PNAS Table of Contents for September 24, 2019; Vol. 116, No. 39

[PNAS] [Serotonin](/cgi/adclick/?ad=54325&adclick=true&url=https%3A%2F%2Fwww.pnas.org%2Fpage%2Fmedia%2Fpodcasts)   [September 24, 2019; Vol. 116, No. 39]( ) This Week in PNAS [In This Issue]( --------------------------------------------------------------- Inner Workings [Inner Workings: Lyme disease vaccines face familiar challenges, both societal and scientific]( Leah Shaffer An over-the-shoulder look at scientists at work. --------------------------------------------------------------- Core Concepts [Core Concept: To improve weather and climate models, researchers are chasing atmospheric gravity waves]( Adam Mann A brief introduction to emerging topics in science. --------------------------------------------------------------- Commentaries [Production of hydrogen peroxide enabled by microdroplets]( Chongqin Zhu and Joseph S. Francisco [Slippery ribosomes prefer shapeshifting mRNAs]( Jonathan D. Dinman [An unfolding role for ankyrin-G at the axon initial segment]( James L. Salzer --------------------------------------------------------------- Perspective [Signaling the trustworthiness of science]( Kathleen Hall Jamieson, Marcia McNutt, Veronique Kiermer, and Richard Sever --------------------------------------------------------------- Letters [Distributional semantics as a source of visual knowledge]( Molly Lewis, Martin Zettersten, and Gary Lupyan [Reply to Lewis et al.: Inference is key to learning appearance from language, for humans and distributional semantic models alike]( Judy S. Kim, Giulia V. Elli, and Marina Bedny [Take a deep breath: Multiecho fMRI denoising effectively removes head motion artifacts, obviating the need for global signal regression]( R. Nathan Spreng, Sara Fernández-Cabello, Gary R. Turner, and W. Dale Stevens [Reply to Spreng et al.: Multiecho fMRI denoising does not remove global motion-associated respiratory signals]( Jonathan D. Power, Charles J. Lynch, Adrian W. Gilmore, Stephen J. Gotts, and Alex Martin --------------------------------------------------------------- Brief Reports [Autism spectrum traits predict higher social psychological skill]( Anton Gollwitzer, Cameron Martel, James C. McPartland, and John A. Bargh [Scleral pigmentation leads to conspicuous, not cryptic, eye morphology in chimpanzees]( Juan Olvido Perea-García, Mariska E. Kret, Antónia Monteiro, and Catherine Hobaiter --------------------------------------------------------------- Physical Sciences Applied Physical Sciences [Measuring actual learning versus feeling of learning in response to being actively engaged in the classroom]( Louis Deslauriers, Logan S. McCarty, Kelly Miller, Kristina Callaghan, and Greg Kestin [Revealing angular momentum transfer channels and timescales in the ultrafast demagnetization process of ferromagnetic semiconductors]( Zhanghui Chen, Jun-Wei Luo, and Lin-Wang Wang [Fluid pumping and active flexoelectricity can promote lumen nucleation in cell assemblies]( Charlie Duclut, Niladri Sarkar, Jacques Prost, and Frank Jülicher Biophysics and Computational Biology [Water follows polar and nonpolar protein surface domains]( Baofu Qiao, Felipe Jiménez-Ángeles, Trung Dac Nguyen, and Monica Olvera de la Cruz [A computational framework for DNA sequencing microscopy]( Ian T. Hoffecker, Yunshi Yang, Giulio Bernardinelli, Pekka Orponen, and Björn Högberg [Three