PNAS Table of Contents for August 27, 2019; Vol. 116, No. 35

[PNAS] [Podcast Interfaces](/cgi/adclick/?ad=54210&adclick=true&url=https%3A%2F%2Fwww.pnas.org%2Fpage%2Fmedia%2Fpodcasts%23interfaces)   [August 27, 2019; Vol. 116, No. 35]( ) This Week in PNAS [In This Issue]( --------------------------------------------------------------- News Feature [News Feature: The quest for the sustainable city]( M. Mitchell Waldrop An in-depth look at trending science issues. --------------------------------------------------------------- Profile [Profile of Claire L. Parkinson]( Brian Doctrow --------------------------------------------------------------- Commentaries [Ubiquitin in disguise unveils a cryptic binding site in 1.2-MDa anaphase-promoting complex/cyclosome]( Kylie J. Walters [Unknown actor in adipose tissue metabolism hiding in plain sight]( Sheila Collins --------------------------------------------------------------- Perspective [Intermembrane transport: Glycerophospholipid homeostasis of the Gram-negative cell envelope]( Matthew J. Powers and M. Stephen Trent --------------------------------------------------------------- Letters [Do X-ray spectroscopies provide evidence for continuous distribution models of water at ambient conditions?]( Lars G. M. Pettersson, Yoshihisa Harada, and Anders Nilsson [Reply to Pettersson et al.: Why X-ray spectral features are compatible to continuous distribution models in ambient water]( Johannes Niskanen, Mattis Fondell, Christoph J. Sahle, Sebastian Eckert, Raphael M. Jay, Keith Gilmore, Annette Pietzsch, Marcus Dantz, Xingye Lu, Daniel E. McNally, Thorsten Schmitt, Vinicius Vaz da Cruz, Victor Kimberg, Faris Gel’mukhanov, and Alexander Föhlisch [Scenarios where increased population size can enhance cumulative cultural evolution are likely common]( Jason P. Martens [Reply to Martens: Various factors may enable large populations to enhance cumulative cultural evolution, but more evidence is needed]( Nicolas Fay, Naomi De Kleine, Bradley Walker, and Christine A. Caldwell --------------------------------------------------------------- Physical Sciences Applied Physical Sciences [Ballistic thermal phonons traversing nanocrystalline domains in oriented polyethylene]( Andrew B. Robbins, Stavros X. Drakopoulos, Ignacio Martin-Fabiani, Sara Ronca, and Austin J. Minnich Biophysics and Computational Biology [Hydrophobic catalysis and a potential biological role of DNA unstacking induced by environment effects]( Bobo Feng, Robert P. Sosa, Anna K. F. Mårtensson, Kai Jiang, Alex Tong, Kevin D. Dorfman, Masayuki Takahashi, Per Lincoln, Carlos J. Bustamante, Fredrik Westerlund, and Bengt Nordén [High stretchability, strength, and toughness of living cells enabled by hyperelastic vimentin intermediate filaments]( Jiliang Hu, Yiwei Li, Yukun Hao, Tianqi Zheng, Satish K. Gupta, German Alberto Parada, Huayin Wu, Shaoting Lin, Shida Wang, Xuanhe Zhao, Robert D. Goldman, Shengqiang Cai, and Ming Guo [Prebiotic amino acids bind to and stabilize prebiotic fatty acid membranes]( Caitlin E. Cornell, Roy A. Black, Mengjun Xue, Helen E. Litz, Andrew Ramsay, Moshe Gordon, Alexander Mileant, Zachary R. Cohen, James A. Williams, Kelly K. Lee, Gary P. Drobny, and Sarah L. Keller [Nucleosome positions alone can be used to predict domains in yeast chromosomes]( Oliver Wiese, Davide Marenduzzo, and Chris A. Brackley [Autophosphorylation is sufficient to release Mps1 kinase from native