PNAS Table of Contents for August 18, 2020; Vol. 117, No. 33

[PNAS] [2021 NAS Awards](/cgi/adclick/?ad=55145&adclick=true&url=http%3A%2F%2Fwww.nasonline.org%2Fprograms%2Fawards%2F2021.html)   [August 18, 2020; Vol. 117, No. 33]( ) This Week in PNAS [In This Issue]( --------------------------------------------------------------- Opinion [Opinion: Here’s how we restore productivity and vigor to the biomedical research workforce in the midst of COVID-19]( M. Bishr Omary and Mahmud Hassan Leading scientists discuss current issues. --------------------------------------------------------------- Commentaries [FROG/B reporter gives bright insights into redox biology]( Ricardo A. Wolosiuk [Complex self-assembled lattices from simple polymer blends]( Zebin Su, Mingjun Huang, and Stephen Z. D. Cheng [The heart of the HIV RNA packaging signal?]( Alan Rein [Linking neurons to immunity: Lessons from Hydra]( Yuuki Obata and Vassilis Pachnis [Metformin treatment of the C9orf72 ALS/FTD mouse: Almost too good for words]( Michael Rosbash --------------------------------------------------------------- Perspective [Shedding new light on the generation of the visual chromophore]( Krzysztof Palczewski and Philip D. Kiser --------------------------------------------------------------- Letters [No waves of intelligent design]( Eugene V. Koonin, Yuri I. Wolf, and Mikhail I. Katsnelson [Reply to Koonin et al.: Evolution of proteins is Darwinian]( J. C. Phillips --------------------------------------------------------------- Brief Reports [Explaining the low-frequency shear elasticity of confined liquids]( Alessio Zaccone and Kostya Trachenko [RCP8.5 tracks cumulative CO2 emissions]( Christopher R. Schwalm, Spencer Glendon, and Philip B. Duffy [Social distancing responses to COVID-19 emergency declarations strongly differentiated by income]( Joakim A. Weill, Matthieu Stigler, Olivier Deschenes, and Michael R. Springborn [Acetylated histone H4 tail enhances histone H3 tail acetylation by altering their mutual dynamics in the nucleosome]( Ayako Furukawa, Masatoshi Wakamori, Yasuhiro Arimura, Hideaki Ohtomo, Yasuo Tsunaka, Hitoshi Kurumizaka, Takashi Umehara, and Yoshifumi Nishimura --------------------------------------------------------------- Physical Sciences Applied Mathematics [Geometric anomaly detection in data]( Bernadette J. Stolz, Jared Tanner, Heather A. Harrington, and Vidit Nanda Applied Physical Sciences [In-place molecular preservation of cellulose in 5,000-year-old archaeological textiles]( Corentin Reynaud, Mathieu Thoury, Alexandre Dazzi, Gaël Latour, Mario Scheel, Jiayi Li, Ariane Thomas, Christophe Moulhérat, Aurore Didier, and Loïc Bertrand [Surface polarization effects in confined polyelectrolyte solutions]( Debarshee Bagchi, Trung Dac Nguyen, and Monica Olvera de la Cruz [Superconductivity enhancement in phase-engineered molybdenum carbide/disulfide vertical heterostructures]( Fu Zhang, Wenkai Zheng, Yanfu Lu, Lavish Pabbi, Kazunori Fujisawa, Ana Laura Elías, Anna R. Binion, Tomotaroh Granzier-Nakajima, Tianyi Zhang, Yu Lei, Zhong Lin, Eric W. Hudson, Susan B. Sinnott, Luis Balicas, and Mauricio Terrones Biophysics and Computational Biology [Eco-evolutionary control of pathogens]( Michael Lässig and Ville Mustonen [A TDDFT investigation of the Photosystem II reaction center: Insights into the precursors to charge separation]( Maeve A. Kavanagh, Joshua