PNAS Table of Contents for November 26, 2019; Vol. 116, No. 48

[PNAS] [Sustainability Portal](/cgi/adclick/?ad=54502&adclick=true&url=https%3A%2F%2Fwww.pnas.org%2Fportal%2Fsustainability)   [November 26, 2019; Vol. 116, No. 48]( ) This Week in PNAS [In This Issue]( --------------------------------------------------------------- News Feature [News Feature: Gene therapy successes point to better therapies]( Elie Dolgin An in-depth look at trending science issues. --------------------------------------------------------------- Commentaries [Understanding how people detect social class from speech requires taking a cultural psychological perspective]( Nicole M. Stephens and Sarah S. M. Townsend [Playing the long game wins the cohesion–adhesion rivalry]( Richard C. Remsing [Stress during pregnancy: Fetal males pay the price]( Margaret M. McCarthy [The DAGs of war]( David Fisman and Ashleigh Tuite --------------------------------------------------------------- Letters [The minimum mean paradox: A mechanical explanation for apparent experiment aversion]( Robert Mislavsky, Berkeley J. Dietvorst, and Uri Simonsohn [Reply to Mislavsky et al.: Sometimes people really are averse to experiments]( Michelle N. Meyer, Patrick R. Heck, Geoffrey S. Holtzman, Stephen M. Anderson, William Cai, Duncan J. Watts, and Christopher F. Chabris [Rainfall regulation of grazed grasslands]( Maowei Liang and Elise S. Gornish [Reply to Liang and Gornish: Climate and livestock grazing jointly regulate grassland ecosystem multifunctionality]( Ling Wang and Deli Wang --------------------------------------------------------------- Brief Report [WEE1 kinase inhibitor AZD1775 induces CDK1 kinase-dependent origin firing in unperturbed G1- and S-phase cells]( Tatiana N. Moiseeva, Chenao Qian, Norie Sugitani, Hatice U. Osmanbeyoglu, and Christopher J. Bakkenist --------------------------------------------------------------- Physical Sciences Applied Mathematics [On the energy efficiency of cell migration in diverse physical environments]( Yizeng Li, Lingxing Yao, Yoichiro Mori, and Sean X. Sun Applied Physical Sciences [A unified description of hydrophilic and superhydrophobic surfaces in terms of the wetting and drying transitions of liquids]( Robert Evans, Maria C. Stewart, and Nigel B. Wilding [Crack engineering for the construction of arbitrary hierarchical architectures]( Wanbo Li, Miao Yu, Jing Sun, Kentaro Mochizuki, Siyu Chen, Huanxi Zheng, Jiaqian Li, Shuhuai Yao, Hongkai Wu, Beng S. Ong, Satoshi Kawata, Zuankai Wang, and Kangning Ren Chemistry [Highly active oxygen evolution integrated with efficient CO2 to CO electroreduction]( Yongtao Meng, Xiao Zhang, Wei-Hsuan Hung, Junkai He, Yi-Sheng Tsai, Yun Kuang, Michael J. Kenney, Jing-Jong Shyue, Yijin Liu, Kevin H. Stone, Xueli Zheng, Steven L. Suib, Meng-Chang Lin, Yongye Liang, and Hongjie Dai [Real-time probing of chirality during a chemical reaction]( Denitsa Baykusheva, Daniel Zindel, Vít Svoboda, Elias Bommeli, Manuel Ochsner, Andres Tehlar, and Hans Jakob Wörner Computer Sciences [Quantification of the resilience of primary care networks by stress testing the health care system]( Donald Ruggiero Lo Sardo, Stefan Thurner, Johannes Sorger, Georg Duftschmid, Gottfried Endel, and Peter Klimek Earth, Atmospheric, and Planetary Sciences [Heightened levels and seasonal inversion of riverine suspended sediment in a tropical biodiversity hot spot due to artisanal gold mining]( Evan N. Dethier, Shannon L. Sartain, and David A. Lutz [Normalized US hurricane damage estimates using area of total destruction, 1900−2018]( Aslak Grinsted, Peter Ditlevsen, and Jens Hesselbjerg Christensen [Unraveling driving forces explaining significant reduction in satellite-inferred Arctic surface albedo since the 1980s]( Rudong Zhang, Hailong Wang, Qiang Fu, Philip J. Rasch, and Xuanji Wang Engineering [Solvent fluctuations in the solvation shell determine the activation barrier for crystal growth rates]( Anish V. Dighe and Meenesh R. Singh [Metamaterials with engineered failure load and stiffness]( Sai Sharan Injeti, Chiara Daraio, and Kaushik Bhattacharya [Shockley–Queisser triangle predicts the thermodynamic efficiency limits of arbitrarily complex multijunction bifacial solar cells]( Muhammad A. Alam and M. Ryyan Khan [Label-free visualization and characterization of extracellular vesicles in breast cancer]( Sixian You, Ronit Barkalifa, Eric J. Chaney, Haohua Tu, Jaena Park, Janet Elise Sorrells, Yi Sun, Yuan-Zhi Liu, Lin Yang, Danny Z. Chen, Marina Marjanovic, Saurabh Sinha, and Stephen A. Boppart Physics [Superlattice-induced ferroelectricity in charge-ordered La1/3Sr2/3FeO3]( Se Young Park, Karin M. Rabe, and Jeffrey B. Neaton [How collective asperity detachments nucleate slip at frictional interfaces]( Tom W. J. de Geus, Marko Popović, Wencheng Ji, Alberto Rosso, and Matthieu Wyart --------------------------------------------------------------- Social Sciences Economic Sciences [Normalized US hurricane damage estimates using area of total destruction, 1900−2018]( Aslak Grinsted, Peter Ditlevsen, and Jens Hesselbjerg Christensen Psychological and Cognitive Sciences [Pubertal stress recalibration reverses the effects of early life stress in postinstitutionalized children]( Megan R. Gunnar, Carrie E. DePasquale, Brie M. Reid, and Bonny Donzella [Veil-of-ignorance reasoning favors the greater good]( Karen Huang, Joshua D. Greene, and Max Bazerman [Maternal prenatal stress phenotypes associate with fetal neurodevelopment and birth outcomes]( Kate Walsh, Clare A. McCormack, Rachel Webster, Anita Pinto, Seonjoo Lee, Tianshu Feng, H. Sloan Krakovsky, Sinclaire M. O’Grady, Benjamin Tycko, Frances A. Champagne, Elizabeth A. Werner, Grace Liu, and Catherine Monk Social Sciences [Quantification of the resilience of primary care networks by stress testing the health care system]( Donald Ruggiero Lo Sardo, Stefan Thurner, Johannes Sorger, Georg Duftschmid, Gottfried Endel, and Peter Klimek --------------------------------------------------------------- Biological Sciences Anthropology [Association of EGLN1 gene with high aerobic capacity of Peruvian Quechua at high altitude]( Tom D. Brutsaert, Melisa Kiyamu, Gianpietro Elias Revollendo, Jenna L. Isherwood, Frank S. Lee, Maria Rivera-Ch, Fabiola Leon-Velarde, Sudipta Ghosh, and Abigail W. Bigham Applied Biological Sciences [Label-free visualization and characterization of extracellular vesicles in breast cancer]( Sixian You, Ronit Barkalifa, Eric J. Chaney, Haohua Tu, Jaena Park, Janet Elise Sorrells, Yi Sun, Yuan-Zhi Liu, Lin Yang, Danny Z. Chen, Marina Marjanovic, Saurabh