archetypical classes of macromolecular regulators of protein liquid–liquid phase separation]( Archishman Ghosh, Konstantinos Mazarakos, and Huan-Xiang Zhou [Intracellular redox potential is correlated with miRNA expression in MCF7 cells under hypoxic conditions]( Hannah Johnston, Paul Dickinson, Alasdair Ivens, Amy H. Buck, R. D. Levine, Francoise Remacle, and Colin J. Campbell Chemistry [A safe and sustainable bacterial cellulose nanofiber separator for lithium rechargeable batteries]( Hyeokjo Gwon, Kitae Park, Soon-Chun Chung, Ryoung-Hee Kim, Jin Kyu Kang, Sang Min Ji, Nag-Jong Kim, Sunghaeng Lee, Jun-Hwan Ku, Eun Cheol Do, Sujin Park, Minsang Kim, Woo Yong Shim, Hong Soon Rhee, Jae-Young Kim, Jieun Kim, Tae Yong Kim, Yoshitaka Yamaguchi, Ryo Iwamuro, Shunsuke Saito, Gahee Kim, In-Sun Jung, Hyokeun Park, Chanhee Lee, Seungyeon Lee, Woo Sung Jeon, Woo Dae Jang, Hyun Uk Kim, Sang Yup Lee, Dongmin Im, Seok-Gwang Doo, Sang Yoon Lee, Hyun Chul Lee, and Jin Hwan Park [Spontaneous generation of hydrogen peroxide from aqueous microdroplets]( Jae Kyoo Lee, Katherine L. Walker, Hyun Soo Han, Jooyoun Kang, Fritz B. Prinz, Robert M. Waymouth, Hong Gil Nam, and Richard N. Zare [Collective multipole oscillations direct the plasmonic coupling at the nanojunction interfaces]( Nasrin Hooshmand and Mostafa A. El-Sayed [Unbiased atomistic insight in the competing nucleation mechanisms of methane hydrates]( Arjun, Thom A. Berendsen, and Peter G. Bolhuis [Mechanism of activation of the human cysteine desulfurase complex by frataxin]( Shachin Patra and David P. Barondeau Earth, Atmospheric, and Planetary Sciences [Decadal increase in Arctic dimethylsulfide emission]( Martí Galí, Emmanuel Devred, Marcel Babin, and Maurice Levasseur [Intermediate-scale horizontal isoprene concentrations in the near-canopy forest atmosphere and implications for emission heterogeneity]( Carla E. Batista, Jianhuai Ye, Igor O. Ribeiro, Patricia C. Guimarães, Adan S. S. Medeiros, Rafael G. Barbosa, Rafael L. Oliveira, Sergio Duvoisin Jr., Kolby J. Jardine, Dasa Gu, Alex B. Guenther, Karena A. McKinney, Leila D. Martins, Rodrigo A. F. Souza, and Scot T. Martin [Phase transitions beyond post-perovskite in NaMgF3 to 160 GPa]( Rajkrishna Dutta, Eran Greenberg, Vitali B. Prakapenka, and Thomas S. Duffy [A round Earth for climate models]( Michael J. Prather and Juno C. Hsu [Spherical tarball particles form through rapid chemical and physical changes of organic matter in biomass-burning smoke]( Kouji Adachi, Arthur J. Sedlacek III, Lawrence Kleinman, Stephen R. Springston, Jian Wang, Duli Chand, John M. Hubbe, John E. Shilling, Timothy B. Onasch, Takeshi Kinase, Kohei Sakata, Yoshio Takahashi, and Peter R. Buseck [The first day of the Cenozoic]( Sean P. S. Gulick, Timothy J. Bralower, Jens Ormö, Brendon Hall, Kliti Grice, Bettina Schaefer, Shelby Lyons, Katherine H. Freeman, Joanna V. Morgan, Natalia Artemieva, Pim Kaskes, Sietze J. de Graaff, Michael T. Whalen, Gareth S. Collins, Sonia M. Tikoo, Christina Verhagen, Gail L. Christeson, Philippe Claeys, Marco J. L. Coolen, Steven Goderis, Kazuhisa Goto, Richard A. F. Grieve, Naoma McCall, Gordon R. Osinski, Auriol S. P. Rae, Ulrich Riller, Jan Smit, Vivi Vajda, Axel Wittmann, and the Expedition 364 Scientists [Atmosphere–ocean oxygen and productivity dynamics during early animal radiations]( Tais W. Dahl, James N. Connelly, Da Li, Artem