PNAS Table of Contents for January 14, 2020; Vol. 117, No. 2

[PNAS] [Artificial Intelligence](/cgi/adclick/?ad=54616&adclick=true&url=https%3A%2F%2Fwww.pnas.org%2Fpage%2Fmedia%2Fpodcasts%23Artificial)   [January 14, 2020; Vol. 117, No. 2]( ) This Week in PNAS [In This Issue]( --------------------------------------------------------------- Science and Culture [Science and Culture: How a conference focused on algorithms balances serious math with computational whimsy]( Stephen Ornes How science intersects with culture. --------------------------------------------------------------- QnAs [QnAs with H. Michael Shepard and Dennis J. Slamon]( Tinsley H. Davis --------------------------------------------------------------- Profile [Profile of James Peebles, Michel Mayor, and Didier Queloz: 2019 Nobel Laureates in Physics]( Neta A. Bahcall and Adam Burrows --------------------------------------------------------------- Commentaries [Wild chimpanzees scaffold youngsters’ learning in a high-tech community]( Andrew Whiten [Evolutionarily conserved peptides coordinate lunar phase and metabolism]( Kathleen Whitlock [Leaf-derived bacterial communities adapt to the local environment]( Charles Copeland and Paul Schulze-Lefert --------------------------------------------------------------- Letters [Mixed growth curve data do not suffice to fully characterize the dynamics of mixed cultures]( Eva Balsa-Canto, Javier Alonso-del-Real, and Amparo Querol [Reply to Balsa-Canto et al.: Growth models are applicable to growth data, not to stationary-phase data]( Yoav Ram, Uri Obolski, Marcus W. Feldman, Judith Berman, and Lilach Hadany [A consideration of within-host human cytomegalovirus genetic variation]( Jeffrey D. Jensen and Timothy F. Kowalik [Reply to Jensen and Kowalik: Consideration of mixed infections is central to understanding HCMV intrahost diversity]( Charlotte J. Houldcroft, Juliana Cudini, Richard A. Goldstein, and Judith Breuer --------------------------------------------------------------- Physical Sciences Applied Physical Sciences [Multielemental single–atom-thick A layers in nanolaminated V2(Sn, A) C (A = Fe, Co, Ni, Mn) for tailoring magnetic properties]( Youbing Li, Jun Lu, Mian Li, Keke Chang, Xianhu Zha, Yiming Zhang, Ke Chen, Per O. Å. Persson, Lars Hultman, Per Eklund, Shiyu Du, Joseph S. Francisco, Zhifang Chai, Zhengren Huang, and Qing Huang Biophysics and Computational Biology [Deterministic actin waves as generators of cell polarization cues]( Luiza Stankevicins, Nicolas Ecker, Emmanuel Terriac, Paolo Maiuri, Rouven Schoppmeyer, Pablo Vargas, Ana-Maria Lennon-Duménil, Matthieu Piel, Bin Qu, Markus Hoth, Karsten Kruse, and Franziska Lautenschläger [Multimodal transcriptional control of pattern formation in embryonic development]( Nicholas C. Lammers, Vahe Galstyan, Armando Reimer, Sean A. Medin, Chris H. Wiggins, and Hernan G. Garcia [Neurons differentiate magnitude and location of mechanical stimuli]( Benjamin M. Gaub, Krishna Chaitanya Kasuba, Emilie Mace, Tobias Strittmatter, Pawel R. Laskowski, Sydney A. Geissler, Andreas Hierlemann, Martin Fussenegger, Botond Roska, and Daniel J. Müller [Revisiting the tumorigenesis timeline with a data-driven generative model]( Kamel Lahouel, Laurent Younes, Ludmila Danilova, Francis M. Giardiello, Ralph H. Hruban, John Groopman, Kenneth W. Kinzler, Bert Vogelstein, Donald Geman, and Cristian Tomasetti [Switching sides—Reengineered primary charge separation in the bacterial photosynthetic reaction center]( Philip D. Laible, Deborah K. Hanson, James