Sinha, and Stephen A. Boppart [Fast fit-free analysis of fluorescence lifetime imaging via deep learning]( Jason T. Smith, Ruoyang Yao, Nattawut Sinsuebphon, Alena Rudkouskaya, Nathan Un, Joseph Mazurkiewicz, Margarida Barroso, Pingkun Yan, and Xavier Intes Biochemistry [Roles of singleton tryptophan motifs in COPI coat stability and vesicle tethering]( Sophie M. Travis, Bashkim Kokona, Robert Fairman, and Frederick M. Hughson [Probing the rice Rubisco–Rubisco activase interaction via subunit heterooligomerization]( Devendra Shivhare, Jediael Ng, Yi-Chin Candace Tsai, and Oliver Mueller-Cajar [Steric complementarity directs sequence promiscuous leader binding in RiPP biosynthesis]( Jonathan R. Chekan, Chayanid Ongpipattanakul, and Satish K. Nair [Structural studies of the eIF4E–VPg complex reveal a direct competition for capped RNA: Implications for translation]( Luciana Coutinho de Oliveira, Laurent Volpon, Amanda K. Rahardjo, Michael J. Osborne, Biljana Culjkovic-Kraljacic, Christian Trahan, Marlene Oeffinger, Benjamin H. Kwok, and Katherine L. B. Borden Biophysics and Computational Biology [Intrinsic elasticity of nucleosomes is encoded by histone variants and calibrated by their binding partners]( Daniël P. Melters, Mary Pitman, Tatini Rakshit, Emilios K. Dimitriadis, Minh Bui, Garegin A. Papoian, and Yamini Dalal [mRNA structure regulates protein expression through changes in functional half-life]( David M. Mauger, B. Joseph Cabral, Vladimir Presnyak, Stephen V. Su, David W. Reid, Brooke Goodman, Kristian Link, Nikhil Khatwani, John Reynders, Melissa J. Moore, and Iain J. McFadyen Cell Biology [T6SS and ExoA of flesh-eating Aeromonas hydrophila in peritonitis and necrotizing fasciitis during mono- and polymicrobial infections]( Ana Fernández-Bravo, Paul B. Kilgore, Jourdan A. Andersson, Elizabeth Blears, Maria José Figueras, Nur A. Hasan, Rita R. Colwell, Jian Sha, and Ashok K. Chopra [RAMP3 determines rapid recycling of atypical chemokine receptor-3 for guided angiogenesis]( Duncan I. Mackie, Natalie R. Nielsen, Matthew Harris, Smriti Singh, Reema B. Davis, Danica Dy, Graham Ladds, and Kathleen M. Caron [Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration]( Andrew P. Voigt, Kelly Mulfaul, Nathaniel K. Mullin, Miles J. Flamme-Wiese, Joseph C. Giacalone, Edwin M. Stone, Budd A. Tucker, Todd E. Scheetz, and Robert F. Mullins [aPKCi triggers basal extrusion of luminal mammary epithelial cells by tuning contractility and vinculin localization at cell junctions]( Clémentine Villeneuve, Emilie Lagoutte, Ludmilla de Plater, Samuel Mathieu, Jean-Baptiste Manneville, Jean-Léon Maître, Philippe Chavrier, and Carine Rossé Developmental Biology [Early sarcomere and metabolic defects in a zebrafish pitx2c cardiac arrhythmia model]( Michelle M. Collins, Gustav Ahlberg, Camilla Vestergaard Hansen, Stefan Guenther, Rubén Marín-Juez, Anna M. Sokol, Hadil El-Sammak, Janett Piesker, Ylva Hellsten, Morten S. Olesen, Didier Y. R. Stainier, and Pia R. Lundegaard [Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain]( Zhongqiu Li, Yanxin Li, and Jianwei Jiao [Hepatocyte nuclear factor-1β regulates Wnt signaling through genome-wide competition with β-catenin/lymphoid enhancer binding factor]( Siu Chiu Chan, Ying Zhang, Marco Pontoglio, and Peter Igarashi Ecology [Heightened levels and seasonal inversion of riverine suspended sediment in a tropical biodiversity hot spot due to artisanal gold mining]( Evan N. Dethier, Shannon L. Sartain, and David A. Lutz [Prey-size plastics are invading larval fish nurseries]( Jamison M. Gove, Jonathan L. Whitney, Margaret A. McManus, Joey Lecky, Felipe C. Carvalho, Jennifer M. Lynch, Jiwei Li, Philipp Neubauer, Katharine A. Smith, Jana E. Phipps, Donald R. Kobayashi, Karla B. Balagso, Emily A. Contreras, Mark E. Manuel, Mark A. Merrifield, Jeffrey J. Polovina, Gregory P. Asner, Jeffrey A. Maynard, and Gareth J. Williams Evolution [Introgression drives repeated evolution of winter coat color polymorphism in hares]( Iwona Giska, Liliana Farelo, João Pimenta, Fernando A. Seixas, Mafalda S. Ferreira, João P. Marques, Inês Miranda, Jérôme Letty, Hannes Jenny, Klaus Hackländer, Eyðfinn Magnussen, and José Melo-Ferreira [Sexually antagonistic selection promotes genetic divergence between males and females in an ant]( Pierre-André Eyer, Alexander J. Blumenfeld, and Edward L. Vargo [Hidden resources in the Escherichia coli genome restore PLP synthesis and robust growth after deletion of the essential gene pdxB]( Juhan Kim, Jake J. Flood, Michael R. Kristofich, Cyrus Gidfar, Andrew B. Morgenthaler, Tobias Fuhrer, Uwe Sauer, Daniel Snyder, Vaughn S. Cooper, Christopher C. Ebmeier, William M. Old, and Shelley D. Copley [Parallel evolution of ancient, pleiotropic enhancers underlies butterfly wing pattern mimicry]( James J. Lewis, Rachel C. Geltman, Patrick C. Pollak, Kathleen E. Rondem, Steven M. Van Belleghem, Melissa J. Hubisz, Paul R. Munn, Linlin Zhang, Caleb Benson, Anyi Mazo-Vargas, Charles G. Danko, Brian A. Counterman, Riccardo Papa, and Robert D. Reed Genetics [A set of microRNAs coordinately controls tumorigenesis, invasion, and metastasis]( Iacovos P. Michael, Sadegh Saghafinia, and Douglas Hanahan [Genomic sites hypersensitive to ultraviolet radiation]( Sanjay Premi, Lynn Han, Sameet Mehta, James Knight, Dejian Zhao, Meg A. Palmatier, Karl Kornacker, and Douglas E. Brash [Definitive demonstration by synthesis of genome annotation completeness]( Paul R. Jaschke, Gabrielle A. Dotson, Kay S. Hung, Diane Liu, and Drew Endy Immunology and Inflammation [CRIg plays an essential role in intravascular clearance of bloodborne parasites by interacting with complement]( Gongguan Liu, Yong Fu, Mohammed Yosri, Yanli Chen, Peng Sun, Jinjun Xu, Mingshun Zhang, Donglei Sun, Ashley B. Strickland, Zachary B. Mackey, and Meiqing Shi [Neutrophils promote VLA-4–dependent B cell antigen presentation and accumulation within the meninges during neuroinflammation]( Chelsea R. Parker Harp, Angela S. Archambault, Matthew Cheung, Jesse W. Williams, Rafael S. Czepielewski, Patrick C. Duncker, Aaron J. Kilgore, Aidan T. Miller, Benjamin M. Segal, Alfred H. J. Kim, Gwendalyn J. Randolph, and Gregory F. Wu [Trisomy 21 dysregulates T cell lineages toward an autoimmunity-prone state associated with interferon hyperactivity]( Paula Araya, Katherine A. Waugh, Kelly D. Sullivan, Nicolás G. Núñez, Emiliano Roselli, Keith P. Smith, Ross E. Granrath, Angela L. Rachubinski, Belinda Enriquez Estrada, Eric T. Butcher, Ross Minter, Kathryn D. Tuttle, Tullia C. Bruno, Mariana Maccioni, and Joaquín M. Espinosa [Single-cell transcriptomics