Protect your memory with one simple step

You won’t hear this from most traditionally trained doctors...but Alzheimer’s is largely an insulin problem. [Click here](1770d7/ct0_0/1/ms?sid=TV2%3ARQEe6BM4f) to view this message in your browser | [Click here](1770d7/l-002e/zout?sid=TV2%3ARQEe6BM4f) to stop receiving our messages [] [] Al Sears, MD 11905 Southern Blvd. Royal Palm Beach, FL 33411 [] August 28, 2023 [] Reader, You won’t hear this from most traditionally trained doctors...but Alzheimer’s is largely an insulin problem. And it begins with glucose. You see, glucose is essential to the proper functioning of your brain cells. Even though your brain makes up only 2% of your entire body mass, it uses 50% of the glucose in your body.1 In other words, if glucose can’t get into the cells, your brain becomes starved of the fuel it needs. This results in: - Inflammation and oxidative stress - Neurons that can’t repair themselves. - Memory loss, mild cognitive impairment, and Alzheimer’s2 Let me explain... Your body doesn’t just produce insulin in your pancreas – it also makes it in your brain. And both the insulin and insulin receptors in your brain are crucial for learning and memory. But when you over-indulge grains and processed sugars, your brain gets overwhelmed by high levels of insulin. Eventually, insulin signaling shuts down, and glucose can’t fuel your brain cells. Research now proves that insulin resistance is intrinsically linked to the development of Alzheimer’s – as well as the condition I call Syndrome Zero.3 I consider it to be the most urgent public health threat of our time. Syndrome Zero is at the root of almost every chronic disease we face today — including obesity, heart disease, cancer, arthritis, high blood pressure, metabolic syndrome, diabetes, and Alzheimer’s. In a study published in the Journal Neurology, researchers looked at brain scans from 150 middle-aged adults. They found that people with higher levels of insulin resistance used less glucose in the hippocampus, the area of the brain most susceptible to Alzheimer’s. Your hippocampus is critical for learning new things and stockpiling long-term memories. It’s also one of the areas of the brain that first shows massive shrinkage due to Alzheimer's.4 Syndrome Zero Leads To Brain Plaques Most doctors talk about “plaques” building up in the brains of dementia patients. That’s true. Plaques are a classic hallmark of Alzheimer’s. They damage the brain, causing memory loss and confusion. But they are a symptom — not the cause. What the medical establishment continues to miss is the link between plaques and insulin… Brain plaques are a build-up of amyloid-beta. Amyloid beta is a peptide secreted by insulin, and it accumulates in the brains and pancreas of diabetes and Alzheimer’s patients. In Alzheimer’s patients, abnormal clusters of these protein fragments form between nerve cells in the brain, gumming up cognitive and memory processes.5 Amyloid beta peptides also produce brain cell-damaging toxins called oligomers. Studies show these are a big factor in Alzheimer ’s-related memory loss.6 When oligomers attach themselves to neurons, they knock out the nerve cells’ insulin receptors, causing insulin resistance in the brain. To keep your brain clear of plaques, you need a certain enzyme to break down these proteins. But your brain also uses the same enzyme to clear out insulin. It’s called an “insulin-degrading enzyme” or IDE.7 If you have Syndrome Zero, IDE is too busy clearing out insulin to break down amyloid-beta. These proteins build up into the glue-like plaques that are typical of Alzheimer’s. Treat Syndrome Zero To Protect Your Brain And Memories There is a lot you can do to save your brain. But mainstream medicine has no answer – except pushing their ineffective and harmful drugs. At the Sears Institute for Anti-Aging Medicine, I’ve been using natural therapies with great success to help my patients stay sharp well into their golden years. I’ve put together a special report that I hand out to every Alzheimer’s and Syndrome Zero patient I see. And today, I want to get this information into your hands. It’s too important not to share... To get your copy, please click on the report below. 1770d7/ct1_0/1/lu?sid=TV2%3ARQEe6BM4f To Your Good Health, Al Sears, MD, CNS --------------------------------------------------------------- References: 1. Fehm HL, Kern W, Peters A. “The selfish brain: competition for energy resources.” Prog Brain Res. 2006;153:129-40. 2. Angeles V, et al. “Inflammation and insulin resistance as risk factors and potential therapeutic targets for Alzheimer’s.” Front Neurosci. 2021:15. 3. Watson GS, Craft S. “The role of insulin resistance in the pathogenesis of Alzheimer's disease: implications for treatment.” CNS Drugs. 2003;17(1):27-45. 4. Auriel A, et al. “Association of insulin resistance with cerebral glucose uptake in late middle–aged adults at risk for Alzheimer disease.” JAMA Neurology. 2015; DOI: 10.1001/jamaneurol.2015.0613 5. Hayden MR, Tyagi SC. “A is for amylin and amyloid in type 2 diabetes mellitus.” JOP. 2001 Jul;2(4):124-39. 6. Bitel CL, et al. “Amyloid-β and tau pathology of Alzheimer's disease induced by diabetes in a rabbit animal model.” Journal of Alzheimer’s Disease. 2012;32(2):291-305. 7. Schilling MA. "Unraveling Alzheimer’s: Making Sense of the Relationship between Diabetes and Alzheimer’s Disease." Journal of Alzheimer's Disease, 2016: vol. 51, no. 4, pp. 961-977. alsearsmd@send.alsearsmd.com [Preferences | Unsubscribe](1770d7/l-002e/zout?sid=TV2%3ARQEe6BM4f) 11905 Southern Blvd., Royal Palm Beach, Florida 33411, United States