C. Buhrmaster, Gregory A. Tira, Kaitlyn M. Faries, Dewey Holten, and Christine Kirmaier [Hybrid histidine kinase activation by cyclic di-GMP–mediated domain liberation]( Badri N. Dubey, Elia Agustoni, Raphael Böhm, Andreas Kaczmarczyk, Francesca Mangia, Christoph von Arx, Urs Jenal, Sebastian Hiller, Iván Plaza-Menacho, and Tilman Schirmer Chemistry [Structure of the cytochrome aa3-600 heme-copper menaquinol oxidase bound to inhibitor HQNO shows TM0 is part of the quinol binding site]( Jingjing Xu, Ziqiao Ding, Bing Liu, Sophia M. Yi, Jiao Li, Zhengguang Zhang, Yuchen Liu, Jin Li, Liu Liu, Aiwu Zhou, Robert B. Gennis, and Jiapeng Zhu [Does repeat synthesis in materials chemistry obey a power law?]( Mayank Agrawal, Rebecca Han, Dinushka Herath, and David S. Sholl Earth, Atmospheric, and Planetary Sciences [A carbonate-rich lake solution to the phosphate problem of the origin of life]( Jonathan D. Toner and David C. Catling [Middle Holocene expansion of Pacific Deep Water into the Southern Ocean]( Torben Struve, David J. Wilson, Tina van de Flierdt, Naomi Pratt, and Kirsty C. Crocket Engineering [A rapid and label-free platform for virus capture and identification from clinical samples]( Yin-Ting Yeh, Kristen Gulino, YuHe Zhang, Aswathy Sabestien, Tsui-Wen Chou, Bin Zhou, Zhong Lin, Istvan Albert, Huaguang Lu, Venkataraman Swaminathan, Elodie Ghedin, and Mauricio Terrones [Shape-controlled single-crystal growth of InP at low temperatures down to 220 °C]( Mark Hettick, Hao Li, Der-Hsien Lien, Matthew Yeh, Tzu-Yi Yang, Matin Amani, Niharika Gupta, Daryl C. Chrzan, Yu-Lun Chueh, and Ali Javey [The frequency of cortical microstimulation shapes artificial touch]( Thierri Callier, Nathan W. Brantly, Attilio Caravelli, and Sliman J. Bensmaia Environmental Sciences [Hazard from Himalayan glacier lake outburst floods]( Georg Veh, Oliver Korup, and Ariane Walz [A portrait of wellbore leakage in northeastern British Columbia, Canada]( Joshua Wisen, Romain Chesnaux, John Werring, Gilles Wendling, Paul Baudron, and Florent Barbecot Physics [Quantifying the flux as the driving force for nonequilibrium dynamics and thermodynamics in non-Michaelis–Menten enzyme kinetics]( Qiong Liu and Jin Wang --------------------------------------------------------------- Social Sciences Economic Sciences [Sensitivity of self-reported noncognitive skills to survey administration conditions]( Yuanyuan Chen, Shuaizhang Feng, James J. Heckman, and Tim Kautz Psychological and Cognitive Sciences [Rhythmic swaying induced by sound in chimpanzees (Pan troglodytes)]( Yuko Hattori and Masaki Tomonaga [Sadness, but not all negative emotions, heightens addictive substance use]( Charles A. Dorison, Ke Wang, Vaughan W. Rees, Ichiro Kawachi, Keith M. M. Ericson, and Jennifer S. Lerner [Altruistic behaviors relieve physical pain]( Yilu Wang, Jianqiao Ge, Hanqi Zhang, Haixia Wang, and Xiaofei Xie [Reward does not facilitate visual perceptual learning until sleep occurs]( Masako Tamaki, Aaron V. Berard, Tyler Barnes-Diana, Jesse Siegel, Takeo Watanabe, and Yuka Sasaki --------------------------------------------------------------- Biological Sciences Anthropology [Teaching varies with task complexity in wild chimpanzees]( Stephanie Musgrave, Elizabeth Lonsdorf, David Morgan, Madison Prestipino, Laura Bernstein-Kurtycz, Roger Mundry, and Crickette Sanz Applied Biological Sciences [A rapid and label-free platform for virus capture and identification from clinical samples]( Yin-Ting Yeh, Kristen Gulino, YuHe Zhang, Aswathy