[PNAS]
[Coronavirus eTOC](/cgi/adclick/?ad=55236&adclick=true&url=https%3A%2F%2Fwww.pnas.org%2Fcoronavirus%3Futm_source%3DEmail%26utm_medium%3Demail%26utm_campaign%3DCOVID-19%26utm_content%3Detocbannerads)
[September 29, 2020; Vol. 117, No. 39](
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This Week in PNAS
[In This Issue](
This week's research highlights
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QnAs
[QnAs with Janet Currie](
Tinsley H. Davis
Interviews with leading scientific researchers and newsmakers
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Profile
[Profile of Cynthia Friend](
Farooq Ahmed
The life and work of NAS members
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Commentaries
[The immune signatures of multiple sclerosis: Lessons from twin studies](
Pablo Villoslada and Scott S. Zamvil
[Predators and rainfall control spatial biogeochemistry in a landscape of fear](
Oswald J. Schmitz
[Expanding the horizons of genome editing in the fruit fly with Cas12a](
Ben Ewen-Campen and Norbert Perrimon
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Perspective
[Opportunities and limitations of genetically modified nonhuman primate models for neuroscience research](
Guoping Feng, Frances E. Jensen, Henry T. Greely, Hideyuki Okano, Stefan Treue, Angela C. Roberts, James G. Fox, Sarah Caddick, Mu-ming Poo, William T. Newsome, and John H. Morrison
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Letters
[Using the curriculum vitae to promote gender equity during the COVID-19 pandemic](
Vineet M. Arora, Charles M. Wray, Avital Y. O’Glasser, Mark Shapiro, and Shikha Jain
[Reply to Arora et al.: Concerns and considerations about using the CV as an equity tool](
Jessica L. Malisch, Breanna N. Harris, Shanen M. Sherrer, Kristy A. Lewis, Stephanie L. Shepherd, Pumtiwitt C. McCarthy, Jessica L. Spott, Elizabeth P. Karam, Naima Moustaid-Moussa, Jessica McCrory Calarco, Latha Ramalingam, Amelia E. Talley, Jaclyn E. Cañas-Carrell, Karin Ardon-Dryer, Dana A. Weiser, Ximena E. Bernal, and Jennifer Deitloff
[Genetic variant rs7820258 regulates the expression of indoleamine 2,3-dioxygenase 1 in brain regions](
Zhijie Han, Dian He, and Yang Zhang
[Reply to Han et al.: On track for an IDO1-based personalized therapy in autoimmunity](
Giada Mondanelli, Agostinho Carvalho, Paolo Puccetti, Ursula Grohmann, and Claudia Volpi
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Brief Report
[Early preference for face-like stimuli in solitary species as revealed by tortoise hatchlings](
Elisabetta Versace, Silvia Damini, and Gionata Stancher
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Physical Sciences
Applied Physical Sciences
[Near-zero-index media as electromagnetic ideal fluids](
Iñigo Liberal, Michaël Lobet, Yue Li, and Nader Engheta
[Shear-assisted grain coarsening in colloidal polycrystals](
Wei Li, Yi Peng, Yongjun Zhang, Tim Still, A. G. Yodh, and Yilong Han
[Functional advantages of Lévy walks emerging near a critical point](
Masato S. Abe
Biophysics and Computational Biology
[Interfacial plasticity facilitates high reaction rate of E. coli FAS malonyl-CoA:ACP transacylase, FabD](
Laetitia E. Misson, Jeffrey T. Mindrebo, Tony D. Davis, Ashay Patel, J. Andrew McCammon, Joseph P. Noel, and Michael D. Burkart
Chemistry
[Exploring the landscape of model representations](