reveals expansion of cytotoxic CD4 T cells in supercentenarians]( Kosuke Hashimoto, Tsukasa Kouno, Tomokatsu Ikawa, Norihito Hayatsu, Yurina Miyajima, Haruka Yabukami, Tommy Terooatea, Takashi Sasaki, Takahiro Suzuki, Matthew Valentine, Giovanni Pascarella, Yasushi Okazaki, Harukazu Suzuki, Jay W. Shin, Aki Minoda, Ichiro Taniuchi, Hideyuki Okano, Yasumichi Arai, Nobuyoshi Hirose, and Piero Carninci Medical Sciences [Dysregulation of different classes of tRNA fragments in chronic lymphocytic leukemia]( Dario Veneziano, Luisa Tomasello, Veronica Balatti, Alexey Palamarchuk, Laura Z. Rassenti, Thomas J. Kipps, Yuri Pekarsky, and Carlo M. Croce [Mutant p53 antagonizes p63/p73-mediated tumor suppression via Notch1]( Jin Zhang, Wenqiang Sun, Xiangmudong Kong, Yanhong Zhang, Hee Jung Yang, Cong Ren, Yuqian Jiang, Mingyi Chen, and Xinbin Chen [An open challenge to advance probabilistic forecasting for dengue epidemics]( Michael A. Johansson, Karyn M. Apfeldorf, Scott Dobson, Jason Devita, Anna L. Buczak, Benjamin Baugher, Linda J. Moniz, Thomas Bagley, Steven M. Babin, Erhan Guven, Teresa K. Yamana, Jeffrey Shaman, Terry Moschou, Nick Lothian, Aaron Lane, Grant Osborne, Gao Jiang, Logan C. Brooks, David C. Farrow, Sangwon Hyun, Ryan J. Tibshirani, Roni Rosenfeld, Justin Lessler, Nicholas G. Reich, Derek A. T. Cummings, Stephen A. Lauer, Sean M. Moore, Hannah E. Clapham, Rachel Lowe, Trevor C. Bailey, Markel García-Díez, Marilia Sá Carvalho, Xavier Rodó, Tridip Sardar, Richard Paul, Evan L. Ray, Krzysztof Sakrejda, Alexandria C. Brown, Xi Meng, Osonde Osoba, Raffaele Vardavas, David Manheim, Melinda Moore, Dhananjai M. Rao, Travis C. Porco, Sarah Ackley, Fengchen Liu, Lee Worden, Matteo Convertino, Yang Liu, Abraham Reddy, Eloy Ortiz, Jorge Rivero, Humberto Brito, Alicia Juarrero, Leah R. Johnson, Robert B. Gram acy, Jeremy M. Cohen, Erin A. Mordecai, Courtney C. Murdock, Jason R. Rohr, Sadie J. Ryan, Anna M. Stewart-Ibarra, Daniel P. Weikel, Antarpreet Jutla, Rakibul Khan, Marissa Poultney, Rita R. Colwell, Brenda Rivera-García, Christopher M. Barker, Jesse E. Bell, Matthew Biggerstaff, David Swerdlow, Luis Mier-y-Teran-Romero, Brett M. Forshey, Juli Trtanj, Jason Asher, Matt Clay, Harold S. Margolis, Andrew M. Hebbeler, Dylan George, and Jean-Paul Chretien [Long-term in vivo microscopy of CAR T cell dynamics during eradication of CNS lymphoma in mice]( Matthias Mulazzani, Simon P. Fräßle, Iven von Mücke-Heim, Sigrid Langer, Xiaolan Zhou, Hellen Ishikawa-Ankerhold, Justin Leube, Wenlong Zhang, Sarah Dötsch, Mortimer Svec, Martina Rudelius, Martin Dreyling, Michael von Bergwelt-Baildon, Andreas Straube, Veit R. Buchholz, Dirk H. Busch, and Louisa von Baumgarten Microbiology [Colorectal cancer-associated microbiota contributes to oncogenic epigenetic signatures]( Iradj Sobhani, Emma Bergsten, Séverine Couffin, Aurélien Amiot, Biba Nebbad, Caroline Barau, Nicola de’Angelis, Sylvie Rabot, Florence Canoui-Poitrine, Denis Mestivier, Thierry Pédron, Khashayarsha Khazaie, and Philippe J. Sansonetti [A DNA virus-encoded immune antagonist fully masks the potent antiviral activity of RNAi in Drosophila]( Alfred W. Bronkhorst, Rob Vogels, Gijs J. Overheul, Bas Pennings, Valérie Gausson-Dorey, Pascal Miesen, and Ronald P. van Rij [Structure of the zinc-finger antiviral