Weâve got one more bite of the NFL Week 11 DFS apple as the Arizona Cardinals play host to the San Francisco 49ers for a classic NFC West battle on Monday Night Football in Mexico City. ~/AAAHagA~/RgRlXjDJP0QuaHR0cHM6Ly93d3cuZmFudGFzeWFsYXJtLmNvbS8_bGlkPTVsNmhka3FvbHhod1cFc3BjZXVCCmN0yat7YwPm2u9SG3RyaXN0cmFtYmFsZHdpbjkyQGdtYWlsLmNvbVgEAAABRA~~ November 21, 2022 ~/AAAHagA~/RgRlXjDJP0QuaHR0cHM6Ly93d3cuZmFudGFzeWFsYXJtLmNvbS8_bGlkPWlkaWdneTY3N3Y5dFcFc3BjZXVCCmN0yat7YwPm2u9SG3RyaXN0cmFtYmFsZHdpbjkyQGdtYWlsLmNvbVgEAAABRA~~ November 21, 2022 ~/AAAHagA~/RgRlXjDJP0QuaHR0cHM6Ly93d3cuZmFudGFzeWFsYXJtLmNvbS8_bGlkPTd2djhua3MwcWNya1cFc3BjZXVCCmN0yat7YwPm2u9SG3RyaXN0cmFtYmFsZHdpbjkyQGdtYWlsLmNvbVgEAAABRA~~ MNF DFS Showdown Playbook Howard Bender [Follow on Twitter](~/AAAHagA~/RgRlXjDJP0QfaHR0cHM6Ly90d2l0dGVyLmNvbS9yb3RvYnV6emd1eVcFc3BjZXVCCmN0yat7YwPm2u9SG3RyaXN0cmFtYmFsZHdpbjkyQGdtYWlsLmNvbVgEAAABRA~~) ~/AAAHagA~/RgRlXjDJP0SjaHR0cHM6Ly93d3cuZmFudGFzeWFsYXJtLmNvbS9hcnRpY2xlcy9uZmwvc2hvd2Rvd24tcGxheWJvb2svbmZsLWRmcy13ZWVrLTExLW1vbmRheS1uaWdodC1mb290YmFsbC1zaG93ZG93bi1wbGF5Ym9vay1zYW4tZnJhbmNpc2NvLTQ5ZXJzLWF0LWFyaXpvbmEtY2FyZGluYWxzLzEzNzczN1cFc3BjZXVCCmN0yat7YwPm2u9SG3RyaXN0cmFtYmFsZHdpbjkyQGdtYWlsLmNvbVgEAAABRA~~ Weâve got one more bite of the NFL Week 11 DFS apple as the Arizona Cardinals play host to the San Francisco 49ers for a classic NFC West battle on Monday Night Football in Mexico City. It may be a bit tricky building your DFS Showdown lineups for this game as reports list Cardinals quarterback Kyler Murray as a true game-time decision which means we arenât 100-percent sure as to how everything will line up should Colt McCoy be under center. If you are a multi-lineup player, it shouldnât be too much of a problem as you can raise or lower your exposure to certain players, but if you are a one-lineup player, you should probably grab a placeholder for your contests, build a few different lineups according to the news you currently have and be able to pivot once the team makes their announcement during pre-game warm-ups. Itâs not ideal, but then again, this was the way Week 11 went for most people anyway. Christian McCaffrey, RB San Francisco 49ersMcCaffrey is a pretty obvious choice for the top spot in your lineup as there are numerous things working in his favor. The Cardinals may only allow an average of 110.5 rushing yards per game, but theyâve allowed 12 rushing touchdowns on the year. In addition to that, Arizona ranks 30th in DVOA against running back pass-plays and allow the 12th-most fantasy points per game to the running back position. Brandon Aiyuk, WR San Francisco 49ersWeâve seen a bit of a shift in the targets pecking order and itâs not just about McCaffrey coming in and taking away touches and targets. Over the last four games, Aiyuk has paced the receivers with 35 targets which heâs turned into an average of seven catches for 82 yards per game with three touchdowns. He gets moved around a lot, but we should see him opposite Trayvon Mullen most of the time and thatâs a favorable one, for sure. Rondale Moore, WR Arizona CardinalsWhile we may not know who is quarterbacking the Cardinals until closer to game time, we can at least take solace in knowing that, if Hopkins is at less than 100-percent, Moore is going to see a significant target share in this game. The 49ers defense is strong, but they do struggle against slot receivers, ranking 31st in DVOA against them this season. Moore has seen 31 targets over his last three games which shows you that, no matter who is under center, heâs getting the work. 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