[PNAS] [Cozzarelli Prize Nominations](/cgi/adclick/?ad=55381&adclick=true&url=https%3A%2F%2Fwww.pnas.org%2Fpage%2Fabout%2Fcozzarelli-prize) Â [November 17, 2020; Vol. 117, No. 46](
) This Week in PNAS
[In This Issue]( This week's research highlights
--------------------------------------------------------------- Opinion
[Opinion: For now, it’s unethical to use human challenge studies for SARS-CoV-2 vaccine development](
Jeffrey P. Kahn, Leslie Meltzer Henry, Anna C. Mastroianni, Wilbur H. Chen, and Ruth Macklin
Leading scientists discuss current issues
--------------------------------------------------------------- Profile
[Profile of Masayori Inouye](
Jennifer Viegas
The life and work of NAS members
--------------------------------------------------------------- Commentaries
[A breakthrough in understanding the molecular basis of coral heat tolerance](
Madeleine J. H. van Oppen and John G. Oakeshott
[Predicting an epidemic trajectory is difficult](
Claus O. Wilke and Carl T. Bergstrom
[Neural polarization and routes to depolarization](
Samantha L. Moore-Berg, Jacob M. Parelman, Yphtach Lelkes, and Emily B. Falk --------------------------------------------------------------- Perspective
[Overkill, glacial history, and the extinction of North America’s Ice Age megafauna](
David J. Meltzer --------------------------------------------------------------- Letters
[Too early to declare a general law of social mobility and heritability for education](
Damien Morris
[Reply to Morris: Heritability of education remains associated with social mobility](
Per Engzell and Felix C. Tropf
[Locomotor and taxonomic diversity of Sterkfontein hominins not supported by current trabecular evidence of the femoral head](
Martin Haeusler, Nicole M. Webb, Viktoria A. Krenn, and Cinzia Fornai
[Reply to Haeusler et al.: Internal structure of the femur provides robust evidence for locomotor and taxonomic diversity at Sterkfontein](
Matthew M. Skinner, Leoni Georgiou, Dominic Stratford, Christopher J. Dunmore, Ameline Bardo, Laura T. Buck, Jean-Jacques Hublin, Dieter H. Pahr, Alexander Synek, and Tracy L. Kivell --------------------------------------------------------------- Brief Reports
[Human Argonaute2 and Argonaute3 are catalytically activated by different lengths of guide RNA](
Mi Seul Park, GeunYoung Sim, Audrey C. Kehling, and Kotaro Nakanishi
[Optogenetic regulation of embryo implantation in mice using photoactivatable CRISPR-Cas9](
Tomoka Takao, Moritoshi Sato, and Tetsuo Maruyama --------------------------------------------------------------- Physical Sciences
Applied Mathematics
[Narrative structure of A Song of Ice and Fire creates a fictional world with realistic measures of social complexity](
Thomas Gessey-Jones, Colm Connaughton, Robin Dunbar, Ralph Kenna, Pádraig MacCarron, Cathal O’Conchobhair, and Joseph Yose Applied Physical Sciences
[Interface and surface stabilization of the polarization in ferroelectric thin films](
Chiara Gattinoni, Nives Strkalj, Rea Härdi, Manfred Fiebig, Morgan Trassin, and Nicola A. Spaldin
[Unraveling intrinsic correlation effects with angle-resolved photoemission spectroscopy](
Jianqiang Sky Zhou, Lucia Reining, Alessandro Nicolaou, Azzedine Bendounan, Kari Ruotsalainen, Marco Vanzini, J. J. Kas, J. J. Rehr, Matthias Muntwiler, Vladimir N. Strocov, Fausto Sirotti, and Matteo Gatti
[Role of inner solvation sheath within salt–solvent complexes in tailoring electrode/electrolyte interphases for lithium metal batteries](
