PNAS Table of Contents for 16 January 2018; Vol. 115, No. 3

[PNAS][Proceedings of the National Academy of Sciences] /content/current/content/multimedia/site/authors/index.xhtml/site/aboutpnas/index.xhtml/site/misc/collectedpapers.xhtml/search/content/early/recent [Read the latest Profiles published in PNAS to learn more about the careers of newly elected NAS members](/cgi/adclick/?ad=52020&adclick=true&url=http%3A%2F%2Fwww.pnas.org%2Fcgi%2Fcollection%2Fprofiles%3Fck%3Dnck) [Proceedings of the National Academy of Sciences](?etoc) [16 January 2018; Vol. 115, No. 3]( ) This Week in PNAS [In This Issue]( --------------------------------------------------------------- Letters (Online Only) [Action of steroids and plant triterpenoids on CatSper Ca2+ channels in human sperm]( Christoph Brenker, Christian Schiffer, Isabel V. Wagner, Frank Tüttelmann, Albrecht Röpke, Andreas Rennhack, U. Benjamin Kaupp, and Timo Strünker [Reply to Brenker et al.: The plant triterpenoid pristimerin inhibits calcium influx into human spermatozoa via CatSper]( Nadja Mannowetz, Nadine Mundt, and Polina V. Lishko [Considering hypertonicity in the interpretation and analysis of cell type-specific gene expression pattern in the collecting duct]( Bayram Edemir [Reply to Edemir: Physiological regulation and single-cell RNA sequencing]( Lihe Chen, Jae Wook Lee, Chung-Lin Chou, Anil V. Nair, Maria A. Battistone, Teodor G. Păunescu, Maria Merkulova, Sylvie Breton, Jill W. Verlander, Susan M. Wall, Dennis Brown, Maurice B. Burg, and Mark A. Knepper --------------------------------------------------------------- Opinion [Opinion: Measuring how countries adapt to societal aging]( [Front Matter Article] Dana P. Goldman, Cynthia Chen, Julie Zissimopoulos, John W. Rowe, and the Research Network on an Aging Society Leading scientists discuss current issues. --------------------------------------------------------------- Profiles [Profile of David M. Sabatini]( Jennifer Viegas [Profile of Joachim Frank, Richard Henderson, and Jacques Dubochet, 2017 Nobel Laureates in Chemistry]( Eva Nogales --------------------------------------------------------------- Commentaries [Microbial proteins for organic material degradation in the deep ocean]( David L. Kirchman [Endless skulls most beautiful]( Daniel J. Field [Searching for the neural causes of criminal behavior]( Ralph Adolphs, Jan Gläscher, and Daniel Tranel --------------------------------------------------------------- PNAS Plus Significance Statements [PNAS Plus Significance Statements]( Brief statements written by the authors about the significance of their papers. --------------------------------------------------------------- Physical Sciences Applied Physical Sciences [Graphene-based bimorphs for micron-sized, autonomous origami machines]( [From the Cover] Marc Z. Miskin, Kyle J. Dorsey, Baris Bircan, Yimo Han, David A. Muller, Paul L. McEuen, and Itai Cohen [Evolution of real contact area under shear and the value of static friction of soft materials]( R. Sahli, G. Pallares, C. Ducottet, I. E. Ben Ali, S. Al Akhrass, M. Guibert, and J. Scheibert Biophysics and Computational Biology [Computational modeling of three-dimensional ECM-rigidity sensing to guide directed cell migration]( Min-Cheol Kim, Yaron R. Silberberg, Rohan Abeyaratne, Roger D. Kamm, and H. Harry Asada [Slow domain reconfiguration causes