[PNAS]
[Cozzarelli Prize Nominations](/cgi/adclick/?ad=54374&adclick=true&url=https%3A%2F%2Fwww.pnas.org%2Fpage%2Fabout%2Fcozzarelli-prize)
 [October 8, 2019; Vol. 116, No. 41](
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This Week in PNAS
[In This Issue](
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News Feature
[News Feature: Fighting a fungal scourge](
Amy McDermott
An in-depth look at trending science issues.
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QnAs
[QnAs with Günter P. Wagner](
Sandeep Ravindran
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Commentaries
[The beginning of an era of functional genomics in Rickettsiology is steeped in history](
Ulrike G. Munderloh
[Nucleosomes remember where they were](
Steven Henikoff and Kami Ahmad
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Letters
[Reply to Head-Gordon and Paesani: Liquid water, a branched polymer with ∼100-fs short-lived heterogeneous hydrogen bonds](
Saber Naserifar and William A. Goddard III
[More data needed for claims about the earliest Oldowan artifacts](
Yonatan Sahle and Tegenu Gossa
[Reply to Sahle and Gossa: Technology and geochronology at the earliest known Oldowan site at Ledi-Geraru, Ethiopia](
David R. Braun, Vera Aldeias, Will Archer, J. Ramon Arrowsmith, Niguss Baraki, Christopher J. Campisano, Alan L. Deino, Erin N. DiMaggio, Guillaume Dupont-Nivet, Blade Engda, David A. Feary, Dominique I. Garello, Zenash Kerfelew, Shannon P. McPherron, David B. Patterson, Jonathan S. Reeves, Jessica C. Thompson, and Kaye E. Reed
[Breathing drives CSF: Impact on spaceflight disease and hydrocephalus](
Hans-Christoph Ludwig, Jens Frahm, Jutta Gärtner, and Steffi Dreha-Kulaczewski
[Reply to Ludwig et al.: A potential mechanism for intracranial cerebrospinal fluid accumulation during long-duration spaceflight](
Peter zu Eulenburg, Angelique Van Ombergen, Elena Tomilovskaya, and Floris L. Wuyts
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Physical Sciences
Applied Physical Sciences
[Observation of Rydberg exciton polaritons and their condensate in a perovskite cavity](
Wei Bao, Xiaoze Liu, Fei Xue, Fan Zheng, Renjie Tao, Siqi Wang, Yang Xia, Mervin Zhao, Jeongmin Kim, Sui Yang, Quanwei Li, Ying Wang, Yuan Wang, Lin-Wang Wang, Allan H. MacDonald, and Xiang Zhang
[Epsilon iron as a spin-smectic state](
Blair W. Lebert, Tommaso Gorni, Michele Casula, Stefan Klotz, François Baudelet, James M. Ablett, Thomas C. Hansen, Amélie Juhin, Alain Polian, Pascal Munsch, Gilles Le Marchand, Zailan Zhang, Jean-Pascal Rueff, and Matteo d’Astuto
[Propinquity drives the emergence of network structure and density](
Lazaros K. Gallos, Shlomo Havlin, H. Eugene Stanley, and Nina H. Fefferman
Biophysics and Computational Biology
[Optimal compressed sensing strategies for an array of nonlinear olfactory receptor neurons with and without spontaneous activity](
Shanshan Qin, Qianyi Li, Chao Tang, and Yuhai Tu
[Crystal growth kinetics as an architectural constraint on the evolution of molluscan shells](
Vanessa Schoeppler, Robert Lemanis, Elke Reich, Tamás Pusztai, László Gránásy, and Igor Zlotnikov
[Cell division rates decrease with age, providing a potential explanation for the age-dependent deceleration in cancer incidence](
Cristian Tomasetti, Justin Poling, Nicholas J. Roberts, Nyall R. London Jr., Meredith E. Pittman, Michael C. Haffner, Anthony Rizzo, Alex Baras, Baktiar Karim, Antonio Kim, Christopher M. Heaphy, Alan K. Meeker, Ralph H. Hruban, Christine A. Iacobuzio-Donahue, and Bert Vogelstein