Xiaodi Ren, Peiyuan Gao, Lianfeng Zou, Shuhong Jiao, Xia Cao, Xianhui Zhang, Hao Jia, Mark H. Engelhard, Bethany E. Matthews, Haiping Wu, Hongkyung Lee, Chaojiang Niu, Chongmin Wang, Bruce W. Arey, Jie Xiao, Jun Liu, Ji-Guang Zhang, and Wu Xu Biophysics and Computational Biology
[Protein crowding mediates membrane remodeling in upstream ESCRT-induced formation of intraluminal vesicles](
Susanne Liese, Eva Maria Wenzel, Ingrid Kjos, Rossana Rojas Molina, Sebastian W. Schultz, Andreas Brech, Harald Stenmark, Camilla Raiborg, and Andreas Carlson
[Hedgehog pathway activation through nanobody-mediated conformational blockade of the Patched sterol conduit](
Yunxiao Zhang, Wan-Jin Lu, David P. Bulkley, Jiahao Liang, Arthur Ralko, Shuo Han, Kelsey J. Roberts, Anping Li, Wonhwa Cho, Yifan Cheng, Aashish Manglik, and Philip A. Beachy Chemistry
[Evidence for aggregation-independent, PrPC-mediated Aβ cellular internalization](
Alejandro R. Foley, Graham P. Roseman, Ka Chan, Amanda Smart, Thomas S. Finn, Kevin Yang, R. Scott Lokey, Glenn L. Millhauser, and Jevgenij A. Raskatov
[In situ imaging of two-dimensional surface growth reveals the prevalence and role of defects in zeolite crystallization](
Madhuresh K. Choudhary, Rishabh Jain, and Jeffrey D. Rimer Earth, Atmospheric, and Planetary Sciences
[Outdoor air pollution in India is not only an urban problem](
A. R. Ravishankara, Liji M. David, Jeffrey R. Pierce, and Chandra Venkataraman
[Greigite (Fe3S4) is thermodynamically stable: Implications for its terrestrial and planetary occurrence](
Tamilarasan Subramani, Kristina Lilova, Mykola Abramchuk, Kurt D. Leinenweber, and Alexandra Navrotsky
[Lagged atmospheric circulation response in the Black Sea region to Greenland Interstadial 10](
Markus Czymzik, Norbert R. Nowaczyk, Olaf Dellwig, Antje Wegwerth, Raimund Muscheler, Marcus Christl, and Helge W. Arz
[Early life of Neanderthals](
Alessia Nava, Federico Lugli, Matteo Romandini, Federica Badino, David Evans, Angela H. Helbling, Gregorio Oxilia, Simona Arrighi, Eugenio Bortolini, Davide Delpiano, Rossella Duches, Carla Figus, Alessandra Livraghi, Giulia Marciani, Sara Silvestrini, Anna Cipriani, Tommaso Giovanardi, Roberta Pini, Claudio Tuniz, Federico Bernardini, Irene Dori, Alfredo Coppa, Emanuela Cristiani, Christopher Dean, Luca Bondioli, Marco Peresani, Wolfgang MĂĽller, and Stefano Benazzi Engineering
[Mechanically superior matrices promote osteointegration and regeneration of anterior cruciate ligament tissue in rabbits](
Paulos Y. Mengsteab, Takayoshi Otsuka, Aneesah McClinton, Nikoo Saveh Shemshaki, Shiv Shah, Ho-Man Kan, Elifho Obopilwe, Anthony T. Vella, Lakshmi S. Nair, and Cato T. Laurencin
[In situ sprayed NIR-responsive, analgesic black phosphorus-based gel for diabetic ulcer treatment](
Jiang Ouyang, Xiaoyuan Ji, Xingcai Zhang, Chan Feng, Zhongmin Tang, Na Kong, Angel Xie, Junqing Wang, Xinbing Sui, Liu Deng, Younian Liu, Jong Seung Kim, Yihai Cao, and Wei Tao
[Mechanical injuries of neurons induce tau mislocalization to dendritic spines and tau-dependent synaptic dysfunction](
Nicholas J. Braun, Katherine R. Yao, Patrick W. Alford, and Dezhi Liao --------------------------------------------------------------- Social Sciences
Anthropology
[Narrative structure of A Song of Ice and Fire creates a fictional world with realistic measures of social complexity](
Thomas Gessey-Jones, Colm Connaughton, Robin Dunbar, Ralph Kenna, Pádraig MacCarron, Cathal O’Conchobhair, and Joseph Yose Economic Sciences
