PNAS Table of Contents for March 5, 2019; Vol. 116, No. 10

[PNAS] [Listen to the latest PNAS Podcast.](/cgi/adclick/?ad=53581&adclick=true&url=http%3A%2F%2Fwww.pnas.org%2Fpage%2Fmedia%2Fpodcasts)   [March 5, 2019; Vol. 116, No. 10]( ) This Week in PNAS [In This Issue]( --------------------------------------------------------------- Letters [Capturing the multiplicative effect of perseverance and passion: Measurement issues of combining two grit facets]( Jiesi Guo, Xin Tang, and Kate M. Xu [Total grit scale score does not represent perseverance]( Marcus Credé [Reply to Guo et al. and Credé: Grit-S scale measures only perseverance, not passion, and its supposed subfactors are merely artifactors]( Jon M. Jachimowicz, Andreas Wihler, Erica R. Bailey, and Adam D. Galinsky [SNPs deciding the rapid growth of cyanobacteria are alterable]( Jie Zhou and Yin Li [Reply to Zhou and Li: Plasticity of the genomic haplotype of Synechococcus elongatus leads to rapid strain adaptation under laboratory conditions]( Justin Ungerer, Kristen E. Wendt, John I. Hendry, Costas D. Maranas, and Himadri B. Pakrasi --------------------------------------------------------------- Opinion [Opinion: Why science needs philosophy]( Lucie Laplane, Paolo Mantovani, Ralph Adolphs, Hasok Chang, Alberto Mantovani, Margaret McFall-Ngai, Carlo Rovelli, Elliott Sober, and Thomas Pradeu Leading scientists discuss current issues. --------------------------------------------------------------- Commentaries [Artificial intelligence to support human instruction]( Michael C. Mozer, Melody Wiseheart, and Timothy P. Novikoff [Turbine enzyme’s structure in the crosshairs to target tuberculosis]( Thomas M. Duncan [Nucleotide-dependent conformational changes in the actin filament: Subtler than expected]( Roberto Dominguez [Forest age improves understanding of the global carbon sink]( Kai Zhu, Yiluan Song, and Clara Qin [Blockade of RAF and autophagy is the one-two punch to take out Ras]( Eileen White --------------------------------------------------------------- Physical Sciences Applied Mathematics [Fate mapping reveals the age structure of the peripheral T cell compartment]( Arnold Reynaldi, Norah L. Smith, Timothy E. Schlub, Cybelle Tabilas, Vanessa Venturi, Brian D. Rudd, and Miles P. Davenport [Statistical dynamical model to predict extreme events and anomalous features in shallow water waves with abrupt depth change]( Andrew J. Majda, M. N. J. Moore, and Di Qi [Enhancing human learning via spaced repetition optimization]( Behzad Tabibian, Utkarsh Upadhyay, Abir De, Ali Zarezade, Bernhard Schölkopf, and Manuel Gomez-Rodriguez Applied Physical Sciences [Multimillijoule coherent terahertz bursts from picosecond laser-irradiated metal foils]( Guoqian Liao, Yutong Li, Hao Liu, Graeme G. Scott, David Neely, Yihang Zhang, Baojun Zhu, Zhe Zhang, Chris Armstrong, Egle Zemaityte, Philip Bradford, Peter G. Huggard, Dean R. Rusby, Paul McKenna, Ceri M. Brenner, Nigel C. Woolsey, Weimin Wang, Zhengming Sheng, and Jie Zhang [Linking plasma formation in grapes to microwave resonances of aqueous dimers]( Hamza K. Khattak, Pablo Bianucci, and Aaron D. Slepkov [Observation of chiral surface excitons in a topological insulator Bi2Se3]( H.-H. Kung, A. P. Goyal, D. L. Maslov, X. Wang, A. Lee, A. F. Kemper, S.