Kouchinsky, Benjamin C. Gill, Susannah Porter, Adam C. Maloof, and Martin Bizzarro Engineering [Digital-resolution detection of microRNA with single-base selectivity by photonic resonator absorption microscopy]( Taylor D. Canady, Nantao Li, Lucas D. Smith, Yi Lu, Manish Kohli, Andrew M. Smith, and Brian T. Cunningham [What network motifs tell us about resilience and reliability of complex networks]( Asim K. Dey, Yulia R. Gel, and H. Vincent Poor Mathematics [Interesting identities involving weighted representations of integers as sums of arbitrarily many squares]( Min-Joo Jang, Ben Kane, Winfried Kohnen, and Siu Hang Man --------------------------------------------------------------- Social Sciences Anthropology [Relief food subsistence revealed by microparticle and proteomic analyses of dental calculus from victims of the Great Irish Famine]( Jonny Geber, Monica Tromp, Ashley Scott, Abigail Bouwman, Paolo Nanni, Jonas Grossmann, Jessica Hendy, and Christina Warinner Psychological and Cognitive Sciences [Measuring actual learning versus feeling of learning in response to being actively engaged in the classroom]( Louis Deslauriers, Logan S. McCarty, Kelly Miller, Kristina Callaghan, and Greg Kestin [Despite high objective numeracy, lower numeric confidence relates to worse financial and medical outcomes]( Ellen Peters, Mary Kate Tompkins, Melissa A. Z. Knoll, Stacy P. Ardoin, Brittany Shoots-Reinhard, and Alexa Simon Meara [Preserved capacity for learning statistical regularities and directing selective attention after hippocampal lesions]( Nuttida Rungratsameetaweemana, Larry R. Squire, and John T. Serences [Subcortical connectivity correlates selectively with attention’s effects on spatial choice bias]( Varsha Sreenivasan and Devarajan Sridharan Social Sciences [The long-term impact of the Communist Revolution on social stratification in contemporary China]( Yu Xie and Chunni Zhang --------------------------------------------------------------- Biological Sciences Agricultural Sciences [Quantifying the contribution of sequence variants with regulatory and evolutionary significance to 34 bovine complex traits]( Ruidong Xiang, Irene van den Berg, Iona M. MacLeod, Benjamin J. Hayes, Claire P. Prowse-Wilkins, Min Wang, Sunduimijid Bolormaa, Zhiqian Liu, Simone J. Rochfort, Coralie M. Reich, Brett A. Mason, Christy J. Vander Jagt, Hans D. Daetwyler, Mogens S. Lund, Amanda J. Chamberlain, and Michael E. Goddard Anthropology [The composition of a Neandertal social group revealed by the hominin footprints at Le Rozel (Normandy, France)]( Jérémy Duveau, Gilles Berillon, Christine Verna, Gilles Laisné, and Dominique Cliquet Applied Biological Sciences [Engineering energetically efficient transport of dicarboxylic acids in yeast Saccharomyces cerevisiae]( Behrooz Darbani, Vratislav Stovicek, Steven Axel van der Hoek, and Irina Borodina Biochemistry [A safe and sustainable bacterial cellulose nanofiber separator for lithium rechargeable batteries]( Hyeokjo Gwon, Kitae Park, Soon-Chun Chung, Ryoung-Hee Kim, Jin Kyu Kang, Sang Min Ji, Nag-Jong Kim, Sunghaeng Lee, Jun-Hwan Ku, Eun Cheol Do, Sujin Park, Minsang Kim, Woo Yong Shim, Hong Soon Rhee, Jae-Young Kim, Jieun Kim, Tae Yong Kim, Yoshitaka Yamaguchi, Ryo Iwamuro, Shunsuke Saito, Gahee Kim, In-Sun Jung, Hyokeun Park, Chanhee Lee, Seungyeon Lee, Woo Sung Jeon, Woo Dae Jang, Hyun Uk Kim, Sang Yup Lee, Dongmin