kinetochores]( Lori B. Koch, Kwaku N. Opoku, Yi Deng, Adrienne Barber, Aimee J. Littleton, Nitobe London, Sue Biggins, and Charles L. Asbury Chemistry [Nanoscale oxygen defect gradients in UO2+x surfaces]( Steven R. Spurgeon, Michel Sassi, Colin Ophus, Joanne E. Stubbs, Eugene S. Ilton, and Edgar C. Buck Earth, Atmospheric, and Planetary Sciences [Mesoscale eddies release pelagic sharks from thermal constraints to foraging in the ocean twilight zone]( Camrin D. Braun, Peter Gaube, Tane H. Sinclair-Taylor, Gregory B. Skomal, and Simon R. Thorrold [Impacts of climate change on future air quality and human health in China]( Chaopeng Hong, Qiang Zhang, Yang Zhang, Steven J. Davis, Dan Tong, Yixuan Zheng, Zhu Liu, Dabo Guan, Kebin He, and Hans Joachim Schellnhuber [Rainfall variations in central Indo-Pacific over the past 2,700 y]( Liangcheng Tan, Chuan-Chou Shen, Ludvig Löwemark, Sakonvan Chawchai, R. Lawrence Edwards, Yanjun Cai, Sebastian F. M. Breitenbach, Hai Cheng, Yu-Chen Chou, Helmut Duerrast, Judson W. Partin, Wenju Cai, Akkaneewut Chabangborn, Yongli Gao, Ola Kwiecien, Chung-Che Wu, Zhengguo Shi, Huang-Hsiung Hsu, and Barbara Wohlfarth [A productivity collapse to end Earth’s Great Oxidation]( Malcolm S. W. Hodgskiss, Peter W. Crockford, Yongbo Peng, Boswell A. Wing, and Tristan J. Horner Physics [Graphene-like monolayer monoxides and monochlorides]( Bingcheng Luo, Yuan Yao, Enke Tian, Hongzhou Song, Xiaohui Wang, Guowu Li, Kai Xi, Baiwen Li, Haifeng Song, and Longtu Li [Motility-limited aggregation of mammary epithelial cells into fractal-like clusters]( Susan E. Leggett, Zachary J. Neronha, Dhananjay Bhaskar, Jea Yun Sim, Theodora Myrto Perdikari, and Ian Y. Wong --------------------------------------------------------------- Social Sciences Environmental Sciences [Mapping the effects of drought on child stunting]( Matthew W. Cooper, Molly E. Brown, Stefan Hochrainer-Stigler, Georg Pflug, Ian McCallum, Steffen Fritz, Julie Silva, and Alexander Zvoleff Psychological and Cognitive Sciences [Race influences professional investors’ financial judgments]( Sarah Lyons-Padilla, Hazel Rose Markus, Ashby Monk, Sid Radhakrishna, Radhika Shah, Norris A. “Daryn” Dodson IV, and Jennifer L. Eberhardt Sustainability Science [Impacts of climate change on future air quality and human health in China]( Chaopeng Hong, Qiang Zhang, Yang Zhang, Steven J. Davis, Dan Tong, Yixuan Zheng, Zhu Liu, Dabo Guan, Kebin He, and Hans Joachim Schellnhuber --------------------------------------------------------------- Biological Sciences Anthropology [Ancient pigs reveal a near-complete genomic turnover following their introduction to Europe]( Laurent A. F. Frantz, James Haile, Audrey T. Lin, Amelie Scheu, Christina Geörg, Norbert Benecke, Michelle Alexander, Anna Linderholm, Victoria E. Mullin, Kevin G. Daly, Vincent M. Battista, Max Price, Kurt J. Gron, Panoraia Alexandri, Rose-Marie Arbogast, Benjamin Arbuckle, Adrian Bӑlӑşescu, Ross Barnett, László Bartosiewicz, Gennady Baryshnikov, Clive Bonsall, Dušan Borić, Adina Boroneanţ, Jelena Bulatović, Canan Çakirlar, José-Miguel Carretero, John Chapman, Mike Church, Richard Crooijmans, Bea De Cupere, Cleia Detry, Vesna Dimitrijevic, Valentin Dumitraşcu, Louis du Plessis, Ceiridwen J. Edwards, Cevdet Merih Erek, Aslı Erim-Özdoğan, Anton Ervynck, Domenico Fulgione, Mihai Gligor, Anders Götherström, Lionel Gourichon, Martien A.M. Groenen, Daniel Helmer, Hitomi Hongo, Liora