-W. Cheong, and G. Blumberg [Amyloid fibril-directed synthesis of silica core–shell nanofilaments, gels, and aerogels]( Yiping Cao, Sreenath Bolisetty, Gianna Wolfisberg, Jozef Adamcik, and Raffaele Mezzenga [Three-dimensional optical trapping and orientation of microparticles for coherent X-ray diffraction imaging]( Yuan Gao, Ross Harder, Stephen H. Southworth, Jeffrey R. Guest, Xiaojing Huang, Zijie Yan, Leonidas E. Ocola, Yuval Yifat, Nishant Sule, Phay J. Ho, Matthew Pelton, Norbert F. Scherer, and Linda Young Biophysics and Computational Biology [Five computational developability guidelines for therapeutic antibody profiling]( Matthew I. J. Raybould, Claire Marks, Konrad Krawczyk, Bruck Taddese, Jaroslaw Nowak, Alan P. Lewis, Alexander Bujotzek, Jiye Shi, and Charlotte M. Deane [Diblock copolymers enhance folding of a mechanosensitive membrane protein during cell-free expression]( Miranda L. Jacobs, Margrethe A. Boyd, and Neha P. Kamat [Local frustration around enzyme active sites]( Maria I. Freiberger, A. Brenda Guzovsky, Peter G. Wolynes, R. Gonzalo Parra, and Diego U. Ferreiro Chemistry [Biosynthesis of magnetic nanoparticles from nano-degradation products revealed in human stem cells]( Aurore Van de Walle, Anouchka Plan Sangnier, Ali Abou-Hassan, Alberto Curcio, Miryana Hémadi, Nicolas Menguy, Yoann Lalatonne, Nathalie Luciani, and Claire Wilhelm [Microscopic description of acid–base equilibrium]( Emanuele Grifoni, GiovanniMaria Piccini, and Michele Parrinello [Compatibility of quantitative X-ray spectroscopy with continuous distribution models of water at ambient conditions]( Johannes Niskanen, Mattis Fondell, Christoph J. Sahle, Sebastian Eckert, Raphael M. Jay, Keith Gilmore, Annette Pietzsch, Marcus Dantz, Xingye Lu, Daniel E. McNally, Thorsten Schmitt, Vinicius Vaz da Cruz, Victor Kimberg, Faris Gel’mukhanov, and Alexander Föhlisch [Single-molecule excitation–emission spectroscopy]( Erling Thyrhaug, Stefan Krause, Antonio Perri, Giulio Cerullo, Dario Polli, Tom Vosch, and Jürgen Hauer [Probing the link between residual entropy and viscosity of molecular fluids and model potentials]( Ian H. Bell [Generalizing the effects of chirality on block copolymer assembly]( Hsiao-Fang Wang, Kai-Chieh Yang, Wen-Chun Hsu, Jing-Yu Lee, Jung-Tzu Hsu, Gregory M. Grason, Edwin L. Thomas, Jing-Cherng Tsai, and Rong-Ming Ho [Self-assembled ruthenium (II) metallacycles and metallacages with imidazole-based ligands and their in vitro anticancer activity]( Yibo Zhao, Liqian Zhang, Xu Li, Yanhui Shi, Ruru Ding, Mengting Teng, Peng Zhang, Changsheng Cao, and Peter J. Stang Earth, Atmospheric, and Planetary Sciences [Impact of abrupt sea ice loss on Greenland water isotopes during the last glacial period]( Louise C. Sime, Peter O. Hopcroft, and Rachael H. Rhodes [Changing available energy for extratropical cyclones and associated convection in Northern Hemisphere summer]( Charles G. Gertler and Paul A. O’Gorman [Form and function of F-actin during biomineralization revealed from live experiments on foraminifera]( Jarosław Tyszka, Ulf Bickmeyer, Markus Raitzsch, Jelle Bijma, Karina Kaczmarek, Antje Mewes, Paweł Topa, and Max Janse [Trilobite evolutionary rates constrain the duration of the Cambrian explosion]( John R. Paterson, Gregory D. Edgecombe, and Michael S. Y. Lee Engineering [From 2D to 3D: Strain- and elongation-free topological transformations of optoelectronic circuits]( Dejiu Fan, Byungjun Lee, Caleb Coburn, and Stephen R. Forrest [Deep elastic strain engineering of bandgap through machine learning]( Zhe Shi, Evgenii Tsymbalov, Ming Dao, Subra Suresh, Alexander Shapeev, and Ju Li [Solving matrix equations in one step with cross-point resistive arrays]( Zhong Sun, Giacomo Pedretti, Elia Ambrosi, Alessandro Bricalli, Wei Wang, and Daniele Ielmini [Beating the reaction limits of biosensor sensitivity with