K. G. Karlsson, Jonathan D. Colburn, Laura M. C. Barter, and Ian R. Gould [Direct imaging of liquid domains in membranes by cryo-electron tomography]( Caitlin E. Cornell, Alexander Mileant, Niket Thakkar, Kelly K. Lee, and Sarah L. Keller [The structure of protein dynamic space]( S. Rackovsky and Harold A. Scheraga [Optimizing immunization protocols to elicit broadly neutralizing antibodies]( Kayla G. Sprenger, Joy E. Louveau, Pranav M. Murugan, and Arup K. Chakraborty [Spatiotemporal mapping of bacterial membrane potential responses to extracellular electron transfer]( Sahand Pirbadian, Marko S. Chavez, and Mohamed Y. El-Naggar Chemistry [Observing 3-hydroxyanthranilate-3,4-dioxygenase in action through a crystalline lens]( Yifan Wang, Kathy Fange Liu, Yu Yang, Ian Davis, and Aimin Liu [Revealing the origin of multiphasic dynamic behaviors in cyanobacteriochrome]( Dihao Wang, Xiankun Li, Sheng Zhang, Lijuan Wang, Xiaojing Yang, and Dongping Zhong [Specific targeting of ovarian tumor-associated macrophages by large, anionic nanoparticles]( Tom Haber, Yvonne R. Cornejo, Soraya Aramburo, Linda Flores, Pengpeng Cao, Alice Liu, Rachael Mooney, Megan Gilchrist, Revathiswari Tirughana, Ugochi Nwokafor, Wafa Abidi, Ernest Han, Thanh Dellinger, Mark T. Wakabayashi, Karen S. Aboody, and Jacob M. Berlin [Dielectric response with short-ranged electrostatics]( Stephen J. Cox [RNA sectors and allosteric function within the ribosome]( Allison S. Walker, William P. Russ, Rama Ranganathan, and Alanna Schepartz [Differences in the free energies between the excited states of Aβ40 and Aβ42 monomers encode their aggregation propensities]( Debayan Chakraborty, John E. Straub, and D. Thirumalai Earth, Atmospheric, and Planetary Sciences [Global snow drought hot spots and characteristics]( Laurie S. Huning and Amir AghaKouchak [Three-dimensional reconstructions of the putative metazoan Namapoikia show that it was a microbial construction]( Akshay Mehra, Wesley A. Watters, John P. Grotzinger, and Adam C. Maloof Physics [Nonreciprocity as a generic route to traveling states]( Zhihong You, Aparna Baskaran, and M. Cristina Marchetti [Nanoscale force sensing of an ultrafast nonlinear optical response]( Zeno Schumacher, Rasa Rejali, Raphael Pachlatko, Andreas Spielhofer, Philipp Nagler, Yoichi Miyahara, David G. Cooke, and Peter Grütter [Geometric renormalization unravels self-similarity of the multiscale human connectome]( Muhua Zheng, Antoine Allard, Patric Hagmann, Yasser Alemán-Gómez, and M. Ángeles Serrano Sustainability Science [Revealing the intersectoral material flow of plastic containers and packaging in Japan]( Jun Nakatani, Tamon Maruyama, and Yuichi Moriguchi --------------------------------------------------------------- Social Sciences Anthropology [The rise and fall of viticulture in the Late Antique Negev Highlands reconstructed from archaeobotanical and ceramic data]( Daniel Fuks, Guy Bar-Oz, Yotam Tepper, Tali Erickson-Gini, Dafna Langgut, Lior Weissbrod, and Ehud Weiss [Stable isotopes in hair reveal dietary protein sources with links to socioeconomic status and health]( James R. Ehleringer, Stephannie Covarrubias Avalos, Brett J. Tipple, Luciano O. Valenzuela, and Thure E. Cerling [Social bonds do not mediate the relationship between early adversity and adult glucocorticoids in wild baboons]( Stacy Rosenbaum, Shuxi Zeng, Fernando A. Campos, Laurence R. Gesquiere, Jeanne