Big Pharma and the FDA FAILED you

New research reveals the secret to defeating Alzheimer’s lies deep inside your own body – [Click here](1770d7/ct0_0/1/ms?sid=TV2%3AU0aW9zKCi) to view this message in your browser | [Click here](1770d7/l-002e/zout?sid=TV2%3AU0aW9zKCi) to stop receiving our messages [] [] Al Sears, MD 11905 Southern Blvd. Royal Palm Beach, FL 33411 [] August 7, 2024 [] Reader, New research reveals the secret to defeating Alzheimer’s lies deep inside your own body – and not in Big Pharma’s “breakthrough” drugs. Of course, this study is unwelcome news to Big Pharma and their shareholders. They’ve been lining their pockets for years pushing drugs that not only don’t work… But in many cases, have made things worse for sufferers of this dreadful mind-wasting disease.1,2 The truth is tens of billions of dollars — including more than $3.7 billion last year3 — have been poured into Alzheimer’s research over the past decade. Yet none of them have brought us one step closer to finding a cure or stopping the unprecedented global explosion of Alzheimer’s. In fact, the failure rate for Alzheimer's drugs is a staggering 98%.4 A Breakthrough Brain Discovery Researchers at Ben-Gurion University have made an astonishing discovery. They confirmed that the root of Alzheimer’s lies in your mitochondria, the tiny energy powerhouses found in each one of your cells.5,6 Piggybacking on the growing body of evidence that has linked mitochondrial dysfunction to Alzheimer’s, the team used mouse models to target a mitochondrial gatekeeper called VDAC1. This protein controls how these little powerpacks function, as well as the life and death of the cell itself. The researchers found that the mice that produced an excess of VDAC1 in their brain cells suffered mitochondrial and cell death. This triggered an autoimmune response leading to neuroinflammation. This neuroinflammation led to the release of neurotoxins that resulted in amyloid plagues and nerve tangles. Of course, these are key symptoms – but not the cause – of Alzheimer’s disease. By targeting VDAC1 with a special molecule that binds to the protein, the researchers prevented the changes that led to mitochondrial dysfunction and Alzheimer’s. This is great news... It means you now have the ability to prevent this dreadful disease from striking. Discover The Super Nutrient For Your Brain’s Mitochondria It’s no wonder my team and I have had such success treating Alzheimer’s patients at the Sears Institute for Anti-Aging Medicine. I’ve been recommending natural therapies that target the mitochondria for years. A key nutrient for boosting your brain’s power comes from PQQ – a nutrient I’m already using with my own patients to improve their everyday energy. You see, PQQ is the first nutrient ever discovered that multiplies the number of mitochondria in your cells. Mitochondria are the “power plants” in your cells that generate all of the energy you use to get through your day. As you get older, mitochondria become weak and start to disappear. As the most energy-hungry organ in your body, your brain cells have more than 2,000 mitochondria in each nerve cell. And healthy brains need well-functioning mitochondria. But as you grow older, your mitochondria become weaker and then die. This is a major cause of aging and the cause of many neurodegenerative disorders, like Parkinson’s, Alzheimer’s, and dementia.7,8 Recent studies reveal that your brain is a prime target for mitochondrial decay – more than any other part of your body.9 This happens because the high-energy demands of your brain cells — and their constant exposure to large amounts of oxygen — make them vulnerable to damage from free radicals and oxidative stress.10 When the damage becomes severe enough, brain cells trigger the destruction of their own mitochondria.11 Fewer mitochondria in your brain cells mean you lose your capacity to make energy… And your mental performance