[PNAS]
[PNAS-Highlights-eTOC](/cgi/adclick/?ad=55172&adclick=true&url=https%3A%2F%2Fpnas.us15.list-manage.com%2Fsubscribe%2Fpost%3Fu%3D371d96023d24fb109b778621f%26id%3Db053c2ccce%26SIGNUP%3Dfmportal)
[September 1, 2020; Vol. 117, No. 35](
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This Week in PNAS
[In This Issue](
This week's research highlights
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Opinion
[Opinion: Science policy for scientists: A simple task for great effect](
William Gaieck, J.P. Lawrence, Maria Montchal, William Pandori, and Evelyn Valdez-Ward
Leading scientists discuss current issues
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Science and Culture
[Science and Culture: Universities move science labs to the kitchen](
Carolyn Beans
How science intersects with culture
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QnAs
[QnAs with Sharad Goel and Allison Koenecke](
Sandeep Ravindran
Interviews with leading scientific researchers and newsmakers
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Profile
[Profile of Edward H. Egelman](
Sandeep Ravindran
The life and work of NAS members
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Commentaries
[A panorama of transcription-coupled repair in yeast chromatin](
Dong Wang
[An endosymbiont’s journey through metamorphosis of its insect host](
Martin Kaltenpoth
[Ediacaran sponges, animal biomineralization, and skeletal reefs](
Shuhai Xiao
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Letters
[Are nitrogen-to-phosphorus ratios of Chinese lakes actually increasing?](
Boqiang Qin, Yunlin Zhang, Guangwei Zhu, Zhijun Gong, Jianming Deng, David P. Hamilton, Guang Gao, Kun Shi, Jian Zhou, Keqiang Shao, Mengyuan Zhu, Yongqiang Zhou, Xiangming Tang, and Liang Li
[Reply to Qin et al.: Consistency of monitoring data is key to explain the long-term nationwide trend of nutrients in lakes](
Yan Lin, Xin Dong, Mengzhu Wang, and Yindong Tong
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Brief Reports
[Extended dilation of the radiocarbon time scale between 40,000 and 48,000 y BP and the overlap between Neanderthals and Homo sapiens](
Edouard Bard, Timothy J. Heaton, Sahra Talamo, Bernd Kromer, Ron W. Reimer, and Paula J. Reimer
[Supernova triggers for end-Devonian extinctions](
Brian D. Fields, Adrian L. Melott, John Ellis, Adrienne F. Ertel, Brian J. Fry, Bruce S. Lieberman, Zhenghai Liu, Jesse A. Miller, and Brian C. Thomas
[Overweight, obesity, and risk of hospitalization for COVID-19: A community-based cohort study of adults in the United Kingdom](
Mark Hamer, Catharine R. Gale, Mika Kivimäki, and G. David Batty
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Physical Sciences
Applied Physical Sciences
[A β-barrel for oil transport through lipid membranes: Dynamic NMR structures of AlkL](
Tobias Schubeis, Tanguy Le Marchand, Csaba Daday, Wojciech Kopec, Kumar Tekwani Movellan, Jan Stanek, Tom S. Schwarzer, Kathrin Castiglione, Bert L. de Groot, Guido Pintacuda, and Loren B. Andreas
[Massively parallel classical logic via coherent dynamics of an ensemble of quantum systems with dispersion in size](
Hugo Gattuso, R. D. Levine, and F. Remacle
Astronomy
[Quantifying the information impact of future searches for exoplanetary biosignatures](
Amedeo Balbi and Claudio Grimaldi
Biophysics and Computational Biology
[Compression stiffening of fibrous networks with stiff inclusions](