Altmann, Susan C. Alberts, Fan Li, and Elizabeth A. Archie Economic Sciences [Popular repugnance contrasts with legal bans on controversial markets]( Alvin E. Roth and Stephanie W. Wang Psychological and Cognitive Sciences [Heuristics and optimal solutions to the breadth–depth dilemma]( Rubén Moreno-Bote, Jorge Ramírez-Ruiz, Jan Drugowitsch, and Benjamin Y. Hayden [An objective evaluation of the beholder’s response to abstract and figurative art based on construal level theory]( Celia Durkin, Eileen Hartnett, Daphna Shohamy, and Eric R. Kandel [Historically rice-farming societies have tighter social norms in China and worldwide]( Thomas Talhelm and Alexander S. English [Gaze deflection reveals how gaze cueing is tuned to extract the mind behind the eyes]( Clara Colombatto, Yi-Chia Chen, and Brian J. Scholl [The creative cliff illusion]( Brian J. Lucas and Loran F. Nordgren Social Sciences [Interdependence and the cost of uncoordinated responses to COVID-19]( David Holtz, Michael Zhao, Seth G. Benzell, Cathy Y. Cao, Mohammad Amin Rahimian, Jeremy Yang, Jennifer Allen, Avinash Collis, Alex Moehring, Tara Sowrirajan, Dipayan Ghosh, Yunhao Zhang, Paramveer S. Dhillon, Christos Nicolaides, Dean Eckles, and Sinan Aral Sustainability Science [Revealing the intersectoral material flow of plastic containers and packaging in Japan]( Jun Nakatani, Tamon Maruyama, and Yuichi Moriguchi --------------------------------------------------------------- Biological Sciences Anthropology [In-place molecular preservation of cellulose in 5,000-year-old archaeological textiles]( Corentin Reynaud, Mathieu Thoury, Alexandre Dazzi, Gaël Latour, Mario Scheel, Jiayi Li, Ariane Thomas, Christophe Moulhérat, Aurore Didier, and Loïc Bertrand Applied Biological Sciences [Inducers of the endothelial cell barrier identified through chemogenomic screening in genome-edited hPSC-endothelial cells]( Filip Roudnicky, Jitao David Zhang, Bo Kyoung Kim, Nikhil J. Pandya, Yanjun Lan, Lisa Sach-Peltason, Heloise Ragelle, Pamela Strassburger, Sabine Gruener, Mirjana Lazendic, Sabine Uhles, Franco Revelant, Oliv Eidam, Gregor Sturm, Verena Kueppers, Klaus Christensen, Leonard D. Goldstein, Manuel Tzouros, Balazs Banfai, Zora Modrusan, Martin Graf, Christoph Patsch, Mark Burcin, Claas A. Meyer, Peter D. Westenskow, and Chad A. Cowan [A global view on how local muscular fatigue affects human performance]( Márcio F. Goethel, Mauro Gonçalves, Cayque Brietzke, Adalgiso C. Cardozo, João P. Vilas-Boas, and Ulysses F. Ervilha [Timing social distancing to avert unmanageable COVID-19 hospital surges]( Daniel Duque, David P. Morton, Bismark Singh, Zhanwei Du, Remy Pasco, and Lauren Ancel Meyers Biochemistry [Observing 3-hydroxyanthranilate-3,4-dioxygenase in action through a crystalline lens]( Yifan Wang, Kathy Fange Liu, Yu Yang, Ian Davis, and Aimin Liu [RNA sectors and allosteric function within the ribosome]( Allison S. Walker, William P. Russ, Rama Ranganathan, and Alanna Schepartz [JMJD5 couples with CDK9 to release the paused RNA polymerase II]( Haolin Liu, Srinivas Ramachandran, Nova Fong, Tzu Phang, Schuyler Lee, Pirooz Parsa, Xinjian Liu, Laura Harmacek, Thomas Danhorn, Tengyao Song, Sangphil Oh, Qianqian Zhang, Zhongzhou Chen, Qian Zhang, Ting-Hui Tu, Carrie Happoldt, Brian O’Conner, Ralf Janknecht, Chuan-Yuan Li, Philippa Marrack, John Kappler, Sonia Leach, and Gongyi Zhang [Convergent evolution of