protein in complex with RNA reveals a mechanism for selective targeting of CG-rich viral sequences]( Jennifer L. Meagher, Matthew Takata, Daniel Gonçalves-Carneiro, Sarah C. Keane, Antoine Rebendenne, Heley Ong, Victoria K. Orr, Margaret R. MacDonald, Jeanne A. Stuckey, Paul D. Bieniasz, and Janet L. Smith Neuroscience [Hsp110 mitigates α-synuclein pathology in vivo]( Yumiko V. Taguchi, Erica L. Gorenberg, Maria Nagy, Drake Thrasher, Wayne A. Fenton, Laura Volpicelli-Daley, Arthur L. Horwich, and Sreeganga S. Chandra [Elovanoids counteract oligomeric β-amyloid-induced gene expression and protect photoreceptors]( Khanh V. Do, Marie-Audrey I. Kautzmann, Bokkyoo Jun, William C. Gordon, Robert Nshimiyimana, Rong Yang, Nicos A. Petasis, and Nicolas G. Bazan [Multistable properties of human subthalamic nucleus neurons in Parkinson’s disease]( Jeremy W. Chopek, Hans Hultborn, and Robert M. Brownstone [Accelerated evolution of oligodendrocytes in the human brain]( Stefano Berto, Isabel Mendizabal, Noriyoshi Usui, Kazuya Toriumi, Paramita Chatterjee, Connor Douglas, Carol A. Tamminga, Todd M. Preuss, Soojin V. Yi, and Genevieve Konopka [Hippocampal theta codes for distances in semantic and temporal spaces]( Ethan A. Solomon, Bradley C. Lega, Michael R. Sperling, and Michael J. Kahana Pharmacology [Distinct effects of orexin receptor antagonist and GABAA agonist on sleep and physical/cognitive functions after forced awakening]( Jaehoon Seol, Yuya Fujii, Insung Park, Yoko Suzuki, Fusae Kawana, Katsuhiko Yajima, Shoji Fukusumi, Tomohiro Okura, Makoto Satoh, Kumpei Tokuyama, Toshio Kokubo, and Masashi Yanagisawa Physiology [Pubertal stress recalibration reverses the effects of early life stress in postinstitutionalized children]( Megan R. Gunnar, Carrie E. DePasquale, Brie M. Reid, and Bonny Donzella [Oxidation of methionine residues activates the high-threshold heat-sensitive ion channel TRPV2]( Tabea C. Fricke, Frank Echtermeyer, Johannes Zielke, Jeanne de la Roche, Milos R. Filipovic, Stéphane Claverol, Christine Herzog, Makoto Tominaga, Ruth A. Pumroy, Vera Y. Moiseenkova-Bell, Peter M. Zygmunt, Andreas Leffler, and Mirjam J. Eberhardt Population Biology [The exacerbation of Ebola outbreaks by conflict in the Democratic Republic of the Congo]( Chad R. Wells, Abhishek Pandey, Martial L. Ndeffo Mbah, Bernard-A. Gaüzère, Denis Malvy, Burton H. Singer, and Alison P. Galvani --------------------------------------------------------------- Corrections [Correction for Zhou et al., Polar molecules catalyze CO insertion into metal-alkyl bonds through the displacement of an agostic C-H bond]( [Correction for Kolitsida et al., Phosphorylation of mitochondrial matrix proteins regulates their selective mitophagic degradation]( [Correction for Reimers et al., Identification of a cono-RFamide from the venom of Conus textile that targets ASIC3 and enhances muscle pain]( --------------------------------------------------------------- SI Correction [Correction to Supporting Information for Lee et al., Cell-type–specific transcriptome and histone modification dynamics during cellular reprogramming in the Arabidopsis stomatal lineage]( [Cover] --------------------------------------------------------------- This message was sent to {EMAIL}. 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