K. Horwitz, Evan K. Irving-Pease, Ophélie Lebrasseur, Joséphine Lesur, Caroline Malone, Ninna Manaseryan, Arkadiusz Marciniak, Holley Martlew, Marjan Mashkour, Roger Matthews, Giedre Motuzaite Matuzeviciute, Sepideh Maziar, Erik Meijaard, Tom McGovern, Hendrik-Jan Megens, Rebecca Miller, Azadeh Fatemeh Mohaseb, Jörg Orschiedt, David Orton, Anastasia Papathanasiou, Mike Parker Pearson, Ron Pinhasi, Darko Radmanović, François-Xavier Ricaut, Mike Richards, Richard Sabin, Lucia Sarti, Wolfram Schier, Shiva Sheikhi, Elisabeth Stephan, John R. Stewart, Simon Stoddart, Antonio Tagliacozzo, Nenad Tasić, Katerina Trantalidou, Anne Tresset, Cristina Valdiosera, Youri van den Hurk, Sophie Van Poucke, Jean-Denis Vigne, Alexander Yanevich, Andrea Zeeb-Lanz, Alexandros Triantafyllidis, M. Thomas P. Gilbert, Jörg Schibler, Peter Rowley-Conwy, Melinda Zeder, Joris Peters, Thomas Cucchi, Daniel G. Bradley, Keith Dobney, Joachim Burger, Allowen Evin, Linus Girdland-Flink, and Greger Larson Biochemistry [Hydrophobic catalysis and a potential biological role of DNA unstacking induced by environment effects]( Bobo Feng, Robert P. Sosa, Anna K. F. Mårtensson, Kai Jiang, Alex Tong, Kevin D. Dorfman, Masayuki Takahashi, Per Lincoln, Carlos J. Bustamante, Fredrik Westerlund, and Bengt Nordén [Prebiotic amino acids bind to and stabilize prebiotic fatty acid membranes]( Caitlin E. Cornell, Roy A. Black, Mengjun Xue, Helen E. Litz, Andrew Ramsay, Moshe Gordon, Alexander Mileant, Zachary R. Cohen, James A. Williams, Kelly K. Lee, Gary P. Drobny, and Sarah L. Keller [Characterization of glutamyl-tRNA–dependent dehydratases using nonreactive substrate mimics]( Ian R. Bothwell, Dillon P. Cogan, Terry Kim, Christopher J. Reinhardt, Wilfred A. van der Donk, and Satish K. Nair [The crystal structure of human microsomal triglyceride transfer protein]( Ekaterina I. Biterova, Michail N. Isupov, Ronan M. Keegan, Andrey A. Lebedev, Anil A. Sohail, Inam Liaqat, Heli I. Alanen, and Lloyd W. Ruddock [HuR counteracts miR-330 to promote STAT3 translation during inflammation-induced muscle wasting]( Souad Mubaid, Jennifer F. Ma, Amr Omer, Kholoud Ashour, Xian J. Lian, Brenda J. Sanchez, Samantha Robinson, Anne Cammas, Virginie Dormoy-Raclet, Sergio Di Marco, Sridar V. Chittur, Scott A. Tenenbaum, and Imed-Eddine Gallouzi [A pathway linking translation stress to checkpoint kinase 2 signaling in Neurospora crassa]( Axel C. R. Diernfellner, Linda Lauinger, Anton Shostak, and Michael Brunner [Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site]( Edmond R. Watson, Christy R. R. Grace, Wei Zhang, Darcie J. Miller, Iain F. Davidson, J. Rajan Prabu, Shanshan Yu, Derek L. Bolhuis, Elizaveta T. Kulko, Ronnald Vollrath, David Haselbach, Holger Stark, Jan-Michael Peters, Nicholas G. Brown, Sachdev S. Sidhu, and Brenda A. Schulman [Second harmonic generation detection of Ras conformational changes and discovery of a small molecule binder]( Elizabeth Donohue, Sina Khorsand, Gabriel Mercado, Kristen M. Varney, Paul T. Wilder, Wenbo Yu, Alexander D. MacKerell Jr., Patrick Alexander, Que N. Van, Ben Moree, Andrew G. Stephen, David J. Weber, Joshua Salafsky, and Frank McCormick Biophysics and Computational Biology [High stretchability, strength, and toughness of living cells enabled by hyperelastic vimentin intermediate filaments]( Jiliang Hu, Yiwei Li, Yukun Hao, Tianqi Zheng, Satish K. Gupta, German Alberto Parada, Huayin Wu, Shaoting