power-law kinetics in a two-state enzyme]( Iris Grossman-Haham, Gabriel Rosenblum, Trishool Namani, and Hagen Hofmann [Motion parallax in electric sensing]( Federico Pedraja, Volker Hofmann, Kathleen M. Lucas, Colleen Young, Jacob Engelmann, and John E. Lewis Chemistry [The prodrug of 7,8-dihydroxyflavone development and therapeutic efficacy for treating Alzheimer’s disease]( Chun Chen, Zhihao Wang, Zhentao Zhang, Xia Liu, Seong Su Kang, Ying Zhang, and Keqiang Ye Engineering [Dynamics and mechanisms of intracellular calcium waves elicited by tandem bubble-induced jetting flow]( Fenfang Li, Chen Yang, Fang Yuan, Defei Liao, Thomas Li, Farshid Guilak, and Pei Zhong [Creation of disease-inspired biomaterial environments to mimic pathological events in early calcific aortic valve disease]( Ana M. Porras, Jennifer A. Westlund, Austin D. Evans, and Kristyn S. Masters [Silk-based multilayered angle-ply annulus fibrosus construct to recapitulate form and function of the intervertebral disc]( Bibhas K. Bhunia, David L. Kaplan, and Biman B. Mandal [Unraveling submicron-scale mechanical heterogeneity by three-dimensional X-ray microdiffraction]( [Open Access Article] Runguang Li, Qingge Xie, Yan-Dong Wang, Wenjun Liu, Mingguang Wang, Guilin Wu, Xiaowu Li, Minghe Zhang, Zhaoping Lu, Chang Geng, and Ting Zhu Physics [Localizing softness and stress along loops in 3D topological metamaterials]( Guido Baardink, Anton Souslov, Jayson Paulose, and Vincenzo Vitelli --------------------------------------------------------------- Social Sciences Psychological and Cognitive Sciences [When linearity prevails over hierarchy in syntax]( [Open Access Article] Jana Willer Gold, Boban Arsenijević, Mia Batinić, Michael Becker, Nermina Čordalija, Marijana Kresić, Nedžad Leko, Franc Lanko Marušič, Tanja Milićev, Nataša Milićević, Ivana Mitić, Anita Peti-Stantić, Branimir Stanković, Tina Šuligoj, Jelena Tušek, and Andrew Nevins --------------------------------------------------------------- Biological Sciences Applied Biological Sciences [Migration-based selections of antibodies that convert bone marrow into trafficking microglia-like cells that reduce brain amyloid β]( [Open Access Article] Kyung Ho Han, Britni M. Arlian, Matthew S. Macauley, James C. Paulson, and Richard A. Lerner [Novel concept of the smart NIR-light–controlled drug release of black phosphorus nanostructure for cancer therapy]( Meng Qiu, Dou Wang, Weiyuan Liang, Liping Liu, Yin Zhang, Xing Chen, David Kipkemoi Sang, Chenyang Xing, Zhongjun Li, Biqin Dong, Feng Xing, Dianyuan Fan, Shiyun Bao, Han Zhang, and Yihai Cao Biochemistry [Atomic mutagenesis of stop codon nucleotides reveals the chemical prerequisites for release factor-mediated peptide release]( [Open Access Article] Thomas Philipp Hoernes, Nina Clementi, Michael Andreas Juen, Xinying Shi, Klaus Faserl, Jessica Willi, Catherina Gasser, Christoph Kreutz, Simpson Joseph, Herbert Lindner, Alexander Hüttenhofer, and Matthias David Erlacher [Structure of HIV-1 reverse transcriptase cleaving RNA in an RNA/DNA hybrid]( Lan Tian, Min-Sung Kim, Hongzhi Li, Jimin Wang, and Wei Yang Biophysics and Computational Biology [Dynamics and mechanisms of intracellular calcium waves elicited by tandem bubble-induced jetting flow]( Fenfang Li, Chen Yang, Fang Yuan, Defei Liao, Thomas Li, Farshid Guilak, and Pei Zhong [Computational modeling of