There has been a huge spike in the number of Americans aged 65 and older who use cannabinoid products. [Click here](1770d7/ct0_0/1/ms?sid=TV2%3AiiUHzNYOX) to view this message in your browser | [Click here](1770d7/l-002e/zout?sid=TV2%3AiiUHzNYOX) to stop receiving our messages [] [] Al Sears, MD
11905 Southern Blvd.
Royal Palm Beach, FL 33411 [] June 23, 2023 [] Reader, There has been a huge spike in the number of Americans aged 65 and older who use cannabinoid products. In fact, in the last few years, the number of Baby Boomers who say theyâve turned to this natural pain alternative has skyrocketed by 83%.1 Thatâs more than 2 million seniors using CBD or some other kind of cannabinoid on any given day. Itâs a huge number. But todayâs seniors are turning to this herb because science proves it works. Numerous clinical trials are discovering that CBD can help combat and treat the diseases and ailments we associate with aging, including: - Alzheimerâs: In a breakthrough study published in the Journal of Alzheimerâs Disease, researchers found that supplementing with CBD for two weeks can restore the function of two proteins associated with reducing â and even eliminating â amyloid-beta plaque accumulation in the brain. These proteins, TREM2 and IL-33, play an important role in the brainâs ability to clear away and destroy dead cells and other debris that builds up in patientsâ brains. Levels of both of these proteins are diminished in patients with Alzheimerâs.2 - Diabetes: According to researchers at the Hebrew University of Jerusalem, islet cells in the pancreas â where insulin is produced â have the most CBD receptors of any part of your body. A five-year study found that when these receptors are activated with CBD, patients had 16% lower fasting insulin levels and 17% lower levels of insulin resistance.3 But the benefits donât stop there. Additional research found that CBD can: - Lower fasting insulin levels
- Help reduce obesity and lower BMI
- Increase levels of good cholesterol
- Reduceneuropathic pain
- Cancer: Breakthrough research has found that CBD works as a powerful anti-cancer agent. In a process called apoptosis, CBD caused cancer cells to essentially commit suicide. And it worked without harming normal, healthy cells, according to the National Cancer Institute. CBD also works by starving developing cancer cells. In a process called angiogenesis, newly developed cancer cells release chemicals that cause more blood vessels to form. This keeps the tumors well-fed. But research shows CBD can stop angiogenesis, starve the tumor cell, and limit spread. - Heart disease and stroke: According to research published in the British Journal of Clinical Pharmacology, CBD appears to act as a vascular-protector. In other words, it can help improve the performance of arteries, and regular use appears to reduce tissue damage when blood is suddenly cut off (known as ischemia) during a heart attack or stroke. - Erectile dysfunction. Researchers at Thomas Jefferson University found that CBD can make sex more enjoyable by boosting the libido. There are many cannabinoid receptors in the reproductive organs and sexual tissue. CBD helps to relax blood vessels, increasing blood flow to tissues. This enhances sensitivity and promotes the bodyâs natural lubrication. CBD also helps balance hormones. Because CBD regulates the endocannabinoid system, it can help manage estrogen and progesterone levels during PMS, perimenopause, and menopause. With those hormone levels in check, libido usually returns. But the benefits donât stop there. Cannabinoids, including CBD, treat many more diseases associated with aging, including a weak immune system,4 Parkinsonâs,5 arthritis,6 multiple sclerosis,7 and inflammation8 â the root cause of almost every chronic disease of our times. Get the most healing benefits from your CBD Sadly, most people who use CBD are only getting a tiny fraction of its benefits. In fact, the most common kind of CBD delivery system â oil â canât reach the cell membrane. That means youâre not getting all of the benefits of CBD. Iâve discovered that an oral spray that uses nanotechnology is the most bioavailable. Thatâs because itâs a quicker, more direct route to the bloodstream and avoids the liverâs âfirst passâ effect, lowering CBD bioavailability. To get maximum benefit, spray the liquid under your tongue, hold it without talking for 60 seconds, and then swallow. Here are a couple more ways to increase absorption. - Look for full-spectrum CBD. Terpenes are fatty oils found in the essential oils of almost all plants. They occur naturally in hemp and are extracted along with CBD and other compounds to create full-spectrum CBD products. These compounds work together and amplify each otherâs benefits, a synergy known as the âentourage effect.â Terpenes increase CBD bioavailability and enhance the therapeutic effects of cannabinoids. - Take it with healthy fats. CBD is a fat-soluble compound, meaning it dissolves in fats. This breaks CBD down into smaller molecules that are more easily absorbed by the body. One way to increase CBDâs bioavailability is to mix it with a healthy high-fat snack or meal. A recent study found that people who took CBD with high-fat foods increased their absorption up to 14 times more than those who took it on an empty stomach.9 To Your Good Health, Al Sears, MD, CNS --------------------------------------------------------------- References: 1. Han B and Palamar J. âTrends in cannabis use among older adults in the United States.â JAMA Intern Med. 2020;180(4):609-611.
2. Salk News. âCannabinoids remove plaque-forming Alzheimerâs proteins from brain cells.â 2016. . Accessed on June 7, 2023.
3. Penner E, at al. âThe impact of marijuana use on glucose, insulin and insulin resistance among US adults.â Am J Med. 126(7);583-9.
4. Maggirwar S, Khalsa J. âThe link between cannabis use, immune system, and viral infections.â Viruses. 2021 Jun; 13(6): 1099.
5. Vallee A, et al. âPotential role of cannabidiol in Parkinsonâs disease by targeting the WNT/β-catenin pathway, oxidative stress and inflammation.â Aging (Albany NY). 2021 Apr 15; 13(7): 10796â10813.
6. Frane N, et al. âCannabidiol as a treatment for arthritis and joint pain: an exploratory cross-sectional study.â J Cannabis Res. 2022 Aug 24;4(1):47.
7. Rudroff T, Sosnoff J. âCannabidiol to improve mobility in people with multiple sclerosis.â Front Neurol. 2018;9:183.
8. Nagarkatti P, et al. âCannabinoids as novel anti-inflammatory drugs.â Future Med Chem. 2009 Oct; 1(7): 1333â1349.
9. Birnbaum AK, et al. âFood effect on pharmacokinetics of cannabidiol oral capsules in adult patients with refractory epilepsy.â Epilepsia. 2019;60(8):1586-1592. alsearsmd@send.alsearsmd.com [Preferences | Unsubscribe](1770d7/l-002e/zout?sid=TV2%3AiiUHzNYOX) 11905 Southern Blvd., Royal Palm Beach, Florida 33411, United States