New hope for diabetes

Breakthrough study finds “pharmacy in a plant” lowers blood sugar naturally [Click here](1770d7/ct0_0/1/ms?sid=TV2%3AUvlpIVis2) to view this message in your browser | [Click here](1770d7/l-002e/zout?sid=TV2%3AUvlpIVis2) to stop receiving our messages [] [] Al Sears, MD 11905 Southern Blvd. Royal Palm Beach, FL 33411 [] July 16, 2024 [] Reader, If you’re supplementing with curcumin, you’ve made a smart choice… In study after study, the whole-body healing effects of turmeric have proven to be nothing short of remarkable. I’ll let the results speak for themselves. Published peer-reviewed studies found that the spice boosts memory and protects against Alzheimer’s… fights inflammation… lowers blood pressure… improves vision… lowers the risk of heart disease… and prevents cancer.1,2,3,4,5,6,7 Now, a new study shows just how effective it is against diabetes. In a study published in the journal Cell Biochemistry and Function, a research team looked at curcumin’s impact on oxidative stress and inflammation – two of the hallmarks of diabetes. The results were jaw-dropping. The turmeric compound attacked every aspect of the disease: - It lowered blood sugar and increased insulin sensitivity - It calmed inflammatory cytokines, including TNF-α and IL-6, which make diabetes worse - It protected other organs such as the heart, lungs, and kidneys from diabetic damage To top it all off, researchers also found that curcumin helped activate NF-κB, the “master switch” for inflammation.8 Results like this are impressive. But not surprising. Curcumin’s anti-inflammatory and antioxidant properties have been well-known for years. Unfortunately, institutions bankrolled by Big Pharma have been reluctant to admit just how transformative natural solutions like curcumin can be for the world’s worst chronic diseases. With results like this, that is changing. The curcumin in turmeric can moderate or even prevent diabetes in a variety of ways. One of the ways it does this is through regulating lipid metabolism. Lipids are the fatty compounds that make up your cell membranes. They help control what goes in and out of your cells. Keeping them healthy enables them to better store energy, absorb vitamins, and make hormones. People living with diabetes have to deal with abnormally high lipid activity, which can be harmful. Curcumin can regulate lipid metabolism by lowering the triglycerides and cholesterol in the blood.9 Studies also show curcumin can improve insulin sensitivity, moderate the production of new fat cells, and lower blood pressure.10 But curcumin doesn’t just help manage diabetes. It could be the key to turning the tide when it matters most. In a study published in the journal Diabetes Care, researchers administered curcumin to people with prediabetes for nine months and compared them to a placebo group. Volunteers who received curcumin were less likely to develop type 2 diabetes – meaning their prediabetes was essentially reversed. According to the study authors, curcumin was able to improve the function of the beta cells in the pancreas – which create insulin.11 Defend Against Diabetes With Curcumin There are a number of ways to incorporate curcumin into your wellness routine. All of them will bolster your blood sugar health and your defense against diabetes – plus so much more. But if you want the full impact of curcumin, here are a few things to remember: - Find a quality supplement. The majority of curcumin supplements you find on drug store shelves just won’t work. I did a quick search of the labels of a handful of popular brands. Most had a paltry dosage of around 450 mg. I recommend a daily dose of at least 3,000 mg to ensure you get the most brain benefits from curcumin. - Take it with fat: If you’re taking a curcumin supplement with water, your body won’t absorb the compound completely. That’s why it’s best to pair your curcumin supplement with a fatty meal – preferably with 15 grams of fat or more. If you’re adding turmeric to a smoothie, make sure to use whole milk to maximize absorption. I also recommend splitting your supplement and taking 1,500 mg with a meal twice a day. - Always include black pepper extract: Bioperine, or black pepper extract, is the perfect sidekick for curcumin. This extract enhances the absorption of curcumin, so you’re getting the most out of what you’re putting into your body. Piperine is a potent inhibitor of drug metabolism. It protects the curcumin against digestive enzymes that want to remove it from your blood. Studies show that add Bioperine increases bioavailability by 2,000%.12 To Your Good Health, Al Sears, MD, CNS --------------------------------------------------------------- References: - Reddy P, et al. “Protective effects of Indian Spice Curcumin Against Amyloid Beta in Alzheimer’s Disease.” [J Alzheimer’s Dis. 2018; 61(3): 843–866.](1770d7/ct1_0/1/lu?sid=TV2%3AUvlpIVis2) - Small G, et al. “Memory and Brain Amyloid and Tau Effects of a Bioavailable Form of Curcumin in Non-Demented Adults: A Double-Blind, Placebo-Controlled 18-Month Trial.” Am J Geriatr Psychiatry. 2018 Mar;26(3):266-277. - Peng Y, et al. “Anti-Inflammatory Effects of Curcumin in the Inflammatory Diseases: Status, Limitations and Countermeasures.” [Drug Des Devel Ther.](1770d7/ct2_0/1/lu?sid=TV2%3AUvlpIVis2) 2021; 15: 4503–4525. - Karimi A, et al. “Effects of curcumin on blood pressure: A systematic review and dose-response meta-analysis.” Diseases. 2023;33(11)2089-2101. - [Radomska-Leśniewska](1770d7/ct3_0/1/lu?sid=TV2%3AUvlpIVis2) D, et al. “Therapeutic potential of curcumin in eye diseases.” [Cent Eur J Immunol.](1770d7/ct4_0/1/lu?sid=TV2%3AUvlpIVis2) 2019; 44(2): 181–189. - [Pourbagher-Shahri](1770d7/ct5_0/1/lu?sid=TV2%3AUvlpIVis2) A, et al. “Curcumin and cardiovascular diseases: Focus on cellular targets and cascades.” Biomed Pharmacother. 2021 Apr:136:111214. - Yang Z, et al. “Effects and Mechanisms of Curcumin for the Prevention and Management of Cancers: An Updated Review.” Antioxidants. 2022;11(8):1481. - Zamanian M, et al. “NF-κB pathway as a molecular target for curcumin in diabetes mellitus treatment: Focusing on oxidative stress and inflammation.” Cell Biochem Funct. 2024;42(4):e4030. - Yuan F, et al. “A systematic review and meta-analysis of randomized controlled trials on the effects of turmeric and curcuminoids on blood lipids in adults with metabolic diseases.” Adv Nutr. 2019;10(5):791-802. - Hewlings S, et al. “Curcumin: A review of its effects on human health.” Foods. 2017;6(10):92. - Chuengsmarn S, et al. “Curcumin extract for the prevention of type 2 diabetes.” Diabetes Care. 2020;35(11):2121-2127. - Shoba G, et al. “Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers.” Planta Med. 1998 May;64(4):353-6. --------------------------------------------------------------- alsearsmd@send.alsearsmd.com [Preferences | Unsubscribe](1770d7/l-002e/zout?sid=TV2%3AUvlpIVis2) 11905 Southern Blvd., Royal Palm Beach, Florida 33411, United States