three-dimensional ECM-rigidity sensing to guide directed cell migration]( Min-Cheol Kim, Yaron R. Silberberg, Rohan Abeyaratne, Roger D. Kamm, and H. Harry Asada [Slow domain reconfiguration causes power-law kinetics in a two-state enzyme]( Iris Grossman-Haham, Gabriel Rosenblum, Trishool Namani, and Hagen Hofmann [Folding of maltose binding protein outside of and in GroEL]( [Open Access Article] Xiang Ye, Leland Mayne, Zhong-yuan Kan, and S. Walter Englander [Identification of a ubiquitin-binding interface using Rosetta and DEER]( Maxx H. Tessmer, David M. Anderson, Adam M. Pickrum, Molly O. Riegert, Rocco Moretti, Jens Meiler, Jimmy B. Feix, and Dara W. Frank [CDC42 binds PAK4 via an extended GTPase-effector interface]( Byung Hak Ha and Titus J. Boggon [Cargo navigation across 3D microtubule intersections]( Jared P. Bergman, Matthew J. Bovyn, Florence F. Doval, Abhimanyu Sharma, Manasa V. Gudheti, Steven P. Gross, Jun F. Allard, and Michael D. Vershinin Cell Biology [Creation of disease-inspired biomaterial environments to mimic pathological events in early calcific aortic valve disease]( Ana M. Porras, Jennifer A. Westlund, Austin D. Evans, and Kristyn S. Masters Developmental Biology [Hypoxia-induced transcription factor signaling is essential for larval growth of the mosquito Aedes aegypti]( [Inaugural Article] Luca Valzania, Kerri L. Coon, Kevin J. Vogel, Mark R. Brown, and Michael R. Strand Ecology [Organic matter processing by microbial communities throughout the Atlantic water column as revealed by metaproteomics]( [Open Access Article] Kristin Bergauer, Antonio Fernandez-Guerra, Juan A. L. Garcia, Richard R. Sprenger, Ramunas Stepanauskas, Maria G. Pachiadaki, Ole N. Jensen, and Gerhard J. Herndl [Aridity weakens population-level effects of multiple species interactions on Hibiscus meyeri]( Allison M. Louthan, Robert M. Pringle, Jacob R. Goheen, Todd M. Palmer, William F. Morris, and Daniel F. Doak Environmental Sciences [High fire-derived nitrogen deposition on central African forests]( Marijn Bauters, Travis W. Drake, Hans Verbeeck, Samuel Bodé, Pedro Hervé-Fernández, Phoebe Zito, David C. Podgorski, Faustin Boyemba, Isaac Makelele, Landry Cizungu Ntaboba, Robert G. M. Spencer, and Pascal Boeckx Evolution [Pairwise comparisons across species are problematic when analyzing functional genomic data]( [Open Access Article] Casey W. Dunn, Felipe Zapata, Catriona Munro, Stefan Siebert, and Andreas Hejnol [Developmental origins of mosaic evolution in the avian cranium]( [Open Access Article] [From the Cover] Ryan N. Felice and Anjali Goswami Genetics [Induced GnasR201H expression from the endogenous Gnas locus causes fibrous dysplasia by up-regulating Wnt/β-catenin signaling]( Sanjoy Kumar Khan, Prem Swaroop Yadav, Gene Elliott, Dorothy Zhang Hu, Ruoshi Xu, and Yingzi Yang [Expression of an active Gαs mutant in skeletal stem cells is sufficient and necessary for fibrous dysplasia initiation and maintenance]( [Open Access Article] Xuefeng Zhao, Peng Deng, Ramiro Iglesias-Bartolome, Panomwat Amornphimoltham, Dana J. Steffen, Yunyun Jin, Alfredo A. Molinolo, Luis Fernandez de Castro, Diana Ovejero, Quan Yuan, Qianming Chen, Xianglong Han, Ding Bai, Susan S. Taylor, Yingzi Yang, Michael T. Collins, and J. Silvio Gutkind [Antagonistic regulation of trafficking to Caenorhabditis elegans sensory cilia by a Retinal