begins to decline. Ultimately, this sets your brain cells on the path to “cell suicide.” This loss of cells in brain tissue impacts your mobility, your ability to learn, and your memory, causing all kinds of brain disorders.12 PQQ Protects Your Brain In 3 Ways PQQ works in three ways… - Mitochondria have their own supply of DNA, and if you supply them with PQQ, they start multiplying within each of your cells. PQQ triggers your aging brain cells to grow new mitochondria. And it is this process of “mitochondrial biogenesis” that halts and reverses cell death and brain degeneration. PQQ is the only nutrient that can do this. - PQQ also protects the existing mitochondria in your brain cells by working to mop up free radicals and the oxidative stress damage in brain tissue — the very things that kill mitochondria in the first place. - At the same time, PQQ stimulates the production of nerve growth factor (NGF) which triggers the growth of new brain cells and branching of nerve cells.13,14 To Your Good Health, Al Sears, MD, CNS P.S. This energy crisis and its link to the epidemic of chronic diseases affecting our country is so important that I want to talk directly to you. So I’ve recorded a short video series. Earlier this morning, in PART ONE, I showed you how you can breathe new life into your aging mitochondria. If you didn’t see it, don’t worry. I’ve uploaded a link so you can watch it now. Just click on this video to get started. [screenshot](1770d7/ct1_0/1/lu?sid=TV2%3AU0aW9zKCi) P.P.S. And don’t forget to join me for a MAIN event to discuss America’s low-energy epidemic. It’s called Reclaim Your Youthful Energy with Dr. Sears. It’s this Friday, August 9th, at NOON Eastern. There’s no charge to join this live event. But the service that’s hosting it requires that you pre-register. Reserve your spot now so you don’t miss out! [Click here to sign up](1770d7/ct2_0/1/lu?sid=TV2%3AU0aW9zKCi). --------------------------------------------------------------- References: - Christopher H, et al. “Lecanemab in early Alzheimer’s disease.” N Engl J Med 2023; 388:9-21. - EurekaAlert. “Dementia drugs may put some patients at risk, Queen’s study shows.” Accessed 06/07/2024. - . - Tesi R. “Why do so many Alzheimer’s clinical trials fail?” www.clinicalleader.com. Accessed on June 1, 2024. - Alzheimer’s Association. www.alz.org/alzheimers-dementia/research_progress/ our_commitment. Accessed 06/07/2024. - Shoshan-Barmatz V, et al. “VDAC1, mitochondrial dysfunction, and Alzheimer’s disease” Pharmacolog Res. 2018;131. - Verma A, et al. “Targeting the overexpressed mitochondrial protein VDAC1 in a mouse model of Alzheimer’s disease protects against mitochondrial dysfunction and mitigates brain pathology.” Transl Neurodegen.2023;12(1):2. - Facecchia K, et al. “Oxidative toxicity in neurodegenerative diseases: role of mitochondrial dysfunction and therapeutic strategies.” J Toxicol. 2011;2011:683728. - Martin LJ. “Mitochondrial and cell death mechanisms in neurodegenerative diseases.” Pharmaceuticals (Basel). 2010;3(4):839-915. - Boveris A, Navarro A. “Brain mitochondrial dysfunction in aging.” IUBMB Life. 2008 May;60(5):308-14 - Szeto HH. “Mitochondria-targeted peptide antioxidants: novel neuroprotective agents.” AAPS J. 2006 Aug 18;8(3):E521-31. - Haddad DM, et al. “Mutations in the intellectual disability gene Ube2a cause neuronal dysfunction and impair parkin-dependent mitophagy.” Mol Cell. 2013 Jun 27;50(6):831-43. - Ames BN, Liu J. “Delaying the mitochondrial decay of aging with acetylcarnitine.” Ann N Y Acad Sci. 2004 Nov;1033:108-16. - Yamaguchi K, et al. “Stimulation of nerve growth factor production by pyrroloquinoline quinone and its derivatives in vitro and in vivo.” Biosci Biotechnol Biochem. 1993 Jul;57(7):1231-3. alsearsmd@send.alsearsmd.com [Preferences | Unsubscribe](1770d7/l-002e/zout?sid=TV2%3AU0aW9zKCi) 11905 Southern Blvd., Royal Palm Beach, Florida 33411, United States