Jordan L. Shivers, Jingchen Feng, Anne S. G. van Oosten, Herbert Levine, Paul A. Janmey, and Fred C. MacKintosh
[Single-molecule diffusometry reveals no catalysis-induced diffusion enhancement of alkaline phosphatase as proposed by FCS experiments](
Zhijie Chen, Alan Shaw, Hugh Wilson, Maxime Woringer, Xavier Darzacq, Susan Marqusee, Quan Wang, and Carlos Bustamante
[The αβTCR mechanosensor exploits dynamic ectodomain allostery to optimize its ligand recognition site](
Wonmuk Hwang, Robert J. Mallis, Matthew J. Lang, and Ellis L. Reinherz
[Talin folding as the tuning fork of cellular mechanotransduction](
Rafael Tapia-Rojo, Álvaro Alonso-Caballero, and Julio M. Fernández
Chemistry
[Universal free-energy landscape produces efficient and reversible electron bifurcation](
J. L. Yuly, P. Zhang, C. E. Lubner, J. W. Peters, and D. N. Beratan
[Device-quality, reconfigurable metamaterials from shape-directed nanocrystal assembly](
Wenjie Zhou, Zizhuo Liu, Ziyin Huang, Haixin Lin, Devleena Samanta, Qing-Yuan Lin, Koray Aydin, and Chad A. Mirkin
[HARC as an open-shell strategy to bypass oxidative addition in Ullmann–Goldberg couplings](
Marissa N. Lavagnino, Tao Liang, and David W. C. MacMillan
[Origin of the “odd” behavior in the ultraviolet photochemistry of ozone](
Shanyu Han, Carolyn E. Gunthardt, Richard Dawes, Daiqian Xie, Simon W. North, and Hua Guo
[Self-template–assisted micro-phase segregation in blended liquid-crystalline block copolymers films toward three-dimensional structures](
Yusuke Hibi, Yuki Oguchi, Yuta Shimizu, Kayoko Hashimoto, Katsuya Kondo, and Tomokazu Iyoda
Earth, Atmospheric, and Planetary Sciences
[Siberian and temperate ecosystems shape Northern Hemisphere atmospheric CO2 seasonal amplification](
Xin Lin, Brendan M. Rogers, Colm Sweeney, Frédéric Chevallier, Mikhail Arshinov, Edward Dlugokencky, Toshinobu Machida, Motoki Sasakawa, Pieter Tans, and Gretchen Keppel-Aleks
[Evidence for complex iron oxides in the deep mantle from FeNi(Cu) inclusions in superdeep diamond](
Chiara Anzolini, Katharina Marquardt, Vincenzo Stagno, Luca Bindi, Daniel J. Frost, D. Graham Pearson, Jeffrey W. Harris, Russell J. Hemley, and Fabrizio Nestola
[Illuminating the physics of dynamic friction through laboratory earthquakes on thrust faults](
Yuval Tal, Vito Rubino, Ares J. Rosakis, and Nadia Lapusta
[Constraining crustal silica on ancient Earth](
C. Brenhin Keller and T. Mark Harrison
[The motley drivers of heat and cold exposure in 21st century US cities](
Ashley Mark Broadbent, Eric Scott Krayenhoff, and Matei Georgescu
[Volcanic controls on seawater sulfate over the past 120 million years](
Thomas A. Laakso, Anna Waldeck, Francis A. Macdonald, and David Johnston
[Significant Zr isotope variations in single zircon grains recording magma evolution history](
Jing-Liang Guo, Zaicong Wang, Wen Zhang, Frédéric Moynier, Dandan Cui, Zhaochu Hu, and Mihai N. Ducea
[Dry soils can intensify mesoscale convective systems](
Cornelia Klein and Christopher M. Taylor
Engineering
[Ultraflexible organic light-emitting diodes for optogenetic nerve stimulation](
Dongmin Kim, Tomoyuki Yokota, Toshiki Suzuki, Sunghoon Lee, Taeseong Woo, Wakako Yukita, Mari Koizumi, Yutaro Tachibana, Hiromu Yawo, Hiroshi Onodera, Masaki Sekino, and Takao Someya
[Color-neutral, semitransparent organic photovoltaics for power window applications](