Sabestien, Tsui-Wen Chou, Bin Zhou, Zhong Lin, Istvan Albert, Huaguang Lu, Venkataraman Swaminathan, Elodie Ghedin, and Mauricio Terrones Biochemistry [Structure of the cytochrome aa3-600 heme-copper menaquinol oxidase bound to inhibitor HQNO shows TM0 is part of the quinol binding site]( Jingjing Xu, Ziqiao Ding, Bing Liu, Sophia M. Yi, Jiao Li, Zhengguang Zhang, Yuchen Liu, Jin Li, Liu Liu, Aiwu Zhou, Robert B. Gennis, and Jiapeng Zhu [The proton electrochemical gradient induces a kinetic asymmetry in the symport cycle of LacY]( Xiaoxu Jiang, Natalia Ermolova, John Lim, Seo Woo Choi, and H. Ronald Kaback [Substrate selectivity by the exonuclease Rrp6p]( Armend Axhemi, Elizabeth V. Wasmuth, Christopher D. Lima, and Eckhard Jankowsky [Spatiotemporal regulation of NADP(H) phosphatase Nocturnin and its role in oxidative stress response]( Isara Laothamatas, Peng Gao, Anushka Wickramaratne, Carlo G. Quintanilla, Arianna Dino, Crystal A. Khan, Jen Liou, and Carla B. Green Biophysics and Computational Biology [Quantifying the flux as the driving force for nonequilibrium dynamics and thermodynamics in non-Michaelis–Menten enzyme kinetics]( Qiong Liu and Jin Wang [Hybrid histidine kinase activation by cyclic di-GMP–mediated domain liberation]( Badri N. Dubey, Elia Agustoni, Raphael Böhm, Andreas Kaczmarczyk, Francesca Mangia, Christoph von Arx, Urs Jenal, Sebastian Hiller, Iván Plaza-Menacho, and Tilman Schirmer [High-yield monolayer graphene grids for near-atomic resolution cryoelectron microscopy]( Yimo Han, Xiao Fan, Haozhe Wang, Fang Zhao, Christopher G. Tully, Jing Kong, Nan Yao, and Nieng Yan [Proteome-wide observation of the phenomenon of life on the edge of solubility]( Giulia Vecchi, Pietro Sormanni, Benedetta Mannini, Andrea Vandelli, Gian Gaetano Tartaglia, Christopher M. Dobson, F. Ulrich Hartl, and Michele Vendruscolo [The functionally relevant site for paxilline inhibition of BK channels]( Yu Zhou, Xiao-Ming Xia, and Christopher J. Lingle [Structure and regulation of human epithelial cell transforming 2 protein]( Mengran Chen, Han Pan, Lingfei Sun, Peng Shi, Yikan Zhang, Le Li, Yuxing Huang, Jianhui Chen, Peng Jiang, Xianyang Fang, Congying Wu, and Zhucheng Chen [Munc13-1 MUN domain and Munc18-1 cooperatively chaperone SNARE assembly through a tetrameric complex]( Tong Shu, Huaizhou Jin, James E. Rothman, and Yongli Zhang [Crystal structure of human LDB1 in complex with SSBP2]( Hongyang Wang, Juhyun Kim, Zhizhi Wang, Xiao-Xue Yan, Ann Dean, and Wenqing Xu [Structure of the cell-binding component of the Clostridium difficile binary toxin reveals a di-heptamer macromolecular assembly]( Xingjian Xu, Raquel Godoy-Ruiz, Kaylin A. Adipietro, Christopher Peralta, Danya Ben-Hail, Kristen M. Varney, Mary E. Cook, Braden M. Roth, Paul T. Wilder, Thomas Cleveland, Alexander Grishaev, Heather M. Neu, Sarah L. J. Michel, Wenbo Yu, Dorothy Beckett, Richard R. Rustandi, Catherine Lancaster, John W. Loughney, Adam Kristopeit, Sianny Christanti, Jessica W. Olson, Alexander D. MacKerell, Amedee des Georges, Edwin Pozharski, and David J. Weber [A general-purpose protein design framework based on mining sequence–structure relationships in known protein structures]( Jianfu Zhou, Alexandra E. Panaitiu, and Gevorg Grigoryan Cell Biology [Deterministic actin waves as generators of cell polarization cues]( Luiza Stankevicins, Nicolas Ecker, Emmanuel Terriac, Paolo Maiuri, Rouven Schoppmeyer, Pablo Vargas, Ana-Maria Lennon-Duménil, Matthieu Piel, Bin Qu, Markus Hoth, Karsten Kruse, and Franziska Lautenschläger [Direct visualization of degradation microcompartments at the ER membrane]( Sahradha Albert, Wojciech Wietrzynski, Chia-Wei Lee, Miroslava Schaffer, Florian Beck, Jan M. Schuller, Patrice A. Salomé, Jürgen M. Plitzko, Wolfgang Baumeister, and Benjamin D. Engel [Multivalent interaction of ESCO2 with the replication machinery is required for sister chromatid cohesion in vertebrates]( Dawn Bender, Eulália Maria Lima Da Silva, Jingrong Chen, Annelise Poss, Lauren Gawey, Zane Rulon, and Susannah Rankin Developmental Biology [Multimodal transcriptional control of pattern formation in embryonic development]( Nicholas C. Lammers, Vahe Galstyan, Armando Reimer, Sean A. Medin, Chris H. Wiggins, and Hernan G. Garcia [The formation of the thumb requires direct modulation of Gli3 transcription by Hoxa13]( Maria Félix Bastida, Rocío Pérez-Gómez, Anna Trofka, Jianjian Zhu, Alvaro Rada-Iglesias, Rushikesh Sheth, H. Scott Stadler, Susan Mackem, and Marian A. Ros [Corazonin signaling integrates energy homeostasis and lunar phase to regulate aspects of growth and sexual maturation in Platynereis]( Gabriele Andreatta, Caroline Broyart, Charline Borghgraef, Karim Vadiwala, Vitaly Kozin, Alessandra Polo, Andrea Bileck, Isabel Beets, Liliane Schoofs, Christopher Gerner, and Florian Raible Ecology [Biotic and anthropogenic forces rival climatic/abiotic factors in determining global plant population growth and fitness]( William F. Morris, Johan Ehrlén, Johan P. Dahlgren, Alexander K. Loomis, and Allison M. Louthan Genetics [Mouse genetics reveals Barttin as a genetic modifier of Joubert syndrome]( Simon A. Ramsbottom, Peter E. Thelwall, Katrina M. Wood, Gavin J. Clowry, Laura A. Devlin, Flora Silbermann, Helena L. Spiewak, Shirlee Shril, Elisa Molinari, Friedhelm Hildebrandt, Meral Gunay-Aygun, Sophie Saunier, Heather J. Cordell, John A. Sayer, and Colin G. Miles Immunology and Inflammation [Intratumoral injection of the seasonal flu shot converts immunologically cold tumors to hot and serves as an immunotherapy for cancer]( Jenna H. Newman, C. Brent Chesson, Nora L. Herzog, Praveen K. Bommareddy, Salvatore M. Aspromonte, Russell Pepe, Ricardo Estupinian, Mones M. Aboelatta, Stuti Buddhadev, Saeed Tarabichi, Michael Lee, Shengguo Li, Daniel J. Medina, Eileena F. Giurini, Kajal H. Gupta, Gabriel Guevara-Aleman, Marco Rossi, Christina Nowicki, Abdulkareem Abed, Josef W. Goldufsky, Joseph R. Broucek, Raquel E. Redondo, David Rotter, Sachin R. Jhawar, Shang-Jui Wang, Frederick J. Kohlhapp, Howard L. Kaufman, Paul G. Thomas, Vineet Gupta, Timothy M. Kuzel, Jochen Reiser, Joyce Paras, Michael P. Kane, Eric A. Singer, Jyoti Malhotra, Lisa K. Denzin, Derek B. Sant’Angelo, Arnold B. Rabson, Leonard Y. Lee, Ahmed Lasfar, John Langenfeld, Jason M. Schenkel, Mary Jo Fidler, Emily S. Ruiz, Amanda L. Marzo, Jai S. Rudra, Ann W. Silk, and Andrew Zloza Medical Sciences [CCR2 inhibition reduces tumor myeloid cells and unmasks a checkpoint inhibitor effect to slow progression of resistant murine gliomas]( Joseph A. Flores-Toro, Defang Luo, Adithya Gopinath, Matthew R. Sarkisian, James J. Campbell, Israel F. Charo, Rajinder Singh, Thomas J. Schall, Meenal Datta, Rakesh K. Jain, Duane A. Mitchell, and Jeffrey K. Harrison [The circadian clock protein REVERBα inhibits pulmonary fibrosis development]( Peter S. Cunningham, Peter Meijer, Alicja Nazgiewicz, Simon G. Anderson, Lee A. Borthwick, James Bagnall, Gareth B. Kitchen, Monika Lodyga, Nicola Begley, Rajamiyer V. Venkateswaran, Rajesh Shah, Paul F. Mercer, Hannah J. Durrington, Neil