[RNA polymerases as moving barriers to condensin loop extrusion](
Hugo B. Brandão, Payel Paul, Aafke A. van den Berg, David Z. Rudner, Xindan Wang, and Leonid A. Mirny
Chemistry
[A self-assembled Ru–Pt metallacage as a lysosome-targeting photosensitizer for 2-photon photodynamic therapy](
Zhixuan Zhou, Jiangping Liu, Juanjuan Huang, Thomas W. Rees, Yiliang Wang, Heng Wang, Xiaopeng Li, Hui Chao, and Peter J. Stang
[Excited-state proton transfer relieves antiaromaticity in molecules](
Chia-Hua Wu, Lucas José Karas, Henrik Ottosson, and Judy I-Chia Wu
[Selective cadmium regulation mediated by a cooperative binding mechanism in CadR](
Xichun Liu, Qingyuan Hu, Jinmei Yang, Shanqing Huang, Tianbiao Wei, Weizhong Chen, Yafeng He, Dan Wang, Zhijun Liu, Kang Wang, Jianhua Gan, and Hao Chen
[Early detection and monitoring of cerebral ischemia using calcium-responsive MRI probes](
Tanja Savić, Giuseppe Gambino, Vahid S. Bokharaie, Hamid R. Noori, Nikos K. Logothetis, and Goran Angelovski
Earth, Atmospheric, and Planetary Sciences
[Factors driving the seasonal and hourly variability of sea-spray aerosol number in the North Atlantic](
Georges Saliba, Chia-Li Chen, Savannah Lewis, Lynn M. Russell, Laura-Helena Rivellini, Alex K. Y. Lee, Patricia K. Quinn, Timothy S. Bates, Nils Haëntjens, Emmanuel S. Boss, Lee Karp-Boss, Nicholas Baetge, Craig A. Carlson, and Michael J. Behrenfeld
[Ca isotopes record rapid crystal growth in volcanic and subvolcanic systems](
Michael A. Antonelli, Tushar Mittal, Anders McCarthy, Barbara Tripoli, James M. Watkins, and Donald J. DePaolo
Physics
[Raman interrogation of the ferroelectric phase transition in polar metal LiOsO3](
Feng Jin, Le Wang, Anmin Zhang, Jianting Ji, Youguo Shi, Xiaoqun Wang, Rong Yu, Jiandi Zhang, E. W. Plummer, and Qingming Zhang
[Generation and detection of spin-orbit coupled neutron beams](
Dusan Sarenac, Connor Kapahi, Wangchun Chen, Charles W. Clark, David G. Cory, Michael G. Huber, Ivar Taminiau, Kirill Zhernenkov, and Dmitry A. Pushin
[Magnetic field-driven quantum criticality in antiferromagnetic CePtIn4](
Debarchan Das, Daniel Gnida, Piotr Wiśniewski, and Dariusz Kaczorowski
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Social Sciences
Economic Sciences
[Predicting kidney transplant outcomes with partial knowledge of HLA mismatch](
Charles F. Manski, Anat R. Tambur, and Michael Gmeiner
Psychological and Cognitive Sciences
[Task-based fMRI predicts response and remission to exposure therapy in obsessive-compulsive disorder](
David Pagliaccio, Rachel Middleton, Dianne Hezel, Shari Steinman, Ivar Snorrason, Marina Gershkovich, Raphael Campeas, Anthony Pinto, Page Van Meter, H. Blair Simpson, and Rachel Marsh
[Generics designate kinds but not always essences](
Alexander Noyes and Frank C. Keil
Social Sciences
[Propinquity drives the emergence of network structure and density](
Lazaros K. Gallos, Shlomo Havlin, H. Eugene Stanley, and Nina H. Fefferman
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Biological Sciences
Applied Biological Sciences
[Highly efficient DSB-free base editing for streptomycetes with CRISPR-BEST](
Yaojun Tong, Christopher M. Whitford, Helene L. Robertsen, Kai Blin, Tue S. Jørgensen, Andreas K. Klitgaard, Tetiana Gren, Xinglin Jiang, Tilmann Weber, and Sang Yup Lee
[The making of natural iron sulfide nanoparticles in a hot vent snail](