Yongxi Li, Xia Guo, Zhengxing Peng, Boning Qu, Hongping Yan, Harald Ade, Maojie Zhang, and Stephen R. Forrest
[Bicontinuous phase separation of lithium-ion battery electrodes for ultrahigh areal loading](
Jung Tae Lee, Changshin Jo, and Michael De Volder
[Membrane-assisted radiant cooling for expanding thermal comfort zones globally without air conditioning](
Eric Teitelbaum, Kian Wee Chen, Dorit Aviv, Kipp Bradford, Lea Ruefenacht, Denon Sheppard, Megan Teitelbaum, Forrest Meggers, Jovan Pantelic, and Adam Rysanek
[Nuclear mechanosensing controls MSC osteogenic potential through HDAC epigenetic remodeling](
Anouk R. Killaars, Cierra J. Walker, and Kristi S. Anseth
[Efficient and nontoxic biomolecule delivery to primary human hematopoietic stem cells using nanostraws](
Ludwig Schmiderer, Agatheeswaran Subramaniam, Kristijonas Žemaitis, Alexandra Bäckström, David Yudovich, Svetlana Soboleva, Roman Galeev, Christelle N. Prinz, Jonas Larsson, and Martin Hjort
Physics
[Superconductivity in undoped BaFe2As2 by tetrahedral geometry design](
Jong-Hoon Kang, Jong-Woo Kim, Philip J. Ryan, Lin Xie, Lu Guo, Chris Sundahl, Jonathon Schad, Neil Campbell, Yesusa G. Collantes, Eric E. Hellstrom, Mark S. Rzchowski, and Chang-Beom Eom
Statistics
[Contrast trees and distribution boosting](
Jerome H. Friedman
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Social Sciences
Economic Sciences
[Deconstructing bias in social preferences reveals groupy and not-groupy behavior](
Rachel Kranton, Matthew Pease, Seth Sanders, and Scott Huettel
[Physician–patient racial concordance and disparities in birthing mortality for newborns](
Brad N. Greenwood, Rachel R. Hardeman, Laura Huang, and Aaron Sojourner
Political Sciences
[Explaining the homogeneous diffusion of COVID-19 nonpharmaceutical interventions across heterogeneous countries](
Abiel Sebhatu, Karl Wennberg, Stefan Arora-Jonsson, and Staffan I. Lindberg
Psychological and Cognitive Sciences
[Sleepiness, sleep duration, and human social activity: An investigation into bidirectionality using longitudinal time-use data](
Benjamin C. Holding, Tina Sundelin, Helena Schiller, Torbjörn Åkerstedt, Göran Kecklund, and John Axelsson
[The objectivity illusion and voter polarization in the 2016 presidential election](
Michael C. Schwalbe, Geoffrey L. Cohen, and Lee D. Ross
[Naming guides how 12-month-old infants encode and remember objects](
Alexander S. LaTourrette and Sandra R. Waxman
[Psychological foundations of human status allocation](
Patrick K. Durkee, Aaron W. Lukaszewski, and David M. Buss
[NTRK2 methylation is related to reduced PTSD risk in two African cohorts of trauma survivors](
Vanja Vukojevic, David Coynel, Navid R. Ghaffari, Virginie Freytag, Thomas Elbert, Iris-Tatjana Kolassa, Sarah Wilker, James L. McGaugh, Andreas Papassotiropoulos, and Dominique J.-F. de Quervain
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Biological Sciences
Agricultural Sciences
[Root angle modifications by the DRO1 homolog improve rice yields in saline paddy fields](
Yuka Kitomi, Eiko Hanzawa, Noriyuki Kuya, Haruhiko Inoue, Naho Hara, Sawako Kawai, Noriko Kanno, Masaki Endo, Kazuhiko Sugimoto, Toshimasa Yamazaki, Shingo Sakamoto, Naoki Sentoku, Jianzhong Wu, Hitoshi Kanno, Nobutaka Mitsuda, Kinya Toriyama, Tadashi Sato, and Yusaku Uga
Anthropology
[Covariation of fetal skull and maternal pelvis during the perinatal period in rhesus macaques and evolution of childbirth in primates](
