immune response]( Robert Marsland III, Owen Howell, Andreas Mayer, and Pankaj Mehta [On conservation laws in quantum mechanics]( Yakir Aharonov, Sandu Popescu, and Daniel Rohrlich Statistics [A data-driven approach to identify risk profiles and protective drugs in COVID-19]( Pietro E. Cippà, Federica Cugnata, Paolo Ferrari, Chiara Brombin, Lorenzo Ruinelli, Giorgia Bianchi, Nicola Beria, Lukas Schulz, Enos Bernasconi, Paolo Merlani, Alessandro Ceschi, and Clelia Di Serio --------------------------------------------------------------- Social Sciences Anthropology [Ancient DNA from Guam and the peopling of the Pacific]( Irina Pugach, Alexander Hübner, Hsiao-chun Hung, Matthias Meyer, Mike T. Carson, and Mark Stoneking Economic Sciences [Nursing home staff networks and COVID-19]( M. Keith Chen, Judith A. Chevalier, and Elisa F. Long [Incorporating ethics and welfare into randomized experiments]( Yusuke Narita Environmental Sciences [Global evidence for ultraviolet radiation decreasing COVID-19 growth rates]( Tamma Carleton, Jules Cornetet, Peter Huybers, Kyle C. Meng, and Jonathan Proctor Psychological and Cognitive Sciences [Transfer of information across repeated decisions in general and in obsessive–compulsive disorder]( Alec Solway, Zhen Lin, and Ekansh Vinaik [Concerns for others increases the likelihood of vaccination against influenza and COVID-19 more in sparsely rather than densely populated areas]( Haesung Jung and Dolores Albarracín Social Sciences [Impacts of the COVID-19 pandemic on rural America]( J. Tom Mueller, Kathryn McConnell, Paul Berne Burow, Katie Pofahl, Alexis A. Merdjanoff, and Justin Farrell [Enforcement may crowd out voluntary support for COVID-19 policies, especially where trust in government is weak and in a liberal society]( Katrin Schmelz [Filling the gaps in the global prevalence map of clinical antimicrobial resistance]( Rik Oldenkamp, Constance Schultsz, Emiliano Mancini, and Antonio Cappuccio --------------------------------------------------------------- Biological Sciences Agricultural Sciences [Transgenic cotton and sterile insect releases synergize eradication of pink bollworm a century after it invaded the United States]( Bruce E. Tabashnik, Leighton R. Liesner, Peter C. Ellsworth, Gopalan C. Unnithan, Jeffrey A. Fabrick, Steven E. Naranjo, Xianchun Li, Timothy J. Dennehy, Larry Antilla, Robert T. Staten, and Yves Carrière Anthropology [Ancient DNA from Guam and the peopling of the Pacific]( Irina Pugach, Alexander Hübner, Hsiao-chun Hung, Matthias Meyer, Mike T. Carson, and Mark Stoneking [Maternal death and offspring fitness in multiple wild primates]( Matthew N. Zipple, Jeanne Altmann, Fernando A. Campos, Marina Cords, Linda M. Fedigan, Richard R. Lawler, Elizabeth V. Lonsdorf, Susan Perry, Anne E. Pusey, Tara S. Stoinski, Karen B. Strier, and Susan C. Alberts Biochemistry [Binding of cardiotonic steroids to Na+,K+-ATPase in the E2P state]( Ryuta Kanai, Flemming Cornelius, Haruo Ogawa, Kanna Motoyama, Bente Vilsen, and Chikashi Toyoshima [Mechanistic insights into the synergistic activation of the RXR–PXR heterodimer by endocrine disruptor mixtures]( Vanessa Delfosse, Tiphaine Huet, Deborah Harrus, Meritxell Granell, Maxime Bourguet, Caroline