Satoshi Okada, Chong Chen, Tomo-o Watsuji, Manabu Nishizawa, Yohey Suzuki, Yuji Sano, Dass Bissessur, Shigeru Deguchi, and Ken Takai
[Cryptic diversity of a widespread global pathogen reveals expanded threats to amphibian conservation](
Allison Q. Byrne, Vance T. Vredenburg, An Martel, Frank Pasmans, Rayna C. Bell, David C. Blackburn, Molly C. Bletz, Jaime Bosch, Cheryl J. Briggs, Rafe M. Brown, Alessandro Catenazzi, Mariel Familiar López, Raul Figueroa-Valenzuela, Sonia L. Ghose, Jef R. Jaeger, Andrea J. Jani, Miloslav Jirku, Roland A. Knapp, Antonio Muñoz, Daniel M. Portik, Corinne L. Richards-Zawacki, Heidi Rockney, Sean M. Rovito, Tariq Stark, Hasan Sulaeman, Nguyen Thien Tao, Jamie Voyles, Anthony W. Waddle, Zhiyong Yuan, and Erica Bree Rosenblum
Biochemistry
[Crystal growth kinetics as an architectural constraint on the evolution of molluscan shells](
Vanessa Schoeppler, Robert Lemanis, Elke Reich, Tamás Pusztai, László Gránásy, and Igor Zlotnikov
[Selective cadmium regulation mediated by a cooperative binding mechanism in CadR](
Xichun Liu, Qingyuan Hu, Jinmei Yang, Shanqing Huang, Tianbiao Wei, Weizhong Chen, Yafeng He, Dan Wang, Zhijun Liu, Kang Wang, Jianhua Gan, and Hao Chen
[The structure of the colorectal cancer-associated enzyme GalNAc-T12 reveals how nonconserved residues dictate its function](
Amy J. Fernandez, Earnest James Paul Daniel, Sai Pooja Mahajan, Jeffrey J. Gray, Thomas A. Gerken, Lawrence A. Tabak, and Nadine L. Samara
[Intragenomic variability and extended sequence patterns in the mutational signature of ultraviolet light](
Markus Lindberg, Martin Boström, Kerryn Elliott, and Erik Larsson
[Unusual dynamics of the divergent malaria parasite PfAct1 actin filament](
Hailong Lu, Patricia M. Fagnant, and Kathleen M. Trybus
[Fibulin-4 exerts a dual role in LTBP-4L–mediated matrix assembly and function](
Heena Kumra, Valentin Nelea, Hana Hakami, Amelie Pagliuzza, Jelena Djokic, Jiongci Xu, Hiromi Yanagisawa, and Dieter P. Reinhardt
Biophysics and Computational Biology
[Single-molecule localization microscopy as nonlinear inverse problem](
Ji Yu and Ahmed Elmokadem
[Generation of the configurational ensemble of an intrinsically disordered protein from unbiased molecular dynamics simulation](
Utsab R. Shrestha, Puneet Juneja, Qiu Zhang, Viswanathan Gurumoorthy, Jose M. Borreguero, Volker Urban, Xiaolin Cheng, Sai Venkatesh Pingali, Jeremy C. Smith, Hugh M. O’Neill, and Loukas Petridis
[DDX5 helicase resolves G-quadruplex and is involved in MYC gene transcriptional activation](
Guanhui Wu, Zheng Xing, Elizabeth J. Tran, and Danzhou Yang
[Transferrin receptor binds virus capsid with dynamic motion](
Hyunwook Lee, Heather M. Callaway, Javier O. Cifuente, Carol M. Bator, Colin R. Parrish, and Susan L. Hafenstein
[SDS22 selectively recognizes and traps metal-deficient inactive PP1](
Meng S. Choy, Thomas M. Moon, Rini Ravindran, Johnny A. Bray, Lucy C. Robinson, Tara L. Archuleta, Wuxian Shi, Wolfgang Peti, Kelly Tatchell, and Rebecca Page
Cell Biology
[Cell division rates decrease with age, providing a potential explanation for the age-dependent deceleration in cancer incidence](
Cristian Tomasetti, Justin Poling, Nicholas J. Roberts, Nyall R. London Jr., Meredith E. Pittman, Michael C. Haffner, Anthony Rizzo, Alex Baras, Baktiar Karim, Antonio Kim, Christopher M. Heaphy, Alan K. Meeker, Ralph H. Hruban, Christine A. Iacobuzio-Donahue, and Bert Vogelstein