dynamic tracking of single binding events]( Derin Sevenler, Jacob Trueb, and M. Selim Ünlü [Mobile platform for rapid sub–picogram-per-milliliter, multiplexed, digital droplet detection of proteins]( Venkata Yelleswarapu, Joshua R. Buser, Margalit Haber, Jonathan Baron, Eshwar Inapuri, and David Issadore Physics [Unraveling materials Berry curvature and Chern numbers from real-time evolution of Bloch states]( Dongbin Shin, Shunsuke A. Sato, Hannes Hübener, Umberto De Giovannini, Jeongwoo Kim, Noejung Park, and Angel Rubio [Observing a previously hidden structural-phase transition onset through heteroepitaxial cap response]( Fanli Lan, Hongyan Chen, Hanxuan Lin, Yu Bai, Yang Yu, Tian Miao, Yinyan Zhu, T. Z. Ward, Zheng Gai, Wenbin Wang, Lifeng Yin, E. W. Plummer, and Jian Shen [Quantum experiments and graphs II: Quantum interference, computation, and state generation]( Xuemei Gu, Manuel Erhard, Anton Zeilinger, and Mario Krenn Statistics [Metalearners for estimating heterogeneous treatment effects using machine learning]( Sören R. Künzel, Jasjeet S. Sekhon, Peter J. Bickel, and Bin Yu Sustainability Science [Crop variety management for climate adaptation supported by citizen science]( Jacob van Etten, Kauê de Sousa, Amílcar Aguilar, Mirna Barrios, Allan Coto, Matteo Dell’Acqua, Carlo Fadda, Yosef Gebrehawaryat, Jeske van de Gevel, Arnab Gupta, Afewerki Y. Kiros, Brandon Madriz, Prem Mathur, Dejene K. Mengistu, Leida Mercado, Jemal Nurhisen Mohammed, Ambica Paliwal, Mario Enrico Pè, Carlos F. Quirós, Juan Carlos Rosas, Neeraj Sharma, S. S. Singh, Iswhar S. Solanki, and Jonathan Steinke --------------------------------------------------------------- Social Sciences Anthropology [Genomic evidence for shared common ancestry of East African hunting-gathering populations and insights into local adaptation]( Laura B. Scheinfeldt, Sameer Soi, Charla Lambert, Wen-Ya Ko, Aoua Coulibaly, Alessia Ranciaro, Simon Thompson, Jibril Hirbo, William Beggs, Muntaser Ibrahim, Thomas Nyambo, Sabah Omar, Dawit Woldemeskel, Gurja Belay, Alain Froment, Junhyong Kim, and Sarah A. Tishkoff Political Sciences [Metalearners for estimating heterogeneous treatment effects using machine learning]( Sören R. Künzel, Jasjeet S. Sekhon, Peter J. Bickel, and Bin Yu Psychological and Cognitive Sciences [Emergence of analogy from relation learning]( Hongjing Lu, Ying Nian Wu, and Keith J. Holyoak [Self-regulation and the foraging gene (PRKG1) in humans]( Andriy A. Struk, Jhotisha Mugon, Andrea Huston, Abigail A. Scholer, Gertraud Stadler, E. Tory Higgins, Marla B. Sokolowski, and James Danckert [The nature of recollection across months and years and after medial temporal lobe damage]( Nadine C. Heyworth and Larry R. Squire [Cortical route for facelike pattern processing in human newborns]( Marco Buiatti, Elisa Di Giorgio, Manuela Piazza, Carlo Polloni, Giuseppe Menna, Fabrizio Taddei, Ermanno Baldo, and Giorgio Vallortigara [Social threat learning transfers to decision making in humans]( Björn Lindström, Armita Golkar, Simon Jangard, Philippe N. Tobler, and Andreas Olsson Social Sciences [The changing career trajectories of new parents in STEM]( Erin A. Cech and Mary Blair-Loy Sustainability Science [Defining the economic scope for ecosystem-based fishery management]( Kailin Kroetz, Matthew N. Reimer, James N. Sanchirico, Daniel K. Lew, and Justine Huetteman --------------------------------------------------------------- Biological Sciences Agricultural Sciences [Crop variety management for climate adaptation supported by citizen science]( Jacob van Etten, Kauê