Gardia-Parège, Barbara Chiavarina, Marina Grimaldi, Sébastien Le Mével, Pauline Blanc, David Huang, Jakub Gruszczyk, Barbara Demeneix, Sarah Cianférani, Jean-Baptiste Fini, Patrick Balaguer, and William Bourguet Biophysics and Computational Biology [A phosphorylation-dependent switch in the disordered p53 transactivation domain regulates DNA binding]( Xun Sun, H. Jane Dyson, and Peter E. Wright [Structural and molecular basis of cross-seeding barriers in amyloids]( Asen Daskalov, Denis Martinez, Virginie Coustou, Nadia El Mammeri, Mélanie Berbon, Loren B. Andreas, Benjamin Bardiaux, Jan Stanek, Abdelmajid Noubhani, Brice Kauffmann, Joseph S. Wall, Guido Pintacuda, Sven J. Saupe, Birgit Habenstein, and Antoine Loquet [Deep learning for in vivo near-infrared imaging]( Zhuoran Ma, Feifei Wang, Weizhi Wang, Yeteng Zhong, and Hongjie Dai Cell Biology [The Ligand of Ate1 is intrinsically disordered and participates in nucleolar phase separation regulated by Jumonji Domain Containing 6]( Akshaya Arva, Yasar Arfat T. Kasu, Jennifer Duncan, Mosleh A. Alkhatatbeh, and Christopher S. Brower [In vitro reconstitution reveals phosphoinositides as cargo-release factors and activators of the ARF6 GAP ADAP1]( Christian Duellberg, Albert Auer, Nikola Canigova, Katrin Loibl, and Martin Loose [Downregulation of autophagy by Met30-mediated Atg9 ubiquitination]( Yuchen Feng, Aileen R. Ariosa, Ying Yang, Zehan Hu, Jörn Dengjel, and Daniel J. Klionsky [Evolutionarily related small viral fusogens hijack distinct but modular actin nucleation pathways to drive cell-cell fusion]( Ka Man Carmen Chan, Ashley L. Arthur, Johannes Morstein, Meiyan Jin, Abrar Bhat, Dörte Schlesinger, Sungmin Son, Donté A. Stevens, David G. Drubin, and Daniel A. Fletcher [Extrasynaptic acetylcholine signaling through a muscarinic receptor regulates cell migration]( Mihoko Kato, Irina Kolotuev, Alexandre Cunha, Shahla Gharib, and Paul W. Sternberg Developmental Biology [Maternal GABAergic and GnRH/corazonin pathway modulates egg diapause phenotype of the silkworm Bombyx mori]( Ryoma Tsuchiya, Aino Kaneshima, Masakazu Kobayashi, Maki Yamazaki, Yoko Takasu, Hideki Sezutsu, Yoshiaki Tanaka, Akira Mizoguchi, and Kunihiro Shiomi [GATA6 is a regulator of sinus node development and heart rhythm]( Lara Gharibeh, Abir Yamak, Jamieson Whitcomb, Aizhu Lu, Mathieu Joyal, Hiba Komati, Wenbin Liang, Céline Fiset, and Mona Nemer Ecology [Microrheology reveals microscale viscosity gradients in planktonic systems]( Òscar Guadayol, Tania Mendonca, Mariona Segura-Noguera, Amanda J. Wright, Manlio Tassieri, and Stuart Humphries Environmental Sciences [Global evidence for ultraviolet radiation decreasing COVID-19 growth rates]( Tamma Carleton, Jules Cornetet, Peter Huybers, Kyle C. Meng, and Jonathan Proctor Evolution [Mammalian molar complexity follows simple, predictable patterns]( Keegan R. Selig, Waqqas Khalid, and Mary T. Silcox [The evolution of skin pigmentation-associated variation in West Eurasia]( Dan Ju and Iain Mathieson [Single-molecule nanopore sequencing reveals extreme target copy number heterogeneity in arylomycin-resistant mutants]( Hany S. Girgis, Cory D. DuPai, Jessica Lund, Janina Reeder, Joseph Guillory, Steffen Durinck, Yuxin Liang, Joshua Kaminker, Peter A. Smith, and Elizabeth Skippington Genetics [Genome-wide surveillance of transcription errors in response to genotoxic stress]( C. Fritsch, J.