I see a lot of patients with heart failure at my clinic. [Click here](1770d7/ct0_0/1/ms?sid=TV2%3A563EhRTmA) to view this message in your browser | [Click here](1770d7/l-002e/zout?sid=TV2%3A563EhRTmA) to stop receiving our messages [] [] Al Sears, MD
11905 Southern Blvd.
Royal Palm Beach, FL 33411 [] April 16, 2024 [] Reader, I see a lot of patients with heart failure at my clinic. Of course, this is hardly groundbreaking news, given that heart disease continues to be the number-one killer after more than a century. Hereâs what is groundbreaking⦠Heart failure patients will soon be able to dramatically restore their heart muscle function â thanks to a breakthrough in stem cell medicine. Traditionally trained doctors will tell you heart failure canât be cured. Then theyâll prescribe a range of meds, like diuretics, ACE inhibitors, beta-blockers, statins, and other drugs. In most cases, these drugs make the condition even worse. You see when you have heart failure, it means your heart muscle has become so weak itâs no longer able to pump as much blood as your body needs. So, the last thing you need are medications that decrease cardiac output and make it harder for your heart to pump enough oxygen around your body. Of course, these drugs also cause terrible side effects. Theyâve been linked to constant fatigue⦠shortness of breath⦠joint, leg, and back pain⦠headaches⦠heart rhythm problems⦠swelling⦠muscle pain⦠and kidney damage. Some of them can even increase your risk of a heart attack.1 Here at the Sears Institute for Anti-Aging Medicine, I donât prescribe any of these drugs. Instead, I treat patients with therapies that boost cardiac output. Iâll tell you about them in a minute. First, let me tell you about the latest stem cell research. Regular readers will also know Iâve been a fan of regenerative stem cell therapies for more than a decade. Iâve used them to help patients battle â and in some cases REVERSE â conditions including diabetes, rheumatoid arthritis, strokes, autoimmune disease, chronic pain, kidney failure, and heart failure. Thatâs why Iâm so excited by this latest stem cell breakthrough⦠It was one of the largest stem cell intervention studies following a heart attack. Last year, researchers recruited 315 patients with advanced heart failure from 39 hospitals in 10 countries â and the results were spectacular.2 Patients were randomly divided into two groups. One group received stem cell therapy while the second didnât. The stem cell patients underwent cardiac catheterization, which delivered mesenchymal stem cells â taken from their own bone marrow â directly into their heart muscle. Patients assigned not to receive stem cells also had cardiac catheterization but without cell delivery. This research strategy is known as âsham treatment.â Mesenchymal stem cells were used because they can repair muscular tissue and reduce inflammation without stimulating a dangerous immune response. The researchers, publishing in Stem Cells Translational Medicine, found that after a one-year follow-up, patients who received the stem cell therapy had a vastly improved quality of life and the damage to their heart muscle had been significantly repaired. Before the study, heart attack damage had caused the hearts of many patients to function at just 15% to 25% capacity. But just two weeks after stem cell therapy, function jumped to 55%. The study also noted lower death and hospitalization rates among those treated with stem cell therapy. The FDA should now fast-track this vital therapy so heart failure patients can benefit as quickly as possible. In the meantime, you donât have to rely on mainstream medicineâs risky drugs and wait for your life to gradually disappear. Despite what cardiologists might tell you, heart failure is highly reversible. Heart Failure Is Reversible Here are three safe and powerful nutrients I use with my patients that will boost your heartâs pumping power: - CoQ10: This is an essential nutrient for everyone â but especially for people with heart failure. CoQ10 is like high-octane fuel for your cells, and itâs essential for the normal function of all your vital organs â especially an energy-hungry organ like your heart. It works by turbo-charging your mitochondria, the little power plants inside each of your cells. Patients with heart failure already have dangerously depleted blood levels of CoQ10, because of intestinal and liver swelling. This impairs the bodyâs absorption of CoQ10. Damage caused by common heart drugs like statins, can also lower your CoQ10 levels by as much as 40%.3 That means if you suffer from heart failure, you need high doses of CoQ10. I recommend a daily dose of 400-450 mg. And make sure itâs the more powerful and bioabsorbable ubiquinol form of CoQ10.4 - PQQ: CoQ10 does an amazing job of squeezing more power out of your mitochondria. But the little-known nutrient pyrroloquinoline quinone, or PQQ, triggers your heart cells to build healthy new mitochondria. This produces more fuel, so your heart pumps with more energy. Good sources of PQQ are kiwi fruit, sweet green peppers, carrots, potatoes, cabbage, sweet potatoes, and bananas. You can also find PQQ supplements online or in health food stores. I recommend taking 10 to 20 mg of PQQ daily with your CoQ10. - D-ribose: This is a naturally occurring carbohydrate found in every living cell in the body. Without it, cells canât produce energy. And it is utterly essential to the energy levels of the muscular tissue in the heart â especially if you have heart failure. Take 5 g of powdered D-ribose three times a day. I tell my patients to mix each dose of D-ribose in eight ounces of water or juice. Then drink it down at breakfast, lunch, and dinner. To Your Good Health, Al Sears, MD, CNS --------------------------------------------------------------- References: - Chen K, et al. âTriggering of myocardial infarction by heat exposure is modified by medication intake.â Nat Cardio Res. 2022;1:727-731.
- Yamada S, et al. âCell therapy improves quality-of-life in heart failure: outcomes from a phase iii clinical trial.â Stem Cells Transl Med. 2024 Feb 14;13(2):116-124.
- Ghirlanda G, et al. âEvidence of plasma CoQ10-lowering effect of HMG-COA reductase inhibitors: a double-blind, placebo-controlled study.â J Clin Pharmacol. 1993 Mar;33(3):226-229.
- Langsjoen H, et al. âUsefulness of coenzyme Q10 in clinical cardiology: a long-term study.â Mol Aspects Med. 1994;15 Suppl: s165-75. alsearsmd@send.alsearsmd.com [Preferences | Unsubscribe](1770d7/l-002e/zout?sid=TV2%3A563EhRTmA) 11905 Southern Blvd., Royal Palm Beach, Florida 33411, United States