Read the Special Issue: Immune Responses to Gene and Cell Therapy

Can't see this email properly? [Click here to view an online version]( [Molecular Therapy]( [American Society of Gene & Cell Therapy]( Special Issue: Immune Responses to Gene and Cell Therapy [View the full Special Issue]( Immune responses represent major complications in gene and cell therapy. Conversely, gene and cell therapies may be specifically designed to achieve an effective immune response against cancer or infectious disease or to induce immune tolerance. This special issue provides cutting-edge information on immune response mechanisms against major gene therapy vectors and gene-modified transplanted cells, interactions between the immune system and virotherapy, and cell-based immunotherapies. We hope you enjoy reading the papers in this special issue. Below is a selection of articles. Editorial - [Immunology of Gene and Cell Therapy]( Commentaries - [Did Dendritic Cell Activation, Induced by Adenovirus-Antibody Complexes, Play a Role in the Death of Jesse Gelsinger?]( - [Codon Modification and PAMPs in Clinical AAV Vectors: The Tortoise or the Hare?]( Original articles - [Adenovirus-Antibody Complexes Contributed to Lethal Systemic Inflammation in a Gene Therapy Trial]( - [A High-Throughput Method for Characterizing Novel Chimeric Antigen Receptors in Jurkat Cells]( - [Induction of Transient Virus Replication Facilitates Antigen-Independent Isolation of SIV-Specific Monoclonal Antibodies]( - [Suprachoroidal and Subretinal Injections of AAV Using Transscleral Microneedles for Retinal Gene Delivery in Nonhuman Primates]( - [Successful Transduction with AAV Vectors after Selective Depletion of Anti-AAV Antibodies by Immunoadsorption]( - [Sirt1-Overexpressing Mesenchymal Stem Cells Drive the Anti-tumor Effect through Their Pro-inflammatory Capacity]( - [Digital PCR Assays for Precise Quantification of CD19-CAR-T Cells after Treatment with Axicabtagene Ciloleucel]( - [Cardiac Nestin+ Mesenchymal Stromal Cells Enhance Healing of Ischemic Heart through Periostin-Mediated M2 Macrophage Polarization]( - [Point Mutations in Retargeted gD Eliminate the Sensitivity of EGFR/EGFRvIII-Targeted HSV to Key Neutralizing Antibodies]( - [Human iPSC-Derived Neural Crest Stem Cells Exhibit Low Immunogenicity]( Reviews - [Therapeutic Mesenchymal Stromal Cells for Immunotherapy and for Gene and Drug Delivery]( - [Manufacturing Dendritic Cells for Immunotherapy: Monocyte Enrichment]( - [Oncolytic Viruses and the Immune System: The Dynamic Duo]( [View the full Special Issue]( This message has been sent to {EMAIL} from Elsevier Communications on behalf of Cell Press. If you no longer wish to receive messages of this nature from us in the future, please [click here](. Copyright © 2020 [Elsevier B.V.](. All rights reserved. | [Elsevier Privacy Policy]( Elsevier B.V. Registered Office: Radarweg 29, 1043 NX Amsterdam, The Netherlands. Reg. No. 33158992 – Netherlands. VAT No. NL 005033019B01.