Mikaze Kawada, Masato Nakatsukasa, Takeshi Nishimura, Akihisa Kaneko, and Naoki Morimoto
Applied Biological Sciences
[Ultraflexible organic light-emitting diodes for optogenetic nerve stimulation](
Dongmin Kim, Tomoyuki Yokota, Toshiki Suzuki, Sunghoon Lee, Taeseong Woo, Wakako Yukita, Mari Koizumi, Yutaro Tachibana, Hiromu Yawo, Hiroshi Onodera, Masaki Sekino, and Takao Someya
[Nuclear mechanosensing controls MSC osteogenic potential through HDAC epigenetic remodeling](
Anouk R. Killaars, Cierra J. Walker, and Kristi S. Anseth
[Efficient and nontoxic biomolecule delivery to primary human hematopoietic stem cells using nanostraws](
Ludwig Schmiderer, Agatheeswaran Subramaniam, Kristijonas Žemaitis, Alexandra Bäckström, David Yudovich, Svetlana Soboleva, Roman Galeev, Christelle N. Prinz, Jonas Larsson, and Martin Hjort
Biochemistry
[How a B family DNA polymerase has been evolved to copy RNA](
Woo Suk Choi, Peng He, Arti Pothukuchy, Jimmy Gollihar, Andrew D. Ellington, and Wei Yang
[Structural basis for amino acid exchange by a human heteromeric amino acid transporter](
Di Wu, Tamara N. Grund, Sonja Welsch, Deryck J. Mills, Max Michel, Schara Safarian, and Hartmut Michel
[Selenoprotein N is an endoplasmic reticulum calcium sensor that links luminal calcium levels to a redox activity](
Alexander Chernorudskiy, Ersilia Varone, Sara Francesca Colombo, Stefano Fumagalli, Alfredo Cagnotto, Angela Cattaneo, Mickael Briens, Mireille Baltzinger, Lauriane Kuhn, Angela Bachi, Andrea Berardi, Mario Salmona, Giovanna Musco, Nica Borgese, Alain Lescure, and Ester Zito
[An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins](
D. Judy Shon, Stacy A. Malaker, Kayvon Pedram, Emily Yang, Venkatesh Krishnan, Oliver Dorigo, and Carolyn R. Bertozzi
[A cryptic tubulin-binding domain links MEKK1 to curved tubulin protomers](
Pavel Filipčík, Sharissa L. Latham, Antonia L. Cadell, Catherine L. Day, David R. Croucher, and Peter D. Mace
[Cdc48 cofactor Shp1 regulates signal-induced SCFMet30 disassembly](
Linda Lauinger, Karin Flick, James L. Yen, Radhika Mathur, and Peter Kaiser
Biophysics and Computational Biology
[A β-barrel for oil transport through lipid membranes: Dynamic NMR structures of AlkL](
Tobias Schubeis, Tanguy Le Marchand, Csaba Daday, Wojciech Kopec, Kumar Tekwani Movellan, Jan Stanek, Tom S. Schwarzer, Kathrin Castiglione, Bert L. de Groot, Guido Pintacuda, and Loren B. Andreas
[Universal free-energy landscape produces efficient and reversible electron bifurcation](
J. L. Yuly, P. Zhang, C. E. Lubner, J. W. Peters, and D. N. Beratan
[Single-molecule diffusometry reveals no catalysis-induced diffusion enhancement of alkaline phosphatase as proposed by FCS experiments](
Zhijie Chen, Alan Shaw, Hugh Wilson, Maxime Woringer, Xavier Darzacq, Susan Marqusee, Quan Wang, and Carlos Bustamante
[The αβTCR mechanosensor exploits dynamic ectodomain allostery to optimize its ligand recognition site](
Wonmuk Hwang, Robert J. Mallis, Matthew J. Lang, and Ellis L. Reinherz
[Talin folding as the tuning fork of cellular mechanotransduction](
Rafael Tapia-Rojo, Álvaro Alonso-Caballero, and Julio M. Fernández
[Yeast ATM and ATR kinases use different mechanisms to spread histone H2A phosphorylation around a DNA double-strand break](
Kevin Li, Gabriel Bronk, Jane Kondev, and James E. Haber
[A method for scoring the cell type-specific impacts of noncoding variants in personal genomes](