[Voluntary restrictions on self-reliance increase cooperation and mitigate wealth inequality](
Jörg Gross and Robert Böhm Environmental Sciences
[Outdoor air pollution in India is not only an urban problem](
A. R. Ravishankara, Liji M. David, Jeffrey R. Pierce, and Chandra Venkataraman Political Sciences
[Exposure to news grows less fragmented with an increase in mobile access](
Tian Yang, SĂlvia MajĂł-Vázquez, Rasmus K. Nielsen, and Sandra González-BailĂłn Psychological and Cognitive Sciences
[The rise of prosociality in fiction preceded democratic revolutions in Early Modern Europe](
Mauricio de Jesus Dias Martins and Nicolas Baumard Social Sciences
[Government effectiveness and institutions as determinants of tropical cyclone mortality](
Elizabeth Tennant and Elisabeth A. Gilmore Sustainability Science
[Geographies of insecure water access and the housing–water nexus in US cities](
Katie Meehan, Jason R. Jurjevich, Nicholas M. J. W. Chun, and Justin Sherrill --------------------------------------------------------------- Biological Sciences
Agricultural Sciences
[Copy number variation of TdDof controls solid-stemmed architecture in wheat](
Kirby T. Nilsen, Sean Walkowiak, Daoquan Xiang, Peng Gao, Teagen D. Quilichini, Ian R. Willick, Brook Byrns, Amidou N’Diaye, Jennifer Ens, Krystalee Wiebe, Yuefeng Ruan, Richard D. Cuthbert, Melanie Craze, Emma J. Wallington, James Simmonds, Cristobal Uauy, Raju Datla, and Curtis J. Pozniak Anthropology
[Early life of Neanderthals](
Alessia Nava, Federico Lugli, Matteo Romandini, Federica Badino, David Evans, Angela H. Helbling, Gregorio Oxilia, Simona Arrighi, Eugenio Bortolini, Davide Delpiano, Rossella Duches, Carla Figus, Alessandra Livraghi, Giulia Marciani, Sara Silvestrini, Anna Cipriani, Tommaso Giovanardi, Roberta Pini, Claudio Tuniz, Federico Bernardini, Irene Dori, Alfredo Coppa, Emanuela Cristiani, Christopher Dean, Luca Bondioli, Marco Peresani, Wolfgang MĂĽller, and Stefano Benazzi Applied Biological Sciences
[Mechanically superior matrices promote osteointegration and regeneration of anterior cruciate ligament tissue in rabbits](
Paulos Y. Mengsteab, Takayoshi Otsuka, Aneesah McClinton, Nikoo Saveh Shemshaki, Shiv Shah, Ho-Man Kan, Elifho Obopilwe, Anthony T. Vella, Lakshmi S. Nair, and Cato T. Laurencin
[In situ sprayed NIR-responsive, analgesic black phosphorus-based gel for diabetic ulcer treatment](
Jiang Ouyang, Xiaoyuan Ji, Xingcai Zhang, Chan Feng, Zhongmin Tang, Na Kong, Angel Xie, Junqing Wang, Xinbing Sui, Liu Deng, Younian Liu, Jong Seung Kim, Yihai Cao, and Wei Tao Biochemistry
[Evidence for aggregation-independent, PrPC-mediated Aβ cellular internalization](
Alejandro R. Foley, Graham P. Roseman, Ka Chan, Amanda Smart, Thomas S. Finn, Kevin Yang, R. Scott Lokey, Glenn L. Millhauser, and Jevgenij A. Raskatov
[Redox-mediated regulation of an evolutionarily conserved cross-β structure formed by the TDP43 low complexity domain](
Yi Lin, Xiaoming Zhou, Masato Kato, Daifei Liu, Sina Ghaemmaghami, Benjamin P. Tu, and Steven L. McKnight
[Chlorovirus PBCV-1 protein A064R has three of the transferase activities necessary to synthesize its capsid protein N-linked glycans](
Immacolata Speciale, Maria Elena Laugieri, Eric Noel, Sicheng Lin, Todd L. Lowary, Antonio Molinaro, Garry A. Duncan, Irina V. Agarkova, Domenico Garozzo, Michela G. Tonetti, James L. Van Etten, and Cristina De Castro
[Spatial and temporal diversity of glycome expression in mammalian brain](