-F. Gout, S. Haroon, A. Towheed, C. Chung, J. LaGosh, E. McGann, X. Zhang, Y. Song, S. Simpson, P. S. Danthi, B. A. Benayoun, D. Wallace, K. Thomas, M. Lynch, and M. Vermulst [Mfd regulates RNA polymerase association with hard-to-transcribe regions in vivo, especially those with structured RNAs]( Mark N. Ragheb, Christopher Merrikh, Kaitlyn Browning, and Houra Merrikh [Precise genome engineering in Drosophila using prime editing]( Justin A. Bosch, Gabriel Birchak, and Norbert Perrimon Immunology and Inflammation [Host fibrinogen drives antimicrobial function in Staphylococcus aureus peritonitis through bacterial-mediated prothrombin activation]( Joni M. Prasad, Oscar Negrón, Xinli Du, Eric S. Mullins, Joseph S. Palumbo, Jessica M. Gilbertie, Magnus Höök, Steven P. Grover, Rafal Pawlinski, Nigel Mackman, Jay L. Degen, and Matthew J. Flick [Cigarette smoke induces miR-132 in Th17 cells that enhance osteoclastogenesis in inflammatory arthritis]( Paula B. Donate, Kalil Alves de Lima, Raphael S. Peres, Fausto Almeida, Sandra Y. Fukada, Tarcilia A. Silva, Daniele C. Nascimento, Nerry T. Cecilio, Jhimmy Talbot, Rene D. Oliveira, Geraldo A. Passos, José Carlos Alves-Filho, Thiago M. Cunha, Paulo Louzada-Junior, Foo Y. Liew, and Fernando Q. Cunha [HMGB1-mediated chromatin remodeling attenuates Il24 gene expression for the protection from allergic contact dermatitis]( Naoyuki Senda, Hideyuki Yanai, Sana Hibino, Lei Li, Yu Mizushima, Tomomitsu Miyagaki, Mai Saeki, Yusuke Kishi, Sho Hangai, Junko Nishio, Makoto Sugaya, Tadatsugu Taniguchi, and Shinichi Sato [Recruitment of pro-IL-1α to mitochondrial cardiolipin, via shared LC3 binding domain, inhibits mitophagy and drives maximal NLRP3 activation]( Jargalsaikhan Dagvadorj, Karolina Mikulska-Ruminska, Gantsetseg Tumurkhuu, Rojo A. Ratsimandresy, Jessica Carriere, Allen M. Andres, Stefanie Marek-Iannucci, Yang Song, Shuang Chen, Malcolm Lane, Andrea Dorfleutner, Roberta A. Gottlieb, Christian Stehlik, Suzanne Cassel, Fayyaz S. Sutterwala, Ivet Bahar, Timothy R. Crother, and Moshe Arditi [UFMylation inhibits the proinflammatory capacity of interferon-γ–activated macrophages]( Dale R. Balce, Ya-Ting Wang, Michael R. McAllaster, Bria F. Dunlap, Anthony Orvedahl, Barry L. Hykes Jr, Lindsay Droit, Scott A. Handley, Craig B. Wilen, John G. Doench, Robert C. Orchard, Christina L. Stallings, and Herbert W. Virgin [Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity]( Patrick Ostkamp, Anke Salmen, Béatrice Pignolet, Dennis Görlich, Till F. M. Andlauer, Andreas Schulte-Mecklenbeck, Gabriel Gonzalez-Escamilla, Florence Bucciarelli, Isabelle Gennero, Johanna Breuer, Gisela Antony, Tilman Schneider-Hohendorf, Nadine Mykicki, Antonios Bayas, Florian Then Bergh, Stefan Bittner, Hans-Peter Hartung, Manuel A. Friese, Ralf A. Linker, Felix Luessi, Klaus Lehmann-Horn, Mark Mühlau, Friedemann Paul, Martin Stangel, Björn Tackenberg, Hayrettin Tumani, Clemens Warnke, Frank Weber, Brigitte Wildemann, Uwe K. Zettl, Ulf Ziemann, Bertram Müller-Myhsok, Tania Kümpfel, Luisa Klotz, Sven G. Meuth, Frauke Zipp, Bernhard Hemmer, Reinhard