Thomas T. Foley, Katherine M. Kidder, M. Scott Shell, and W. G. Noid
[Visualizing conical intersection passages via vibronic coherence maps generated by stimulated ultrafast X-ray Raman signals](
Daniel Keefer, Thomas Schnappinger, Regina de Vivie-Riedle, and Shaul Mukamel
[Polyamorphism of vapor-deposited amorphous selenium in response to light](
Aixi Zhang, Yi Jin, Tianyi Liu, Richard B. Stephens, and Zahra Fakhraai
[Thermodynamic and kinetic design principles for amyloid-aggregation inhibitors](
Thomas C. T. Michaels, Andela Šarić, Georg Meisl, Gabriella T. Heller, Samo Curk, Paolo Arosio, Sara Linse, Christopher M. Dobson, Michele Vendruscolo, and Tuomas P. J. Knowles
Earth, Atmospheric, and Planetary Sciences
[Modeling the stability of polygonal patterns of vortices at the poles of Jupiter as revealed by the Juno spacecraft](
Cheng Li, Andrew P. Ingersoll, Alexandra P. Klipfel, and Harriet Brettle
[The seawater carbon inventory at the Paleocene–Eocene Thermal Maximum](
Laura L. Haynes and Bärbel Hönisch
Engineering
[Untethered control of functional origami microrobots with distributed actuation](
Larissa S. Novelino, Qiji Ze, Shuai Wu, Glaucio H. Paulino, and Ruike Zhao
[Engineered biomimetic nanoparticle for dual targeting of the cancer stem-like cell population in sonic hedgehog medulloblastoma](
Jinhwan Kim, Abhinav Dey, Anshu Malhotra, Jingbo Liu, Song Ih Ahn, Yoshitaka J. Sei, Anna M. Kenney, Tobey J. MacDonald, and YongTae Kim
Physics
[Geodesic fibrations for packing diabolic domains](
Randall D. Kamien and Thomas Machon
[Emergence of anomalous dynamics in soft matter probed at the European XFEL](
Felix Lehmkühler, Francesco Dallari, Avni Jain, Marcin Sikorski, Johannes Möller, Lara Frenzel, Irina Lokteva, Grant Mills, Michael Walther, Harald Sinn, Florian Schulz, Michael Dartsch, Verena Markmann, Richard Bean, Yoonhee Kim, Patrik Vagovic, Anders Madsen, Adrian P. Mancuso, and Gerhard Grübel
Statistics
[Causal inference in genetic trio studies](
Stephen Bates, Matteo Sesia, Chiara Sabatti, and Emmanuel Candès
[National population mapping from sparse survey data: A hierarchical Bayesian modeling framework to account for uncertainty](
Douglas R. Leasure, Warren C. Jochem, Eric M. Weber, Vincent Seaman, and Andrew J. Tatem
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Social Sciences
Anthropology
[El Niño resilience farming on the north coast of Peru](
Ari Caramanica, Luis Huaman Mesia, Claudia R. Morales, Gary Huckleberry, Luis Jaime Castillo B., and Jeffrey Quilter
Economic Sciences
[Treatment of mental illness in American adolescents varies widely within and across areas](
Emily Cuddy and Janet Currie
Environmental Sciences
[Holocene coastal evolution preceded the expansion of paddy field rice farming](
Ting Ma, Barry V. Rolett, Zhuo Zheng, and Yongqiang Zong
[Synchrony matters more than species richness in plant community stability at a global scale](