Lin, Shida Wang, Xuanhe Zhao, Robert D. Goldman, Shengqiang Cai, and Ming Guo [Motility-limited aggregation of mammary epithelial cells into fractal-like clusters]( Susan E. Leggett, Zachary J. Neronha, Dhananjay Bhaskar, Jea Yun Sim, Theodora Myrto Perdikari, and Ian Y. Wong [Nucleosome positions alone can be used to predict domains in yeast chromosomes]( Oliver Wiese, Davide Marenduzzo, and Chris A. Brackley [Structural and functional analyses of photosystem II in the marine diatom Phaeodactylum tricornutum]( Orly Levitan, Muyuan Chen, Xuyuan Kuang, Kuan Yu Cheong, Jennifer Jiang, Melissa Banal, Nikhita Nambiar, Maxim Y. Gorbunov, Steven J. Ludtke, Paul G. Falkowski, and Wei Dai [Generalized size scaling of metabolic rates based on single-cell measurements with freshwater phytoplankton]( Silvia Zaoli, Andrea Giometto, Emilio Marañón, Stéphane Escrig, Anders Meibom, Arti Ahluwalia, Roman Stocker, Amos Maritan, and Andrea Rinaldo [Controlling the material properties and rRNA processing function of the nucleolus using light]( Lian Zhu, Tiffany M. Richardson, Ludivine Wacheul, Ming-Tzo Wei, Marina Feric, Gena Whitney, Denis L. J. Lafontaine, and Clifford P. Brangwynne [Spreading of perturbations in myosin group kinetics along actin filaments]( Zsombor Balassy, Anne-Marie Lauzon, and Lennart Hilbert [Mutation of external glutamate residue reveals a new intermediate transport state and anion binding site in a CLC Cl−/H+ antiporter]( Kunwoong Park, Byoung-Cheol Lee, and Hyun-Ho Lim Cell Biology [Autophosphorylation is sufficient to release Mps1 kinase from native kinetochores]( Lori B. Koch, Kwaku N. Opoku, Yi Deng, Adrienne Barber, Aimee J. Littleton, Nitobe London, Sue Biggins, and Charles L. Asbury [Single-cell RNA-seq identifies a reversible mesodermal activation in abnormally specified epithelia of p63 EEC syndrome]( Eduardo Soares, Quan Xu, Qingqing Li, Jieqiong Qu, Yuxuan Zheng, Henriette H. M. Raeven, Karina O. Brandao, Isabelle Petit, Willem M. R. van den Akker, Simon J. van Heeringen, Daniel Aberdam, Fuchou Tang, and Huiqing Zhou Ecology [Mesoscale eddies release pelagic sharks from thermal constraints to foraging in the ocean twilight zone]( Camrin D. Braun, Peter Gaube, Tane H. Sinclair-Taylor, Gregory B. Skomal, and Simon R. Thorrold [Biomass losses resulting from insect and disease invasions in US forests]( Songlin Fei, Randall S. Morin, Christopher M. Oswalt, and Andrew M. Liebhold Genetics [Essential Saccharomyces cerevisiae genome instability suppressing genes identify potential human tumor suppressors]( Anjana Srivatsan, Binzhong Li, Dafne N. Sanchez, Steven B. Somach, Vandeclecio L. da Silva, Sandro J. de Souza, Christopher D. Putnam, and Richard D. Kolodner [Dietary restriction improves proteostasis and increases life span through endoplasmic reticulum hormesis]( Latika Matai, Gautam Chandra Sarkar, Manish Chamoli, Yasir Malik, Shashi Shekhar Kumar, Umanshi Rautela, Nihar Ranjan Jana, Kausik Chakraborty, and Arnab Mukhopadhyay Immunology and Inflammation [A dynamical motif comprising the interactions between antigens and CD8 T cells may underlie the outcomes of viral infections]( Subhasish Baral, Rustom Antia, and Narendra M. Dixit [An influenza virus-triggered SUMO switch orchestrates co-opted endogenous retroviruses to stimulate host antiviral immunity]( Nora Schmidt, Patricia Domingues, Filip Golebiowski, Corinna Patzina, Michael H. Tatham, Ronald T. Hay, and Benjamin