de Sousa, Amílcar Aguilar, Mirna Barrios, Allan Coto, Matteo Dell’Acqua, Carlo Fadda, Yosef Gebrehawaryat, Jeske van de Gevel, Arnab Gupta, Afewerki Y. Kiros, Brandon Madriz, Prem Mathur, Dejene K. Mengistu, Leida Mercado, Jemal Nurhisen Mohammed, Ambica Paliwal, Mario Enrico Pè, Carlos F. Quirós, Juan Carlos Rosas, Neeraj Sharma, S. S. Singh, Iswhar S. Solanki, and Jonathan Steinke Applied Biological Sciences [Egg-based influenza split virus vaccine with monoglycosylation induces cross-strain protection against influenza virus infections]( Yung-Chieh Tseng, Chia-Yu Wu, Ming-Liang Liu, Ting-Hua Chen, Wan-Ling Chiang, Yueh-Hsiang Yu, Jia-Tsrong Jan, Kuo-I Lin, Chi-Huey Wong, and Che Ma Biochemistry [The structure of the catalytic domain of the ATP synthase from Mycobacterium smegmatis is a target for developing antitubercular drugs]( Alice Tianbu Zhang, Martin G. Montgomery, Andrew G. W. Leslie, Gregory M. Cook, and John E. Walker [LHCSR3 is a nonphotochemical quencher of both photosystems in Chlamydomonas reinhardtii]( Laura Girolomoni, Stefano Cazzaniga, Alberta Pinnola, Federico Perozeni, Matteo Ballottari, and Roberto Bassi [Phosphoregulated FMRP phase separation models activity-dependent translation through bidirectional control of mRNA granule formation]( Brian Tsang, Jason Arsenault, Robert M. Vernon, Hong Lin, Nahum Sonenberg, Lu-Yang Wang, Alaji Bah, and Julie D. Forman-Kay [26S Proteasomes are rapidly activated by diverse hormones and physiological states that raise cAMP and cause Rpn6 phosphorylation]( Jordan J. S. VerPlank, Sudarsanareddy Lokireddy, Jinghui Zhao, and Alfred L. Goldberg Biophysics and Computational Biology [Structural basis for activity of TRIC counter-ion channels in calcium release]( Xiao-hui Wang, Min Su, Feng Gao, Wenjun Xie, Yang Zeng, De-lin Li, Xue-lei Liu, Hong Zhao, Li Qin, Fei Li, Qun Liu, Oliver B. Clarke, Sin Man Lam, Guang-hou Shui, Wayne A. Hendrickson, and Yu-hang Chen [Atomic-level characterization of protein–protein association]( Albert C. Pan, Daniel Jacobson, Konstantin Yatsenko, Duluxan Sritharan, Thomas M. Weinreich, and David E. Shaw [Dimers of mitochondrial ATP synthase induce membrane curvature and self-assemble into rows]( Thorsten B. Blum, Alexander Hahn, Thomas Meier, Karen M. Davies, and Werner Kühlbrandt [Assembly and cryo-EM structures of RNA-specific measles virus nucleocapsids provide mechanistic insight into paramyxoviral replication]( Ambroise Desfosses, Sigrid Milles, Malene Ringkjøbing Jensen, Serafima Guseva, Jacques-Philippe Colletier, Damien Maurin, Guy Schoehn, Irina Gutsche, Rob W. H. Ruigrok, and Martin Blackledge [Mechanism of actin polymerization revealed by cryo-EM structures of actin filaments with three different bound nucleotides]( Steven Z. Chou and Thomas D. Pollard [Nanometer-accuracy distance measurements between fluorophores at the single-molecule level]( Stefan Niekamp, Jongmin Sung, Walter Huynh, Gira Bhabha, Ronald D. Vale, and Nico Stuurman Cell Biology [Biosynthesis of magnetic nanoparticles from nano-degradation products revealed in human stem cells]( Aurore Van de Walle, Anouchka Plan Sangnier, Ali Abou-Hassan, Alberto Curcio, Miryana Hémadi, Nicolas Menguy, Yoann Lalatonne, Nathalie Luciani, and Claire Wilhelm [PGC1A regulates the IRS1:IRS2 ratio during fasting to influence hepatic metabolism downstream of insulin]( Aurèle Besse-Patin, Stewart Jeromson, Philipa Levesque-Damphousse, Blandine Secco, Mathieu Laplante, and Jennifer L. Estall [Tissue self-organization based on collective cell migration by contact activation of locomotion and