Enrique Valencia, Francesco de Bello, Thomas Galland, Peter B. Adler, Jan Lepš, Anna E-Vojtkó, Roel van Klink, Carlos P. Carmona, Jiří Danihelka, Jürgen Dengler, David J. Eldridge, Marc Estiarte, Ricardo García-González, Eric Garnier, Daniel Gómez‐García, Susan P. Harrison, Tomáš Herben, Ricardo Ibáñez, Anke Jentsch, Norbert Juergens, Miklós Kertész, Katja Klumpp, Frédérique Louault, Rob H. Marrs, Romà Ogaya, Gábor Ónodi, Robin J. Pakeman, Iker Pardo, Meelis Pärtel, Begoña Peco, Josep Peñuelas, Richard F. Pywell, Marta Rueda, Wolfgang Schmidt, Ute Schmiedel, Martin Schuetz, Hana Skálová, Petr Šmilauer, Marie Šmilauerová, Christian Smit, MingHua Song, Martin Stock, James Val, Vigdis Vandvik, David Ward, Karsten Wesche, Susan K. Wiser, Ben A. Woodcock, Truman P. Young, Fei- Hai Yu, Martin Zobel, and Lars Götzenberger
Political Sciences
[Political partisanship influences behavioral responses to governors’ recommendations for COVID-19 prevention in the United States](
Guy Grossman, Soojong Kim, Jonah M. Rexer, and Harsha Thirumurthy
Psychological and Cognitive Sciences
[Open science, communal culture, and women’s participation in the movement to improve science](
Mary C. Murphy, Amanda F. Mejia, Jorge Mejia, Xiaoran Yan, Sapna Cheryan, Nilanjana Dasgupta, Mesmin Destin, Stephanie A. Fryberg, Julie A. Garcia, Elizabeth L. Haines, Judith M. Harackiewicz, Alison Ledgerwood, Corinne A. Moss-Racusin, Lora E. Park, Sylvia P. Perry, Kate A. Ratliff, Aneeta Rattan, Diana T. Sanchez, Krishna Savani, Denise Sekaquaptewa, Jessi L. Smith, Valerie Jones Taylor, Dustin B. Thoman, Daryl A. Wout, Patricia L. Mabry, Susanne Ressl, Amanda B. Diekman, and Franco Pestilli
[Hierarchical structure is employed by humans during visual motion perception](
Johannes Bill, Hrag Pailian, Samuel J. Gershman, and Jan Drugowitsch
Social Sciences
[Fifty years of capacity building in the search for new marine natural products](
Miguel C. Leal, Jaime M. Anaya-Rojas, Murray H. G. Munro, John W. Blunt, Carlos J. Melian, Ricardo Calado, and Moritz D. Lürig
[National population mapping from sparse survey data: A hierarchical Bayesian modeling framework to account for uncertainty](
Douglas R. Leasure, Warren C. Jochem, Eric M. Weber, Vincent Seaman, and Andrew J. Tatem
[Spatial heterogeneity can lead to substantial local variations in COVID-19 timing and severity](
Loring J. Thomas, Peng Huang, Fan Yin, Xiaoshuang Iris Luo, Zack W. Almquist, John R. Hipp, and Carter T. Butts
Sustainability Science
[Overstated carbon emission reductions from voluntary REDD+ projects in the Brazilian Amazon](
Thales A. P. West, Jan Börner, Erin O. Sills, and Andreas Kontoleon
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Biological Sciences
Agricultural Sciences
[Donor-derived spermatogenesis following stem cell transplantation in sterile NANOS2 knockout males](
Michela Ciccarelli, Mariana I. Giassetti, Deqiang Miao, Melissa J. Oatley, Colton Robbins, Blanca Lopez-Biladeau, Muhammad Salman Waqas, Ahmed Tibary, Bruce Whitelaw, Simon Lillico, Chi-Hun Park, Ki-Eun Park, Bhanu Telugu, Zhiqiang Fan, Ying Liu, Misha Regouski, Irina A. Polejaeva, and Jon M. Oatley
Applied Biological Sciences
[Engineered biomimetic nanoparticle for dual targeting of the cancer stem-like cell population in sonic hedgehog medulloblastoma](
Jinhwan Kim, Abhinav Dey, Anshu Malhotra, Jingbo Liu, Song Ih Ahn, Yoshitaka J. Sei, Anna M. Kenney, Tobey J. MacDonald, and YongTae Kim
[Extracellular microRNAs in human circulation are associated with miRISC complexes that are accessible to anti-AGO2 antibody and can bind target mimic oligonucleotides](
Hirosha Geekiyanage, Shima Rayatpisheh, James A. Wohlschlegel, Robert Brown Jr, and Victor Ambros
Biochemistry