Degeneration 3 homolog and retromer]( Luis A. Martínez-Velázquez and Niels Ringstad [Cyclic AMP-dependent plasticity underlies rapid changes in odor coding associated with reward learning]( Thierry Louis, Aaron Stahl, Tamara Boto, and Seth M. Tomchik Immunology and Inflammation [SRC1 promotes Th17 differentiation by overriding Foxp3 suppression to stimulate RORγt activity in a PKC-θ–dependent manner]( Subha Sen, Fei Wang, Jing Zhang, Zhiheng He, Jian Ma, Yousang Gwack, Jianming Xu, and Zuoming Sun [Affinity purification mass spectrometry analysis of PD-1 uncovers SAP as a new checkpoint inhibitor]( Michael Peled, Anna S. Tocheva, Sabina Sandigursky, Shruti Nayak, Elliot A. Philips, Kim E. Nichols, Marianne Strazza, Inbar Azoulay-Alfaguter, Manor Askenazi, Benjamin G. Neel, Adam J. Pelzek, Beatrix Ueberheide, and Adam Mor [Lymphocytes eject interferogenic mitochondrial DNA webs in response to CpG and non-CpG oligodeoxynucleotides of class C]( Björn Ingelsson, Daniel Söderberg, Tobias Strid, Anita Söderberg, Ann-Charlotte Bergh, Vesa Loitto, Kourosh Lotfi, Mårten Segelmark, Giannis Spyrou, and Anders Rosén [Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges]( [Open Access Article] Barbara Piasecka, Darragh Duffy, Alejandra Urrutia, Hélène Quach, Etienne Patin, Céline Posseme, Jacob Bergstedt, Bruno Charbit, Vincent Rouilly, Cameron R. MacPherson, Milena Hasan, Benoit Albaud, David Gentien, Jacques Fellay, Matthew L. Albert, Lluis Quintana-Murci, and the Milieu Intérieur Consortium Medical Sciences [Gene regulation and suppression of type I interferon signaling by STAT3 in diffuse large B cell lymphoma]( Li Lu, Fen Zhu, Meili Zhang, Yangguang Li, Amanda C. Drennan, Shuichi Kimpara, Ian Rumball, Christopher Selzer, Hunter Cameron, Ashley Kellicut, Amanda Kelm, Fangyu Wang, Thomas A. Waldmann, and Lixin Rui [Silk-based multilayered angle-ply annulus fibrosus construct to recapitulate form and function of the intervertebral disc]( Bibhas K. Bhunia, David L. Kaplan, and Biman B. Mandal [Noncanonical agonist PPARγ ligands modulate the response to DNA damage and sensitize cancer cells to cytotoxic chemotherapy]( Melin J. Khandekar, Alexander S. Banks, Dina Laznik-Bogoslavski, James P. White, Jang Hyun Choi, Lawrence Kazak, James C. Lo, Paul Cohen, Kwok-Kin Wong, Theodore M. Kamenecka, Patrick R. Griffin, and Bruce M. Spiegelman Microbiology [Viral discovery and diversity in trypanosomatid protozoa with a focus on relatives of the human parasite Leishmania]( Danyil Grybchuk, Natalia S. Akopyants, Alexei Y. Kostygov, Aleksandras Konovalovas, Lon-Fye Lye, Deborah E. Dobson, Haroun Zangger, Nicolas Fasel, Anzhelika Butenko, Alexander O. Frolov, Jan Votýpka, Claudia M. d’Avila-Levy, Pavel Kulich, Jana Moravcová, Pavel Plevka, Igor B. Rogozin, Saulius Serva, Julius Lukeš, Stephen M. Beverley, and Vyacheslav Yurchenko [Cross-genus rebooting of custom-made, synthetic bacteriophage genomes in L-form bacteria]( Samuel Kilcher, Patrick Studer, Christina Muessner, Jochen Klumpp, and Martin J. Loessner Neuroscience [Biphasic functions for the GDNF-Ret signaling pathway in chemosensory neuron development and diversification]( [Open Access Article] Christopher R. Donnelly, Amol A. Shah, Charlotte M. Mistretta, Robert M. Bradley, and Brian A. Pierchala [Motion parallax in electric sensing]( Federico Pedraja, Volker Hofmann, Kathleen