[RNA polymerases as moving barriers to condensin loop extrusion](
Hugo B. Brandão, Payel Paul, Aafke A. van den Berg, David Z. Rudner, Xindan Wang, and Leonid A. Mirny
[Mast cells are critical for controlling the bacterial burden and the healing of infected wounds](
C. Zimmermann, D. Troeltzsch, V. A. Giménez-Rivera, S. J. Galli, M. Metz, M. Maurer, and F. Siebenhaar
[Phosphorylation of DEPDC5, a component of the GATOR1 complex, releases inhibition of mTORC1 and promotes tumor growth](
Sathish K. R. Padi, Neha Singh, Jeremiah J. Bearss, Virginie Olive, Jin H. Song, Marina Cardó-Vila, Andrew S. Kraft, and Koichi Okumura
[CRIF1 as a potential target to improve the radiosensitivity of osteosarcoma](
Qian Ran, Feng Jin, Yang Xiang, Lixin Xiang, Qiushi Wang, Fengjie Li, Li Chen, Yuan Zhang, Chun Wu, Luping Zhou, Yanni Xiao, Lili Chen, Jiang Wu, Jiang F. Zhong, Shengwen Calvin Li, and Zhongjun Li
[Phosphorylation of mitochondrial matrix proteins regulates their selective mitophagic degradation](
Panagiota Kolitsida, Jianwen Zhou, Michal Rackiewicz, Vladimir Nolic, Jörn Dengjel, and Hagai Abeliovich
[The FBXW2–MSX2–SOX2 axis regulates stem cell property and drug resistance of cancer cells](
Yuan Yin, Chuan-Ming Xie, Hua Li, Mingjia Tan, Guoan Chen, Rachel Schiff, Xiufang Xiong, and Yi Sun
Developmental Biology
[Dronc-independent basal executioner caspase activity sustains Drosophila imaginal tissue growth](
Natsuki Shinoda, Nozomi Hanawa, Takahiro Chihara, Akiko Koto, and Masayuki Miura
[Transcriptional control of lung alveolar type 1 cell development and maintenance by NK homeobox 2-1](
Danielle R. Little, Kamryn N. Gerner-Mauro, Per Flodby, Edward D. Crandall, Zea Borok, Haruhiko Akiyama, Shioko Kimura, Edwin J. Ostrin, and Jichao Chen
Ecology
[Individual and collective encoding of risk in animal groups](
Matthew M. G. Sosna, Colin R. Twomey, Joseph Bak-Coleman, Winnie Poel, Bryan C. Daniels, Pawel Romanczuk, and Iain D. Couzin
Environmental Sciences
[Variable impacts of contemporary versus legacy agricultural phosphorus on US river water quality](
Sarah M. Stackpoole, Edward G. Stets, and Lori A. Sprague
[A marine plasmid hitchhiking vast phylogenetic and geographic distances](
Jörn Petersen, John Vollmers, Victoria Ringel, Henner Brinkmann, Claire Ellebrandt-Sperling, Cathrin Spröer, Alexandra M. Howat, J. Colin Murrell, and Anne-Kristin Kaster
[A distinct lineage of giant viruses brings a rhodopsin photosystem to unicellular marine predators](
David M. Needham, Susumu Yoshizawa, Toshiaki Hosaka, Camille Poirier, Chang Jae Choi, Elisabeth Hehenberger, Nicholas A. T. Irwin, Susanne Wilken, Cheuk-Man Yung, Charles Bachy, Rika Kurihara, Yu Nakajima, Keiichi Kojima, Tomomi Kimura-Someya, Guy Leonard, Rex R. Malmstrom, Daniel R. Mende, Daniel K. Olson, Yuki Sudo, Sebastian Sudek, Thomas A. Richards, Edward F. DeLong, Patrick J. Keeling, Alyson E. Santoro, Mikako Shirouzu, Wataru Iwasaki, and Alexandra Z. Worden
Evolution
[An experimental test of the ovulatory homolog model of female orgasm](
Mihaela Pavlicev, Andreja Moset Zupan, Amanda Barry, Savannah Walters, Kristin M. Milano, Harvey J. Kliman, and Günter P. Wagner
[Climate cooling and clade competition likely drove the decline of lamniform sharks](
Fabien L. Condamine, Jules Romieu, and Guillaume Guinot
[The role of multilevel selection in host microbiome evolution](
Simon van Vliet and Michael Doebeli
[Experimental evolution of immunological specificity](