Jua Lee, Seungshin Ha, Minsoo Kim, Seong-Wook Kim, Jaekyung Yun, Sureyya Ozcan, Heeyoun Hwang, In Jung Ji, Dongtan Yin, Maree J. Webster, Cynthia Shannon Weickert, Jae-Han Kim, Jong Shin Yoo, Rudolf Grimm, Sabine Bahn, Hee-Sup Shin, and Hyun Joo An
[The MscS-like channel YnaI has a gating mechanism based on flexible pore helices](
Vanessa Judith Flegler, Akiko Rasmussen, Shanlin Rao, Na Wu, Renato Zenobi, Mark S. P. Sansom, Rainer Hedrich, Tim Rasmussen, and Bettina Böttcher
[Receptor tyrosine kinases activate heterotrimeric G proteins via phosphorylation within the interdomain cleft of Gαi](
Nicholas A. Kalogriopoulos, Inmaculada Lopez-Sanchez, Changsheng Lin, Tony Ngo, Krishna K. Midde, Suchismita Roy, Nicolas Aznar, Fiona Murray, Mikel Garcia-Marcos, Irina Kufareva, Majid Ghassemian, and Pradipta Ghosh Biophysics and Computational Biology
[Exposing the distinctive modular behavior of β-strands and α-helices in folded proteins](
Huabing Wang, Derek T. Logan, Jens Danielsson, and Mikael Oliveberg
[Dissecting heterogeneous cell populations across drug and disease conditions with PopAlign](
Sisi Chen, Paul Rivaud, Jong H. Park, Tiffany Tsou, Emeric Charles, John R. Haliburton, Flavia Pichiorri, and Matt Thomson
[Comparative roles of charge, π, and hydrophobic interactions in sequence-dependent phase separation of intrinsically disordered proteins](
Suman Das, Yi-Hsuan Lin, Robert M. Vernon, Julie D. Forman-Kay, and Hue Sun Chan Cell Biology
[Protein crowding mediates membrane remodeling in upstream ESCRT-induced formation of intraluminal vesicles](
Susanne Liese, Eva Maria Wenzel, Ingrid Kjos, Rossana Rojas Molina, Sebastian W. Schultz, Andreas Brech, Harald Stenmark, Camilla Raiborg, and Andreas Carlson
[Akt3 induces oxidative stress and DNA damage by activating the NADPH oxidase via phosphorylation of p47phox](
Christos Polytarchou, Maria Hatziapostolou, Tung On Yau, Niki Christodoulou, Philip W. Hinds, Filippos Kottakis, Ioannis Sanidas, and Philip N. Tsichlis
[Daily mitochondrial dynamics in cone photoreceptors](
Michelle M. Giarmarco, Daniel C. Brock, Brian M. Robbings, Whitney M. Cleghorn, Kristine A. Tsantilas, Kellie C. Kuch, William Ge, Kaitlyn M. Rutter, Edward D. Parker, James B. Hurley, and Susan E. Brockerhoff
[β-Catenin signaling dynamics regulate cell fate in differentiating neural stem cells](
Alyssa B. Rosenbloom, Marcin Tarczyński, Nora Lam, Ravi S. Kane, Lukasz J. Bugaj, and David V. Schaffer Developmental Biology
[Hedgehog pathway activation through nanobody-mediated conformational blockade of the Patched sterol conduit](
Yunxiao Zhang, Wan-Jin Lu, David P. Bulkley, Jiahao Liang, Arthur Ralko, Shuo Han, Kelsey J. Roberts, Anping Li, Wonhwa Cho, Yifan Cheng, Aashish Manglik, and Philip A. Beachy
[CHD7 regulates cardiovascular development through ATP-dependent and -independent activities](
Shun Yan, Rassarin Thienthanasit, Dongquan Chen, Erik Engelen, Joanna BrĂĽhl, David K. Crossman, Robert Kesterson, Qin Wang, Karim Bouazoune, and Kai Jiao Ecology
[Virulence mismatches in index hosts shape the outcomes of cross-species transmission](
Nardus Mollentze, Daniel G. Streicker, Pablo R. Murcia, Katie Hampson, and Roman Biek Evolution
[The rise of angiosperms pushed conifers to decline during global cooling](
Fabien L. Condamine, Daniele Silvestro, Eva B. Koppelhus, and Alexandre Antonelli
[Distance metrics for ranked evolutionary trees](
Jaehee Kim, Noah A. Rosenberg, and Julia A. Palacios
[Two centuries of monarch butterfly collections reveal contrasting effects of range expansion and migration loss on wing traits](