Hohlfeld, David Brassat, Ralf Gold, Catharina C. Gross, Carsten Lukas, Sergiu Groppa, Karin Loser, Heinz Wiendl, Nicholas Schwab, and on behalf of the German Competence Network Multiple Sclerosis (KKNMS) and the BIONAT Network [Two populations of self-maintaining monocyte-independent macrophages exist in adult epididymis and testis]( Ming Wang, Yalong Yang, Dilay Cansever, Yiming Wang, Crystal Kantores, Sébastien Messiaen, Delphine Moison, Gabriel Livera, Svetoslav Chakarov, Tobias Weinberger, Christopher Stremmel, Monika Fijak, Britta Klein, Christiane Pleuger, Zhexiong Lian, Wentao Ma, Qingzhi Liu, Kathrin Klee, Kristian Händler, Thomas Ulas, Andreas Schlitzer, Joachim L. Schultze, Burkhard Becher, Melanie Greter, Zhaoyuan Liu, Florent Ginhoux, Slava Epelman, Christian Schulz, Andreas Meinhardt, and Sudhanshu Bhushan [PACAP is a pathogen-inducible resident antimicrobial neuropeptide affording rapid and contextual molecular host defense of the brain]( Ernest Y. Lee, Liana C. Chan, Huiyuan Wang, Juelline Lieng, Mandy Hung, Yashes Srinivasan, Jennifer Wang, James A. Waschek, Andrew L. Ferguson, Kuo-Fen Lee, Nannette Y. Yount, Michael R. Yeaman, and Gerard C. L. Wong Medical Sciences [A data-driven approach to identify risk profiles and protective drugs in COVID-19]( Pietro E. Cippà, Federica Cugnata, Paolo Ferrari, Chiara Brombin, Lorenzo Ruinelli, Giorgia Bianchi, Nicola Beria, Lukas Schulz, Enos Bernasconi, Paolo Merlani, Alessandro Ceschi, and Clelia Di Serio [Targeting transcriptional regulation of SARS-CoV-2 entry factors ACE2 and TMPRSS2]( Yuanyuan Qiao, Xiao-Ming Wang, Rahul Mannan, Sethuramasundaram Pitchiaya, Yuping Zhang, Jesse W. Wotring, Lanbo Xiao, Dan R. Robinson, Yi-Mi Wu, Jean Ching-Yi Tien, Xuhong Cao, Stephanie A. Simko, Ingrid J. Apel, Pushpinder Bawa, Steven Kregel, Sathiya P. Narayanan, Gregory Raskind, Stephanie J. Ellison, Abhijit Parolia, Sylvia Zelenka-Wang, Lisa McMurry, Fengyun Su, Rui Wang, Yunhui Cheng, Andrew D. Delekta, Zejie Mei, Carla D. Pretto, Shaomeng Wang, Rohit Mehra, Jonathan Z. Sexton, and Arul M. Chinnaiyan [Adaptive responses to mTOR gene targeting in hematopoietic stem cells reveal a proliferative mechanism evasive to mTOR inhibition]( Cuiqing Fan, Chuntao Zhao, Feng Zhang, Meenu Kesarwani, Zhaowei Tu, Xiongwei Cai, Ashley Kuenzi Davis, Lingli Xu, Cindy L. Hochstetler, Xiaoyi Chen, Fukun Guo, Gang Huang, Mohammad Azam, Weidong Tian, Q. Richard Lu, and Yi Zheng [Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22]( Qinglan Wang, So Yeon Kim, Hiroshi Matsushita, Zhijun Wang, Vijay Pandyarajan, Michitaka Matsuda, Koichiro Ohashi, Takashi Tsuchiya, Yoon Seok Roh, Calvin Kiani, Yutong Zhao, Michael Chan, Suzanne Devkota, Shelly C. Lu, Tomoko Hayashi, Dennis A. Carson, and Ekihiro Seki [Pharmacokinetic modeling reveals parameters that govern tumor targeting and delivery by a pH-Low Insertion Peptide (pHLIP)]( Alexander A. Svoronos and Donald M. Engelman [A protease-activated, near-infrared fluorescent probe for early endoscopic detection of premalignant gastrointestinal lesions]( Joshua J. Yim, Stefan Harmsen, Krzysztof Flisikowski, Tatiana Flisikowska, Hong Namkoong, Megan Garland, Nynke S. van den Berg, José G. Vilches-Moure, Angelika