Im, Seok-Gwang Doo, Sang Yoon Lee, Hyun Chul Lee, and Jin Hwan Park [Mechanism of activation of the human cysteine desulfurase complex by frataxin]( Shachin Patra and David P. Barondeau [Chromatin conformation remains stable upon extensive transcriptional changes driven by heat shock]( Judhajeet Ray, Paul R. Munn, Anniina Vihervaara, James J. Lewis, Abdullah Ozer, Charles G. Danko, and John T. Lis [CMT disease severity correlates with mutation-induced open conformation of histidyl-tRNA synthetase, not aminoacylation loss, in patient cells]( David Blocquel, Litao Sun, Zaneta Matuszek, Sheng Li, Thomas Weber, Bernhard Kuhle, Grace Kooi, Na Wei, Jonathan Baets, Tao Pan, Paul Schimmel, and Xiang-Lei Yang [Chemical and structural analysis of a photoactive vertebrate cryptochrome from pigeon]( Brian D. Zoltowski, Yogarany Chelliah, Anushka Wickramaratne, Lauren Jarocha, Nischal Karki, Wei Xu, Henrik Mouritsen, Peter J. Hore, Ryan E. Hibbs, Carla B. Green, and Joseph S. Takahashi [Energetics of the exchangeable quinone, QB, in Photosystem II]( Sven De Causmaecker, Jeffrey S. Douglass, Andrea Fantuzzi, Wolfgang Nitschke, and A. William Rutherford [PHF2 histone demethylase prevents DNA damage and genome instability by controlling cell cycle progression of neural progenitors]( Stella Pappa, Natalia Padilla, Simona Iacobucci, Marta Vicioso, Elena Álvarez de la Campa, Claudia Navarro, Elia Marcos, Xavier de la Cruz, and Marian A. Martínez-Balbás Biophysics and Computational Biology [Three archetypical classes of macromolecular regulators of protein liquid–liquid phase separation]( Archishman Ghosh, Konstantinos Mazarakos, and Huan-Xiang Zhou [Revisiting the protomotive vectorial motion of F0-ATPase]( Chen Bai and Arieh Warshel [Spatial transcriptome profiling by MERFISH reveals subcellular RNA compartmentalization and cell cycle-dependent gene expression]( Chenglong Xia, Jean Fan, George Emanuel, Junjie Hao, and Xiaowei Zhuang [Complex dynamics under tension in a high-efficiency frameshift stimulatory structure]( Matthew T. J. Halma, Dustin B. Ritchie, Tonia R. Cappellano, Krishna Neupane, and Michael T. Woodside [Polymer effects modulate binding affinities in disordered proteins]( Renee Vancraenenbroeck, Yair S. Harel, Wenwei Zheng, and Hagen Hofmann [An ensemble of cryo-EM structures of TRiC reveal its conformational landscape and subunit specificity]( Mingliang Jin, Wenyu Han, Caixuan Liu, Yunxiang Zang, Jiawei Li, Fangfang Wang, Yanxing Wang, and Yao Cong Cell Biology [Regulation of GSK3 cellular location by FRAT modulates mTORC1-dependent cell growth and sensitivity to rapamycin]( Long He, Dennis Liang Fei, Michal J. Nagiec, Anders P. Mutvei, Andreas Lamprakis, Bo Yeon Kim, and John Blenis [Lgr5+ pericentral hepatocytes are self-maintained in normal liver regeneration and susceptible to hepatocarcinogenesis]( Chow Hiang Ang, Shih Han Hsu, Fusheng Guo, Chong Teik Tan, Victor C. Yu, Jane E. Visvader, Pierce K. H. Chow, and Nai Yang Fu [Development and utilization of human decidualization reporter cell line uncovers new modulators of female fertility]( Meade Haller, Yan Yin, and Liang Ma [Human papillomavirus E7 oncoprotein targets RNF168 to hijack the host DNA damage response]( Justine Sitz, Sophie Anne Blanchet, Steven F. Gameiro, Elise Biquand, Tia M. Morgan, Maxime Galloy, Julien Dessapt, Elise G. Lavoie, Andréanne Blondeau, Brandon C. Smith, Joe