Micah G. Freedman, Hugh Dingle, Sharon Y. Strauss, and Santiago R. RamĂrez
[The evolution of altruism and the serial rediscovery of the role of relatedness](
Tomas Kay, Laurent Keller, and Laurent Lehmann Genetics
[Evolution of the genetic code; Evidence from serine codon use disparity in Escherichia coli](
Masayori Inouye, Risa Takino, Yojiro Ishida, and Keiko Inouye
[Reduced thermal tolerance in a coral carrying CRISPR-induced mutations in the gene for a heat-shock transcription factor](
Phillip A. Cleves, Amanda I. Tinoco, Jacob Bradford, Dimitri Perrin, Line K. Bay, and John R. Pringle
[Insights into coral bleaching under heat stress from analysis of gene expression in a sea anemone model system](
Phillip A. Cleves, Cory J. Krediet, Erik M. Lehnert, Masayuki Onishi, and John R. Pringle
[REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks](
Nimrat Chatterjee, Matthew A. Whitman, Cynthia A. Harris, Sophia M. Min, Oliver Jonas, Evan C. Lien, Alba Luengo, Matthew G. Vander Heiden, Jiyong Hong, Pei Zhou, Michael T. Hemann, and Graham C. Walker
[Rev7 loss alters cisplatin response and increases drug efficacy in chemotherapy-resistant lung cancer](
Faye-Marie Vassel, Ke Bian, Graham C. Walker, and Michael T. Hemann
[Pheno-RNA, a method to associate genes with a specific phenotype, identifies genes linked to cellular transformation](
Rabih Darwiche and Kevin Struhl
[A missense variant in SLC39A8 confers risk for Crohn’s disease by disrupting manganese homeostasis and intestinal barrier integrity](
Toru Nakata, Elizabeth A. Creasey, Motohiko Kadoki, Helen Lin, Martin K. Selig, Junmei Yao, Ariel Lefkovith, Mark J. Daly, Daniel B. Graham, and Ramnik J. Xavier Immunology and Inflammation
[Complementary regulation of caspase-1 and IL-1β reveals additional mechanisms of dampened inflammation in bats](
Geraldine Goh, Matae Ahn, Feng Zhu, Lim Beng Lee, Dahai Luo, Aaron T. Irving, and Lin-Fa Wang
[A biomimetic five-module chimeric antigen receptor (5MCAR) designed to target and eliminate antigen-specific T cells](
Shio Kobayashi, Martin A. Thelin, Heather L. Parrish, Neha R. Deshpande, Mark S. Lee, Alborz Karimzadeh, Monika A. Niewczas, Thomas Serwold, and Michael S. Kuhns Medical Sciences
[CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response](
Daniele Biasci, Martin Smoragiewicz, Claire M. Connell, Zhikai Wang, Ya Gao, James E. D. Thaventhiran, Bristi Basu, Lukasz Magiera, T. Isaac Johnson, Lisa Bax, Aarthi Gopinathan, Christopher Isherwood, Ferdia A. Gallagher, Maria Pawula, Irena Hudecova, Davina Gale, Nitzan Rosenfeld, Petros Barmpounakis, Elizabeta Cristina Popa, Rebecca Brais, Edmund Godfrey, Fraz Mir, Frances M. Richards, Douglas T. Fearon, Tobias Janowitz, and Duncan I. Jodrell
[First-in-class humanized FSH blocking antibody targets bone and fat](
Sakshi Gera, Damini Sant, Shozeb Haider, Funda Korkmaz, Tan-Chun Kuo, Mehr Mathew, Helena Perez-Pena, Honglin Xie, Hao Chen, Rogerio Batista, Kejun Ma, Zhen Cheng, Elina Hadelia, Cemre Robinson, Anne Macdonald, Sari Miyashita, Anthony Williams, Gregory Jebian, Hirotaka Miyashita, Anisa Gumerova, Kseniia Ievleva, Pinar Smith, Jiahuan He, Vitaly Ryu, Victoria DeMambro, Matthew A. Quinn, Marcia Meseck, Se-Min Kim, T. Rajendra Kumar, Jameel Iqbal, Maria I. New, Daria Lizneva, Clifford J. Rosen, Aaron J. Hsueh, Tony Yuen, and Mone Zaidi
[Essential role of the linear ubiquitin chain assembly complex and TAK1 kinase in A20 mutant Hodgkin lymphoma](