chemotaxis]( Taihei Fujimori, Akihiko Nakajima, Nao Shimada, and Satoshi Sawai [A mechanism for temporary bioadhesion]( Julia Wunderer, Birgit Lengerer, Robert Pjeta, Philip Bertemes, Leopold Kremser, Herbert Lindner, Thomas Ederth, Michael W. Hess, David Stock, Willi Salvenmoser, and Peter Ladurner [Concentric organization of A- and B-type lamins predicts their distinct roles in the spatial organization and stability of the nuclear lamina]( Bruce Nmezi, Jianquan Xu, Rao Fu, Travis J. Armiger, Guillermo Rodriguez-Bey, Juliana S. Powell, Hongqiang Ma, Mara Sullivan, Yiping Tu, Natalie Y. Chen, Stephen G. Young, Donna B. Stolz, Kris Noel Dahl, Yang Liu, and Quasar S. Padiath [Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase]( Michaela Kunova Bosakova, Alexandru Nita, Tomas Gregor, Miroslav Varecha, Iva Gudernova, Bohumil Fafilek, Tomas Barta, Neha Basheer, Sara P. Abraham, Lukas Balek, Marketa Tomanova, Jana Fialova Kucerova, Juraj Bosak, David Potesil, Jennifer Zieba, Jieun Song, Peter Konik, Sohyun Park, Ivan Duran, Zbynek Zdrahal, David Smajs, Gert Jansen, Zheng Fu, Hyuk Wan Ko, Ales Hampl, Lukas Trantirek, Deborah Krakow, and Pavel Krejci [Reactive oxygen species modulate macrophage immunosuppressive phenotype through the up-regulation of PD-L1]( Cecilia Roux, Soode Moghadas Jafari, Rahul Shinde, Gordon Duncan, David W. Cescon, Jennifer Silvester, Mandy F. Chu, Kelsey Hodgson, Thorsten Berger, Andrew Wakeham, Luis Palomero, Mar Garcia-Valero, Miguel A. Pujana, Tak W. Mak, Tracy L. McGaha, Paola Cappello, and Chiara Gorrini [Early onset preeclampsia in a model for human placental trophoblast]( Megan A. Sheridan, Ying Yang, Ashish Jain, Alex S. Lyons, Penghua Yang, Sambasiva R. Brahmasani, Aihua Dai, Yuchen Tian, Mark R. Ellersieck, Geetu Tuteja, Danny J. Schust, Laura C. Schulz, Toshihiko Ezashi, and R. Michael Roberts Developmental Biology [Pluripotent stem cell-derived myogenic progenitors remodel their molecular signature upon in vivo engraftment]( Tania Incitti, Alessandro Magli, Radbod Darabi, Ce Yuan, Karena Lin, Robert W. Arpke, Karim Azzag, Ami Yamamoto, Ron Stewart, James A. Thomson, Michael Kyba, and Rita C. R. Perlingeiro [Coupling between dynamic 3D tissue architecture and BMP morphogen signaling during Drosophila wing morphogenesis]( Jinghua Gui, Yunxian Huang, Martin Montanari, Daniel Toddie-Moore, Kenji Kikushima, Stephanie Nix, Yukitaka Ishimoto, and Osamu Shimmi [Early lineage specification defines alveolar epithelial ontogeny in the murine lung]( David B. Frank, Ian J. Penkala, Jarod A. Zepp, Aravind Sivakumar, Ricardo Linares-Saldana, William J. Zacharias, Katharine G. Stolz, Josh Pankin, MinQi Lu, Qiaohong Wang, Apoorva Babu, Li Li, Su Zhou, Michael P. Morley, Rajan Jain, and Edward E. Morrisey Ecology [Experimental support for alternative attractors on coral reefs]( Russell J. Schmitt, Sally J. Holbrook, Samantha L. Davis, Andrew J. Brooks, and Thomas C. Adam Environmental Sciences [Role of forest regrowth in global carbon sink dynamics]( Thomas A. M. Pugh, Mats Lindeskog, Benjamin Smith, Benjamin Poulter, Almut Arneth, Vanessa Haverd, and Leonardo Calle [Photosynthetic adaptation to low iron, light, and temperature in Southern Ocean phytoplankton]( Robert F. Strzepek, Philip W. Boyd, and William G. Sunda Evolution [Trilobite evolutionary rates constrain the duration of the Cambrian explosion]( John R. Paterson, Gregory D. Edgecombe, and Michael S. Y. Lee [Molecular mechanism and history of non-sense to sense evolution of antifreeze glycoprotein gene in northern gadids]( Xuan Zhuang, Chun Yang, Katherine R. Murphy, and C.