processivity in bacterial and fungal cellulases]( Taku Uchiyama, Takayuki Uchihashi, Akihiko Nakamura, Hiroki Watanabe, Satoshi Kaneko, Masahiro Samejima, and Kiyohiko Igarashi [Insights into the evolution of regulated actin dynamics via characterization of primitive gelsolin/cofilin proteins from Asgard archaea]( Caner Akıl, Linh T. Tran, Magali Orhant-Prioux, Yohendran Baskaran, Edward Manser, Laurent Blanchoin, and Robert C. Robinson [Structural basis for carotenoid cleavage by an archaeal carotenoid dioxygenase]( Anahita Daruwalla, Jianye Zhang, Ho Jun Lee, Nimesh Khadka, Erik R. Farquhar, Wuxian Shi, Johannes von Lintig, and Philip D. Kiser Biophysics and Computational Biology [Structures of filamentous viruses infecting hyperthermophilic archaea explain DNA stabilization in extreme environments]( Fengbin Wang, Diana P. Baquero, Leticia C. Beltran, Zhangli Su, Tomasz Osinski, Weili Zheng, David Prangishvili, Mart Krupovic, and Edward H. Egelman [A TDDFT investigation of the Photosystem II reaction center: Insights into the precursors to charge separation]( Maeve A. Kavanagh, Joshua K. G. Karlsson, Jonathan D. Colburn, Laura M. C. Barter, and Ian R. Gould [Direct imaging of liquid domains in membranes by cryo-electron tomography]( Caitlin E. Cornell, Alexander Mileant, Niket Thakkar, Kelly K. Lee, and Sarah L. Keller [Revealing the origin of multiphasic dynamic behaviors in cyanobacteriochrome]( Dihao Wang, Xiankun Li, Sheng Zhang, Lijuan Wang, Xiaojing Yang, and Dongping Zhong [Differences in the free energies between the excited states of Aβ40 and Aβ42 monomers encode their aggregation propensities]( Debayan Chakraborty, John E. Straub, and D. Thirumalai [The structure of protein dynamic space]( S. Rackovsky and Harold A. Scheraga [Direct label-free imaging of nanodomains in biomimetic and biological membranes by cryogenic electron microscopy]( Frederick A. Heberle, Milka Doktorova, Haden L. Scott, Allison D. Skinkle, M. Neal Waxham, and Ilya Levental [Energetics and kinetics of substrate analog-coupled staphylococcal nuclease folding revealed by a statistical mechanical approach]( Takuya Mizukami, Shunta Furuzawa, Satoru G. Itoh, Saho Segawa, Teikichi Ikura, Kunio Ihara, Hisashi Okumura, Heinrich Roder, and Kosuke Maki [Hidden kinetic traps in multidomain folding highlight the presence of a misfolded but functionally competent intermediate]( Candice Gautier, Francesca Troilo, Florence Cordier, Francesca Malagrinò, Angelo Toto, Lorenzo Visconti, Yanlei Zhu, Maurizio Brunori, Nicolas Wolff, and Stefano Gianni Cell Biology [Lysosomal activity regulates Caenorhabditis elegans mitochondrial dynamics through vitamin B12 metabolism]( Wei Wei and Gary Ruvkun [Identification of MYC as an antinecroptotic protein that stifles RIPK1–RIPK3 complex formation]( Daehyeon Seong, Manhyung Jeong, Jinho Seo, Ji-Yoon Lee, Chi Hyun Hwang, Ho-Chul Shin, Jeong Yoon Shin, Young Woo Nam, Jeong Yeon Jo, Haeseung Lee, Hye-Jung Kim, Hwa-Ryeon Kim, Ji Hoon Oh, Sang-Jun Ha, Seung Jun Kim, Jae-Seok Roe, Wankyu Kim, June-Won Cheong, Kwang-Hee Bae, Sang Chul Lee, Andrew Oberst, Peter Vandenabeele, Dong Hoon Shin, Eun-Woo Lee, and Jaewhan Song [Genome-wide RNA interference screening reveals a COPI-MAP2K3 pathway required for YAP regulation]( Yong Joon Kim, Eunji Jung, Eunbie Shin, Sin-Hyoung Hong, Hui Su Jeong, Gayeong Hur, Hye Yun Jeong, Seung-Hyo Lee, Ji Eun Lee, Gun-Hwa Kim, and Joon Kim [Activating KRAS, NRAS, and BRAF mutants enhance proteasome capacity and reduce endoplasmic reticulum stress in multiple myeloma]( Fazal Shirazi, Richard J. Jones, Ram K. Singh, Jianxuan Zou, Isere Kuiatse, Zuzana Berkova, Hua Wang, Hans C. Lee, Samuel Hong, Larry Dick, Nibedita Chattopadhyay, and Robert Z. Orlowski Developmental Biology [Two distinct pathways of pregranulosa cell differentiation support follicle formation in the mouse ovary]( Wanbao Niu and Allan C. Spradling Ecology [Plant richness, turnover, and evolutionary diversity track gradients of stability and ecological opportunity in a megadiversity center]( Jonathan F. Colville, Colin M. Beale, Félix Forest, Res Altwegg, Brian Huntley, and Richard M. Cowling [Global patterns and climatic controls of belowground net carbon fixation]( Laureano A. Gherardi and Osvaldo E. Sala Environmental Sciences [Stable isotopes in hair reveal dietary protein sources with links to socioeconomic status and health]( James R. Ehleringer, Stephannie Covarrubias Avalos, Brett J. Tipple, Luciano O. Valenzuela, and Thure E. Cerling Evolution [Eco-evolutionary control of pathogens]( Michael Lässig and Ville Mustonen [Social bonds do not mediate the relationship between early adversity and adult glucocorticoids in wild baboons]( Stacy Rosenbaum, Shuxi Zeng, Fernando A. Campos, Laurence R. Gesquiere, Jeanne Altmann, Susan C. Alberts, Fan Li, and Elizabeth A. Archie [Changes in life history and population size can explain the relative neutral diversity levels on X and autosomes in extant human populations]( Guy Amster, David A. Murphy, William R. Milligan, and Guy Sella Genetics [Genomic analysis of inherited hearing loss in the Palestinian population]( Amal Abu Rayyan, Lara Kamal, Silvia Casadei, Zippora Brownstein, Fouad Zahdeh, Hashem Shahin, Christina Canavati, Dima Dweik, Tamara Jaraysa, Grace Rabie, Ryan J. Carlson, Suleyman Gulsuner, Ming K. Lee, Karen B. Avraham, Tom Walsh, Mary-Claire King, and Moien N. Kanaan Immunology and Inflammation [Optimizing immunization protocols to elicit broadly neutralizing antibodies]( Kayla G. Sprenger, Joy E. Louveau, Pranav M. Murugan, and Arup K. Chakraborty [Regulatory T cells suppress Th17 cell Ca2+ signaling in the spinal cord during murine autoimmune neuroinflammation]( Shivashankar Othy, Amit Jairaman, Joseph L. Dynes, Tobias X. Dong, Cornelia Tune, Andriy V. Yeromin, Angel Zavala, Chijioke Akunwafo, Fangyi Chen, Ian Parker, and Michael D. Cahalan [Lsh/HELLS is required for B lymphocyte development and immunoglobulin class switch recombination]( Yafeng He, Jianke Ren, Xiaoping Xu, Kai Ni, Andrew Schwader, Richard Finney, Can Wang, Lei Sun, Kimberly Klarmann, Jonathan Keller, Anthony Tubbs, Andre Nussenzweig, and Kathrin Muegge [Necroptosis-based CRISPR knockout screen reveals Neuropilin-1 as a critical host factor for early stages of murine cytomegalovirus infection]( Rebecca K. Lane, Hongyan Guo, Amanda D. Fisher, Jonathan Diep, Zhao Lai, Yidong Chen, Jason W. Upton, Jan Carette, Edward S. Mocarski, and William J. Kaiser Medical Sciences [Multidimensional study of the heterogeneity of leukemia cells in t(8;21) acute myelogenous leukemia identifies the subtype with poor outcome]( Lu Jiang, Xue-Ping Li, Yu-Ting Dai, Bing Chen, Xiang-Qin Weng, Shu-Min Xiong, Min Zhang, Jin-Yan Huang, Zhu Chen, and Sai-Juan Chen [Modeling SHH-driven medulloblastoma with patient iPS cell-derived