Zhihui Song, Wei Wei, Wenming Xiao, Essel D. Al-Saleem, Reza Nejati, Liqi Chen, Jiejing Yin, Joseph Fabrizio, Michael N. Petrus, Thomas A. Waldmann, and Yibin Yang
[Antibody-mediated activation of the FGFR1/Klothoβ complex corrects metabolic dysfunction and alters food preference in obese humans](
Amos Baruch, Chin Wong, Leslie W. Chinn, Anjali Vaze, Junichiro Sonoda, Thomas Gelzleichter, Shan Chen, Nicholas Lewin-Koh, Linda Morrow, Suresh Dheerendra, Richard Boismenu, Johnny Gutierrez, Eric Wakshull, Maria E. Wilson, and Puneet S. Arora
[TAZ/Wnt-β-catenin/c-MYC axis regulates cystogenesis in polycystic kidney disease](
Eun Ji Lee, Eunjeong Seo, Jin Won Kim, Sun Ah Nam, Jong Young Lee, Jaehee Jun, Sumin Oh, Minah Park, Eek-hoon Jho, Kyung Hyun Yoo, Jong Hoon Park, and Yong Kyun Kim
[Systematic integrated analysis of genetic and epigenetic variation in diabetic kidney disease](
Xin Sheng, Chengxiang Qiu, Hongbo Liu, Caroline Gluck, Jesse Y. Hsu, Jiang He, Chi-yuan Hsu, Daohang Sha, Matthew R. Weir, Tamara Isakova, Dominic Raj, Hernan Rincon-Choles, Harold I. Feldman, Raymond Townsend, Hongzhe Li, and Katalin Susztak
[Curtailing FGF19’s mitogenicity by suppressing its receptor dimerization ability](
Jianlou Niu, Jing Zhao, Jiamin Wu, Guanting Qiao, Junlian Gu, Chuanren Zhou, Qi Li, Lei Ying, Dezhong Wang, Huan Lin, Xiaokun Li, Moosa Mohammadi, and Zhifeng Huang Microbiology
[The NF-ÎşB/leukemia inhibitory factor/STAT3 signaling pathway in antibody-mediated suppression of Sindbis virus replication in neurons](
Jane X. Yeh, Kimberly L. W. Schultz, Valerie Calvert, Emanuel F. Petricoin, and Diane E. Griffin
[Vibrio cholerae adapts to sessile and motile lifestyles by cyclic di-GMP regulation of cell shape](
Nicolas L. Fernandez, Brian Y. Hsueh, Nguyen T. Q. Nhu, Joshua L. Franklin, Yann S. Dufour, and Christopher M. Waters
[CEACAMs serve as toxin-stimulated receptors for enterotoxigenic Escherichia coli](
Alaullah Sheikh, Brunda Tumala, Tim J. Vickers, David Alvarado, Matthew A. Ciorba, Taufiqur Rahman Bhuiyan, Firdausi Qadri, Bernhard B. Singer, and James M. Fleckenstein
[The role of “spillover” in antibiotic resistance](
Scott W. Olesen, Marc Lipsitch, and Yonatan H. Grad Neuroscience
[Mechanical injuries of neurons induce tau mislocalization to dendritic spines and tau-dependent synaptic dysfunction](
Nicholas J. Braun, Katherine R. Yao, Patrick W. Alford, and Dezhi Liao
[Differential attentional control mechanisms by two distinct noradrenergic coeruleo-frontal cortical pathways](
Andrea Bari, Sangyu Xu, Michele Pignatelli, Daigo Takeuchi, Jiesi Feng, Yulong Li, and Susumu Tonegawa
[The structural basis for an on–off switch controlling Gβγ-mediated inhibition of TRPM3 channels](
Marc Behrendt, Fabian Gruss, Raissa Enzeroth, Sandeep Dembla, Siyuan Zhao, Pierre-Antoine Crassous, Florian Mohr, Mieke Nys, Nikolaos Louros, Rodrigo Gallardo, Valentina Zorzini, Doris Wagner, Anastassios Economou, Frederic Rousseau, Joost Schymkowitz, Stephan E. Philipp, Tibor Rohacs, Chris Ulens, and Johannes Oberwinkler
[Loss of TDP-43 in astrocytes leads to motor deficits by triggering A1-like reactive phenotype and triglial dysfunction](
Audrey Yi Tyan Peng, Ira Agrawal, Wan Yun Ho, Yi-Chun Yen, Ashley J. Pinter, Jerry Liu, Qi Xuan Cheryl Phua, Katrianne Bethia Koh, Jer-Cherng Chang, Emma Sanford, Jodie Hon Kiu Man, Peiyan Wong, David H. Gutmann, Greg Tucker-Kellogg, and Shuo-Chien Ling
[An evolutionarily acquired microRNA shapes development of mammalian cortical projections](