Wenran Li, Zhana Duren, Rui Jiang, and Wing Hung Wong
[A robust and interpretable end-to-end deep learning model for cytometry data](
Zicheng Hu, Alice Tang, Jaiveer Singh, Sanchita Bhattacharya, and Atul J. Butte
[Objective assessment of stored blood quality by deep learning](
Minh Doan, Joseph A. Sebastian, Juan C. Caicedo, Stefanie Siegert, Aline Roch, Tracey R. Turner, Olga Mykhailova, Ruben N. Pinto, Claire McQuin, Allen Goodman, Michael J. Parsons, Olaf Wolkenhauer, Holger Hennig, Shantanu Singh, Anne Wilson, Jason P. Acker, Paul Rees, Michael C. Kolios, and Anne E. Carpenter
[Decoding three distinct states of the Syntaxin17 SNARE motif in mediating autophagosome–lysosome fusion](
Ying Li, Xiaofang Cheng, Miao Li, Yingli Wang, Tao Fu, Zixuan Zhou, Yaru Wang, Xinyu Gong, Xiaolong Xu, Jianping Liu, and Lifeng Pan
[Phosphorylated CtIP bridges DNA to promote annealing of broken ends](
Robin Öz, Sean M. Howard, Rajhans Sharma, Hanna Törnkvist, Ilaria Ceppi, Sriram KK, Erik Kristiansson, Petr Cejka, and Fredrik Westerlund
[Intrinsically disordered linkers control tethered kinases via effective concentration](
Mateusz Dyla and Magnus Kjaergaard
Cell Biology
[The glutathione peroxidase 8 (GPX8)/IL-6/STAT3 axis is essential in maintaining an aggressive breast cancer phenotype](
Anees Khatib, Balakrishnan Solaimuthu, Michal Ben Yosef, Areej Abu Rmaileh, Mayur Tanna, Gidi Oren, Michal Schlesinger Frisch, Jonathan H. Axelrod, Michal Lichtenstein, and Yoav D. Shaul
[Uncovering targeting priority to yeast peroxisomes using an in-cell competition assay](
Mira Rosenthal, Eyal Metzl-Raz, Jérôme Bürgi, Eden Yifrach, Layla Drwesh, Amir Fadel, Yoav Peleg, Doron Rapaport, Matthias Wilmanns, Naama Barkai, Maya Schuldiner, and Einat Zalckvar
[The m6A RNA demethylase FTO is a HIF-independent synthetic lethal partner with the VHL tumor suppressor](
Yiren Xiao, Kaushik N. Thakkar, Hongjuan Zhao, James Broughton, Yang Li, Jose A. Seoane, Anh N. Diep, Thomas J. Metzner, Rie von Eyben, David L. Dill, James D. Brooks, Christina Curtis, John T. Leppert, Jiangbin Ye, Donna M. Peehl, Amato J. Giaccia, Subarna Sinha, and Erinn B. Rankin
Developmental Biology
[Enhancer dependence of cell-type–specific gene expression increases with developmental age](
Wenqing Cai, Jialiang Huang, Qian Zhu, Bin E. Li, Davide Seruggia, Pingzhu Zhou, Minh Nguyen, Yuko Fujiwara, Huafeng Xie, Zhenggang Yang, Danni Hong, Pengfei Ren, Jian Xu, William T. Pu, Guo-Cheng Yuan, and Stuart H. Orkin
[Bacteria- and temperature-regulated peptides modulate β-catenin signaling in Hydra](
Jan Taubenheim, Doris Willoweit-Ohl, Mirjam Knop, Sören Franzenburg, Jinru He, Thomas C. G. Bosch, and Sebastian Fraune
[A specialized population of Periostin-expressing cardiac fibroblasts contributes to postnatal cardiomyocyte maturation and innervation](
Luis Hortells, Iñigo Valiente-Alandi, Zachary M. Thomas, Emma J. Agnew, Dan J. Schnell, Allen J. York, Ronald J. Vagnozzi, Evan C. Meyer, Jeffery D. Molkentin, and Katherine E. Yutzey
Ecology
[Decreasing snow cover alters functional composition and diversity of Arctic tundra](
Pekka Niittynen, Risto K. Heikkinen, and Miska Luoto
Environmental Sciences
[Siberian and temperate ecosystems shape Northern Hemisphere atmospheric CO2 seasonal amplification](