-H. Christina Cheng [Extreme diversification of floral volatiles within and among species of Lithophragma (Saxifragaceae)]( Magne Friberg, Christopher Schwind, Paulo R. Guimarães Jr., Robert A. Raguso, and John N. Thompson [Lateral transfers of large DNA fragments spread functional genes among grasses]( Luke T. Dunning, Jill K. Olofsson, Christian Parisod, Rimjhim Roy Choudhury, Jose J. Moreno-Villena, Yang Yang, Jacqueline Dionora, W. Paul Quick, Minkyu Park, Jeffrey L. Bennetzen, Guillaume Besnard, Patrik Nosil, Colin P. Osborne, and Pascal-Antoine Christin [Evolution of resilience in protein interactomes across the tree of life]( Marinka Zitnik, Rok Sosič, Marcus W. Feldman, and Jure Leskovec Genetics [Self-regulation and the foraging gene (PRKG1) in humans]( Andriy A. Struk, Jhotisha Mugon, Andrea Huston, Abigail A. Scholer, Gertraud Stadler, E. Tory Higgins, Marla B. Sokolowski, and James Danckert [Processing generates 3′ ends of RNA masking transcription termination events in prokaryotes]( Xun Wang, Monford Paul Abishek N, Heung Jin Jeon, Yonho Lee, Jin He, Sankar Adhya, and Heon M. Lim [White shark genome reveals ancient elasmobranch adaptations associated with wound healing and the maintenance of genome stability]( Nicholas J. Marra, Michael J. Stanhope, Nathaniel K. Jue, Minghui Wang, Qi Sun, Paulina Pavinski Bitar, Vincent P. Richards, Aleksey Komissarov, Mike Rayko, Sergey Kliver, Bryce J. Stanhope, Chuck Winkler, Stephen J. O’Brien, Agostinho Antunes, Salvador Jorgensen, and Mahmood S. Shivji Immunology and Inflammation [Fate mapping reveals the age structure of the peripheral T cell compartment]( Arnold Reynaldi, Norah L. Smith, Timothy E. Schlub, Cybelle Tabilas, Vanessa Venturi, Brian D. Rudd, and Miles P. Davenport [Role for nuclear interleukin-37 in the suppression of innate immunity]( Suzhao Li, Jesus Amo-Aparicio, Charles P. Neff, Isak W. Tengesdal, Tania Azam, Brent E. Palmer, Rubèn López-Vales, Philip Bufler, and Charles A. Dinarello [Pivotal role for αV integrins in sustained Tfh support of the germinal center response for long-lived plasma cell generation]( Dillon C. Schrock, Scott A. Leddon, Angela Hughson, Jim Miller, Adam Lacy-Hulbert, and Deborah J. Fowell [E-protein regulatory network links TCR signaling to effector Treg cell differentiation]( Xiaojuan Han, Huarong Huang, Ping Gao, Qi Zhang, Xinyuan Liu, Baoqian Jia, Warren Strober, Baidong Hou, Xuyu Zhou, George Fu Gao, and Fuping Zhang [CD4+ T help promotes influenza virus-specific CD8+ T cell memory by limiting metabolic dysfunction]( Jolie G. Cullen, Hayley A. McQuilten, Kylie M. Quinn, Moshe Olshansky, Brendan E. Russ, Alison Morey, Sanna Wei, Julia E. Prier, Nicole L. La Gruta, Peter C. Doherty, and Stephen J. Turner Medical Sciences [Mobile platform for rapid sub–picogram-per-milliliter, multiplexed, digital droplet detection of proteins]( Venkata Yelleswarapu, Joshua R. Buser, Margalit Haber, Jonathan Baron, Eshwar Inapuri, and David Issadore [Dual AAV-mediated gene therapy restores hearing in a DFNB9 mouse model]( Omar Akil, Frank Dyka, Charlotte Calvet, Alice Emptoz, Ghizlene Lahlou, Sylvie Nouaille, Jacques Boutet de Monvel, Jean-Pierre Hardelin, William W. Hauswirth, Paul Avan, Christine Petit, Saaid Safieddine, and Lawrence R. Lustig [WNK4 kinase is a physiological intracellular chloride sensor]( Jen-Chi Chen, Yi-Fen Lo, Ya-Wen Lin, Shih-Hua Lin, Chou-Long Huang, and Chih-Jen Cheng [MAP kinase and autophagy pathways cooperate to maintain RAS mutant cancer cell survival]( Chih-Shia Lee, Liam C. Lee, Tina