[Interfacial plasticity facilitates high reaction rate of E. coli FAS malonyl-CoA:ACP transacylase, FabD](
Laetitia E. Misson, Jeffrey T. Mindrebo, Tony D. Davis, Ashay Patel, J. Andrew McCammon, Joseph P. Noel, and Michael D. Burkart
[Ribulose 1,5-bisphosphate carboxylase/oxygenase activates O2 by electron transfer](
Camille Bathellier, Li-Juan Yu, Graham D. Farquhar, Michelle L. Coote, George H. Lorimer, and Guillaume Tcherkez
[Victorin, the host-selective cyclic peptide toxin from the oat pathogen Cochliobolus victoriae, is ribosomally encoded](
Simon C. Kessler, Xianghui Zhang, Megan C. McDonald, Cameron L. M. Gilchrist, Zeran Lin, Adriana Rightmyer, Peter S. Solomon, B. Gillian Turgeon, and Yit-Heng Chooi
Biophysics and Computational Biology
[Exploring the landscape of model representations](
Thomas T. Foley, Katherine M. Kidder, M. Scott Shell, and W. G. Noid
[Thermodynamic and kinetic design principles for amyloid-aggregation inhibitors](
Thomas C. T. Michaels, Andela Šarić, Georg Meisl, Gabriella T. Heller, Samo Curk, Paolo Arosio, Sara Linse, Christopher M. Dobson, Michele Vendruscolo, and Tuomas P. J. Knowles
[Uncovering a membrane-distal conformation of KRAS available to recruit RAF to the plasma membrane](
Que N. Van, Cesar A. López, Marco Tonelli, Troy Taylor, Ben Niu, Christopher B. Stanley, Debsindhu Bhowmik, Timothy H. Tran, Peter H. Frank, Simon Messing, Patrick Alexander, Daniel Scott, Xiaoying Ye, Matt Drew, Oleg Chertov, Mathias Lösche, Arvind Ramanathan, Michael L. Gross, Nicolas W. Hengartner, William M. Westler, John L. Markley, Dhirendra K. Simanshu, Dwight V. Nissley, William K. Gillette, Dominic Esposito, Frank McCormick, S. Gnanakaran, Frank Heinrich, and Andrew G. Stephen
[General and robust covalently linked graphene oxide affinity grids for high-resolution cryo-EM](
Feng Wang, Yanxin Liu, Zanlin Yu, Sam Li, Shengjie Feng, Yifan Cheng, and David A. Agard
[Proline-rich domain of human ALIX contains multiple TSG101-UEV interaction sites and forms phosphorylation-mediated reversible amyloids](
Ruben D. Elias, Wen Ma, Rodolfo Ghirlando, Charles D. Schwieters, Vijay S. Reddy, and Lalit Deshmukh
[Disruption of a key ligand-H-bond network drives dissociative properties in vamorolone for Duchenne muscular dystrophy treatment](
Xu Liu, Yashuo Wang, Jennifer S. Gutierrez, Jesse M. Damsker, Kanneboyina Nagaraju, Eric P. Hoffman, and Eric A. Ortlund
[Supertertiary protein structure affects an allosteric network](
Louise Laursen, Johanna Kliche, Stefano Gianni, and Per Jemth
[Tuning the Baird aromatic triplet-state energy of cyclooctatetraene to maximize the self-healing mechanism in organic fluorophores](
Avik K. Pati, Ouissam El Bakouri, Steffen Jockusch, Zhou Zhou, Roger B. Altman, Gabriel A. Fitzgerald, Wesley B. Asher, Daniel S. Terry, Alessandro Borgia, Michael D. Holsey, Jake E. Batchelder, Chathura Abeywickrama, Brandt Huddle, Dominic Rufa, Jonathan A. Javitch, Henrik Ottosson, and Scott C. Blanchard
Cell Biology
[Hemostasis vs. homeostasis: Platelets are essential for preserving vascular barrier function in the absence of injury or inflammation](
Shuchi Gupta, Christoph Konradt, Adam Corken, Jerry Ware, Bernhard Nieswandt, Jorge Di Paola, Mei Yu, Demin Wang, Marvin T. Nieman, Sidney W. Whiteheart, and Lawrence F. Brass