Schnieke, Dieter Saur, Sarah Glasl, Dimitris Gorpas, Aida Habtezion, Vasilis Ntziachristos, Christopher H. Contag, Sanjiv S. Gambhir, Matthew Bogyo, and Stephan Rogalla Microbiology [Cryo-EM structure of the full-length WzmWzt ABC transporter required for lipid-linked O antigen transport]( Christopher A. Caffalette and Jochen Zimmer [Cross-species recognition of SARS-CoV-2 to bat ACE2]( Kefang Liu, Shuguang Tan, Sheng Niu, Jia Wang, Lili Wu, Huan Sun, Yanfang Zhang, Xiaoqian Pan, Xiao Qu, Pei Du, Yumin Meng, Yunfei Jia, Qian Chen, Chuxia Deng, Jinghua Yan, Hong-Wei Wang, Qihui Wang, Jianxun Qi, and George Fu Gao [Endogenous membrane stress induces T6SS activity in Pseudomonas aeruginosa]( Anne-Sophie Stolle, Bradley Thomas Meader, Jonida Toska, and John J. Mekalanos [E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes]( Stephanie L. Sarbanes, Vincent A. Blomen, Eric Lam, Søren Heissel, Joseph M. Luna, Thijn R. Brummelkamp, Erik Falck-Pedersen, H.-Heinrich Hoffmann, and Charles M. Rice [The retromer is co-opted to deliver lipid enzymes for the biogenesis of lipid-enriched tombusviral replication organelles]( Zhike Feng, Jun-ichi Inaba, and Peter D. Nagy [Staphylococcus aureus binds to the N-terminal region of corneodesmosin to adhere to the stratum corneum in atopic dermatitis]( Aisling M. Towell, Cécile Feuillie, Pauline Vitry, Thaina M. Da Costa, Marion Mathelié-Guinlet, Sanja Kezic, Orla M. Fleury, Maeve A. McAleer, Yves F. Dufrêne, Alan D. Irvine, and Joan A. Geoghegan Neuroscience [Environmental noise degrades hippocampus-related learning and memory]( Yifan Zhang, Min Zhu, Yutian Sun, Binliang Tang, Guimin Zhang, Pengying An, Yuan Cheng, Ye Shan, Michael M. Merzenich, and Xiaoming Zhou [Prioritized experience replays on a hippocampal predictive map for learning]( Hideyoshi Igata, Yuji Ikegaya, and Takuya Sasaki [Transfer of information across repeated decisions in general and in obsessive–compulsive disorder]( Alec Solway, Zhen Lin, and Ekansh Vinaik [Astrocyte-secreted IL-33 mediates homeostatic synaptic plasticity in the adult hippocampus]( Ye Wang, Wing-Yu Fu, Kit Cheung, Kwok-Wang Hung, Congping Chen, Hongyan Geng, Wing-Ho Yung, Jianan Y. Qu, Amy K. Y. Fu, and Nancy Y. Ip [Primary cilia safeguard cortical neurons in neonatal mouse forebrain from environmental stress-induced dendritic degeneration]( Seiji Ishii, Toru Sasaki, Shahid Mohammad, Hye Hwang, Edwin Tomy, Fahad Somaa, Nobuyuki Ishibashi, Hideyuki Okano, Pasko Rakic, Kazue Hashimoto-Torii, and Masaaki Torii [A genome-wide microRNA screen identifies the microRNA-183/96/182 cluster as a modulator of circadian rhythms]( Lili Zhou, Caitlyn Miller, Loren J. Miraglia, Angelica Romero, Ludovic S. Mure, Satchidananda Panda, and Steve A. Kay [Social isolation uncovers a circuit underlying context-dependent territory-covering micturition]( Minsuk Hyun, Julian Taranda, Gianna Radeljic, Lauren Miner, Wengang Wang, Nicole Ochandarena, Kee Wui Huang, Pavel Osten, and Bernardo L. Sabatini [Association of aerobic glycolysis with the structural connectome reveals a benefit–risk balancing mechanism in the human brain]( Yuhan Chen, Qixiang Lin, Xuhong Liao, Changsong Zhou, and Yong He [Nitric oxide resets kisspeptin-excited GnRH neurons via PIP2 