Jessica L. Diaz, Verl B. Siththanandan, Victoria Lu, Nicole Gonzalez-Nava, Lincoln Pasquina, Jessica L. MacDonald, Mollie B. Woodworth, Abdulkadir Ozkan, Ramesh Nair, Zihuai He, Vibhu Sahni, Peter Sarnow, Theo D. Palmer, Jeffrey D. Macklis, and Suzanne Tharin
[Neural control of rapid binocular eye movements: Saccade-vergence burst neurons](
Julie Quinet, Kevin Schultz, Paul J. May, and Paul D. Gamlin
[The inhibition of LSD1 via sequestration contributes to tau-mediated neurodegeneration](
Amanda K. Engstrom, Alicia C. Walker, Rohitha A. Moudgal, Dexter A. Myrick, Stephanie M. Kyle, Yu Bai, M. Jordan Rowley, and David J. Katz Pharmacology
[Advanced fluorescence microscopy reveals disruption of dynamic CXCR4 dimerization by subpocket-specific inverse agonists](
Ali Işbilir, Jan Möller, Marta Arimont, Vladimir Bobkov, Cristina Perpiñá-Viciano, Carsten Hoffmann, Asuka Inoue, Raimond Heukers, Chris de Graaf, Martine J. Smit, Paolo Annibale, and Martin J. Lohse Physiology
[LRRC8 family proteins within lysosomes regulate cellular osmoregulation and enhance cell survival to multiple physiological stresses](
Ping Li, Meiqin Hu, Ce Wang, Xinghua Feng, ZhuangZhuang Zhao, Ying Yang, Nirakar Sahoo, Mingxue Gu, Yexin Yang, Shiyu Xiao, Rajan Sah, Timothy L. Cover, Janet Chou, Raif Geha, Fernando Benavides, Richard I. Hume, and Haoxing Xu Plant Biology
[High-order mutants reveal an essential requirement for peroxidases but not laccases in Casparian strip lignification](
Nelson Rojas-Murcia, Kian Hématy, Yuree Lee, Aurélia Emonet, Robertas Ursache, Satoshi Fujita, Damien De Bellis, and Niko Geldner
[TREE1-EIN3–mediated transcriptional repression inhibits shoot growth in response to ethylene](
Likai Wang, Eun Esther Ko, Jaclyn Tran, and Hong Qiao Population Biology
[Nipah virus dynamics in bats and implications for spillover to humans](
Jonathan H. Epstein, Simon J. Anthony, Ariful Islam, A. Marm Kilpatrick, Shahneaz Ali Khan, Maria D. Balkey, Noam Ross, Ina Smith, Carlos Zambrana-Torrelio, Yun Tao, Ausraful Islam, Phenix Lan Quan, Kevin J. Olival, M. Salah Uddin Khan, Emily S. Gurley, M. Jahangir Hossein, Hume E. Field, Mark D. Fielder, Thomas Briese, Mahmudur Rahman, Christopher C. Broder, Gary Crameri, Lin-Fa Wang, Stephen P. Luby, W. Ian Lipkin, and Peter Daszak Psychological and Cognitive Sciences
[Voluntary restrictions on self-reliance increase cooperation and mitigate wealth inequality](
Jörg Gross and Robert Böhm
[Self-organization of cortical areas in the development and evolution of neocortex](
Nabil Imam and Barbara L. Finlay
[Adversarial vulnerabilities of human decision-making](
Amir Dezfouli, Richard Nock, and Peter Dayan
[Echolocating bats accumulate information from acoustic snapshots to predict auditory object motion](
Angeles Salles, Clarice Anna Diebold, and Cynthia F. Moss --------------------------------------------------------------- Corrections
[Correction for Meng et al., Noncovalent π-stacked robust topological organic framework]( [Correction for Stein et al., Timing and magnitude of Southern Ocean sea ice/carbon cycle feedbacks]( [Correction for Monson et al., Neutral evolution of human enamel–dentine junction morphology]( [Correction for le Roux et al., Animal body size distribution influences the ratios of nutrients supplied to plants]( [Cover] --------------------------------------------------------------- This message was sent to {EMAIL}. [Unsubscribe]( from or [edit]( your subscription for this service.
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