L. Yuan, Sirisha Chakka, Christof Fellmann, Scott W. Lowe, Natasha J. Caplen, Frank McCormick, and Ji Luo [Podocalyxin is required for maintaining blood–brain barrier function during acute inflammation]( Jessica Cait, Michael R. Hughes, Matthew R. Zeglinski, Allen W. Chan, Sabrina Osterhof, R. Wilder Scott, Diana Canals Hernaez, Alissa Cait, A. Wayne Vogl, Pascal Bernatchez, T. Michael Underhill, David J. Granville, Timothy H. Murphy, Calvin D. Roskelley, and Kelly M. McNagny [Ovarian insufficiency and CTNNB1 mutations drive malignant transformation of endometrial hyperplasia with altered PTEN/PI3K activities]( Jumpei Terakawa, Vanida Ann Serna, Makoto Mark Taketo, Takiko Daikoku, Adrian A. Suarez, and Takeshi Kurita [NOTCH1 signaling induces pathological vascular permeability in diabetic retinopathy]( Khalil Miloudi, Malika Oubaha, Catherine Ménard, Agnieszka Dejda, Vera Guber, Gael Cagnone, Ariel M. Wilson, Nicolas Tétreault, Gaëlle Mawambo, Francois Binet, Rony Chidiac, Chantal Delisle, Manuel Buscarlet, Agustin Cerani, Sergio Crespo-Garcia, Katie Bentley, Flavio Rezende, Jean-Sebastien Joyal, Frédérick A. Mallette, Jean-Philippe Gratton, Bruno Larrivée, and Przemyslaw Sapieha [Down-regulation of FZD3 receptor suppresses growth and metastasis of human melanoma independently of canonical WNT signaling]( Chen Li, Vincent Nguyen, Kaitlyn N. Clark, Tara Zahed, Shawn Sharkas, Fabian V. Filipp, and Alexander D. Boiko [Blocking CXCR4 alleviates desmoplasia, increases T-lymphocyte infiltration, and improves immunotherapy in metastatic breast cancer]( Ivy X. Chen, Vikash P. Chauhan, Jessica Posada, Mei R. Ng, Michelle W. Wu, Pichet Adstamongkonkul, Peigen Huang, Neal Lindeman, Robert Langer, and Rakesh K. Jain [Mouse and human urothelial cancer organoids: A tool for bladder cancer research]( Jasper Mullenders, Evelien de Jongh, Anneta Brousali, Mieke Roosen, Jan P. A. Blom, Harry Begthel, Jeroen Korving, Trudy Jonges, Onno Kranenburg, Richard Meijer, and Hans C. Clevers [Depletion of regulatory T cells in tumors with an anti-CD25 immunotoxin induces CD8 T cell-mediated systemic antitumor immunity]( Masanori Onda, Kazuto Kobayashi, and Ira Pastan [Loss of BOP1 confers resistance to BRAF kinase inhibitors in melanoma by activating MAP kinase pathway]( Romi Gupta, Suresh Bugide, Biao Wang, Michael R. Green, Douglas B. Johnson, and Narendra Wajapeyee [Anti-BCMA immunotoxins produce durable complete remissions in two mouse myeloma models]( Zoë Shancer, Xiu-fen Liu, Satoshi Nagata, Qi Zhou, Tapan K. Bera, and Ira Pastan Microbiology [Vibrio cholerae FeoB contains a dual nucleotide-specific NTPase domain essential for ferrous iron uptake]( Minhye Shin, Alexandra R. Mey, and Shelley M. Payne [A bacteria-based genetic assay detects prion formation]( Eleanor Fleming, Andy H. Yuan, Danielle M. Heller, and Ann Hochschild [H5N8 and H7N9 packaging signals constrain HA reassortment with a seasonal H3N2 influenza A virus]( Maria C. White, Hui Tao, John Steel, and Anice C. Lowen Neuroscience [The nature of recollection across months and years and after medial temporal lobe damage]( Nadine C. Heyworth and Larry R. Squire [Cortical route for facelike pattern processing in human newborns]( Marco Buiatti, Elisa Di Giorgio, Manuela Piazza, Carlo Polloni, Giuseppe Menna, Fabrizio Taddei, Ermanno Baldo, and Giorgio Vallortigara [Altered neural odometry in the vertical dimension]( Giulio Casali, Daniel Bush, and Kate Jeffery [Priming of microglia with IFN-γ slows neuronal gamma oscillations in situ]( Thuy-Truc Ta, Hasan Onur Dikmen, Simone Schilling, Bruno