replenishment]( Stephanie Constantin, Daniel Reynolds, Andrew Oh, Katherine Pizano, and Susan Wray [The Parkinson’s disease-associated gene ITPKB protects against α-synuclein aggregation by regulating ER-to-mitochondria calcium release]( Daniel J. Apicco, Evgeny Shlevkov, Catherine L. Nezich, David T. Tran, Edward Guilmette, Justin W. Nicholatos, Collin M. Bantle, Yi Chen, Kelly E. Glajch, Neeta A. Abraham, Lan T. Dang, G. Campbell Kaynor, Ellen A. Tsai, Khanh-Dung H. Nguyen, Joost Groot, YuTing Liu, Andreas Weihofen, Jessica A. Hurt, Heiko Runz, and Warren D. Hirst [Filling the gaps in the global prevalence map of clinical antimicrobial resistance]( Rik Oldenkamp, Constance Schultsz, Emiliano Mancini, and Antonio Cappuccio Physiology [Drosophila melanogaster sex peptide regulates mated female midgut morphology and physiology]( Melissa A. White, Alessandro Bonfini, Mariana F. Wolfner, and Nicolas Buchon Plant Biology [Endoplasmic reticulum membrane receptors of the GET pathway are conserved throughout eukaryotes]( Lisa Yasmin Asseck, Dietmar Gerald Mehlhorn, Jhon Rivera Monroy, Martiniano Maria Ricardi, Holger Breuninger, Niklas Wallmeroth, Kenneth Wayne Berendzen, Minou Nowrousian, Shuping Xing, Blanche Schwappach, Martin Bayer, and Christopher Grefen [Evidence for root adaptation to a spatially discontinuous water availability in the absence of external water potential gradients]( Kara R. Lind, Oskar Siemianowski, Bin Yuan, Tom Sizmur, Hannah VanEvery, Souvik Banerjee, and Ludovico Cademartiri [MdERDL6-mediated glucose efflux to the cytosol promotes sugar accumulation in the vacuole through up-regulating TSTs in apple and tomato]( Lingcheng Zhu, Baiyun Li, Limin Wu, Huixia Li, Zhengyang Wang, Xiaoyu Wei, Baiquan Ma, Yanfeng Zhang, Fengwang Ma, Yong-Ling Ruan, and Mingjun Li [Naphthylphthalamic acid associates with and inhibits PIN auxin transporters]( Lindy Abas, Martina Kolb, Johannes Stadlmann, Dorina P. Janacek, Kristina Lukic, Claus Schwechheimer, Leonid A. Sazanov, Lukas Mach, Jiří Friml, and Ulrich Z. Hammes [ROS and hypoxia signaling regulate periodic metabolic arousal during insect dormancy to coordinate glucose, amino acid, and lipid metabolism]( Chao Chen, Rohit Mahar, Matthew E. Merritt, David L. Denlinger, and Daniel A. Hahn [Cellular transduction of mechanical oscillations in plants by the plasma-membrane mechanosensitive channel MSL10]( Daniel Tran, Tiffanie Girault, Marjorie Guichard, Sébastien Thomine, Nathalie Leblanc-Fournier, Bruno Moulia, Emmanuel de Langre, Jean-Marc Allain, and Jean-Marie Frachisse Psychological and Cognitive Sciences [Discrimination and anxiety: Using multiple polygenic scores to control for genetic liability]( Adolfo G. Cuevas, Frank D. Mann, David R. Williams, and Robert F. Krueger --------------------------------------------------------------- SI Correction [Correction to Supporting Information for Kim and Kim, Prediction of inherited genomic susceptibility to 20 common cancer types by a supervised machine-learning method]( [Cover] --------------------------------------------------------------- This message was sent to {EMAIL}. [Unsubscribe]( from or [edit]( your subscription for this service. 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