M. Lucas, Colleen Young, Jacob Engelmann, and John E. Lewis [The prodrug of 7,8-dihydroxyflavone development and therapeutic efficacy for treating Alzheimer’s disease]( Chun Chen, Zhihao Wang, Zhentao Zhang, Xia Liu, Seong Su Kang, Ying Zhang, and Keqiang Ye [Conserved features of the primate face code]( Charles F. Stevens [Somatostatin and parvalbumin inhibitory synapses onto hippocampal pyramidal neurons are regulated by distinct mechanisms]( Meryl E. Horn and Roger A. Nicoll [Detection of synchronous brain activity in white matter tracts at rest and under functional loading]( Zhaohua Ding, Yali Huang, Stephen K. Bailey, Yurui Gao, Laurie E. Cutting, Baxter P. Rogers, Allen T. Newton, and John C. Gore [Lesion network localization of criminal behavior]( [Open Access Article] [From the Cover] R. Ryan Darby, Andreas Horn, Fiery Cushman, and Michael D. Fox [Removal of perineuronal nets disrupts recall of a remote fear memory]( [Open Access Article] [From the Cover] Elise Holter Thompson, Kristian Kinden Lensjø, Mattis Brænne Wigestrand, Anders Malthe-Sørenssen, Torkel Hafting, and Marianne Fyhn Physiology [Estrogen-dependent epigenetic regulation of soluble epoxide hydrolase via DNA methylation]( Yang-Ming Yang, Dong Sun, Sharath Kandhi, Ghezal Froogh, Jian Zhuge, Weihua Huang, Bruce D. Hammock, and An Huang Plant Biology [KLU suppresses megasporocyte cell fate through SWR1-mediated activation of WRKY28 expression in Arabidopsis]( Lihua Zhao, Hanyang Cai, Zhenxia Su, Lulu Wang, Xinyu Huang, Man Zhang, Piaojuan Chen, Xiaozhuan Dai, Heming Zhao, Ravishankar Palanivelu, Xuemei Chen, and Yuan Qin Psychological and Cognitive Sciences [Motor dexterity and strength depend upon integrity of the attention-control system]( [Open Access Article] Paul Rinne, Mursyida Hassan, Cristina Fernandes, Erika Han, Emma Hennessy, Adam Waldman, Pankaj Sharma, David Soto, Robert Leech, Paresh A. Malhotra, and Paul Bentley Sustainability Science [Preservation of the genetic diversity of a local common carp in the agricultural heritage rice–fish system]( [Open Access Article] Weizheng Ren, Liangliang Hu, Liang Guo, Jian Zhang, Lu Tang, Entao Zhang, Jiaen Zhang, Shiming Luo, Jianjun Tang, and Xin Chen Systems Biology [Engineering posttranslational proofreading to discriminate nonstandard amino acids]( [Open Access Article] Aditya M. Kunjapur, Devon A. Stork, Erkin Kuru, Oscar Vargas-Rodriguez, Matthieu Landon, Dieter Söll, and George M. Church --------------------------------------------------------------- Corrections (Online Only) [Correction for Alonso-Mora et al., On-demand high-capacity ride-sharing via dynamic trip-vehicle assignment]( [Correction for Boxell et al., Greater Internet use is not associated with faster growth in political polarization among US demographic groups]( --------------------------------------------------------------- Retraction (Online Only) [Retraction for Chanmanee et al., Solar photothermochemical alkane reverse combustion]( [Cover] Open Access From the Cover Inaugural Article Classic Cozzarelli Prize Winner Front Matter --------------------------------------------------------------- This message was sent to {EMAIL}. [Unsubscribe]( from or [edit]( your subscription for this service. Or by mail: Customer Service * 973 University Avenue * Los Gatos, CA 95032 * U.S.A. Copyright © 2018 by the National Academy of Sciences