C. Henderson, Karen Piper-Hanley, Andrew J. Fisher, Rachel C. Chambers, David A. Bechtold, Julie E. Gibbs, Andrew S. Loudon, Martin K. Rutter, Boris Hinz, David W. Ray, and John F. Blaikley Microbiology [Successive passaging of a plant-associated microbiome reveals robust habitat and host genotype-dependent selection]( Norma M. Morella, Francis Cheng-Hsuan Weng, Pierre M. Joubert, C. Jessica E. Metcalf, Steven Lindow, and Britt Koskella [The Mycobacterium marinum ESX-1 system mediates phagosomal permeabilization and type I interferon production via separable mechanisms]( Julia Lienard, Esther Nobs, Victoria Lovins, Elin Movert, Christine Valfridsson, and Fredric Carlsson [Energy conservation involving 2 respiratory circuits]( Marie Charlotte Schoelmerich, Alexander Katsyv, Judith Dönig, Timothy J. Hackmann, and Volker Müller [Pyridoxal-5′-phosphate–dependent bifunctional enzyme catalyzed biosynthesis of indolizidine alkaloids in fungi]( Guang Zhi Dai, Wen Bo Han, Ya Ning Mei, Kuang Xu, Rui Hua Jiao, Hui Ming Ge, and Ren Xiang Tan [Rescue of tomato spotted wilt virus entirely from complementary DNA clones]( Mingfeng Feng, Ruixiang Cheng, Minglong Chen, Rong Guo, Luyao Li, Zhike Feng, Jianyan Wu, Li Xie, Jian Hong, Zhongkai Zhang, Richard Kormelink, and Xiaorong Tao Neuroscience [Neurons differentiate magnitude and location of mechanical stimuli]( Benjamin M. Gaub, Krishna Chaitanya Kasuba, Emilie Mace, Tobias Strittmatter, Pawel R. Laskowski, Sydney A. Geissler, Andreas Hierlemann, Martin Fussenegger, Botond Roska, and Daniel J. Müller [The frequency of cortical microstimulation shapes artificial touch]( Thierri Callier, Nathan W. Brantly, Attilio Caravelli, and Sliman J. Bensmaia [Variable functional connectivity architecture of the preterm human brain: Impact of developmental cortical expansion and maturation]( Sophia Stoecklein, Anne Hilgendorff, Meiling Li, Kai Förster, Andreas W. Flemmer, Franziska Galiè, Stephan Wunderlich, Danhong Wang, Sophie Stein, Harald Ehrhardt, Olaf Dietrich, Qihong Zou, Shuqin Zhou, Birgit Ertl-Wagner, and Hesheng Liu [Mechanistic insights into the interactions of dynein regulator Ndel1 with neuronal ankyrins and implications in polarity maintenance]( Jin Ye, Jianchao Li, Fei Ye, Yan Zhang, Mingjie Zhang, and Chao Wang Physiology [Behavioral evidence for geomagnetic imprinting and transgenerational inheritance in fruit flies]( In-Taek Oh, Hye-Jin Kwon, Soo-Chan Kim, Hyung-Jun Kim, Kenneth J. Lohmann, and Kwon-Seok Chae Plant Biology [Combinatorial interactions of the LEC1 transcription factor specify diverse developmental programs during soybean seed development]( Leonardo Jo, Julie M. Pelletier, Ssu-Wei Hsu, Russell Baden, Robert B. Goldberg, and John J. Harada --------------------------------------------------------------- Corrections [Correction for Yu et al., Wildfire prevention through prophylactic treatment of high-risk landscapes using viscoelastic retardant fluids]( [Correction for Zhang et al., Elevated signature of a gene module coexpressed with CDC20 marks genomic instability in glioma]( [Correction for Heeger and Mackey, Oscillatory recurrent gated neural integrator circuits (ORGaNICs), a unifying theoretical framework for neural dynamics]( [Cover] --------------------------------------------------------------- This message was sent to {EMAIL}. [Unsubscribe]( from or [edit]( your subscription for this service. Or by mail: Customer Service * 973 University Avenue * Los Gatos, CA 95032 * U.S.A. Copyright © 2020 by the National Academy of Sciences