neural stem cells]( Evelyn Susanto, Ana Marin Navarro, Leilei Zhou, Anders Sundström, Niek van Bree, Marina Stantic, Mohsen Moslem, Jignesh Tailor, Jonne Rietdijk, Veronica Zubillaga, Jens-Martin Hübner, Holger Weishaupt, Johanna Wolfsberger, Irina Alafuzoff, Ann Nordgren, Thierry Magnaldo, Peter Siesjö, John Inge Johnsen, Marcel Kool, Kristiina Tammimies, Anna Darabi, Fredrik J. Swartling, Anna Falk, and Margareta Wilhelm [An ErbB2 splice variant lacking exon 16 drives lung carcinoma]( Harvey W. Smith, Lei Yang, Chen Ling, Arlan Walsh, Victor D. Martinez, Jonathan Boucher, Dongmei Zuo, Ethan S. Sokol, Dean C. Pavlick, Garrett M. Frampton, Juliann Chmielecki, Laura M. Jones, Philippe P. Roux, William W. Lockwood, and William J. Muller [Hypothalamic extended synaptotagmin-3 contributes to the development of dietary obesity and related metabolic disorders]( Yi Zhang, Yunliang Guan, Susu Pan, Lihong Yan, Ping Wang, Zhuo Chen, Qing Shen, Faming Zhao, Xin Zhang, Juan Li, Juxue Li, Dongsheng Cai, and Guo Zhang [ALKBH5 regulates anti–PD-1 therapy response by modulating lactate and suppressive immune cell accumulation in tumor microenvironment]( Na Li, Yuqi Kang, Lingling Wang, Sarah Huff, Rachel Tang, Hui Hui, Kriti Agrawal, Gwendolyn Michelle Gonzalez, Yinsheng Wang, Sandip Pravin Patel, and Tariq M. Rana Microbiology [Spatiotemporal mapping of bacterial membrane potential responses to extracellular electron transfer]( Sahand Pirbadian, Marko S. Chavez, and Mohamed Y. El-Naggar [ChiS is a noncanonical DNA-binding hybrid sensor kinase that directly regulates the chitin utilization program in Vibrio cholerae]( Catherine A. Klancher, Shouji Yamamoto, Triana N. Dalia, and Ankur B. Dalia [A Zika virus envelope mutation preceding the 2015 epidemic enhances virulence and fitness for transmission]( Chao Shan, Hongjie Xia, Sherry L. Haller, Sasha R. Azar, Yang Liu, Jianying Liu, Antonio E. Muruato, Rubing Chen, Shannan L. Rossi, Maki Wakamiya, Nikos Vasilakis, Rongjuan Pei, Camila R. Fontes-Garfias, Sanjay Kumar Singh, Xuping Xie, Scott C. Weaver, and Pei-Yong Shi [Haplotype networks of SARS-CoV-2 infections in the Diamond Princess cruise ship outbreak]( Tsuyoshi Sekizuka, Kentaro Itokawa, Tsutomu Kageyama, Shinji Saito, Ikuyo Takayama, Hideki Asanuma, Naganori Nao, Rina Tanaka, Masanori Hashino, Takuri Takahashi, Hajime Kamiya, Takuya Yamagishi, Kensaku Kakimoto, Motoi Suzuki, Hideki Hasegawa, Takaji Wakita, and Makoto Kuroda [Temporal encoding of bacterial identity and traits in growth dynamics]( Carolyn Zhang, Wenchen Song, Helena R. Ma, Xiao Peng, Deverick J. Anderson, Vance G. Fowler Jr, Joshua T. Thaden, Minfeng Xiao, and Lingchong You [Molecular biology and structure of a novel penaeid shrimp densovirus elucidate convergent parvoviral host capsid evolution]( Judit J. Pénzes, Hanh T. Pham, Paul Chipman, Nilakshee Bhattacharya, Robert McKenna, Mavis Agbandje-McKenna, and Peter Tijssen [Symbiosis between nanohaloarchaeon and haloarchaeon is based on utilization of different polysaccharides]( Violetta La Cono, Enzo Messina, Manfred Rohde, Erika Arcadi, Sergio Ciordia, Francesca Crisafi, Renata Denaro, Manuel Ferrer, Laura Giuliano, Peter N. Golyshin, Olga V. Golyshina, John E. Hallsworth, Gina La Spada, Maria C. Mena, Alexander Y. Merkel, Margarita A. Shevchenko, Francesco Smedile, Dimitry Y. Sorokin, Stepan V. Toshchakov, and Michail M. Yakimov [Small proteins regulate