Xin Lin, Brendan M. Rogers, Colm Sweeney, Frédéric Chevallier, Mikhail Arshinov, Edward Dlugokencky, Toshinobu Machida, Motoki Sasakawa, Pieter Tans, and Gretchen Keppel-Aleks
[Diel variability of methane emissions from lakes](
Anna K. Sieczko, Nguyen Thanh Duc, Jonathan Schenk, Gustav Pajala, David Rudberg, Henrique O. Sawakuchi, and David Bastviken
Evolution
[The macroevolutionary dynamics of symbiotic and phenotypic diversification in lichens](
Matthew P. Nelsen, Robert Lücking, C. Kevin Boyce, H. Thorsten Lumbsch, and Richard H. Ree
Genetics
[Integrity of a heterochromatic domain ensured by its boundary elements](
Sebastian Jespersen Charlton, Maria Mønster Jørgensen, and Geneviève Thon
Immunology and Inflammation
[Autoantibodies against central nervous system antigens in a subset of B cell–dominant multiple sclerosis patients](
Stefanie Kuerten, Tobias V. Lanz, Nithya Lingampalli, Lauren J. Lahey, Christoph Kleinschnitz, Mathias Mäurer, Michael Schroeter, Stefan Braune, Tjalf Ziemssen, Peggy P. Ho, William H. Robinson, and Lawrence Steinman
[Indoles from the commensal microbiota act via the AHR and IL-10 to tune the cellular composition of the colonic epithelium during aging](
Domonica N. Powell, Alyson Swimm, Robert Sonowal, Alexis Bretin, Andrew T. Gewirtz, Rheinallt M. Jones, and Daniel Kalman
[Anacardic acid induces IL-33 and promotes remyelination in CNS](
Åsa Ljunggren-Rose, Chandramohan Natarajan, Pranathi Matta, Akansha Pandey, Isha Upender, and Subramaniam Sriram
[Defined microbiota transplant restores Th17/RORγt+ regulatory T cell balance in mice colonized with inflammatory bowel disease microbiotas](
Graham J. Britton, Eduardo J. Contijoch, Matthew P. Spindler, Varun Aggarwala, Belgin Dogan, Gerold Bongers, Lani San Mateo, Andrew Baltus, Anuk Das, Dirk Gevers, Thomas J. Borody, Nadeem O. Kaakoush, Michael A. Kamm, Hazel Mitchell, Sudarshan Paramsothy, Jose C. Clemente, Jean-Frederic Colombel, Kenneth W. Simpson, Marla C. Dubinsky, Ari Grinspan, and Jeremiah J. Faith
[Immune signatures of prodromal multiple sclerosis in monozygotic twins](
Lisa Ann Gerdes, Claudia Janoschka, Maria Eveslage, Bianca Mannig, Timo Wirth, Andreas Schulte-Mecklenbeck, Sarah Lauks, Laura Glau, Catharina C. Gross, Eva Tolosa, Andrea Flierl-Hecht, Birgit Ertl-Wagner, Frederik Barkhof, Sven G. Meuth, Tania Kümpfel, Heinz Wiendl, Reinhard Hohlfeld, and Luisa Klotz
[IL-12 p40 monomer is different from other IL-12 family members to selectively inhibit IL-12Rβ1 internalization and suppress EAE](
Susanta Mondal, Madhuchhanda Kundu, Malabendu Jana, Avik Roy, Suresh B. Rangasamy, Khushbu K. Modi, Jennillee Wallace, Yasmeen A. Albalawi, Roumen Balabanov, and Kalipada Pahan
[KAT5 acetylates cGAS to promote innate immune response to DNA virus](
Ze-Min Song, Heng Lin, Xue-Mei Yi, Wei Guo, Ming-Ming Hu, and Hong-Bing Shu
Medical Sciences
[Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellular cancer progression](
Anna Fishbein, Weicang Wang, Haixia Yang, Jun Yang, Victoria M. Hallisey, Jianjun Deng, Sanne M. L. Verheul, Sung Hee Hwang, Allison Gartung, Yuxin Wang, Diane R. Bielenberg, Sui Huang, Mark W. Kieran, Bruce D. Hammock, and Dipak Panigrahy
[Multiple myeloma cells are exceptionally sensitive to heat shock, which overwhelms their proteostasis network and induces apoptosis](
Zhe Sha and Alfred L. Goldberg
[Suppressing neutrophil-dependent angiogenesis abrogates resistance to anti-VEGF antibody in a genetic model of colorectal cancer](