[Kindlin-3 loss curbs chronic myeloid leukemia in mice by mobilizing leukemic stem cells from protective bone marrow niches](
Peter William Krenn, Steffen Koschmieder, and Reinhard Fässler
Ecology
[Functional advantages of Lévy walks emerging near a critical point](
Masato S. Abe
[Synchrony matters more than species richness in plant community stability at a global scale](
Enrique Valencia, Francesco de Bello, Thomas Galland, Peter B. Adler, Jan Lepš, Anna E-Vojtkó, Roel van Klink, Carlos P. Carmona, Jiří Danihelka, Jürgen Dengler, David J. Eldridge, Marc Estiarte, Ricardo García-González, Eric Garnier, Daniel Gómez‐García, Susan P. Harrison, Tomáš Herben, Ricardo Ibáñez, Anke Jentsch, Norbert Juergens, Miklós Kertész, Katja Klumpp, Frédérique Louault, Rob H. Marrs, Romà Ogaya, Gábor Ónodi, Robin J. Pakeman, Iker Pardo, Meelis Pärtel, Begoña Peco, Josep Peñuelas, Richard F. Pywell, Marta Rueda, Wolfgang Schmidt, Ute Schmiedel, Martin Schuetz, Hana Skálová, Petr Šmilauer, Marie Šmilauerová, Christian Smit, MingHua Song, Martin Stock, James Val, Vigdis Vandvik, David Ward, Karsten Wesche, Susan K. Wiser, Ben A. Woodcock, Truman P. Young, Fei- Hai Yu, Martin Zobel, and Lars Götzenberger
Environmental Sciences
[Holocene coastal evolution preceded the expansion of paddy field rice farming](
Ting Ma, Barry V. Rolett, Zhuo Zheng, and Yongqiang Zong
[Late lactation in small mammals is a critically sensitive window of vulnerability to elevated ambient temperature](
Zhi-Jun Zhao, Catherine Hambly, Lu-Lu Shi, Zhong-Qiang Bi, Jing Cao, and John R. Speakman
Evolution
[Reconstruction of the birth of a male sex chromosome present in Atlantic herring](
Nima Rafati, Junfeng Chen, Amaury Herpin, Mats E. Pettersson, Fan Han, Chungang Feng, Ola Wallerman, Carl-Johan Rubin, Sandrine Péron, Arianna Cocco, Mårten Larsson, Christian Trötschel, Ansgar Poetsch, Kai Korsching, Wolfgang Bönigk, Heinz G. Körschen, Florian Berg, Arild Folkvord, U. Benjamin Kaupp, Manfred Schartl, and Leif Andersson
Genetics
[Causal inference in genetic trio studies](
Stephen Bates, Matteo Sesia, Chiara Sabatti, and Emmanuel Candès
[New Guinea highland wild dogs are the original New Guinea singing dogs](
Suriani Surbakti, Heidi G. Parker, James K. McIntyre, Hendra K. Maury, Kylie M. Cairns, Meagan Selvig, Margaretha Pangau-Adam, Apolo Safonpo, Leonardo Numberi, Dirk Y. P. Runtuboi, Brian W. Davis, and Elaine A. Ostrander
[A CRISPR homing gene drive targeting a haplolethal gene removes resistance alleles and successfully spreads through a cage population](
Jackson Champer, Emily Yang, Esther Lee, Jingxian Liu, Andrew G. Clark, and Philipp W. Messer
Immunology and Inflammation
[Suboptimal SARS-CoV-2−specific CD8+ T cell response associated with the prominent HLA-A*02:01 phenotype](
Jennifer R. Habel, Thi H. O. Nguyen, Carolien E. van de Sandt, Jennifer A. Juno, Priyanka Chaurasia, Kathleen Wragg, Marios Koutsakos, Luca Hensen, Xiaoxiao Jia, Brendon Chua, Wuji Zhang, Hyon-Xhi Tan, Katie L. Flanagan, Denise L. Doolan, Joseph Torresi, Weisan Chen, Linda M. Wakim, Allen C. Cheng, Peter C. Doherty, Jan Petersen, Jamie Rossjohn, Adam K. Wheatley, Stephen J. Kent, Louise C. Rowntree, and Katherine Kedzierska
[Early programming of CD8+ T cell response by the orphan nuclear receptor NR4A3](
Livia Odagiu, Salix Boulet, Dave Maurice De Sousa, Jean-François Daudelin, Sandrine Nicolas, and Nathalie Labrecque