S. Mymryk, Cary A. Moody, and Amélie Fradet-Turcotte Ecology [Hydrologic variability contributes to reduced survival through metamorphosis in a stream salamander]( Winsor H. Lowe, Leah K. Swartz, Brett R. Addis, and Gene E. Likens Evolution [Evolution of the vomer and its implications for cranial kinesis in Paraves]( Han Hu, Gabriele Sansalone, Stephen Wroe, Paul G. McDonald, Jingmai K. O’Connor, Zhiheng Li, Xing Xu, and Zhonghe Zhou [Chestnut-crowned babbler calls are composed of meaningless shared building blocks]( Sabrina Engesser, Jennifer L. Holub, Louis G. O’Neill, Andrew F. Russell, and Simon W. Townsend [Diversification of giant and large eukaryotic dsDNA viruses predated the origin of modern eukaryotes]( Julien Guglielmini, Anthony C. Woo, Mart Krupovic, Patrick Forterre, and Morgan Gaia Genetics [Evolution-based screening enables genome-wide prioritization and discovery of DNA repair genes]( Gregory J. Brunette, Mohd A. Jamalruddin, Robert A. Baldock, Nathan L. Clark, and Kara A. Bernstein Immunology and Inflammation [Immunogenicity of a rheumatoid arthritis protective sequence when acquired through microchimerism]( Sami B. Kanaan, Oyku Sensoy, Zhen Yan, Vijayakrishna K. Gadi, Michael L. Richardson, and J. Lee Nelson Medical Sciences [Digital-resolution detection of microRNA with single-base selectivity by photonic resonator absorption microscopy]( Taylor D. Canady, Nantao Li, Lucas D. Smith, Yi Lu, Manish Kohli, Andrew M. Smith, and Brian T. Cunningham [Proteomic analyses of ECM during pancreatic ductal adenocarcinoma progression reveal different contributions by tumor and stromal cells]( Chenxi Tian, Karl R. Clauser, Daniel Öhlund, Steffen Rickelt, Ying Huang, Mala Gupta, D. R. Mani, Steven A. Carr, David A. Tuveson, and Richard O. Hynes [The single-cell transcriptomic landscape of early human diabetic nephropathy]( Parker C. Wilson, Haojia Wu, Yuhei Kirita, Kohei Uchimura, Nicolas Ledru, Helmut G. Rennke, Paul A. Welling, Sushrut S. Waikar, and Benjamin D. Humphreys [p53 prevents doxorubicin cardiotoxicity independently of its prototypical tumor suppressor activities]( Jie Li, Ping-yuan Wang, Nathaniel A. Long, Jie Zhuang, Danielle A. Springer, Jizhong Zou, Yongshun Lin, Christopher K. E. Bleck, Ji-Hoon Park, Ju-Gyeong Kang, and Paul M. Hwang [Neurokinin-1 receptor is an effective target for treating leukemia by inducing oxidative stress through mitochondrial calcium overload]( Chentao Ge, Hemiao Huang, Feiyan Huang, Tianxin Yang, Tengfei Zhang, Hongzhang Wu, Hanwei Zhou, Qi Chen, Yue Shi, Yanfang Sun, Liangjue Liu, Xi Wang, Richard B. Pearson, Yihai Cao, Jian Kang, and Caiyun Fu Microbiology [Mode-of-action profiling reveals glutamine synthetase as a collateral metabolic vulnerability of M. tuberculosis to bedaquiline]( Zhe Wang, Vijay Soni, Gwendolyn Marriner, Takushi Kaneko, Helena I. M. Boshoff, Clifton E. Barry III, and Kyu Y. Rhee [Targeted mobilization of Lrig1+ gastric epithelial stem cell populations by a carcinogenic Helicobacter pylori type IV secretion system]( Lydia E. Wroblewski, Eunyoung Choi, Christine Petersen, Alberto G. Delgado, M. Blanca Piazuelo, Judith Romero-Gallo, Tyler L. Lantz, Yana Zavros, Robert J. Coffey, James R. Goldenring, Anne E. Zemper, and Richard M. Peek Jr. [Rickettsia conorii O antigen is the target of bactericidal Weil–Felix antibodies]( Hwan Keun Kim, Ranjan Premaratna, Dominique M. Missiakas, and