Yoshiro Itatani, Takamasa Yamamoto, Cuiling Zhong, Alfredo A. Molinolo, Jane Ruppel, Priti Hegde, M. Mark Taketo, and Napoleone Ferrara
[Circadian regulation of c-MYC in mice](
Zhenxing Liu, Christopher P. Selby, Yanyan Yang, Laura A. Lindsey-Boltz, Xuemei Cao, Khagani Eynullazada, and Aziz Sancar
Microbiology
[Global epigenomic analysis of KSHV-infected primary effusion lymphoma identifies functional MYC superenhancers and enhancer RNAs](
Angela Park, Soohwan Oh, Kyle L. Jung, Un Yung Choi, Hye-Ra Lee, Michael G. Rosenfeld, and Jae U. Jung
[NusG controls transcription pausing and RNA polymerase translocation throughout the Bacillus subtilis genome](
Alexander V. Yakhnin, Peter C. FitzGerald, Carl McIntosh, Helen Yakhnin, Maria Kireeva, Joshua Turek-Herman, Zachary F. Mandell, Mikhail Kashlev, and Paul Babitzke
[Rapid formation of human immunodeficiency virus-like particles](
Joanna Bednarska, Annegret Pelchen-Matthews, Pavel Novak, Jemima J. Burden, Peter A. Summers, Marina K. Kuimova, Yuri Korchev, Mark Marsh, and Andrew Shevchuk
[One gene, multiple ecological strategies: A biofilm regulator is a capacitor for sustainable diversity](
Eisha Mhatre, Daniel J. Snyder, Emily Sileo, Caroline B. Turner, Sean W. Buskirk, Nicolas L. Fernandez, Matthew B. Neiditch, Christopher M. Waters, and Vaughn S. Cooper
[Molecular causes of an evolutionary shift along the parasitism–mutualism continuum in a bacterial symbiont](
Paul Herrera, Lisa Schuster, Cecilia Wentrup, Lena König, Thomas Kempinger, Hyunsoo Na, Jasmin Schwarz, Stephan Köstlbacher, Florian Wascher, Markus Zojer, Thomas Rattei, and Matthias Horn
Neuroscience
[NTRK2 methylation is related to reduced PTSD risk in two African cohorts of trauma survivors](
Vanja Vukojevic, David Coynel, Navid R. Ghaffari, Virginie Freytag, Thomas Elbert, Iris-Tatjana Kolassa, Sarah Wilker, James L. McGaugh, Andreas Papassotiropoulos, and Dominique J.-F. de Quervain
[A supergene-linked estrogen receptor drives alternative phenotypes in a polymorphic songbird](
Jennifer R. Merritt, Kathleen E. Grogan, Wendy M. Zinzow-Kramer, Dan Sun, Eric A. Ortlund, Soojin V. Yi, and Donna L. Maney
[Divergence of rodent and primate medial frontal cortex functional connectivity](
David J. Schaeffer, Yuki Hori, Kyle M. Gilbert, Joseph S. Gati, Ravi S. Menon, and Stefan Everling
[The Atoh7 remote enhancer provides transcriptional robustness during retinal ganglion cell development](
Joel B. Miesfeld, Noor M. Ghiasvand, Brennan Marsh-Armstrong, Nicholas Marsh-Armstrong, Eric B. Miller, Pengfei Zhang, Suman K. Manna, Robert J. Zawadzki, Nadean L. Brown, and Tom Glaser
[Calcium flares and compartmentalization in rod photoreceptors](
Yunzhen Li, Fabio Falleroni, Simone Mortal, Ulisse Bocchero, Dan Cojoc, and Vincent Torre
Pharmacology
[Illuminating the allosteric modulation of the calcium-sensing receptor](
Hongkang Liu, Ping Yi, Wenjing Zhao, Yuling Wu, Francine Acher, Jean-Philippe Pin, Jianfeng Liu, and Philippe Rondard
[Agonist-induced formation of unproductive receptor-G12 complexes](
Najeah Okashah, Shane C. Wright, Kouki Kawakami, Signe Mathiasen, Joris Zhou, Sumin Lu, Jonathan A. Javitch, Asuka Inoue, Michel Bouvier, and Nevin A. Lambert
Physiology
[Coupled transmembrane mechanisms control MCU-mediated mitochondrial Ca2+ uptake](
Horia Vais, Riley Payne, Usha Paudel, Carmen Li, and J. Kevin Foskett