[ORAI1 and ORAI2 modulate murine neutrophil calcium signaling, cellular activation, and host defense](
Derayvia Grimes, Ryan Johnson, Madeline Pashos, Celeste Cummings, Chen Kang, Georgia R. Sampedro, Eric Tycksen, Helen J. McBride, Rajan Sah, Clifford A. Lowell, and Regina A. Clemens
Medical Sciences
[Tumor regression and resistance mechanisms upon CDK4 and RAF1 inactivation in KRAS/P53 mutant lung adenocarcinomas](
Laura Esteban-Burgos, Haiyun Wang, Patricia Nieto, Jie Zheng, Carmen Blanco-Aparicio, Carmen Varela, Gonzalo Gómez-López, Fernando Fernández-García, Manuel Sanclemente, Carmen Guerra, Matthias Drosten, Javier Galán, Eduardo Caleiras, Jorge Martínez-Torrecuadrada, Lluis Fajas, Sheng-Bin Peng, David Santamaría, Monica Musteanu, and Mariano Barbacid
[PIK3CA C-terminal frameshift mutations are novel oncogenic events that sensitize tumors to PI3K-α inhibition](
Jennifer M. Spangle, Thanh Von, Dean C. Pavlick, Arina Khotimsky, Jean J. Zhao, and Thomas M. Roberts
[Regulation of hepatic insulin signaling and glucose homeostasis by sphingosine kinase 2](
Gulibositan Aji, Yu Huang, Mei Li Ng, Wei Wang, Tian Lan, Min Li, Yufei Li, Qi Chen, Rui Li, Sishan Yan, Collin Tran, James G. Burchfield, Timothy A. Couttas, Jinbiao Chen, Long Hoa Chung, Da Liu, Carol Wadham, Philip J. Hogg, Xin Gao, Mathew A. Vadas, Jennifer R. Gamble, Anthony S. Don, Pu Xia, and Yanfei Qi
Microbiology
[Short Vi-polysaccharide abrogates T-independent immune response and hyporesponsiveness elicited by long Vi-CRM197 conjugate vaccine](
Francesca Micoli, Stefania P. Bjarnarson, Melissa Arcuri, Audur Anna Aradottir Pind, Gudbjorg J. Magnusdottir, Francesca Necchi, Roberta Di Benedetto, Martina Carducci, Fabiola Schiavo, Carlo Giannelli, Ivan Pisoni, Laura B. Martin, Giuseppe Del Giudice, Calman A. MacLennan, Rino Rappuoli, Ingileif Jonsdottir, and Allan Saul
[SARS-CoV-2 detection using isothermal amplification and a rapid, inexpensive protocol for sample inactivation and purification](
Brian A. Rabe and Constance Cepko
[Multiheme hydroxylamine oxidoreductases produce NO during ammonia oxidation in methanotrophs](
Wouter Versantvoort, Arjan Pol, Mike S. M. Jetten, Laura van Niftrik, Joachim Reimann, Boran Kartal, and Huub J. M. Op den Camp
[Microglia depletion exacerbates demyelination and impairs remyelination in a neurotropic coronavirus infection](
Alan Sariol, Samantha Mackin, Merri-Grace Allred, Chen Ma, Yu Zhou, Qinran Zhang, Xiufen Zou, Juan E. Abrahante, David K. Meyerholz, and Stanley Perlman
[Modulation of acyl-carnitines, the broad mechanism behind Wolbachia-mediated inhibition of medically important flaviviruses in Aedes aegypti](
Gayathri Manokaran, Heather A. Flores, Conor T. Dickson, Vinod K. Narayana, Komal Kanojia, Saravanan Dayalan, Dedreia Tull, Malcolm J. McConville, Jason M. Mackenzie, and Cameron P. Simmons
[Nanaerobic growth enables direct visualization of dynamic cellular processes in human gut symbionts](
Leonor García-Bayona, Michael J. Coyne, Noam Hantman, Paula Montero-Llopis, Salena S. Von, Takeshi Ito, Michael H. Malamy, Marek Basler, Blanca Barquera, and Laurie E. Comstock
[Structure–function studies of Rgg binding to pheromones and target promoters reveal a model of transcription factor interplay](
