As a regular reader of my letters, you know thereâs a big difference between âbeingâ old and âfeelingâ old. [Click here](1770d7/ct0_0/1/ms?sid=TV2%3AiM9793kTK) to view this message in your browser | [Click here](1770d7/l-002e/zout?sid=TV2%3AiM9793kTK) to stop receiving our messages [] [] Al Sears, MD
11905 Southern Blvd.
Royal Palm Beach, FL 33411 [] November 3, 2022 [] Reader, As a regular reader of my letters, you know thereâs a big difference between âbeingâ old and âfeelingâ old. Many people survive well into their 80s, 90s, and beyond... but their lives arenât much better for it. Aging takes its toll on their mental faculties, and âsenior momentsâ get worse and worse. However, some buck that trend â keeping their sharp wit and mental stamina their whole lives. Fortunately, research shows us that you donât have to âfeelâ your age if you take the right steps. And now, an exciting new study is shedding light on another way âsuper-agersâ keep their brains active and strong. In a study published in The Journal of Neuroscience, scientists found that neurons in the area of the brain responsible for memory were noticeably larger in âsuper-agersâ compared to their peers.1 In fact, the super-agers had larger neurons than some individuals 20 to 30 years younger! The researchers examined neurons located in the entorhinal cortex. Thatâs the area of the brain whose functions include navigation, time perception, and memory. The super-agers, who were 80 and older, were compared to cognitively average individuals and those with early-stage Alzheimerâs disease. In addition to being large and healthy, the neurons found in the super-agersâ brains were relatively free of tau tangles, one of the classic physical symptoms of cognitive decline. Of course, the medical establishment likes to shrug off super-agers as people who won some genetic lottery. And while everyoneâs biology is a little different, studies show you can increase the size of your own brain, no matter how old you are. And one of the best ways is by doing the right kind of workout. For nearly three decades, Iâve been helping my patients boost their brain health, stay sharp, and improve their memory at any age. In all that time, Iâve found that one of the best strategies is to stay active. And science backs me up on this⦠A new study from McMaster University proves that high-intensity exercise improves memory. Researchers divided a group of 64 sedentary but otherwise healthy adults into three groups. One group did intense interval training. A second group did moderate exercise. The third control group simply stretched.2 After 12 weeks, the people who exercised with high intensity saw their memory improve as much as 30%.
Those who engaged in moderate exercise or only stretching saw no improvement. In an earlier study from the same university, researchers found that those who engaged in a high-intensity workout program increased their supply of brain-derived neurotrophic factor (BDNF). BDNF is like a âgrowth hormoneâ for the brain. It increases the creation and growth of nearly every type of neuron. It also increases the lifespan of existing neurons. And it helps the brain develop new neural connections called synapses.3 One study showed that people with the highest levels of BDNF develop dementia 50% less often than people with lower levels.4 In the McMaster study, the high-intensity sessions included four sets of exercise for four minutes, followed by a recovery period. Thatâs similar to my PACE program... but itâs not as effective as it could be. [Click here to read. I recommend doing PACE over high-intensity workouts.](1770d7/ct1_0/1/lu?sid=TV2%3AiM9793kTK) Practice PACE to Maximize Your Brain Power At the Sears Institute for Anti-Aging Medicine, trials clearly show that short periods of exercise leaving you panting for breath are far superior for initiating growth and self-repair, plus greater BDNF production. PACE is safe at any age. And it doesnât matter if youâre out of shape. You start out easy, at your own level. Gradually, you increase your intensity as each move becomes easier. I often recommend that patients begin with my favorite beginner move. - Stand upright with your legs together, arms extended in front of your chest, and elbows bent.
- Lift your right knee toward your left elbow. At the same time, swing your right arm down and behind you.
- Return to starting position.
- Repeat the motion on the other side. Alternate those two marching-style movements until you reach your desired intensity. Then rest and recover. Start slowly. It may take you a few sessions to build your strength and endurance. Thatâs OK. Youâre boosting your brain the whole time. To really maximize your PACE workout, I suggest coming to the Sears Institute for Anti-Aging Medicine if youâre in the South Florida area. I want to invite you to try out your first PACE class for free. My son, a certified PACE instructor, teaches each class. Dylan has helped hundreds of patients transform their lives, bodies, and brains. Call my clinic at 561-784-7852 and let my staff know when you want to come in to the practice for your first free class. To Your Good Health, Al Sears, MD, CNS --------------------------------------------------------------- References: 1. Nassif C, et al. âIntegrity of neuronal size in the entorhinal cortex is a biologic substrate of exceptional cognitive aging.â J Neurosci. 2022 Sep 26;JN-RM-0679-22.
2. Kovacevic A, et al. âThe effects of aerobic exercise intensity on memory in older adults.â Appl Physiol Nutr Metab. 2020 Jun;45(6):591-600.
3. Heisz JJ, et al. âThe effects of physical exercise and cognitive training on memory and neurotrophic factors.â J Cogn Neurosci. 2017; 29 (11):1895-1907.
4. Weinstein G, et al. âSerum brain-derived neurotrophic factor and the risk for dementia: The Framingham Heart Study.â JAMA Neurol. 2014;71(1):55-61.
5. De la Rosa A, et al. âPhysical exercise in the prevention and treatment of Alzheimerâs disease.â J Sport Health Sci. 2020; 9(1): 394â404. --------------------------------------------------------------- alsearsmd@send.alsearsmd.com [Preferences | Unsubscribe](1770d7/l-002e/zout?sid=TV2%3AiM9793kTK) 11905 Southern Blvd., Royal Palm Beach, Florida 33411, United States