G. Hale [IL-17 constrains natural killer cell activity by restraining IL-15–driven cell maturation via SOCS3]( Xuefu Wang, Rui Sun, Xiaolei Hao, Zhe-Xiong Lian, Haiming Wei, and Zhigang Tian [Intrinsic expression of viperin regulates thermogenesis in adipose tissues]( John Eom, Jeong Jin Kim, Seul Gi Yoon, Haengdueng Jeong, Soojin Son, Jae Bong Lee, Jihye Yoo, Hyun Ju Seo, Yejin Cho, Ku Sul Kim, Kyung Mi Choi, Il Yong Kim, Hui-Young Lee, Ki Taek Nam, Peter Cresswell, Je Kyung Seong, and Jun-Young Seo Medical Sciences [Transient enhancement of p53 activity protects from radiation-induced gastrointestinal toxicity]( Vinod Pant, Shunbin Xiong, Amanda R. Wasylishen, Connie A. Larsson, Neeraj K. Aryal, Gilda Chau, Ramesh C. Tailor, and Guillermina Lozano [MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers]( Gayathri Srinivasan, Elizabeth A. Williamson, Kimi Kong, Aruna S. Jaiswal, Guangcun Huang, Hyun-Suk Kim, Orlando Schärer, Weixing Zhao, Sandeep Burma, Patrick Sung, and Robert Hromas [Histone H4 induces platelet ballooning and microparticle release during trauma hemorrhage]( Paul Vulliamy, Scarlett Gillespie, Paul C. Armstrong, Harriet E. Allan, Timothy D. Warner, and Karim Brohi [ARF6 and AMAP1 are major targets of KRAS and TP53 mutations to promote invasion, PD-L1 dynamics, and immune evasion of pancreatic cancer]( Shigeru Hashimoto, Shotaro Furukawa, Ari Hashimoto, Akio Tsutaho, Akira Fukao, Yurika Sakamura, Gyanu Parajuli, Yasuhito Onodera, Yutaro Otsuka, Haruka Handa, Tsukasa Oikawa, Soichiro Hata, Yoshihiro Nishikawa, Yusuke Mizukami, Yuzo Kodama, Masaaki Murakami, Toshinobu Fujiwara, Satoshi Hirano, and Hisataka Sabe [Enhanced adaptive immune responses in lung adenocarcinoma through natural killer cell stimulation]( Leah Schmidt, Banu Eskiocak, Ryan Kohn, Celeste Dang, Nikhil S. Joshi, Michel DuPage, Da-Yae Lee, and Tyler Jacks [iASPP mediates p53 selectivity through a modular mechanism fine-tuning DNA recognition]( Shuo Chen, Jiale Wu, Shan Zhong, Yuntong Li, Ping Zhang, Jingyi Ma, Jingshan Ren, Yun Tan, Yunhao Wang, Kin Fai Au, Christian Siebold, Gareth L. Bond, Zhu Chen, Min Lu, E. Yvonne Jones, and Xin Lu Microbiology [Toxoplasma gondii effector TgIST blocks type I interferon signaling to promote infection]( Sumit K. Matta, Philipp Olias, Zhou Huang, Qiuling Wang, Eugene Park, Wayne M. Yokoyama, and L. David Sibley [Alternative promoters drive human cytomegalovirus reactivation from latency]( Donna Collins-McMillen, Mike Rak, Jason C. Buehler, Suzu Igarashi-Hayes, Jeremy P. Kamil, Nathaniel J. Moorman, and Felicia Goodrum [Role of a patatin-like phospholipase in Plasmodium falciparum gametogenesis and malaria transmission]( Pallavi Singh, Aditi Alaganan, Kunal R. More, Audrey Lorthiois, Sabine Thiberge, Olivier Gorgette, Micheline Guillotte Blisnick, Julien Guglielmini, Shivani Shankar Aguilera, Lhousseine Touqui, Shailja Singh, and Chetan E. Chitnis Neuroscience [Learning active sensing strategies using a sensory brain–machine interface]( Andrew G. Richardson, Yohannes Ghenbot, Xilin Liu, Han Hao, Cole Rinehart, Sam DeLuccia, Solymar Torres Maldonado, Gregory Boyek, Milin Zhang, Firooz Aflatouni, Jan Van der Spiegel, and Timothy H. Lucas [Human GNPTAB stuttering mutations engineered into mice cause vocalization deficits and astrocyte pathology in the corpus callosum]( Tae-Un Han, Jessica Root, Laura D. Reyes, Elizabeth B. Huchinson, Johann du Hoffmann, Wang-Sik Lee, Terra