Glenn C. Capodagli, Kaitlyn M. Tylor, Jason T. Kaelber, Vasileios I. Petrou, Michael J. Federle, and Matthew B. Neiditch
Neuroscience
[Netrin1 deficiency activates MST1 via UNC5B receptor, promoting dopaminergic apoptosis in Parkinson’s disease](
Eun Hee Ahn, Seong Su Kang, Qi Qi, Xia Liu, and Keqiang Ye
[Homeostatic mechanisms regulate distinct aspects of cortical circuit dynamics](
Yue Kris Wu, Keith B. Hengen, Gina G. Turrigiano, and Julijana Gjorgjieva
[Distance-dependent regulation of NMDAR nanoscale organization along hippocampal neuron dendrites](
Joana S. Ferreira, Julien P. Dupuis, Blanka Kellermayer, Nathan Bénac, Constance Manso, Delphine Bouchet, Florian Levet, Corey Butler, Jean-Baptiste Sibarita, and Laurent Groc
[Hair cell α9α10 nicotinic acetylcholine receptor functional expression regulated by ligand binding and deafness gene products](
Shenyan Gu, Daniel Knowland, Jose A. Matta, Min L. O’Carroll, Weston B. Davini, Madhurima Dhara, Hae-Jin Kweon, and David S. Bredt
Pharmacology
[Fifty years of capacity building in the search for new marine natural products](
Miguel C. Leal, Jaime M. Anaya-Rojas, Murray H. G. Munro, John W. Blunt, Carlos J. Melian, Ricardo Calado, and Moritz D. Lürig
Physiology
[Regulation of titin-based cardiac stiffness by unfolded domain oxidation (UnDOx)](
Christine M. Loescher, Martin Breitkreuz, Yong Li, Alexander Nickel, Andreas Unger, Alexander Dietl, Andreas Schmidt, Belal A. Mohamed, Sebastian Kötter, Joachim P. Schmitt, Marcus Krüger, Martina Krüger, Karl Toischer, Christoph Maack, Lars I. Leichert, Nazha Hamdani, and Wolfgang A. Linke
Plant Biology
[Architecture of DNA elements mediating ARF transcription factor binding and auxin-responsive gene expression in Arabidopsis](
Alejandra Freire-Rios, Keita Tanaka, Isidro Crespo, Elmar van der Wijk, Yana Sizentsova, Victor Levitsky, Simon Lindhoud, Mattia Fontana, Johannes Hohlbein, D. Roeland Boer, Victoria Mironova, and Dolf Weijers
Population Biology
[Estimation of Rift Valley fever virus spillover to humans during the Mayotte 2018–2019 epidemic](
Raphaëlle Métras, W. John Edmunds, Chouanibou Youssouffi, Laure Dommergues, Guillaume Fournié, Anton Camacho, Sebastian Funk, Eric Cardinale, Gilles Le Godais, Soihibou Combo, Laurent Filleul, Hassani Youssouf, and Marion Subiros
[Local lockdowns outperform global lockdown on the far side of the COVID-19 epidemic curve](
Vadim A. Karatayev, Madhur Anand, and Chris T. Bauch
Psychological and Cognitive Sciences
[Hierarchical structure is employed by humans during visual motion perception](
Johannes Bill, Hrag Pailian, Samuel J. Gershman, and Jan Drugowitsch
[Goal-directed and stimulus-driven selection of internal representations](
Freek van Ede, Alexander G. Board, and Anna C. Nobre
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Corrections
[Correction for Reitz et al., Genomic analysis of siderophore β-hydroxylases reveals divergent stereocontrol and expands the condensation domain family](
[Correction for Liu et al., β-Arrestin2 is a critical component of the GPCR–eNOS signalosome](
[Correction for Hirose et al., Acrosin is essential for sperm penetration through the zona pellucida in hamsters](
[Correction for Xiang et al., Using synthetic biology to overcome barriers to stable expression of nitrogenase in eukaryotic organelles](
[Cover]
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