Olaf Schneewind [Phase variation in Mycobacterium tuberculosis glpK produces transiently heritable drug tolerance]( Hassan Safi, Pooja Gopal, Subramanya Lingaraju, Shuyi Ma, Carly Levine, Veronique Dartois, Michelle Yee, Liping Li, Landry Blanc, Hsin-Pin Ho Liang, Seema Husain, Mainul Hoque, Patricia Soteropoulos, Tige Rustad, David R. Sherman, Thomas Dick, and David Alland [Revealing the metabolic capacity of Streblomastix strix and its bacterial symbionts using single-cell metagenomics]( Sebastian C. Treitli, Martin Kolisko, Filip Husník, Patrick J. Keeling, and Vladimír Hampl [Large-scale identification of pathogen essential genes during coinfection with sympatric and allopatric microbes]( Gina R. Lewin, Apollo Stacy, Kelly L. Michie, Richard J. Lamont, and Marvin Whiteley [Distinct intraspecies virulence mechanisms regulated by a conserved transcription factor]( James P. R. Connolly, Nicky O’Boyle, Natasha C. A. Turner, Douglas F. Browning, and Andrew J. Roe Neuroscience [Preserved capacity for learning statistical regularities and directing selective attention after hippocampal lesions]( Nuttida Rungratsameetaweemana, Larry R. Squire, and John T. Serences [Subcortical connectivity correlates selectively with attention’s effects on spatial choice bias]( Varsha Sreenivasan and Devarajan Sridharan [Neurodevelopmental mutation of giant ankyrin-G disrupts a core mechanism for axon initial segment assembly]( Rui Yang, Kathryn K. Walder-Christensen, Samir Lalani, Haidun Yan, Irene Díez García-Prieto, Sara Álvarez, Alberto Fernández-Jaén, Laura Speltz, Yong-Hui Jiang, and Vann Bennett [RNA editing alterations define manifestation of prion diseases]( Eirini Kanata, Franc Llorens, Dimitra Dafou, Athanasios Dimitriadis, Katrin Thüne, Konstantinos Xanthopoulos, Nikolaos Bekas, Juan Carlos Espinosa, Matthias Schmitz, Alba Marín-Moreno, Vincenzo Capece, Orr Shormoni, Olivier Andréoletti, Stefan Bonn, Juan María Torres, Isidre Ferrer, Inga Zerr, and Theodoros Sklaviadis Plant Biology [NEEDLE1 encodes a mitochondria localized ATP-dependent metalloprotease required for thermotolerant maize growth]( Qiujie Liu, Mary Galli, Xue Liu, Silvia Federici, Amy Buck, Jon Cody, Massimo Labra, and Andrea Gallavotti [Oligogalacturonide production upon Arabidopsis thaliana–Botrytis cinerea interaction]( Aline Voxeur, Olivier Habrylo, Stéphanie Guénin, Fabien Miart, Marie-Christine Soulié, Christophe Rihouey, Corinne Pau-Roblot, Jean-Marc Domon, Laurent Gutierrez, Jérôme Pelloux, Grégory Mouille, Mathilde Fagard, Herman Höfte, and Samantha Vernhettes Systems Biology [Intracellular redox potential is correlated with miRNA expression in MCF7 cells under hypoxic conditions]( Hannah Johnston, Paul Dickinson, Alasdair Ivens, Amy H. Buck, R. D. Levine, Francoise Remacle, and Colin J. Campbell --------------------------------------------------------------- Corrections [Correction for Sever et al., SLAMF9 regulates pDC homeostasis and function in health and disease]( [Correction for Seo et al., TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8+ T cell exhaustion]( [Cover] --------------------------------------------------------------- This message was sent to {EMAIL}. [Unsubscribe]( from or [edit]( your subscription for this service. Or by mail: Customer Service * 973 University Avenue * Los Gatos, CA 95032 * U.S.A. Copyright © 2019 by the National Academy of Sciences