Chausse, Andrea Lewen, Jan-Oliver Hollnagel, and Oliver Kann [Role of UCHL1 in axonal injury and functional recovery after cerebral ischemia]( Hao Liu, Nadya Povysheva, Marie E. Rose, Zhiping Mi, Joseph S. Banton, Wenjin Li, Fenghua Chen, Daniel P. Reay, Germán Barrionuevo, Feng Zhang, and Steven H. Graham [Six6 and Six7 coordinately regulate expression of middle-wavelength opsins in zebrafish]( Yohey Ogawa, Tomoya Shiraki, Yoshimasa Asano, Akira Muto, Koichi Kawakami, Yutaka Suzuki, Daisuke Kojima, and Yoshitaka Fukada [Opposite regulation of Wnt/β-catenin and Shh signaling pathways by Rack1 controls mammalian cerebellar development]( Haihong Yang, Qian Zhu, Juanxian Cheng, Yan Wu, Ming Fan, Jiyan Zhang, and Haitao Wu [Role of the striatum in incidental learning of sound categories]( Sung-Joo Lim, Julie A. Fiez, and Lori L. Holt [Differential cortical microstructural maturation in the preterm human brain with diffusion kurtosis and tensor imaging]( Minhui Ouyang, Tina Jeon, Aristeidis Sotiras, Qinmu Peng, Virendra Mishra, Cathy Halovanic, Min Chen, Lina Chalak, Nancy Rollins, Timothy P. L. Roberts, Christos Davatzikos, and Hao Huang [Multimodal gradients across mouse cortex]( Ben D. Fulcher, John D. Murray, Valerio Zerbi, and Xiao-Jing Wang [Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects]( Joy Mitra, Erika N. Guerrero, Pavana M. Hegde, Nicole F. Liachko, Haibo Wang, Velmarini Vasquez, Junling Gao, Arvind Pandey, J. Paul Taylor, Brian C. Kraemer, Ping Wu, Istvan Boldogh, Ralph M. Garruto, Sankar Mitra, K. S. Rao, and Muralidhar L. Hegde Physiology [TRPM7 is the central gatekeeper of intestinal mineral absorption essential for postnatal survival]( Lorenz Mittermeier, Lusine Demirkhanyan, Benjamin Stadlbauer, Andreas Breit, Camilla Recordati, Anne Hilgendorff, Masayuki Matsushita, Attila Braun, David G. Simmons, Eleonora Zakharian, Thomas Gudermann, and Vladimir Chubanov Plant Biology [Mitochondrial small heat shock protein mediates seed germination via thermal sensing]( Wei Ma, Xueying Guan, Jie Li, Ronghui Pan, Luyao Wang, Fengjun Liu, Hongyu Ma, Shuijin Zhu, Jin Hu, Yong-Ling Ruan, Xiaoya Chen, and Tianzhen Zhang [Two E3 ligases antagonistically regulate the UV-B response in Arabidopsis]( Hui Ren, Jiupan Han, Panyu Yang, Weiwei Mao, Xin Liu, Leilei Qiu, Chongzhen Qian, Yan Liu, Zhiren Chen, Xinhao Ouyang, Xu Chen, Xing Wang Deng, and Xi Huang Psychological and Cognitive Sciences [Social threat learning transfers to decision making in humans]( Björn Lindström, Armita Golkar, Simon Jangard, Philippe N. Tobler, and Andreas Olsson Systems Biology [The global mass and average rate of rubisco]( Yinon M. Bar-On and Ron Milo --------------------------------------------------------------- Corrections [Correction for Rentoft et al., Heterozygous colon cancer-associated mutations of SAMHD1 have functional significance]( [Correction for Bloomfield et al., Triparental inheritance in Dictyostelium]( [Correction for Copin et al., Sequential evolution of virulence and resistance during clonal spread of community-acquired methicillin-resistant Staphylococcus aureus]( [Correction for Giguère-Croteau et al., North America’s oldest boreal trees are more efficient water users due to increased [CO2], but do not grow faster]( [Cover] --------------------------------------------------------------- This message was sent to {EMAIL}. [Unsubscribe]( from or [edit]( your subscription for this service. Or by mail: Customer Service * 973 University Avenue * Los Gatos, CA 95032 * U.S.A. Copyright © 2019 by the National Academy of Sciences