Salmonella survival inside macrophages by controlling degradation of a magnesium transporter]( Jinki Yeom, Yi Shao, and Eduardo A. Groisman Neuroscience [Heuristics and optimal solutions to the breadth–depth dilemma]( Rubén Moreno-Bote, Jorge Ramírez-Ruiz, Jan Drugowitsch, and Benjamin Y. Hayden [Geometric renormalization unravels self-similarity of the multiscale human connectome]( Muhua Zheng, Antoine Allard, Patric Hagmann, Yasser Alemán-Gómez, and M. Ángeles Serrano [Global enhancement of cortical excitability following coactivation of large neuronal populations]( Deng Zhang, Xingjian Yan, Liang She, Yunqing Wen, and Mu-ming Poo [Loss of Hap1 selectively promotes striatal degeneration in Huntington disease mice]( Qiong Liu, Siying Cheng, Huiming Yang, Louyin Zhu, Yongcheng Pan, Liang Jing, Beisha Tang, Shihua Li, and Xiao-Jiang Li [A temporal record of the past with a spectrum of time constants in the monkey entorhinal cortex]( Ian M. Bright, Miriam L. R. Meister, Nathanael A. Cruzado, Zoran Tiganj, Elizabeth A. Buffalo, and Marc W. Howard Pharmacology [Synthetic nanobodies as angiotensin receptor blockers]( Conor McMahon, Dean P. Staus, Laura M. Wingler, Jialu Wang, Meredith A. Skiba, Matthias Elgeti, Wayne L. Hubbell, Howard A. Rockman, Andrew C. Kruse, and Robert J. Lefkowitz Physiology [NFAT5, which protects against hypertonicity, is activated by that stress via structuring of its intrinsically disordered domain]( Raj Kumar, Jenna F. DuMond, Shagufta H. Khan, E. Brad Thompson, Yi He, Maurice B. Burg, and Joan D. Ferraris [A folding reaction at the C-terminal domain drives temperature sensing in TRPM8 channels]( Ignacio Díaz-Franulic, Natalia Raddatz, Karen Castillo, Fernando D. González-Nilo, and Ramon Latorre [Parkinson’s disease-related phosphorylation at Tyr39 rearranges α-synuclein amyloid fibril structure revealed by cryo-EM]( Kun Zhao, Yeh-Jun Lim, Zhenying Liu, Houfang Long, Yunpeng Sun, Jin-Jian Hu, Chunyu Zhao, Youqi Tao, Xing Zhang, Dan Li, Yan-Mei Li, and Cong Liu Plant Biology [The synthesis of xyloglucan, an abundant plant cell wall polysaccharide, requires CSLC function]( Sang-Jin Kim, Balakumaran Chandrasekar, Anne C. Rea, Linda Danhof, Starla Zemelis-Durfee, Nicholas Thrower, Zachary S. Shepard, Markus Pauly, Federica Brandizzi, and Kenneth Keegstra [Alternative splicing of DSP1 enhances snRNA accumulation by promoting transcription termination and recycle of the processing complex]( Weili Wang, Xuepiao Pu, Siyu Yang, Yujie Feng, Chan Lin, Mu Li, Xi Li, Huali Li, Chunmei Meng, Qingjun Xie, Bin Yu, and Yunfeng Liu --------------------------------------------------------------- Corrections [Correction for Song et al., Flat latitudinal diversity gradient caused by the Permian–Triassic mass extinction]( [Correction for MacDonald and Mordecai, Amazon deforestation drives malaria transmission, and malaria burden reduces forest clearing]( [Correction for Johansson et al., An open challenge to advance probabilistic forecasting for dengue epidemics]( --------------------------------------------------------------- SI Correction [Correction to Supporting Information for Fushimi et al., Evolution-inspired design of multicolored photoswitches from a single cyanobacteriochrome scaffold]( [Cover] --------------------------------------------------------------- This message was sent to {EMAIL}. 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