[Simple binding of protein kinase A prior to phosphorylation allows CFTR anion channels to be opened by nucleotides](
Csaba Mihályi, Iordan Iordanov, Beáta Töröcsik, and László Csanády
Plant Biology
[Maize ANT1 modulates vascular development, chloroplast development, photosynthesis, and plant growth](
Wen-Yu Liu, Hsin-Hung Lin, Chun-Ping Yu, Chao-Kang Chang, Hsiang-June Chen, Jinn-Jy Lin, Mei-Yeh Jade Lu, Shih-Long Tu, Shin-Han Shiu, Shu-Hsing Wu, Maurice S. B. Ku, and Wen-Hsiung Li
[The karrikin signaling regulator SMAX1 controls Lotus japonicus root and root hair development by suppressing ethylene biosynthesis](
Samy Carbonnel, Debatosh Das, Kartikye Varshney, Markus C. Kolodziej, José A. Villaécija-Aguilar, and Caroline Gutjahr
[DROOPY LEAF1 controls leaf architecture by orchestrating early brassinosteroid signaling](
Meicheng Zhao, Sha Tang, Haoshan Zhang, Miaomiao He, Jihong Liu, Hui Zhi, Yi Sui, Xiaotong Liu, Guanqing Jia, Zhiying Zhao, Jijun Yan, Baocai Zhang, Yihua Zhou, Jinfang Chu, Xingchun Wang, Baohua Zhao, Wenqiang Tang, Jiayang Li, Chuanyin Wu, Xigang Liu, and Xianmin Diao
[Light-induced psbA translation in plants is triggered by photosystem II damage via an assembly-linked autoregulatory circuit](
Prakitchai Chotewutmontri and Alice Barkan
[mRNA adenosine methylase (MTA) deposits m6A on pri-miRNAs to modulate miRNA biogenesis in Arabidopsis thaliana](
Susheel Sagar Bhat, Dawid Bielewicz, Tomasz Gulanicz, Zsuzsanna Bodi, Xiang Yu, Stephen J. Anderson, Lukasz Szewc, Mateusz Bajczyk, Jakub Dolata, Natalia Grzelak, Dariusz J. Smolinski, Brian D. Gregory, Rupert G. Fray, Artur Jarmolowski, and Zofia Szweykowska-Kulinska
[Synthetic conversion of leaf chloroplasts into carotenoid-rich plastids reveals mechanistic basis of natural chromoplast development](
Briardo Llorente, Salvador Torres-Montilla, Luca Morelli, Igor Florez-Sarasa, José Tomás Matus, Miguel Ezquerro, Lucio D’Andrea, Fakhreddine Houhou, Eszter Majer, Belén Picó, Jaime Cebolla, Adrian Troncoso, Alisdair R. Fernie, José-Antonio Daròs, and Manuel Rodriguez-Concepcion
Psychological and Cognitive Sciences
[Sleepiness, sleep duration, and human social activity: An investigation into bidirectionality using longitudinal time-use data](
Benjamin C. Holding, Tina Sundelin, Helena Schiller, Torbjörn Åkerstedt, Göran Kecklund, and John Axelsson
Systems Biology
[Proteome reallocation from amino acid biosynthesis to ribosomes enables yeast to grow faster in rich media](
Johan Björkeroth, Kate Campbell, Carl Malina, Rosemary Yu, Francesca Di Bartolomeo, and Jens Nielsen
[Multiomic blood correlates of genetic risk identify presymptomatic disease alterations](
Michael Wainberg, Andrew T. Magis, John C. Earls, Jennifer C. Lovejoy, Nasa Sinnott-Armstrong, Gilbert S. Omenn, Leroy Hood, and Nathan D. Price
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Corrections
[Correction for Bhattacharya et al., Lipid sponge droplets as programmable synthetic organelles](
[Correction for Greenway et al., Convergent evolution of conserved mitochondrial pathways underlies repeated adaptation to extreme environments](
[Correction for Lim et al., Inhibition of DUX4 expression with antisense LNA gapmers as a therapy for facioscapulohumeral muscular dystrophy](
[Correction for Latoscha et al., c-di-AMP hydrolysis by the phosphodiesterase AtaC promotes differentiation of multicellular bacteria](
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