D. Barnes, and Dennis Drayna Pharmacology [Structure and dynamics of G protein-coupled receptor–bound ghrelin reveal the critical role of the octanoyl chain]( Guillaume Ferré, Maxime Louet, Oliver Saurel, Bartholomé Delort, Georges Czaplicki, Céline M’Kadmi, Marjorie Damian, Pedro Renault, Sonia Cantel, Laurent Gavara, Pascal Demange, Jacky Marie, Jean-Alain Fehrentz, Nicolas Floquet, Alain Milon, and Jean-Louis Banères [Upregulation of reduced folate carrier by vitamin D enhances brain folate uptake in mice lacking folate receptor alpha]( Camille Alam, Susanne Aufreiter, Constantine J. Georgiou, Md. Tozammel Hoque, Richard H. Finnell, Deborah L. O’Connor, I. David Goldman, and Reina Bendayan Physiology [Akt phosphorylation of neuronal nitric oxide synthase regulates gastrointestinal motility in mouse ileum]( Damian D. Guerra, Rachael Bok, Vibhuti Vyas, David J. Orlicky, Ramón A. Lorca, and K. Joseph Hurt [Piezo2 integrates mechanical and thermal cues in vertebrate mechanoreceptors]( Wang Zheng, Yury A. Nikolaev, Elena O. Gracheva, and Sviatoslav N. Bagriantsev Plant Biology [Regulation of photoprotection gene expression in Chlamydomonas by a putative E3 ubiquitin ligase complex and a homolog of CONSTANS]( Stéphane T. Gabilly, Christopher R. Baker, Setsuko Wakao, Thien Crisanto, Katharine Guan, Ke Bi, Elodie Guiet, Carmela R. Guadagno, and Krishna K. Niyogi [The catalytic core of DEMETER guides active DNA demethylation in Arabidopsis]( Changqing Zhang, Yu-Hung Hung, Hyun Jung Rim, Dapeng Zhang, Jennifer M. Frost, Hosub Shin, Hosung Jang, Fang Liu, Wenyan Xiao, Lakshminarayan M. Iyer, L. Aravind, Xiang-Qian Zhang, Robert L. Fischer, Jin Hoe Huh, and Tzung-Fu Hsieh [Phosphorylation-guarded light-harvesting complex II contributes to broad-spectrum blast resistance in rice]( Muxing Liu, Suobing Zhang, Jiexiong Hu, Wenxian Sun, Jonas Padilla, Yanglan He, Ying Li, Ziyi Yin, Xinyu Liu, Wenhao Wang, Danyu Shen, Dayong Li, Haifeng Zhang, Xiaobo Zheng, Zhongli Cui, Guo-Liang Wang, Ping Wang, Bo Zhou, and Zhengguang Zhang [Dynamic regulation of chromatin topology and transcription by inverted repeat-derived small RNAs in sunflower]( Delfina Gagliardi, Damian A. Cambiagno, Agustin L. Arce, Ariel H. Tomassi, Jorge I. Giacomelli, Federico D. Ariel, and Pablo A. Manavella [Arabidopsis BRUTUS-LIKE E3 ligases negatively regulate iron uptake by targeting transcription factor FIT for recycling]( Jorge Rodríguez-Celma, James M. Connorton, Inga Kruse, Robert T. Green, Marina Franceschetti, Yi-Tze Chen, Yan Cui, Hong-Qing Ling, Kuo-Chen Yeh, and Janneke Balk Systems Biology [Energy metabolism controls phenotypes by protein efficiency and allocation]( Yu Chen and Jens Nielsen --------------------------------------------------------------- Corrections [Correction for Piccardo et al., Radio frequency transmitter based on a laser frequency comb]( [Correction for Wu et al., Wettability effect on nanoconfined water flow]( [Correction for Shpigler et al., Deep evolutionary conservation of autism-related genes]( [Correction for Yang et al., Leveraging abscisic acid receptors for efficient water use in Arabidopsis]( [Cover] --------------------------------------------------------------- This message was sent to {EMAIL}. [Unsubscribe]( from or [edit]( your subscription for this service. Or by mail: Customer Service * 973 University Avenue * Los Gatos, CA 95032 * U.S.A. Copyright © 2019 by the National Academy of Sciences