Kevin Ferro, Robert Peuß, Wentao Yang, Philip Rosenstiel, Hinrich Schulenburg, and Joachim Kurtz
Genetics
[The nucleosome core particle remembers its position through DNA replication and RNA transcription](
Gavin Schlissel and Jasper Rine
[RNA ligation precedes the retrotransposition of U6/LINE-1 chimeric RNA](
John B. Moldovan, Yifan Wang, Stewart Shuman, Ryan E. Mills, and John V. Moran
Immunology and Inflammation
[Inhibition of Δ24-dehydrocholesterol reductase activates pro-resolving lipid mediator biosynthesis and inflammation resolution](
Andreas Körner, Enchen Zhou, Christoph Müller, Yassene Mohammed, Sandra Herceg, Franz Bracher, Patrick C. N. Rensen, Yanan Wang, Valbona Mirakaj, and Martin Giera
[SerpinB1 controls encephalitogenic T helper cells in neuroinflammation](
Lifei Hou, Deepak A. Rao, Koichi Yuki, Jessica Cooley, Lauren A. Henderson, A. Helena Jonsson, Dion Kaiserman, Mark P. Gorman, Peter A. Nigrovic, Phillip I. Bird, Burkhard Becher, and Eileen Remold-O’Donnell
[Crystal structure of cis-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis](
Fangfang Chen, Peer Lukat, Azeem Ahmed Iqbal, Kyrill Saile, Volkhard Kaever, Joop van den Heuvel, Wulf Blankenfeldt, Konrad Büssow, and Frank Pessler
[Glioblastoma ablates pericytes antitumor immune function through aberrant up-regulation of chaperone-mediated autophagy](
Rut Valdor, David GarcÃa-Bernal, Dolores Riquelme, Carlos M. Martinez, Jose M. Moraleda, Ana Maria Cuervo, Fernando Macian, and Salvador Martinez
Medical Sciences
[Predicting kidney transplant outcomes with partial knowledge of HLA mismatch](
Charles F. Manski, Anat R. Tambur, and Michael Gmeiner
[Early detection and monitoring of cerebral ischemia using calcium-responsive MRI probes](
Tanja Savić, Giuseppe Gambino, Vahid S. Bokharaie, Hamid R. Noori, Nikos K. Logothetis, and Goran Angelovski
[Preclinical murine platform to evaluate therapeutic countermeasures against radiation-induced gastrointestinal syndrome](
Paul B. Romesser, Amanda S. Kim, Jeho Jeong, Allison Mayle, Lukas E. Dow, and Scott W. Lowe
[Aldh1b1 expression defines progenitor cells in the adult pancreas and is required for Kras-induced pancreatic cancer](
Ekaterina Mameishvili, Ioannis Serafimidis, Sara Iwaszkiewicz, Mathias Lesche, Susanne Reinhardt, Nora Bölicke, Maren Büttner, Dimitris Stellas, Adriana Papadimitropoulou, Matthias Szabolcs, Konstantinos Anastassiadis, Andreas Dahl, Fabian Theis, Argiris Efstratiadis, and Anthony Gavalas
[Parkinson’s disease-associated iPLA2-VIA/PLA2G6 regulates neuronal functions and α-synuclein stability through membrane remodeling](
Akio Mori, Taku Hatano, Tsuyoshi Inoshita, Kahori Shiba-Fukushima, Takahiro Koinuma, Hongrui Meng, Shin-ichiro Kubo, Spencer Spratt, Changxu Cui, Chikara Yamashita, Yoshimi Miki, Kei Yamamoto, Tetsuya Hirabayashi, Makoto Murakami, Yoshikazu Takahashi, Hideo Shindou, Takashi Nonaka, Masato Hasegawa, Ayami Okuzumi, Yuzuru Imai, and Nobutaka Hattori
Microbiology
[Immunization against poly-N-acetylglucosamine reduces neutrophil activation and GVHD while sparing microbial diversity](
Jan Hülsdünker, Oliver S. Thomas, Eileen Haring, Susanne Unger, Nicolás Gonzalo Núñez, Sonia Tugues, Zhan Gao, Sandra Duquesne, Colette Cywes-Bentley, Ozlem Oyardi, Susanne Kirschnek, Annette Schmitt-Graeff, Oliver Pabst, Christian Koenecke, Justus Duyster, Petya Apostolova, Martin J. Blaser, Burkhard Becher, Gerald B. Pier, Georg Häcker, and Robert Zeiser
[Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virus](
Eric D. Laing, Chanakha K. Navaratnarajah, Sofia Cheliout Da Silva, Stephanie R. Petzing, Yan Xu, Spencer L. Sterling, Glenn A. Marsh, Lin-Fa Wang, Moushimi Amaya, Dimitar B. Nikolov, Roberto Cattaneo, Christopher C. Broder, and Kai Xu
[NanoSIMS imaging reveals metabolic stratification within current-producing biofilms](
Grayson L. Chadwick, Fernanda Jiménez Otero, Jeffrey A. Gralnick, Daniel R. Bond, and Victoria J. Orphan
[African trypanosomes expressing multiple VSGs are rapidly eliminated by the host immune system](
Francisco Aresta-Branco, Margarida Sanches-Vaz, Fabio Bento, João A. Rodrigues, and Luisa M. Figueiredo
Neuroscience
[Task-based fMRI predicts response and remission to exposure therapy in obsessive-compulsive disorder](
David Pagliaccio, Rachel Middleton, Dianne Hezel, Shari Steinman, Ivar Snorrason, Marina Gershkovich, Raphael Campeas, Anthony Pinto, Page Van Meter, H. Blair Simpson, and Rachel Marsh
[The NMDA receptor activation by d-serine and glycine is controlled by an astrocytic Phgdh-dependent serine shuttle](
Samah Neame, Hazem Safory, Inna Radzishevsky, Ayelet Touitou, Francesco Marchesani, Marialaura Marchetti, Shai Kellner, Shai Berlin, Veronika N. Foltyn, Simone Engelender, Jean-Marie Billard, and Herman Wolosker
[A Tmc1 mutation reduces calcium permeability and expression of mechanoelectrical transduction channels in cochlear hair cells](
Maryline Beurg, Amanda Barlow, David N. Furness, and Robert Fettiplace
[Apparent thinning of human visual cortex during childhood is associated with myelination](
Vaidehi S. Natu, Jesse Gomez, Michael Barnett, Brianna Jeska, Evgeniya Kirilina, Carsten Jaeger, Zonglei Zhen, Siobhan Cox, Kevin S. Weiner, Nikolaus Weiskopf, and Kalanit Grill-Spector
[Cell models of lipid-rich α-synuclein aggregation validate known modifiers of α-synuclein biology and identify stearoyl-CoA desaturase](
Thibaut Imberdis, Joseph Negri, Nagendran Ramalingam, Elizabeth Terry-Kantor, Gary P. H. Ho, Saranna Fanning, Georgia Stirtz, Tae-Eun Kim, Oren A. Levy, Tracy L. Young-Pearse, Dennis Selkoe, and Ulf Dettmer
Plant Biology
[Fine control of aerenchyma and lateral root development through AUX/IAA- and ARF-dependent auxin signaling](
Takaki Yamauchi, Akihiro Tanaka, Hiroki Inahashi, Naoko K. Nishizawa, Nobuhiro Tsutsumi, Yoshiaki Inukai, and Mikio Nakazono
[Maize sugary enhancer1 (se1) is a gene affecting endosperm starch metabolism](
Xia Zhang, Karl J. Haro von Mogel, Vai S. Lor, Candice N. Hirsch, Brian De Vries, Heidi F. Kaeppler, William F. Tracy, and Shawn M. Kaeppler
Population Biology
[Future epidemiological and economic impacts of universal influenza vaccines](
Pratha Sah, Jorge A. Alfaro-Murillo, Meagan C. Fitzpatrick, Kathleen M. Neuzil, Lauren A. Meyers, Burton H. Singer, and Alison P. Galvani
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Corrections
[Correction for Arlinghaus et al., Opinion: Governing the recreational dimension of global fisheries](
[Correction for Kalogriopoulos et al., Structural basis for GPCR-independent activation of heterotrimeric Gi proteins](
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Retractions
[Retraction for Bearzi et al., Identification of a coronary vascular progenitor cell in the human heart](
[Retraction for Boni et al., Notch1 regulates the fate of cardiac progenitor cells](
[Cover]
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